# SkinMedica TNS Advanced+ Serum for oily skin

**Lovi Fit: Average fit for oily skin.**
Oily Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/uk/p/skinmedica/tns-advanced-serum/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [SkinMedica](https://lovi.care/skincare/uk/brands/skinmedica)
Category: [Serums and treatments](https://lovi.care/skincare/uk/best/serums)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily skin; other serums fit it better.

## Why this fit

- Offers moderate benefits for your oily skin, as Lactococcus Lysate Ferment and Whey Protein support barrier repair, while Human Fibroblast Conditioned Media and Trifluoroacetyl Tripeptide-2 work to smooth texture and minimize fine lines.
- While the serum provides general hydration and soothing effects, it lacks targeted ingredients to address your primary concern of oily shine.
- The product is safe for your oily skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/skinmedica/tns-advanced-serum/for/oily-skin): Average (this page)
- [Dry skin](https://lovi.care/skincare/uk/p/skinmedica/tns-advanced-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/uk/p/skinmedica/tns-advanced-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/uk/p/skinmedica/tns-advanced-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/uk/p/skinmedica/tns-advanced-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/uk/p/skinmedica/tns-advanced-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/uk/p/skinmedica/tns-advanced-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/skinmedica/tns-advanced-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/skinmedica/tns-advanced-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Human Fibroblast Conditioned Media, Collagen Peptides, Trifluoroacetyl Tripeptide-2, Glycerin, Vitis Vinifera Flower Cell Extract Grape Flower Cell Extract

## What the research says

- Topical application of human fibroblast conditioned media and its derived growth factors and exosomes significantly reduces signs of skin aging and stimulates skin recovery and quality after in-office cosmetic procedures. ([Dermatologic Surgery, 2024](https://pubmed.ncbi.nlm.nih.gov/39480036/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A liquid formulation containing hydrolyzed collagen demonstrated structural stability, peptide mass distribution between 0.5 and 19.5 kDa, and faded forehead wrinkles in five volunteers while proving to be non-irritating and hypoallergenic. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/32390321/))
- Exposure to collagen peptides increased the expression of COL1A1, ELN, and VCAN genes and collagen protein levels in cultured human dermal fibroblasts compared to untreated controls. ([Frontiers in Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38751975/))
- Salmo salar and Tilapia nilotica skin collagen peptides accelerate wound healing in a rat murine wound model by reducing proinflammatory cytokines, upregulating BD14, NOD2, IL-10, VEGF, and beta-FGF, and favorably altering wound microflora colonization compared to untreated controls. ([Journal of Agricultural and Food Chemistry, 2020](https://pubmed.ncbi.nlm.nih.gov/31967468/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))

## Why other serums fit oily skin better

- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))
- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))

## What reviewers say

Based on a very large amount of data, this serum is highly praised for its potent anti-aging benefits, specifically targeting coarse wrinkles, fine lines, and sagging skin to produce a firmer, more radiant complexion. Users frequently report visible improvements in skin texture and elasticity. However, the product's high price tag and recurring issues with its dual-chamber pump packaging are common points of frustration.

- Liked: Improves fine lines (mostly mentioned)
- Disliked: Very expensive price (mostly mentioned)
- Liked: Firms sagging skin (often mentioned)
- Liked: Smoothes skin texture (often mentioned)
- Disliked: Faulty pump dispenser (often mentioned)
- Liked: Safe for sensitive skin (sometimes noted)
- Disliked: Uneven product dispensing (sometimes noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week and build up to daily use if your skin tolerates it well.
- Apply the serum after cleansing and toning, but right before your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin. Let it absorb ⏱ for a minute before applying the next product.
- Apply the serum on clean and dry skin since your skin is not sensitive and you want to target oily shine. This helps control excess oil throughout the night.
- Avoid the delicate eye area and do a patch test before using the serum for the very first time.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does TNS Advanced+ Serum work for oily skin?

This serum works moderately well for oily skin by smoothing texture and helping repair the skin barrier, though it lacks targeted ingredients to control oily shine. An ideal product for this skin type needs ingredients like niacinamide and zinc PCA to manage excess oil and enlarged pores while keeping the skin comfortable and hydrated.
Sources: [Dermatologic Surgery, 2024](https://pubmed.ncbi.nlm.nih.gov/39480036/)

### Which ingredients make this serum a good fit for oily skin?

Lactococcus Lysate Ferment and Whey Protein help support barrier repair, while Human Fibroblast Conditioned Media and Trifluoroacetyl Tripeptide-2 work to smooth texture and minimize fine lines. Because this serum lacks ingredients that control oil and manage shine, oily skin needs a product that includes sebum-balancing ingredients like niacinamide or zinc PCA alongside light hydrators.
Sources: [Dermatologic Surgery, 2024](https://pubmed.ncbi.nlm.nih.gov/39480036/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Human Fibroblast Conditioned Media do for oily skin?

