# ZO Skin Health Daily Power Defense for oily skin

**Lovi Fit: High fit for oily skin.**
Oily Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/uk/p/zo-skin-health/daily-power-defense/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [ZO Skin Health](https://lovi.care/skincare/uk/brands/zo-skin-health)
Category: [Serums and treatments](https://lovi.care/skincare/uk/best/serums)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for oily skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your oily skin, this formula leverages the humectant properties of glycerin and beta-glucan alongside the antioxidant activity of Arabidopsis thaliana extract to provide essential hydration and environmental protection.
- While it offers general skincare benefits and antioxidant protection with ingredients like tocopherol, it does not specifically target concerns related to oily shine.
- The product is safe for your skin, with no reported irritation risks due to the absence of harsh ingredients and the inclusion of soothing agents like Beta-Glucan.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/zo-skin-health/daily-power-defense/for/oily-skin): High (this page)
- [Dry skin](https://lovi.care/skincare/uk/p/zo-skin-health/daily-power-defense/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/uk/p/zo-skin-health/daily-power-defense/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/uk/p/zo-skin-health/daily-power-defense/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/uk/p/zo-skin-health/daily-power-defense/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/uk/p/zo-skin-health/daily-power-defense/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/uk/p/zo-skin-health/daily-power-defense/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/zo-skin-health/daily-power-defense/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/zo-skin-health/daily-power-defense/for/oily-acne-prone-skin): Average

## Key ingredients

Retinol, Beta-Glucan, Arabidopsis Thaliana Extract, Tocopheryl Acetate, Palmitoyl Tripeptide-1

## What the research says

- Topical application of photolyase-containing liposomes followed by photoreactivating light decreased UVB-induced dimers by 40-45% and prevented immunosuppression, erythema, and sunburn-cell formation in healthy human subjects. ([Proceedings of the National Academy of Sciences of the United States of America, 2000](https://pubmed.ncbi.nlm.nih.gov/10660687/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Skin care regimens containing beta-glucan improved hemoglobin index, skin hydration, and transepidermal water loss compared to vehicle control in 20 patients undergoing fractional laser therapy. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/))
- Treatment with topical formulations containing beta-glucan combined with nanofractional radiofrequency plus magnetic nanofractional radiofrequency showed the best efficacy and was tolerable and effective in Chinese women with abdominal stretch marks compared to control groups. ([Dermatology and Therapy, 2023](https://pubmed.ncbi.nlm.nih.gov/37171578/))
- Topical beta-glucan mildly improved striae gravidarum, 1565-nm non-ablative fractional laser showed better results than topical beta-glucan, and the combined strategy further improved striae gravidarum atrophy compared to single treatment. ([The Journal of Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35570397/))
- Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40642809/))
- Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate. ([Contemporary Clinical Trials Communications, 2021](https://pubmed.ncbi.nlm.nih.gov/34471722/))
- Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590207/))
- A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo. ([Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/))
- Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/))
- Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components. ([International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42683869/))

## What reviewers say

Based on limited data, this serum is highly regarded for its ability to repair the skin barrier, providing a healthy glow and improved texture. Most users appreciate its lightweight feel and hydrating properties. Some users report experiencing initial irritation or breakouts due to active ingredients, and the high price point is a frequent concern.

- Liked: Barrier repair (mostly mentioned)
- Liked: Lightweight & absorbent (often mentioned)
- Disliked: High price point (often mentioned)
- Liked: Anti-aging results (sometimes noted)
- Liked: Versatile hydration (sometimes noted)
- Disliked: Initial irritation (sometimes noted)
- Disliked: Counterfeit risk (rarely noted)
- Disliked: Scent/packaging (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week and build up to daily use if your skin tolerates it well.
- Apply the serum after cleansing and toning, but right before your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin. Let it absorb ⏱ for a minute before applying the next product.
- Apply the serum on clean and dry skin since your skin is not sensitive and you want to target oily shine. This helps control excess oil throughout the night.
- Avoid the delicate eye area and do a patch test before using the serum for the very first time.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Daily Power Defense a great fit for oily skin?

