# SU:M37 Losec Summa Elixir Night Ampoule for acne-prone skin

**Lovi Fit: Average fit for acne-prone skin.**
Combination Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/uk/p/su-m37/losec-summa-elixir-night-ampoule/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [SU:M37](https://lovi.care/skincare/uk/brands/su-m37)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/uk/best/moisturizers)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for acne-prone skin; other moisturizers fit it better.

## Why this fit

- Offers excellent moisturizing treatment for your combination skin due to the presence of glycerin and panthenol, which hydrate and enhance barrier resilience.
- While it provides general skincare benefits, these are mostly supportive and not directly targeted at your acne, blemishes, and breakouts.
- The formulation is safe for your combination skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/su-m37/losec-summa-elixir-night-ampoule/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/uk/p/su-m37/losec-summa-elixir-night-ampoule/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/uk/p/su-m37/losec-summa-elixir-night-ampoule/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/uk/p/su-m37/losec-summa-elixir-night-ampoule/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/uk/p/su-m37/losec-summa-elixir-night-ampoule/for/acne-prone-skin): Average (this page)
- [Skin with dark spots](https://lovi.care/skincare/uk/p/su-m37/losec-summa-elixir-night-ampoule/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/uk/p/su-m37/losec-summa-elixir-night-ampoule/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/su-m37/losec-summa-elixir-night-ampoule/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/su-m37/losec-summa-elixir-night-ampoule/for/oily-acne-prone-skin): Average

## Key ingredients

Lactobacillus Soybean Extract Ferment, Panthenol, Gold, Wine Extract, Beta-Glucan

## What the research says

- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- ANT1 soybean extract cream ameliorated complications and enhanced skin recovery after Nd:YAG laser therapy in 45 Asian women, with higher concentrations significantly reducing wrinkles, spots, and pores compared to placebo. ([Annals of Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29369914/))
- Genistein and daidzein inhibited UVB-induced hydrogen peroxide production in keratinocytes acting as free radical scavengers with negligible skin disruption, whereas glycitein showed no protective activity. ([International Journal of Pharmaceutics, 2008](https://pubmed.ncbi.nlm.nih.gov/18761396/))
- A phytoestrogen-enriched cosmetic formulation containing biotransformed soybean extract increased collagen-I expression in fibroblast cells and skin explants in an estrogen receptor beta-dependent manner without harming skin microbiota. ([Brazilian Journal of Medical and Biological Research = Revista Brasileira de Pesquisas Medicas E Biologicas, 2023](https://pubmed.ncbi.nlm.nih.gov/37878883/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))
- Topically delivered gold-coated silica microparticles combined with laser pulses reduced inflammatory lesions compared with sham treatments in patients with moderate-to-severe facial acne. ([The Journal of Investigative Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25748556/))
- Laser-activated gold microparticles combined with topical retinoids reduced inflammatory lesion counts by 68% at month 12 in 52 patients with mild-to-moderate inflammatory facial acne. ([Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37943275/))
- Combined treatment with a micro-diamond and micro-gold topical serum and a 1064 nm picosecond Nd:YAG laser produced moderate clinical improvement and high participant satisfaction in 40% of participants for facial skin rejuvenation with minimal side effects. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/35304935/))
- Treatment with Jacquez grapes wine extract protected a three-dimensional tissue culture model of human epidermis against UVB-induced oxidative damage by preventing ROS-mediated alterations. ([Toxicology in Vitro, 2006](https://pubmed.ncbi.nlm.nih.gov/16901675/))
- The V. vinifera skin extract (ACH37) scavenged reactive oxygen species, prevented inflammation, modulated extracellular matrix remodeling, increased telomere length and telomerase activity, and reversed UV-induced gene suppression in in vitro and ex vivo assays. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37464908/))
- Skin care regimens containing beta-glucan improved hemoglobin index, skin hydration, and transepidermal water loss compared to vehicle control in 20 patients undergoing fractional laser therapy. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/))
- Treatment with topical formulations containing beta-glucan combined with nanofractional radiofrequency plus magnetic nanofractional radiofrequency showed the best efficacy and was tolerable and effective in Chinese women with abdominal stretch marks compared to control groups. ([Dermatology and Therapy, 2023](https://pubmed.ncbi.nlm.nih.gov/37171578/))
- Topical beta-glucan mildly improved striae gravidarum, 1565-nm non-ablative fractional laser showed better results than topical beta-glucan, and the combined strategy further improved striae gravidarum atrophy compared to single treatment. ([The Journal of Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35570397/))

## Why other moisturizers fit acne-prone skin better

- Gluconolactone 14% solution significantly improved mild to moderate acne by reducing inflamed and non-inflamed lesions similarly to 5% benzoyl peroxide, but with fewer side-effects in 150 patients. ([The Australasian Journal of Dermatology, 1992](https://pubmed.ncbi.nlm.nih.gov/1303072/))

## What reviewers say

Based on limited data, this night ampoule is highly rated for providing intensive hydration and a radiant glow, particularly for dry or mature skin. Users appreciate its luxurious texture and skin barrier repair benefits. However, the high price point and the presence of essential oils and alcohol are noted concerns, with some experiencing a heavy finish or availability issues.

