# SkinCeuticals Phloretin CF for dry sensitive skin

**Lovi Fit: Low fit for dry sensitive skin.**
Dry Skin Fit: Low · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/uk/p/skinceuticals/phloretin-cf/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [SkinCeuticals](https://lovi.care/skincare/uk/brands/skinceuticals)
Category: [Serums and treatments](https://lovi.care/skincare/uk/best/serums)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A weak match for dry sensitive skin; the serums alongside fit it better.

## Why this fit

- Offers moderate antioxidant protection for your dry and sensitive skin due to phloretin and ferulic acid, but alcohol denat may cause dryness and a lack of emollient ingredients does not support the skin barrier.
- The formula provides general skincare benefits, but the concentrations of ascorbic acid and ferulic acid are not optimal for addressing your dry or flaky skin concerns.
- The safety profile is good, with no risks of irritation for your dry and sensitive skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/skinceuticals/phloretin-cf/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/uk/p/skinceuticals/phloretin-cf/for/dry-skin): Caution
- [Combination skin](https://lovi.care/skincare/uk/p/skinceuticals/phloretin-cf/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/uk/p/skinceuticals/phloretin-cf/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/uk/p/skinceuticals/phloretin-cf/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/uk/p/skinceuticals/phloretin-cf/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/uk/p/skinceuticals/phloretin-cf/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/skinceuticals/phloretin-cf/for/dry-sensitive-skin): Low (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/skinceuticals/phloretin-cf/for/oily-acne-prone-skin): High

## Key ingredients

Phloretin, Ascorbic Acid, Ferulic Acid

## What the research says

- Pretreatment with a topical antioxidant mixture of vitamin C, ferulic acid, and phloretin attenuated ultraviolet-induced sunburn cell formation, thymine dimer formation, matrix metalloproteinase-9 expression, p53 protein expression, and the suppression of CD1a-expressing Langerhans cells in human skin compared to vehicle control. ([Journal of Cosmetic Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19146606/))
- A topical antioxidant solution of 15% L-ascorbic acid, 1% alpha-tocopherol, and 0.5% ferulic acid provides significant photoprotection against solar-simulated UV radiation in human skin compared to its vehicle. ([Journal of the American Academy of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18603326/))
- Phloretin 3',3-disulfonate attenuated UVB-induced cyclobutane pyrimidine dimer formation, glutathione depletion, apoptosis, and inflammatory mediator release in skin cells by enhancing nucleotide excision repair gene expression. ([International Journal of Molecular Sciences, 2014](https://pubmed.ncbi.nlm.nih.gov/25334063/))
- Phloretin inhibits the growth of acne-related bacteria, attenuates P. acnes-induced inflammatory mediators in vitro, and significantly reduces comedo counts, sebum output, and porphyrin levels in subjects with whiteheads compared to before treatment. ([International Journal of Cosmetic Science, 2016](https://pubmed.ncbi.nlm.nih.gov/26212527/))
- Compound 11c showed potent inhibitory activity against tyrosinase at nanomolar concentrations and reduced melanin content in a UV-induced skin pigmentation guinea pig model. ([Journal of Medicinal Chemistry, 2023](https://pubmed.ncbi.nlm.nih.gov/36940414/))
- An optimized phloretin-based antiacne hydrogel formulation achieved 75% drug release over 120 minutes and strong antimicrobial activity against Staphylococcus epidermidis with an 11 mm inhibition zone, comparable to benzoyl peroxide gel, while showing no skin irritancy. ([Anti-inflammatory & Anti-allergy Agents in Medicinal Chemistry, 2026](https://pubmed.ncbi.nlm.nih.gov/42163615/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Treatment with 14% ferulic acid and 12% l-ascorbic acid significantly reduced pigmentation and erythema while improving hydration and elasticity in 20 women with photoaged skin, with neither acid proving definitively more effective overall though ascorbic acid showed slightly greater skin lightening. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/34877760/))
- Combining fractional microneedle radiofrequency with a topical antioxidant serum significantly reduced wrinkle severity by 29.9% versus 18.0%, increased elasticity by 12.9% versus 2.3%, and improved aesthetic outcomes in 31 participants compared to radiofrequency and placebo. ([The Journal of Dermatological Treatment, 2025](https://pubmed.ncbi.nlm.nih.gov/40464749/))
- Topical ferulic acid-containing formulations effectively reduce skin erythema, hyperpigmentation, and signs of aging in adults compared to baseline or alternative conditions. ([The Journal of Clinical and Aesthetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40538529/))

