# The Ordinary Retinol 1% in Squalane for acne-prone skin

**Lovi Fit: Average fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/uk/p/the-ordinary/retinol-1-in-squalane/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [The Ordinary](https://lovi.care/skincare/uk/brands/the-ordinary)
Category: [Serums and treatments](https://lovi.care/skincare/uk/best/serums)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for acne-prone skin; other serums fit it better.

## Why this fit

- Offers good suitability for your combination skin due to retinol's desquamation regulation and squalane's emollient action, which also provides general hydration and antioxidant benefits. Rosemary leaf extract supports these effects, though these ingredients are not specifically targeted for your acne, blemishes, and breakouts.
- The formulation is safe for your acne-prone skin as it lacks prohibited or harsh ingredients, minimizing irritation risks.
- It provides a moderate anti-aging visible effect, aiding in minimizing fine lines and wrinkles.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/the-ordinary/retinol-1-in-squalane/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/uk/p/the-ordinary/retinol-1-in-squalane/for/dry-skin): Caution
- [Combination skin](https://lovi.care/skincare/uk/p/the-ordinary/retinol-1-in-squalane/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/uk/p/the-ordinary/retinol-1-in-squalane/for/sensitive-skin): Low
- [Acne-prone skin](https://lovi.care/skincare/uk/p/the-ordinary/retinol-1-in-squalane/for/acne-prone-skin): Average (this page)
- [Skin with dark spots](https://lovi.care/skincare/uk/p/the-ordinary/retinol-1-in-squalane/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/uk/p/the-ordinary/retinol-1-in-squalane/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/the-ordinary/retinol-1-in-squalane/for/dry-sensitive-skin): Caution
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/the-ordinary/retinol-1-in-squalane/for/oily-acne-prone-skin): Average

## Key ingredients

Retinol, Squalane, Solanum Lycopersicum Fruit Extract Tomato Fruit Extract, Jojoba Seed Oil, Bht

## What the research says

- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- Clay jojoba oil facial masks reduced total skin lesions by a mean of 54% after 6 weeks in 133 participants with acne-prone, lesioned skin and mild acne compared to baseline. ([Forschende Komplementarmedizin, 2012](https://pubmed.ncbi.nlm.nih.gov/22585103/))
- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle. ([Archives of Dermatological Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28247017/))
- Topical application of all-trans-retinol induced epidermal thickening and increased retinoid binding protein expression similar to all-trans-retinoic acid in normal human skin, but without causing significant erythema or measurable retinoic acid levels. ([The Journal of Investigative Dermatology, 1995](https://pubmed.ncbi.nlm.nih.gov/7561157/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- Topical lycopene-based emulgel significantly enhanced skin hydration and elasticity while reducing erythema, melanin, and sebum contents in human volunteers compared to a placebo formulation over 12 weeks. ([European Journal of Pharmaceutics and Biopharmaceutics, 2022](https://pubmed.ncbi.nlm.nih.gov/36283632/))
- Cosmetic formulations containing lycopene and melatonin showed significant differences in skin sebum content, hydration, elasticity, erythema index, and melanin index compared to control in 36 healthy women. ([Skin Pharmacology and Physiology, 2020](https://pubmed.ncbi.nlm.nih.gov/33070140/))
- Topical delivery of lycopene via MG- and TG-containing microemulsions significantly increased stratum corneum and viable skin layer penetration compared to a control solution, with the MG-containing microemulsion also increasing skin antioxidant activity by 10-fold. ([Journal of Pharmaceutical Sciences, 2010](https://pubmed.ncbi.nlm.nih.gov/19798758/))
- Topical application of jojoba wax reduced LPS-induced secretion of IL-6, IL-8, and TNFα by approximately 30% and increased the synthesis of pro-collagen III and hyaluronic acid compared to untreated skin in an ex-vivo human skin organ culture model. ([Frontiers in Pharmacology, 2024](https://pubmed.ncbi.nlm.nih.gov/38344180/))
- Topical jojoba oil application in male mice decreased exercise-induced pro-inflammatory gene expression (Il-1b and Il-6 in soleus, Il-1b in gastrocnemius) compared to untreated exercised mice. ([Biomolecules, 2025](https://pubmed.ncbi.nlm.nih.gov/41154623/))
- Nanolipidgel formulations with argan or jojoba oil and humectants demonstrate good sensory attributes, instrumental properties, and moisturizing efficacy for cosmetic application. ([International Journal of Cosmetic Science, 2014](https://pubmed.ncbi.nlm.nih.gov/24772476/))

## Why other serums fit acne-prone skin better

- Topical nicotinamide plus an antibacterial adhesive agent and zinc-pyrrolidone carboxylic acid combined with adapalene significantly reduced noninflammatory acne lesions by the second week of therapy compared to placebo with adapalene in patients with moderate acne vulgaris. ([The Journal of Clinical and Aesthetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32983333/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))

## What reviewers say

This water-free serum is widely praised by users with dry or mature skin for its ability to deeply hydrate while delivering potent anti-aging benefits, such as reduced fine lines and smoother texture. Its oil-based squalane formula is frequently described as heavy or greasy, making it a polarizing choice for those with oily or acne-prone skin who often struggle with absorption.