Human Fibroblast Conditioned Media helps improve skin quality and recovery, making it suitable for oily skin when you want a smoother and more balanced look. It supports skin renewal and may help keep the skin calm and clear.
Sources: [Dermatologic Surgery, 2024](https://pubmed.ncbi.nlm.nih.gov/39480036/)

### What do Collagen Peptides do for oily skin?

Collagen peptides help balance sebum production while improving skin hydration and elasticity. Taking them daily may support overall skin health and help keep your skin looking smooth and firm.
Sources: [Oxidative Medicine and Cellular Longevity, 2016](https://pubmed.ncbi.nlm.nih.gov/26904164/), [Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/26362110/)

### Where does it go in a skincare routine for oily skin?

This treatment goes in your evening routine, as Lovi places serums and ampoules in the PM for simplicity and extra safety around sun exposure. It is safe for oily skin and unlikely to cause irritation, though managing oily shine requires an oil-balancing ingredient.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying your retinol first at night, followed by this treatment to help smooth texture and keep skin calm. This layering routine is generally safe and unlikely to cause irritation as long as your skin tolerates both active ingredients well.

### How often should I use it?

You can use this treatment in the evening as part of your routine. Oily skin needs lightweight oil-controlling ingredients like niacinamide or salicylic acid to help manage excess shine.
Sources: [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/), [Dermatologic Surgery, 2024](https://pubmed.ncbi.nlm.nih.gov/39480036/)

### Can this serum clog pores, cause breakouts or purging for oily skin?

This serum is unlikely to clog pores or cause breakouts on oily skin, as it has a safe profile with no harsh or prohibited ingredients that trigger irritation. However, because it lacks targeted ingredients to control oily shine, an oily skin type needs lightweight oil-absorbing or balancing ingredients to fully manage excess oil.

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/uk/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/oily-skin) — Superior fit — £36.96 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/uk/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/oily-skin) — Superior fit — £24.20 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/uk/p/skinceuticals/c-e-ferulic/for/oily-skin) — High fit — £143.35 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/uk/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — £8.29 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/uk/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — £13.98 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/uk/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-skin) — Superior fit — £14.80 at Amazon

## Where to buy

No store in United Kingdom has a checked price for this product, so the page shows none.

## Ingredients

Water, Pentylene Glycol, Human Fibroblast Conditioned Media, Glycereth-7 Triacetate, Shea Ethyl Esters Butter, Glycerin, Ethoxydiglycol, Lactococcus Lysate Ferment, Whey Protein, Chlorella Vulgaris Extract, Saccharide Isomerate, Trifluoroacetyl Tripeptide-2, Dimer Tripeptide-43, Hydrolyzed Linseed Extract, Vitis Vinifera Flower Cell Extract Grape Flower Cell Extract, Pyrus Malus Fruit Extract, Hydroxyacetophenone, Tocopheryl Acetate, Propanediol, Xanthan Gum, Polyacrylate Crosspolymer-6, Polyacrylate-13, Polyisobutene, Sclerotium Gum, Peg-12 Dimethicone, Lecithin, Pullulan, Butylene Glycol, Sodium Citrate, Polysorbate 20, Aminomethyl Propanol, Dextran, Disodium Edta, Phenoxyethanol, Ethylhexylglycerin
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/skinmedica/tns-advanced-serum/for/oily-skin
- United Kingdom: https://lovi.care/skincare/uk/p/skinmedica/tns-advanced-serum/for/oily-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/skinmedica/tns-advanced-serum/for/oily-skin
- Germany: https://lovi.care/skincare/de/p/skinmedica/tns-advanced-serum/for/oily-skin
- France: https://lovi.care/skincare/fr/p/skinmedica/tns-advanced-serum/for/oily-skin
- Italy: https://lovi.care/skincare/it/p/skinmedica/tns-advanced-serum/for/oily-skin
- Netherlands: https://lovi.care/skincare/nl/p/skinmedica/tns-advanced-serum/for/oily-skin
- Spain: https://lovi.care/skincare/es/p/skinmedica/tns-advanced-serum/for/oily-skin
- Canada: https://lovi.care/skincare/ca/p/skinmedica/tns-advanced-serum/for/oily-skin
- Australia: https://lovi.care/skincare/au/p/skinmedica/tns-advanced-serum/for/oily-skin
- Singapore: https://lovi.care/skincare/sg/p/skinmedica/tns-advanced-serum/for/oily-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/skinmedica/tns-advanced-serum/for/oily-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/skinmedica/tns-advanced-serum/for/oily-skin