- Liked: Intensive hydration (mostly mentioned)
- Liked: Radiance and glow (often mentioned)
- Disliked: High price point (often mentioned)
- Liked: Luxurious texture (sometimes noted)
- Liked: Skin barrier repair (sometimes noted)
- Disliked: Availability issues (sometimes noted)
- Disliked: Potential irritants (sometimes noted)
- Disliked: Heavy/sticky finish (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does SU:M37 Losec Summa Elixir Night Ampoule work for acne-prone skin?

SU:M37 Losec Summa Elixir Night Ampoule works moderately well for acne-prone skin, providing general hydration and barrier support with no irritation risk, though its benefits are mostly supportive rather than directly targeting breakouts. To fit acne-prone skin best, a product of this type needs effective ingredients like Niacinamide, Hydrolyzed Hyaluronic Acid, peptides, and Centella Asiatica that address acne and blemishes while providing optimal moisture without excess oiliness.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Which ingredients make this ampoule a good fit for acne-prone skin?

This ampoule works for acne-prone skin because it contains glycerin and panthenol, which hydrate the skin and support the skin barrier. However, a product of this type needs ingredients like Niacinamide, Hydrolyzed Hyaluronic Acid, peptides, and Centella Asiatica to directly target breakouts and provide optimal benefits for this skin type.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### What does Lactobacillus Soybean Extract Ferment do for acne-prone skin?

Lactobacillus Soybean Extract Ferment helps balance the skin microbiome to calm breakouts and keep acne-prone skin clear. Because probiotic and fermented ingredients are generally well-tolerated, this extract is unlikely to cause irritation while supporting smoother skin.
Sources: [Clinical and Experimental Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40679396/)

### What does Panthenol do for acne-prone skin?

Panthenol helps acne-prone skin by soothing redness and supporting the skin barrier while keeping skin hydrated. It is unlikely to cause irritation and works well to calm angry spots without clogging pores.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/)

### Where does it go in a skincare routine for acne-prone skin?

This moisturizing treatment goes in your evening routine after cleansing and before moisturizing. Because it offers supportive benefits rather than targeted care for breakouts, acne-prone skin needs a product of this type to include targeted blemish-fighting ingredients alongside deep hydration.

### Can I use this ampoule with retinol, and in what order?

You can use this treatment alongside retinol by applying the retinol first, letting it dry, and then smoothing on the treatment to help soothe the skin and keep it hydrated. This type of product works best for acne-prone skin when it includes ingredients that clear pores and calm breakouts.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### How often should I use it?

You can use this treatment in the evening as part of your nightly routine. Because this product is not directly targeted at blemishes, acne-prone skin needs a treatment with targeted anti-blemish and clarifying ingredients like salicylic acid or benzoyl peroxide for best results.

### Can it clog pores, cause breakouts or purging for acne-prone skin?

This moisturizing treatment works for acne-prone skin, though other products fit it better because its benefits are mostly supportive rather than directly targeting breakouts. An acne-prone skin needs ingredients and benefits that specifically target blemishes, regulate oil, and clear pores.

### Can I use this ampoule around the eyes or on my body?

You can use this moisturizing treatment around your eyes and on your body, as its safe formula is unlikely to cause irritation. To properly fit acne-prone skin, a product of this type needs targeted blemish-fighting ingredients alongside soothing agents like glycerin and panthenol to keep the skin clear and calm.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Is it fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (alcohol denat).

## Alternatives for acne-prone skin

- [MEDI-PEEL Peptide 9 Volume White Cica All-in-one Essence](https://lovi.care/skincare/uk/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/acne-prone-skin) — High fit — £24.31 at Amazon
- [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/uk/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/acne-prone-skin) — High fit — £34.00 at Amazon
- [MISSHA Super Aqua Ultra Hyalron Ampoule](https://lovi.care/skincare/uk/p/missha/super-aqua-ultra-hyalron-ampoule/for/acne-prone-skin) — Average fit — £18.17 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/uk/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — £8.13 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/uk/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — £13.98 at Amazon
- SPF: [d'Alba Piedmont Waterfull Mild Sunscreen](https://lovi.care/skincare/uk/p/d-alba/piedmont-waterfull-mild-sunscreen/for/acne-prone-skin) — Superior fit — £14.00 at Amazon