## Why other serums fit dry sensitive skin better

- A formulation containing glycerol (5%) and xylitol (5%) applied twice daily for 14 days increased skin hydration, filaggrin protein quantity, interdigitation index, and biomechanical properties, and decreased transepidermal water loss compared to untreated and vehicle-treated skin in twelve volunteers with dry skin. ([Acta Dermato-venereologica, 2017](https://pubmed.ncbi.nlm.nih.gov/27349297/))
- In 50 participants with sensitive skin, a Ceramide NP C15-containing emollient improved skin barrier function with a significant reduction in transepidermal water loss and induced modest changes in skin microbiota compared to the vehicle. ([Skin Pharmacology and Physiology, 2026](https://pubmed.ncbi.nlm.nih.gov/41758783/))
- Topical and oral vitamin E exhibited antitumorigenic, photoprotective, and skin barrier stabilizing properties in human skin. ([Molecular Aspects of Medicine, 2007](https://pubmed.ncbi.nlm.nih.gov/17719081/))

## What reviewers say

Based on a very large amount of data, this product is highly regarded for brightening the complexion, evening skin tone, and reducing discoloration such as dark spots and melasma, particularly benefiting those with normal, oily, combination, or acne-prone skin. Many users report achieving smoother, more radiant skin and a decrease in fine lines. However, a significant number of reviews mention the high cost, a strong scent, and occasional issues with stickiness or packaging.

- Liked: Brightens skin (mostly mentioned)
- Liked: Fades discoloration (often mentioned)
- Liked: Lightweight texture (often mentioned)
- Disliked: High price point (often mentioned)
- Liked: Good for oily skin (sometimes noted)
- Disliked: Unpleasant scent (sometimes noted)
- Disliked: Packaging issues (rarely noted)

## How to apply

- Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
- Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
- Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
- Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
- Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### Why is SkinCeuticals Phloretin CF a weak match for dry sensitive skin?

SkinCeuticals Phloretin CF is a weak match because alcohol denat may cause dryness and the formula lacks nourishing ingredients to support the skin barrier. A treatment for dry sensitive skin needs effective hydrating components that provide moisture retention and protect against irritation without any risk of unsuitability.
Sources: [Journal of Cosmetic Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19146606/), [Journal of the American Academy of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18603326/)

### Which ingredients make this serum a poor fit for dry sensitive skin?

Alcohol denat may cause dryness, and the formula lacks nourishing ingredients to support your skin barrier. A treatment for dry sensitive skin needs rich hydrating components, ceramides, and soothing moisturizers to keep skin soft and comfortable.

### What does phloretin do for dry sensitive skin?

Phloretin helps protect dry sensitive skin from sun damage and inflammation while supporting skin cell repair. It is unlikely to irritate when used as directed, helping keep skin calm and smooth.
Sources: [International Journal of Molecular Sciences, 2014](https://pubmed.ncbi.nlm.nih.gov/25334063/)

### What does vitamin C do for dry sensitive skin?

Vitamin C helps brighten skin, smooth out fine lines, and improve elasticity for dry sensitive skin without causing irritation. When formulated properly with soothing and protective ingredients, it may help calm redness and support the skin barrier.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/), [Antioxidants, 2024](https://pubmed.ncbi.nlm.nih.gov/38397772/)

### Where does this serum go in a skincare routine for dry sensitive skin?

This treatment goes in the evening routine after your cleansing and soothing toner steps, followed by a moisturizer to help guard against dryness. Because this product is a weak match for dry sensitive skin, a treatment of this type needs rich, nourishing ingredients that support the skin barrier and keep skin soft.

