SkinCeuticals Phyto Corrective Gel for mature skin

How to apply

Questions and answers

What the research says

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone.

  Dermatologic Therapy, 2022

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Topical herbal treatments including lemon balm, olive leaf extract, propolis, and sage-rhubarb cream reduce pain, swelling, lesion size, and healing time in patients with herpes labialis compared with placebo or acyclovir.

  Journal of Integrative and Complementary Medicine, 2025

• Topical oleuropein formulations reduced erythema, transepidermal water loss, and blood flow by approximately 22%, 35%, and 30% in healthy volunteers with UVB-induced erythema.

  International Journal of Cosmetic Science, 2008

• An oil-in-serum formulation containing olive extract standardized in hydroxytyrosol improved skin barrier function and significantly reduced hyperpigmentation in participants with post-inflammatory hyperpigmentation after 45 days of application.

  AAPS PharmSciTech, 2026

• Topical application of an aqueous gel containing 0.1% w/w naringenin demonstrated in vitro safety, significantly reduced UV-induced stratum corneum lipid peroxidation, and showed in vivo anti-inflammatory efficacy against methyl nicotinate-induced inflammation in human participants compared to a blank gel and untreated area, while chlorogenic acid, apigenin, and kaempferol displayed pro-oxidant profiles.

  Frontiers in Chemistry, 2024

• Topical application of a naringenin-containing formulation protected hairless mice from ultraviolet B-induced skin damage by inhibiting edema, cytokine production, superoxide anion, and lipid hydroperoxides while maintaining antioxidant enzymes and glutathione levels.

  PloS One, 2016

• Encapsulating naringenin, nordihydroguaiaretic acid (NDGA), and kaempferol into nanostructured lipid carriers provided prolonged release, stability, and antioxidant protection against oxidative stress in human keratinocytes, with an NDGA and kaempferol mixture showing synergistic antioxidant effects.

  Pharmaceutics, 2021

• Transgenic cucumber expressing poly-γ-glutamic acid synthesis genes increased water content by 6-14%, reduced water loss by 11-12%, decreased facial wrinkles and roughness by 19.58% and 24.97%, decreased skin melanin by 5.27%, and improved facial elasticity in human skin and zebrafish compared to controls.

  International Journal of Biological Macromolecules, 2024

• Copper Oxide nanoparticles synthesized using cucumber extract exhibited antibacterial, antifungal, UV protection, and reactive-oxygen species inhibition properties with low cellular toxicity and skin-rejuvenating effects when incorporated into skin cream.

  Endocrine, Metabolic & Immune Disorders Drug Targets, 2021

• Topical treatment with Holothuria parva extract gel showed significant wound contraction compared to the negative control in full-thickness wounded rats.

  The International Journal of Lower Extremity Wounds, 2024

Ingredients

Water, Glycerin, Propylene Glycol, Polysorbate 80, Phenoxyethanol, Sodium Benzoate, Sodium Hyaluronate, Hydroxyethylcellulose, Disodium Edta, Olea Europaea Leaf Extract Olive Leaf Extract, Parfum, Benzophenone-4, Butylene Glycol, Grapefruit Fruit Extract, Cucumis Sativus Fruit Extract, Benzyl Benzoate, Thymus Vulgaris Extract, Eucalyptus Globulus Oil Leaf, Benzyl Alcohol, Alpha-Isomethyl Ionone, Ci 19140, Yellow 5, Ci 42090, Blue 1, Linalool, Citronellol, Morus Alba Root Extract

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.