# Wellage Real Hyaluronic Blue 100 Ampoule for mature skin

**Lovi Fit: Average fit for mature skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/uk/p/wellage/real-hyaluronic-blue-100-ampoule/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [Wellage](https://lovi.care/skincare/uk/brands/wellage)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/uk/best/moisturizers)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for mature skin; other moisturizers fit it better.

## Why this fit

- Offers excellent moisturizing for your normal skin due to the presence of multiple forms of hyaluronic acid, such as sodium hyaluronate and hydrolyzed hyaluronic acid, which provide superior humectant action. Glycerin further supports hydration, making it highly suitable for your skin type.
- While it provides general hydration benefits, the formula is not specifically targeted for wrinkles and fine lines, which is your main goal.
- The safety profile is excellent, with no risks of irritation for your normal skin due to the absence of harsh ingredients and the inclusion of soothing agents like Centella Asiatica Extract and Beta-Glucan.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/wellage/real-hyaluronic-blue-100-ampoule/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/uk/p/wellage/real-hyaluronic-blue-100-ampoule/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/uk/p/wellage/real-hyaluronic-blue-100-ampoule/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/uk/p/wellage/real-hyaluronic-blue-100-ampoule/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/uk/p/wellage/real-hyaluronic-blue-100-ampoule/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/uk/p/wellage/real-hyaluronic-blue-100-ampoule/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/uk/p/wellage/real-hyaluronic-blue-100-ampoule/for/mature-skin): Average (this page)
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/wellage/real-hyaluronic-blue-100-ampoule/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/wellage/real-hyaluronic-blue-100-ampoule/for/oily-acne-prone-skin): Average

## Key ingredients

Sodium Hyaluronate, Β-Glucan, Panthenol Vitamin B5, Centella Asiatica Extract, Glycerin

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Profhilo treatment led to significant improvements in superficial skin hydration and transepidermal water loss over time in Chinese females, while demonstrating good product tolerability. ([Aesthetic Plastic Surgery, 2026](https://pubmed.ncbi.nlm.nih.gov/40921777/))
- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Skin care regimens containing beta-glucan improved hemoglobin index, skin hydration, and transepidermal water loss compared to vehicle control in 20 patients undergoing fractional laser therapy. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/))
- Treatment with topical formulations containing beta-glucan combined with nanofractional radiofrequency plus magnetic nanofractional radiofrequency showed the best efficacy and was tolerable and effective in Chinese women with abdominal stretch marks compared to control groups. ([Dermatology and Therapy, 2023](https://pubmed.ncbi.nlm.nih.gov/37171578/))
- Topical beta-glucan mildly improved striae gravidarum, 1565-nm non-ablative fractional laser showed better results than topical beta-glucan, and the combined strategy further improved striae gravidarum atrophy compared to single treatment. ([The Journal of Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35570397/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Treatment with an asiaticoside-containing cream applied twice daily for 12 weeks significantly improved periorbital wrinkles in 65% of 27 female volunteers compared to a vehicle control cream. ([International Journal of Cosmetic Science, 2008](https://pubmed.ncbi.nlm.nih.gov/18452433/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))

## Why other moisturizers fit mature skin better

- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Treatment with a combination of niacinamide and hyaluronic acid improved skin aging signs and demonstrated a senomorphic effect by decreasing SASP and autocrine signaling genes in women. ([Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/))

## What reviewers say

This ampoule is highly regarded for its ability to hydrate dehydrated and oily skin types, owing to its very lightweight, water-like consistency that absorbs rapidly without any stickiness. It effectively delivers deep, buildable hydration, leading to plumper skin and reduced redness. However, individuals with very dry skin may find it insufficient on its own and may need to layer it with a richer cream or apply multiple layers for optimal results.

- Liked: Extremely lightweight (mostly mentioned)
- Liked: Deep hydration (often mentioned)
- Liked: Non-sticky finish (often mentioned)
- Liked: Gentle and soothing (sometimes noted)
- Liked: Good value (sometimes noted)
- Disliked: Insufficient for dry skin (sometimes noted)
- Disliked: Lacks dramatic results (rarely noted)
- Disliked: Potential breakouts (rarely noted)
- Disliked: Too runny texture (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help smooth fine lines.
- Apply this product after your toner and serum, but before your SPF in the morning. Follow your cleanser and toner steps to keep your skin balanced.
- Gently press a small amount into your face and neck. Avoid rubbing the skin too harshly to prevent extra tension.
- Apply the moisturizer on slightly damp skin to help lock in extra moisture. Clean skin helps the product absorb much more evenly.
- Avoid the sensitive eye area during application. Do a quick patch test before your very first use to stay safe.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does the Wellage Real Hyaluronic Blue 100 Ampoule work for mature skin?

This moisturizing treatment works for mature skin by providing general hydration, but it is not specifically targeted for wrinkles and fine lines. A product of this type needs effective anti-wrinkle and hydrating ingredients, along with skin-repairing components, to address mature skin properly.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for mature skin?

