# SKIN1004 Madagascar Centella Tea-Trica Relief Ampoule for acne-prone skin

**Lovi Fit: High fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/uk/p/skin1004/madagascar-centella-tea-trica-relief-ampoule/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [SKIN1004](https://lovi.care/skincare/uk/brands/skin1004)
Category: [Serums and treatments](https://lovi.care/skincare/uk/best/serums)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for acne-prone skin; a few serums fit it even better.

## Why this fit

- This product offers high suitability for your combination, acne-prone skin as Centella Asiatica Extract and Melaleuca Alternifolia Tree Leaf Water work to soothe inflammation and combat breakouts. Glycerin and Butylene Glycol provide essential hydration without clogging pores, balancing your skin's needs.
- The inclusion of Pinus Palustris Leaf Extract and Chamaecyparis Obtusa Water further supports skin clarity and reduces redness, complementing the primary actives.
- The formulation is safe for your skin, free from harsh ingredients and containing beneficial soothing agents like Centella Asiatica Extract and Melaleuca Alternifolia Oil Leaf.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/skin1004/madagascar-centella-tea-trica-relief-ampoule/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/uk/p/skin1004/madagascar-centella-tea-trica-relief-ampoule/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/uk/p/skin1004/madagascar-centella-tea-trica-relief-ampoule/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/uk/p/skin1004/madagascar-centella-tea-trica-relief-ampoule/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/uk/p/skin1004/madagascar-centella-tea-trica-relief-ampoule/for/acne-prone-skin): High (this page)
- [Skin with dark spots](https://lovi.care/skincare/uk/p/skin1004/madagascar-centella-tea-trica-relief-ampoule/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/uk/p/skin1004/madagascar-centella-tea-trica-relief-ampoule/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/skin1004/madagascar-centella-tea-trica-relief-ampoule/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/skin1004/madagascar-centella-tea-trica-relief-ampoule/for/oily-acne-prone-skin): High

## Key ingredients

Centella Asiatica Extract, Tree Leaf Water, Chamaecyparis Obtusa Water, Oenothera Biennis Flower Extract, Glycerin

## What the research says

- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical 5% tea tree oil gel significantly improved total acne lesions and acne severity index compared to placebo in 60 patients with mild to moderate acne vulgaris, showing 3.55 times and 5.75 times greater efficacy respectively. ([Indian Journal of Dermatology, Venereology and Leprology, 2007](https://pubmed.ncbi.nlm.nih.gov/17314442/))
- Lactobacillus-fermented Chamaecyparis obtusa reduced inflammatory acne lesions by 65.3% compared to 38.2% with tea tree oil in 34 patients over 8 weeks, demonstrating superior efficacy, faster onset, and safety. ([Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25228478/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Hinokitiol treatment attenuates LPS-induced proinflammatory factors, NF-kappaB activation, and cell migration in primary human keratinocytes via Sirt1 histone deacetylase activation. ([The Journal of Investigative Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28257794/))
- A lipid mixture representing major components of Chamaecyparis obtusa extract up-regulated HBD-3 and LL-37, exhibited bactericidal effects against Staphylococcus aureus and Streptococcus pyogenes, protected against keratinocyte cell death, and accelerated skin wound healing and healing of S. aureus-superinfected wounds in an animal model. ([The Journal of Investigative Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29277539/))
- Chamaecyparis obtusa 70% ethanol extract exhibited antioxidant, antiwrinkle, and anti-inflammatory effects in UVA-irradiated fibroblasts by suppressing cell death by 21.3% at 25 µg/mL and increasing collagen type I and superoxide dismutase mRNA levels. ([Medicina, 2023](https://pubmed.ncbi.nlm.nih.gov/37109713/))
- Electrospun poly (vinyl butyral-co-vinyl alcohol-co-vinyl acetate) patches loaded with evening primrose oil applied to the forearm of volunteers for 6 hours increased skin moisture, with pore size, shape, and fiber diameter influencing oil transport. ([Biomaterials Advances, 2022](https://pubmed.ncbi.nlm.nih.gov/35929319/))
- A topical preparation containing urea, sunflower oil, evening primrose oil, wheat germ oil, and sodium pyruvate led to clinical improvement after a month in diverse hyperkeratotic skin conditions except pityriasis lichenoides. ([Medicina Cutanea Ibero-latino-americana, 1986](https://pubmed.ncbi.nlm.nih.gov/3528709/))
- Oenothera biennis cell culture aqueous extract promoted matrix collagen contraction, actin polymerization, and essential extracellular matrix protein production by increasing MYLK gene expression in in vitro, cell, and ex vivo skin aging models. ([Metabolites, 2021](https://pubmed.ncbi.nlm.nih.gov/34436468/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))

## What reviewers say

This ampoule is highly recommended for oily, acne-prone, and sensitive skin types due to its lightweight, fast-absorbing, and non-sticky formula that effectively calms redness and soothes active breakouts. Users with dry skin, however, report that it may not provide adequate hydration and suggest layering with a richer moisturizer.

