# SK-II Genoptics Ultraura Essence for sensitive skin

**Lovi Fit: High fit for sensitive skin.**
Normal Skin Fit: Superior · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/uk/p/sk-ii/genoptics-ultraura-essence/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [SK-II](https://lovi.care/skincare/uk/brands/sk-ii)
Category: [Serums and treatments](https://lovi.care/skincare/uk/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for sensitive skin.

## Why this fit

- Excellent suitability for your normal skin is provided by Nicotinamide W and L-Ascorbic Acid 2-Glucoside, which offer antioxidant activity and melanogenesis regulation to address your redness and irritation goals.
- The formulation also includes D-Pantothenyl Alcohol for soothing effects, further supporting your skin's needs.
- The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/sk-ii/genoptics-ultraura-essence/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/uk/p/sk-ii/genoptics-ultraura-essence/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/uk/p/sk-ii/genoptics-ultraura-essence/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/uk/p/sk-ii/genoptics-ultraura-essence/for/sensitive-skin): High (this page)
- [Acne-prone skin](https://lovi.care/skincare/uk/p/sk-ii/genoptics-ultraura-essence/for/acne-prone-skin): Superior
- [Skin with dark spots](https://lovi.care/skincare/uk/p/sk-ii/genoptics-ultraura-essence/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/uk/p/sk-ii/genoptics-ultraura-essence/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/sk-ii/genoptics-ultraura-essence/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/sk-ii/genoptics-ultraura-essence/for/oily-acne-prone-skin): Superior

## Key ingredients

Nicotinamide W, D-Pantothenyl Alcohol, L-Ascorbic Acid 2-Glucoside, Undecylenoyl Phenylalanine, Sk-Ii Pitera Concentrate

## What the research says

- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Application of Galactomyces ferment filtrate skin care formula significantly reduced the net values and daily fluctuation of facial pore area, roughness, and redness in young Japanese women. ([Journal of Clinical Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34198790/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of ascorbic acid 2-glucoside combined with laser gingival depigmentation reduced pigmentation recurrence and increased patient satisfaction at nine months in 20 participants with physiologic gingival hyperpigmentation compared to laser depigmentation alone. ([Cureus, 2026](https://pubmed.ncbi.nlm.nih.gov/42147661/))
- Ascorbic acid 2-glucoside at 1.8% showed similar protective effects against oxidative stress compared to 15% ascorbic acid in human skin models despite a lower concentration, and demonstrated superior chemical stability. ([International Journal of Cosmetic Science, 2021](https://pubmed.ncbi.nlm.nih.gov/34679221/))
- Topical application of undecylenoyl phenylalanine 2% significantly lightened solar lentigines on the hands compared to vehicle control in 30 patients, with moderate to marked improvement and minimal side-effects. ([Clinical and Experimental Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/19874316/))
- Nanostructured lipid carriers efficiently deliver undecylenoyl phenylalanine into the skin with higher accumulation and sustained release compared to emulsion and ethanol formulations, showing promise for topical treatment of hyperpigmentation. ([Advanced Pharmaceutical Bulletin, 2023](https://pubmed.ncbi.nlm.nih.gov/37342381/))
- Solid lipid nanoparticles containing Undecylenoyl phenylalanine achieved enhanced cutaneous uptake, spherical morphology with a particle size of 218.6 nm, and an entrapment efficiency of 87.31% while successfully inhibiting the tyrosinase enzyme to stop melanogenesis. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35593521/))
- Saccharomycopsis Ferment Filtrate inhibits lipopolysaccharide-induced nitric oxide production and iNOS protein expression in RAW264.7 macrophages and protects artificial epidermis against lipopolysaccharide- or ultraviolet radiation-induced damages. ([Journal of Dermatological Science, 2006](https://pubmed.ncbi.nlm.nih.gov/16533596/))

## What reviewers say

This essence is highly praised for its hydrating and lightweight texture, providing a radiant glow and improving skin texture for normal and combination skin types. While it effectively brightens the complexion, some users note it is less potent for deep hyperpigmentation compared to previous versions. The high price is a significant concern for many.

- Disliked: Very high price (mostly mentioned)
- Liked: Improves radiance (often mentioned)
- Liked: Lightweight texture (often mentioned)
- Liked: Convenient packaging (sometimes noted)
- Liked: Even skin tone (sometimes noted)
- Disliked: Less effective brightening (sometimes noted)
- Disliked: Contains sensitizers (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Genoptics Ultraura Essence a great fit for sensitive skin?