This serum contains multiple forms of hyaluronic acid, glycerin, and beta-glucan, which help keep mature skin hydrated and smooth. Because it focuses on general moisture rather than wrinkles, a product for this skin needs effective anti-wrinkle and hydrating ingredients to address aging signs while keeping skin soft.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Hyaluronic Acid do for mature skin?

Hyaluronic acid helps mature skin by deeply boosting moisture, improving elasticity, and smoothing the appearance of fine lines and wrinkles. Regular use keeps the skin looking plump and soft while supporting overall firmness and hydration.
Sources: [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/), [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38591218/)

### What does Beta Glucan do for mature skin?

Beta-glucan helps mature skin by boosting hydration, smoothing the look of fine lines, and supporting overall barrier recovery. It also acts as an antioxidant to calm the skin and protect against environmental damage.
Sources: [Phytotherapy Research, 2014](https://pubmed.ncbi.nlm.nih.gov/23494974/), [Food Science & Nutrition, 2025](https://pubmed.ncbi.nlm.nih.gov/40291929/)

### Where does this serum go in a skincare routine for mature skin?

This treatment goes in the evening routine, after cleansing and before moisturizing, though some can also be used in the morning or twice a day. While it offers good hydration, mature skin targeting wrinkles and fine lines needs products with firming peptides and antioxidants.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to hydrate your skin before putting on your retinol. Using a hydrating product beforehand helps your skin handle retinol better and is unlikely to cause irritation.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### How often should I use this serum?

This treatment works well for daily evening use to fit your mature skin, though this skin needs formulas targeting wrinkles and fine lines for the best results. Daily application helps boost moisture and comfort while remaining very gentle.
Sources: [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can this serum clog pores, cause breakouts or purging for mature skin?

This serum is unlikely to cause breakouts or clog pores for mature skin. It has a very safe formula with soothing ingredients like Centella Asiatica Extract and Beta-Glucan that help keep skin calm.

### Can I use this serum around the eyes or on my body?

You can use this moisturizing treatment around the eyes and on the body since it features a very safe formula with soothing ingredients like Centella Asiatica Extract and Beta-Glucan that are unlikely to cause irritation. However, because this product does not specifically target wrinkles and fine lines, mature skin needs a product of this type that includes ingredients and benefits focused on firming and smoothing lines.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [MISSHA Super Aqua Ultra Hyalron Ampoule](https://lovi.care/skincare/uk/p/missha/super-aqua-ultra-hyalron-ampoule/for/mature-skin) — High fit — £18.17 at Amazon
- [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/uk/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/mature-skin) — Average fit — £34.00 at Amazon
- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/uk/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/mature-skin) — Average fit — £18.40 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/uk/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — £14.99 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/uk/p/some-by-mi/snail-truecica-miracle-repair-toner/for/mature-skin) — Superior fit — £13.98 at Amazon
- SPF: [Torriden DIVE-IN Mild Sunscreen](https://lovi.care/skincare/uk/p/torriden/dive-in-mild-sunscreen/for/mature-skin) — Superior fit — £22.00 at Amazon

## Where to buy

No store in United Kingdom has a checked price for this product, so the page shows none.

## Ingredients

Water, Propanediol, Pentylene Glycol, Glycerin, 1,2-Hexanediol, Panthenol, Dioscorea Japonica Root Extract, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Coccinia Indica Fruit Extract, Piper Methysticum Stem Extract Root Leaf, Centella Asiatica Extract, Panax Ginseng Extract Berry, Solanum Melongena Fruit Extract, Aloe Barbadensis Flower Extract, Ocimum Sanctum Leaf Extract, Curcuma Longa Root Extract, Corallina Officinalis Extract, Alpinia Galanga Extract, Hydrogenated Lecithin, Methylpropanediol, Sodium Acrylic Acid Ma Copolymer, Butylene Glycol, Xanthan Gum, Sodium Citrate, Glycosyl Trehalose, Hydrogenated Hydrolysate Starch, Adenosine, Citric Acid, Raffinose, Lecithin, Polyquaternium-51, Beta-Glucan, Saccharide Isomerate, Cyanocobalamin, Biosaccharide Gum-1, Caprylic Capric Triglyceride, Sodium Stearoyl Glutamate, Sucrose Laurate, Glycine, Serine, Arginine, Histidine, Lysolecithin, Hydrolyzed Sodium Hyaluronate, Tocopherol, Benzyl Glycol, Hydrolyzed Glycosaminoglycans, Sodium Acetylated Hyaluronate, Sodium Hyaluronate Crosspolymer, Hydroxypropyltrimonium Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Ethylhexylglycerin, Caprylyl Glycol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

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- United States: https://lovi.care/skincare/p/wellage/real-hyaluronic-blue-100-ampoule/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/wellage/real-hyaluronic-blue-100-ampoule/for/mature-skin (this page)
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