## Where to buy

No store in United Kingdom has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Propanediol, Alcohol Denat, 1,2-Hexanediol, Butylene Glycol, Lactobacillus Soybean Extract Ferment, Chondrus Crispus Extract, Bis-Peg-18 Methyl Ether Dimethyl Silane, Panthenol, Peg-40 Hydrogenated Castor Oil, Saccharomyces Barley Seed Ferment Filtrate, Saccharomyces Potato Extract Ferment Filtrate, Lauryl Dimethicone Polyglycerin-3 Crosspolymer, Polymethylsilsesquioxane, Tromethamine, Glyceryl Acrylate Acrylic Acid Copolymer, Wine Extract, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Carbomer, Polyquaternium-51, Gold, Euterpe Oleracea Fruit Extract, Vinegar, Bergamot Oil Fruit, Sodium Polyacrylate, Adenosine, Blueberry Fruit Extract, Lactobacillus Pear Juice Ferment Filtrate, Grapefruit Peel Oil, Lactobacillus Wasabia Japonica Extract Root Ferment, Saccharomyces Grape Extract Ferment, Lactobacillus Water Hyacinth Ferment, Lactobacillus Ginseng Root Ferment Filtrate, Lactobacillus Rye Flour Ferment, Saccharomyces Xylinum Black Tea Ferment, Monascus Rice Ferment, Trisodium Edta, Carthamus Tinctorius Flower Extract, Rosa Damascena Oil Flower, Phyllanthus Emblica Fruit Extract, Artemisia Annua Extract, Neem Leaf Extract, Beta-Glucan, Camellia Sinensis Leaf Extract, Elettaria Cardamomum Seed Oil, Cananga Odorata Oil Flower, Lavandula Angustifolia Oil Lavender Oil, Caprylic Capric Triglyceride, Pogostemon Cablin Oil, Salvia Officinalis Leaf Extract, Zingiber Officinale Root Extract, Clove Flower Extract, Yeast Extract Ferment, Lactobacillus Punica Granatum Extract Fruit Ferment, Diospyros Kaki Fruit Extract, Cucumis Sativus Fruit Extract, Melissa Officinalis Extract, Brassica Oleracea Capitata Leaf Extract, Rehmannia Glutinosa Root Extract, Morus Bombycis Leaf Extract, Ficus Carica Fruit Extract, Perilla Frutescens Leaf Extract, Geranium Robertianum Extract, Ipomoea Batatas Root Extract, Acorus Calamus Root Extract, Undaria Pinnatifida Extract, Pyrus Malus Fruit Extract, Leuconostoc Radish Root Extract, Fraxinus Excelsior Leaf Extract, Brassica Rapa Leaf Extract Turnip Leaf Extract, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Nelumbo Nucifera Root Extract, Thymus Vulgaris Leaf Extract, Onion Bulb Extract, Portulaca Oleracea Extract, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Codonopsis Lanceolata Root Extract, Ginkgo Biloba Nut Extract, Lavandula Angustifolia Flower Extract Lavender Flower Extract, Sesamum Indicum Seed Extract, Citrus Unshiu Peel Extract, Grifola Frondosa Fruiting Body Extract, Fennel Fruit Extract, Daucus Carota Sativa Root Extract Carrot Root Extract, Parsley Extract, Platycodon Grandiflorum Root Extract, Watermelon Fruit Extract, Lonicera Japonica Flower Extract Honeysuckle Flower Extract, Eriobotrya Japonica Leaf Extract, Houttuynia Cordata Extract, Ocimum Basilicum Leaf Extract, Artemisia Princeps Leaf Extract, Panicum Miliaceum Seed Extract, Sasa Veitchii Leaf Extract, Acer Palmatum Leaf Extract, Glechoma Hederacea Extract, Schizonepeta Tenuifolia Extract, Chamomilla Recutita Flower Extract Matricaria Flower Extract, Anemarrhena Asphodeloides Root Extract, Equisetum Arvense Extract, Spinach Leaf Extract, Cassia Obtusifolia Seed Extract, Centella Asiatica Extract, Dandelion Leaf Extract, Camellia Japonica Leaf Extract, Trichosanthes Kirilowii Root Extract, Lycium Chinense Fruit Extract, Allium Sativum Bulb Extract, Illicium Verum Fruit Extract Anise Fruit Extract, Prunus Armeniaca Fruit Extract Apricot Fruit Extract, Citrus Junos Fruit Extract, Beta Vulgaris Root Extract, Musa Sapientum Fruit Extract, Rubus Idaeus Fruit Extract Raspberry Fruit Extract, Carica Papaya Fruit Extract, Phaseolus Angularis Seed Extract, Hemerocallis Fulva Flower Extract, Hypericum Perforatum Stem Extract Flower Leaf, Curcuma Longa Root Extract, Coriandrum Sativum Leaf Extract Fruit, Helianthus Annuus Seed Extract Sunflower Seed Extract, Nigella Sativa Seed Extract, Lentinus Edodes Extract, Cymbopogon Citratus Extract, Plantago Major Seed Extract, Marrubium Vulgare Extract, Cichorium Intybus Root Extract, Prunus Persica Fruit Extract, Peppermint Stem Extract Flower Leaf, Chaenomeles Sinensis Fruit Extract, Bergamot Leaf Extract, Lippia Citriodora Leaf Extract, Akebia Quinata Extract, Crataegus Cuneata Fruit Extract, Actinidia Polygama Fruit Extract, Prunus Salicina Fruit Extract, Jasminum Sambac Flower Extract Jasmine Flower Extract, Citrus Aurantium Dulcis Oil Flower, Cinnamomum Zeylanicum Bark Extract, Valeriana Officinalis Root Extract Rhizome, Honey Extract, Boswellia Serrata Extract Resin
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

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