### Can I use this serum with retinol, and in what order?

This treatment is a weak match for dry sensitive skin because alcohol denat may cause dryness and the formula lacks softening ingredients to support your skin barrier. A product of this type needs soothing antioxidants alongside hydrating ingredients and rich moisturizing oils to keep dry skin calm and comfortable.
Sources: [Journal of Cosmetic Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19146606/), [Journal of the American Academy of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18603326/)

### How often should I use this serum?

This serum is a weak fit for your dry sensitive skin, so a product of this type needs soothing ingredients, extra moisture to support your skin barrier, and a gentler formula without drying alcohol. When you do use it, evening is the best time for simplicity and extra safety around sun exposure, starting just once a week and only using it more often if you tolerate it well and see good results.
Sources: [Journal of Cosmetic Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19146606/), [Journal of the American Academy of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18603326/)

### Can this serum clog pores, cause breakouts or purging for dry sensitive skin?

This serum is unlikely to clog pores, cause breakouts, or lead to purging on dry sensitive skin. A product of this type needs soothing, barrier-supporting ingredients and gentle hydrating agents to truly comfort and nourish this skin.

### Is this serum fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (alcohol denat).

## Alternatives for dry sensitive skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/uk/p/skinceuticals/c-e-ferulic/for/dry-sensitive-skin) — Superior fit — £143.35 at Amazon
- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/uk/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/dry-sensitive-skin) — Superior fit — £36.96 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/uk/p/augustinus-bader/the-serum/for/dry-sensitive-skin) — Superior fit — £248.00 at Amazon

## Routine for dry sensitive skin

### AM

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/uk/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — £8.29 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/uk/p/clarins/soothing-toning-lotion/for/dry-sensitive-skin) — Superior fit — £17.91 at Amazon
- Moisturizer with Sun Protection: [Real Barrier Mild Sun Cream](https://lovi.care/skincare/uk/p/real-barrier/mild-sun-cream/for/dry-sensitive-skin) — Superior fit — £19.01 at Amazon

### PM

- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/uk/p/missha/ultra-hyalon-cleansing-cream/for/dry-sensitive-skin) — Superior fit — £13.58 at Amazon
- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/uk/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — £8.29 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/uk/p/clarins/soothing-toning-lotion/for/dry-sensitive-skin) — Superior fit — £17.91 at Amazon
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/uk/p/peach-and-lily/glass-skin-refining-serum/for/dry-sensitive-skin) — Superior fit — £59.74 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/uk/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/dry-sensitive-skin) — Superior fit — £38.50 at Amazon

### Weekly

- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/uk/p/missha/ultra-hyalon-cleansing-cream/for/dry-sensitive-skin) — Superior fit — £13.58 at Amazon
- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/uk/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — £8.29 at Amazon
- Enzyme Powder: [Fancl Facial Washing Powder](https://lovi.care/skincare/uk/p/fancl/facial-washing-powder/for/dry-sensitive-skin) — Superior fit — £22.24 at Amazon
- Nourishing Mask: [MEDIHEAL Vita Essential Mask](https://lovi.care/skincare/uk/p/mediheal/vita-essential-mask/for/dry-sensitive-skin) — Superior fit — £17.00 at Amazon
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/uk/p/peach-and-lily/glass-skin-refining-serum/for/dry-sensitive-skin) — Superior fit — £59.74 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/uk/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/dry-sensitive-skin) — Superior fit — £38.50 at Amazon

## Where to buy

- Amazon.co.uk: £134.38 (https://www.amazon.co.uk/dp/B0H228X6CQ?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: £169.00 (https://www.lookfantastic.com/p/skinceuticals-phloretin-cf-antioxidant-serum-for-normal-combination-discolouration-prone-skin-types/11705728/)
Prices checked 10 Oct – 2 Nov 2026.

## Ingredients

Water, Dipropylene Glycol, Alcohol Denat, Ascorbic Acid, Butylene Glycol, Triethyl Citrate, Phloretin, Ferulic Acid
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/skinceuticals/phloretin-cf/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/skinceuticals/phloretin-cf/for/dry-sensitive-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/skinceuticals/phloretin-cf/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/skinceuticals/phloretin-cf/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/skinceuticals/phloretin-cf/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/skinceuticals/phloretin-cf/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/skinceuticals/phloretin-cf/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/skinceuticals/phloretin-cf/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/skinceuticals/phloretin-cf/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/skinceuticals/phloretin-cf/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/skinceuticals/phloretin-cf/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/skinceuticals/phloretin-cf/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/skinceuticals/phloretin-cf/for/dry-sensitive-skin