This treatment is a great fit for sensitive skin because it features D-Pantothenyl Alcohol for soothing effects, along with Nicotinamide W and L-Ascorbic Acid 2-Glucoside to help calm redness and irritation. It has an excellent safety profile with no harsh ingredients, making it very gentle on your skin.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/)

### Which ingredients make this serum a good fit for sensitive skin?

Nicotinamide W, L-Ascorbic Acid 2-Glucoside, and D-Pantothenyl Alcohol make this serum a great fit for sensitive skin by helping calm redness and irritation. D-Pantothenyl Alcohol and SK-II Pitera Concentrate further support your skin's needs with soothing effects and a safe profile that is unlikely to cause irritation.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [Journal of Clinical Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34198790/)

### What does Niacinamide do for sensitive skin?

Niacinamide helps calm and soothe sensitive skin by strengthening the skin barrier and reducing redness and irritation. It is generally well tolerated and may improve dryness and overall comfort when used daily.
Sources: [Cutis, 2005](https://pubmed.ncbi.nlm.nih.gov/16209160/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### What does Panthenol do for sensitive skin?

Panthenol helps calm sensitive skin by reducing redness and irritation while improving hydration and repairing the skin barrier. It is unlikely to cause negative reactions and supports healing for dry or reactive skin.
Sources: [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40682399/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Where does this serum go in a skincare routine for sensitive skin?

This treatment goes in the evening routine after cleansing and toning, and before your moisturizer. Putting it in the evening helps keep things simple and safe around sun exposure, and its soothing ingredients make it a very low risk for irritation.

### Can I use this serum with retinol, and in what order?

You can use this treatment alongside retinol, applying this essence before your retinol product to help keep your skin calm. The formula contains soothing ingredients like D-Pantothenyl Alcohol that help prevent irritation.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### How often should I use this serum?

This treatment is used in the evening as part of your routine. The formula is very safe for sensitive skin and is unlikely to cause irritation.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [Journal of Clinical Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34198790/)

### Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum is unlikely to cause breakouts or clog pores for sensitive skin, as it has an excellent safety profile without harsh ingredients. The formula includes soothing components that help keep your skin calm.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/)

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (benzyl alcohol).

## Alternatives for sensitive skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/uk/p/skinceuticals/c-e-ferulic/for/sensitive-skin) — High fit — £143.35 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/uk/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — £25.95 at Amazon
- [COSRX The Vitamin C 23 Serum](https://lovi.care/skincare/uk/p/cosrx/the-vitamin-c-23-serum/for/sensitive-skin) — High fit — £16.11 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/uk/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — £14.99 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/uk/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — £17.91 at Amazon
- Moisturizer with Sun Protection: [Clinique Mineral Sunscreen Fluid for Face SPF 50](https://lovi.care/skincare/uk/p/clinique/broad-spectrum-spf-50-mineral-sunscreen-fluid-for-face/for/sensitive-skin) — Superior fit — £21.00 at Amazon

## Where to buy

- Notino: £217.00 (https://www.notino.co.uk/sk-ii/genoptics-ultraura-essence-brightening-serum/p-16254642/)
Prices checked 5 Nov 2026.

## Ingredients

Nicotinamide W, D-Pantothenyl Alcohol, Sk-Ii Pitera Concentrate, L-Ascorbic Acid 2-Glucoside, Undecylenoyl Phenylalanine, Inosit, Nelumbo Nucifera Extract, Chilicit, Sucrose Fatty Acid Ester, Concentrated Glycerin, Glyceryl Triethylhexanoate, Peg1540, Lauroyl Di Phytosteryl Octyldodecyl Glutamate, Crosslinked Silicone Reticulated Silicone Block Copolymer, Boron Nitride, Titanium Mica, Tri Caprylic Capric Acid Glyceryl, Poe Sorbitan Laurate, Bg, Acrylic Acid Methacryl Acid Alkyl Copolymer, Yellow Fe Oxide, Methylhydrogenpolysiloxane, Polyacrylamide, Plasma-Fluid Isoparaffin, Poe Lauryl Ether, Amp, Xanthan Gum, Benzyl Alcohol, Pentylene Glycol, Phenoxyethanol, Edetate, Benzoin Acid Salts, Parabens, Water
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/sk-ii/genoptics-ultraura-essence/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/sk-ii/genoptics-ultraura-essence/for/sensitive-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/sk-ii/genoptics-ultraura-essence/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/sk-ii/genoptics-ultraura-essence/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/sk-ii/genoptics-ultraura-essence/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/sk-ii/genoptics-ultraura-essence/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/sk-ii/genoptics-ultraura-essence/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/sk-ii/genoptics-ultraura-essence/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/sk-ii/genoptics-ultraura-essence/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/sk-ii/genoptics-ultraura-essence/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/sk-ii/genoptics-ultraura-essence/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/sk-ii/genoptics-ultraura-essence/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/sk-ii/genoptics-ultraura-essence/for/sensitive-skin