VT Pro Cica Centella Asiatica Tiger Skin for skin with dark spots

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What the research says

• Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing.

  Journal of Alternative and Complementary Medicine, 2020

• Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements.

  Indian Journal of Pharmaceutical Sciences, 2016

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components.

  Molecules, 2023

• The novel high-payload nanosuspension system of Centella asiatica extract increased skin accumulation of asiatic acid, madecassic acid, and asiaticoside by 5-, 4-, and 4.5-fold respectively compared to a marketed cream in porcine skin, with no local skin irritation in normal rats.

  International Journal of Nanomedicine, 2021

• Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.

  Journal of Cosmetic Dermatology, 2019

• Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline.

  Experimental Dermatology, 2008

• Treatment with an asiaticoside-containing cream applied twice daily for 12 weeks significantly improved periorbital wrinkles in 65% of 27 female volunteers compared to a vehicle control cream.

  International Journal of Cosmetic Science, 2008

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo.

  Clinical Pharmacology, 2018

• Topical propolis application significantly reduced postoperative pain, hemorrhage, and accelerated wound healing in patients undergoing tonsillectomy compared to a control group.

  Clinical and Experimental Otorhinolaryngology, 2018

• Topical treatment with ethanol propolis extract resulted in complete mycological and clinical cure in 56.25% of patients with onychomycosis, demonstrating non-toxicity and effective antifungal activity against Trichophyton spp. both in vitro and in patients.

  Frontiers in Microbiology, 2018

• Topical application of Low-Peony PDRN enhanced barrier recovery and improved periorbital skin elasticity in human subjects.

  International Journal of Molecular Sciences, 2025

• Topical treatment with a ROS-initiated protective reagent reduced UV-induced DNA damage and DNA repair signaling via TP53 in human skin explants compared to administration of a catalase antioxidant.

  Free Radical Biology & Medicine, 2019

• A topical mixture of polydeoxyribonucleotide, vitamin C, and niacinamide delivered via a microneedling therapy system decreased skin pigmentation and increased skin elasticity by attenuating melanogenesis and the destruction of collagen and elastin fibers in a UV-B-radiated animal model.

  Molecules, 2022

Ingredients

Water, Butylene Glycol, Propanediol, 1,2-Hexanediol, Glycerin, C12-14 Pareth-12, Carbomer, Ethylhexylglycerin, Coptis Japonica Root Extract, Disodium Edta, Sodium Hyaluronate, Theobroma Cacao Seed Extract, Hydrolyzed Hyaluronic Acid, Tromethamine, Glyceryl Glucoside, Dextrin, Celery Extract, Prunus Avium Fruit Extract, Pogostemon Cablin Oil, Jojoba Seed Oil, Bitter Almond Kernel Oil, Dna, Agrimonia Eupatoria Extract, Camellia Sinensis Leaf Extract, Hydrogenated Lecithin, Artemisia Vulgaris Oil, Beta-Sitosterol, Pyrus Malus Leaf Extract, Polyquaternium-51, Jasmine Flower Water, Vanilla Planifolia Fruit Extract, Magnolia Kobus Bark Extract, Lonicera Caprifolium Flower Extract Honeysuckle Flower Extract, Pelargonium Graveolens Extract, Uncaria Tomentosa Bark Extract, Corydalis Turtschaninovii Root Extract, Cupressus Sempervirens Leaf Extract, Nepeta Cataria Extract, Capryloyl Salicylic Acid, Lactobionic Acid, Asiaticoside, Madecassoside, Asiatic Acid, Ceramide Np, Madecassic Acid, Propolis Extract

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.