- Liked: Lightweight texture (mostly mentioned)
- Liked: Soothes redness (mostly mentioned)
- Liked: Controls acne (often mentioned)
- Liked: Gentle on sensitive (sometimes noted)
- Disliked: Not moisturizing enough (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Ineffective for some (rarely noted)
- Disliked: Scent is strong (rarely noted)

## How to apply

- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes SKIN1004 Tea-Trica Relief Ampoule a great fit for acne-prone skin?

This product is a great fit because Centella Asiatica Extract and tea tree leaf water calm redness and help fight breakouts, while glycerin keeps your skin hydrated without clogging pores. Additional plant extracts work together to support skin clarity and soothe irritation safely.
Sources: [Indian Journal of Dermatology, Venereology and Leprology, 2007](https://pubmed.ncbi.nlm.nih.gov/17314442/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### Which ingredients make this serum a good fit for acne-prone skin?

Centella Asiatica Extract and Melaleuca Alternifolia Tree Leaf Water make this serum a great fit by soothing redness and helping fight breakouts. Glycerin and Butylene Glycol also provide light hydration that is unlikely to clog pores.
Sources: [Indian Journal of Dermatology, Venereology and Leprology, 2007](https://pubmed.ncbi.nlm.nih.gov/17314442/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### What does Centella Asiatica Extract do for acne-prone skin?

Centella asiatica extract helps calm angry skin, reduces redness, and supports healing for breakouts. It is unlikely to cause irritation and may improve overall skin clarity when used consistently.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/)

### What does Tree Leaf Water do for acne-prone skin?

Tree leaf water helps calm acne-prone skin by reducing redness and soothing irritated areas. Plant extracts of this type generally need antibacterial ingredients to properly target breakout-causing bacteria.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12452873/), [Pakistan Journal of Pharmaceutical Sciences, 2024](https://pubmed.ncbi.nlm.nih.gov/39495857/)

### Where does this serum go in a skincare routine for acne-prone skin?

This treatment goes in your evening routine after cleansing and toning, and before your moisturizer. Putting it in the evening keeps things simple and safer around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this treatment alongside retinol by applying the treatment first and following with your retinol on alternate nights or spaced out to keep your skin calm. Using a gentle routine helps reduce the irritation that can happen when combining active ingredients.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/), [American Family Physician, 2012](https://pubmed.ncbi.nlm.nih.gov/23062156/)

### How often should I use this serum?

You can use this treatment in the evening as part of your routine. It is a great fit for your acne-prone skin and helps soothe inflammation and combat breakouts without clogging your pores.
Sources: [Indian Journal of Dermatology, Venereology and Leprology, 2007](https://pubmed.ncbi.nlm.nih.gov/17314442/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### Can this serum clog pores, cause breakouts or purging for acne-prone skin?

This product is unlikely to clog pores or cause breakouts because it uses light hydrators that balance acne-prone skin without heavy oils. Its soothing ingredients help calm redness and combat pimples safely.
Sources: [Indian Journal of Dermatology, Venereology and Leprology, 2007](https://pubmed.ncbi.nlm.nih.gov/17314442/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/uk/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/acne-prone-skin) — Superior fit — £36.96 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/uk/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/acne-prone-skin) — Superior fit — £24.20 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/uk/p/skinceuticals/c-e-ferulic/for/acne-prone-skin) — Superior fit — £143.35 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/uk/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — £8.13 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/uk/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — £13.98 at Amazon
- Moisturizer: [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/uk/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — £11.90 at Amazon

## Where to buy

- Amazon.co.uk: £9.85 (https://www.amazon.co.uk/dp/B0DP5X3XRK?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- Notino: £8.30 (https://www.notino.co.uk/skin1004/madagascar-centella-tea-trica-relief-ampoule-soothing-face-serum-for-problematic-skin-acne/p-16304299/)
Prices checked 16 Oct – 6 Nov 2026.

## Ingredients

Centella Asiatica Extract, Chamaecyparis Obtusa Water, Melaleuca Alternifolia Tree Leaf Water, Pinus Palustris Leaf Extract, Glycerin, Butylene Glycol, Methyl Gluceth-20, Dipropylene Glycol, Glycereth-26, 1,2-Hexanediol, Water, Hydroxyacetophenone, Ammonium Acryloyldimethyl Taurate Vp Copolymer, Propanediol, Polyglyceryl-10 Laurate, Ethylhexylglycerin, Pentylene Glycol, Caprylyl Glycol, Disodium Edta, Melaleuca Alternifolia Oil Leaf, Oenothera Biennis Flower Extract, Pueraria Lobata Root Extract, Ulmus Davidiana Root Extract
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

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