- Liked: Highly affordable (mostly mentioned)
- Disliked: Greasy/oily finish (mostly mentioned)
- Liked: Improves skin texture (often mentioned)
- Liked: Moisturizing base (often mentioned)
- Liked: Effective anti-aging (sometimes noted)
- Disliked: Irritation & sensitivity (sometimes noted)
- Disliked: Short shelf life (rarely noted)
- Disliked: Unpleasant scent (rarely noted)

## How to apply

- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does The Ordinary Retinol 1% in Squalane work for acne-prone skin?

This treatment works for acne-prone skin, though other products fit it better because they target acne and breakouts directly with ingredients like niacinamide, zinc PCA, and propolis while keeping skin balanced and hydrated.

### Which ingredients make this serum a good fit for acne-prone skin?

Retinol and squalane make this serum a fit by helping renew the skin surface and keeping it soft, though acne-prone skin needs products with ingredients like niacinamide and zinc PCA to better target breakouts.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/)

### What does Retinol do for acne-prone skin?

Retinol helps acne-prone skin by speeding up cell turnover and clearing pores to reduce breakouts. It regulates skin growth and fights inflammation, though it may cause some mild peeling or stinging when you first start using it.
Sources: [Journal of Drugs in Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35816067/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/28318351/)

### What does Squalane do for acne-prone skin?

Squalane may help keep acne-prone skin soft and smooth, but peroxidated forms can trigger inflammation in skin cells. For a better fit on acne-prone skin, products need non-clogging, soothing ingredients that balance oil without causing irritation.
Sources: [The Journal of Investigative Dermatology, 2006](https://pubmed.ncbi.nlm.nih.gov/16778793/)

### Where does this serum go in a skincare routine for acne-prone skin?

This treatment goes in the evening routine after cleansing and before your moisturizer. It is unlikely to irritate your acne-prone skin, though this skin type needs targeted ingredients like salicylic acid or benzoyl peroxide to directly clear blemishes and breakouts.

### Can I use this serum with vitamin C, and in what order?

You can use this treatment and vitamin C in the same routine by applying vitamin C first in the morning and saving this treatment for the evening. Since this treatment is not specifically targeted for your acne, acne-prone skin needs products with ingredients focused on clearing blemishes and soothing inflammation.

### How often should I use this serum?

You can use this treatment serum in your evening routine, starting slowly to see how your skin reacts since it is not specifically targeted for acne breakouts. This type of skin needs targeted ingredients like salicylic acid or benzoyl peroxide to directly clear blemishes and prevent new breakouts.
Sources: [Acta Dermato-venereologica, 2001](https://pubmed.ncbi.nlm.nih.gov/11411906/), [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/)

### Can this serum clog pores, cause breakouts or purging for acne-prone skin?

This product works for your acne-prone skin, though other treatments fit it better. It may cause breakouts or purging because it contains retinol, and a product for this skin needs to feature targeted blemish-clearing ingredients and a lightweight, oil-free feel.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/uk/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/acne-prone-skin) — Superior fit — £36.96 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/uk/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/acne-prone-skin) — Superior fit — £24.20 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/uk/p/skinceuticals/c-e-ferulic/for/acne-prone-skin) — Superior fit — £143.35 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/uk/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — £8.13 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/uk/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — £13.98 at Amazon
- Moisturizer: [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/uk/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — £11.90 at Amazon

## Where to buy

- Amazon.co.uk: £7.20 (https://www.amazon.co.uk/dp/B0779YGB2G?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: £9.00 (https://www.lookfantastic.com/p/the-ordinary-retinol-serum-1-percentage-in-squalane-30ml/11638503/)
Prices checked 15 Oct – 6 Nov 2026.

## Ingredients

Squalane, Caprylic Capric Triglyceride, Retinol, Solanum Lycopersicum Fruit Extract Tomato Fruit Extract, Jojoba Seed Oil, Bht, Hydroxymethoxyphenyl Decanone, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/the-ordinary/retinol-1-in-squalane/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/the-ordinary/retinol-1-in-squalane/for/acne-prone-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/the-ordinary/retinol-1-in-squalane/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/the-ordinary/retinol-1-in-squalane/for/acne-prone-skin
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