This product is a great fit for oily skin because it uses glycerin and beta-glucan to provide essential hydration without heaviness, while Arabidopsis thaliana extract delivers reliable environmental protection. It is also safe for your skin and is unlikely to cause irritation thanks to soothing agents like beta-glucan.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Proceedings of the National Academy of Sciences of the United States of America, 2000](https://pubmed.ncbi.nlm.nih.gov/10660687/)

### Which ingredients make this serum a good fit for oily skin?

Glycerin and beta-glucan provide essential hydration while Arabidopsis thaliana extract offers environmental protection, making this formula a great fit for oily skin. These ingredients keep your skin smooth and protected without causing irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Proceedings of the National Academy of Sciences of the United States of America, 2000](https://pubmed.ncbi.nlm.nih.gov/10660687/)

### What does Retinol do for oily skin?

Retinol helps oily skin by keeping pores clear and balancing sebum production, which may reduce shine and breakouts. Because it can sometimes cause dryness or peeling in the beginning, starting slowly is recommended.
Sources: [Biochimica Et Biophysica Acta, 2012](https://pubmed.ncbi.nlm.nih.gov/21914489/)

### What does Beta-Glucan do for oily skin?

This product is an average fit for oily skin because it lacks lightweight hydration and oil-controlling ingredients. Oily skin needs balancing ingredients like niacinamide or lightweight hydrators such as hyaluronic acid to stay smooth without feeling heavy.

### Where does this serum go in a skincare routine for oily skin?

This treatment goes in the evening routine after cleansing and before moisturizing, keeping application simple and safe around sun exposure. It is unlikely to cause irritation on oily skin thanks to soothing ingredients like beta-glucan.

### Can I use it with vitamin C, and in what order?

You can use this treatment alongside vitamin C by applying your vitamin C product first, letting it absorb, and then following with this formula. This approach provides your oily skin with extra antioxidant support while keeping your routine gentle and irritation-free.

### How often should I use this serum?

You can use this treatment in the evening as part of your routine. It is very safe for your skin, as it contains soothing beta-glucan and lacks harsh ingredients that could cause irritation.

### Can it clog pores, cause breakouts or purging for oily skin?

This product is a great fit for your oily skin and is unlikely to cause irritation, breakouts, or clogged pores due to its gentle, soothing ingredients like beta-glucan and lack of harsh components. It helps provide hydration and environmental protection while maintaining a very safe profile on your skin.

### Is it fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum and limonene). Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for oily skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/uk/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/oily-skin) — Superior fit — £36.96 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/uk/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/oily-skin) — Superior fit — £24.20 at Amazon
- [Dr. Ceuracle Tea Tree Purifine 95 Essence](https://lovi.care/skincare/uk/p/dr-ceuracle/tea-tree-purifine-95-essence/for/oily-skin) — Superior fit — £21.11 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/uk/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — £8.29 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/uk/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — £13.98 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/uk/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-skin) — Superior fit — £14.80 at Amazon

## Where to buy

No store in United Kingdom has a checked price for this product, so the page shows none.

## Ingredients

Water, 1,2-Hexanediol, Dicaprylyl Carbonate, Cetearyl Isononanoate, Glycerin, Pentylene Glycol, Cetearyl Alcohol, Steareth-20, Safflower Palm Aminopropanediol Esters Oil, Laminaria Digitata Extract, Opuntia Ficus-Indica Stem Extract, Arabidopsis Thaliana Extract, Marrubium Vulgare Meristem Cell Culture, Leontopodium Alpinum Meristem Cell Culture, Retinyl Palmitate, Tocopheryl Acetate, Tocopherol, Micrococcus Lysate, Caprylyl Glycol, Hexylene Glycol, Lactose, Galactoarabinan, Schizophyllan, Beta-Glucan, Carbomer, Cellulose, Maltodextrin, C14-22 Alcohols, C12-20 Alkyl Glucoside, Hydroxypropyl Methylcellulose, Disodium Edta, Sodium Hydroxide, Phenoxyethanol, Ethylhexylglycerin, Sodium Benzoate, Parfum, Ultramarines, Limonene
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/zo-skin-health/daily-power-defense/for/oily-skin
- United Kingdom: https://lovi.care/skincare/uk/p/zo-skin-health/daily-power-defense/for/oily-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/zo-skin-health/daily-power-defense/for/oily-skin
- Germany: https://lovi.care/skincare/de/p/zo-skin-health/daily-power-defense/for/oily-skin
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