Senallis Hyaluronic Acid Serum for oily acne-prone skin
Sodium Hyaluronate
Glycerin
Citric Acid
Phenoxyethanol
Ethylhexylglycerin
Average
- HighOily Skin Fit
- AverageEffectiveness
- ExcellentSafety
Works for oily acne-prone skin; other moisturizers fit it better.
This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate moisturizing for your oily skin due to glycerin and sodium hyaluronate, which provide humectant action and hydration. These ingredients are highly suitable for oily skin, but do not directly address your primary concerns of acne, blemishes, and breakouts.
- The product's functionality is limited as it primarily offers general hydration, which is less relevant for targeting your specific skin issues.
- The safety profile is excellent, with no risks of irritation for your oily skin due to the absence of harsh ingredients and the presence of soothing components like glycerin and sodium hyaluronate.
How to apply
- Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
- Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
- Gently press a small amount into your skin and avoid rubbing to keep pores clear.
- Apply on clean, slightly damp skin to help the product absorb better and control oil.
- Avoid the sensitive eye area and do a simple patch test before your first use.
Questions and answers
How well does Senallis Hyaluronic Acid work for oily acne-prone skin?
Senallis Hyaluronic Acid Serum works moderately well for oily acne-prone skin, as it gives you light moisture with glycerin and sodium hyaluronate without clogging your pores or causing irritation. However, it does not directly target breakouts, blemishes, or your main acne concerns. To fit oily acne-prone skin best, a moisturizing treatment needs ingredients like niacinamide, ceramides, or pro vitamin B5 that hydrate while helping to clear and balance acne-prone skin.
Which ingredients make this serum a good fit for oily acne-prone skin?
Glycerin and sodium hyaluronate make this serum a good fit for oily acne-prone skin by providing light moisture without clogging pores. Because it lacks ingredients to target breakouts and blemishes, a product of this type needs ingredients like niacinamide, ceramides, and soothing plant extracts to truly balance and care for this skin type.
What does Hyaluronic Acid do for oily acne-prone skin?
Hyaluronic acid helps calm oily acne-prone skin by reducing sebum production and lipid synthesis in sebaceous glands. It also supports skin barrier function and improves hydration while helping deliver treatments without causing irritation.
The Journal of Investigative Dermatology, 2017Journal of Cosmetic Dermatology, 2022
What does Glycerin do for oily acne-prone skin?
Glycerin helps keep oily acne-prone skin hydrated without feeling heavy. It draws moisture into the skin while supporting the skin barrier so it stays soft and balanced.
The British Journal of Dermatology, 2008Clinical, Cosmetic and Investigational Dermatology, 2017
Where does this serum go in a skincare routine for oily acne-prone skin?
This serum goes in the evening routine after cleansing and before moisturizing, though it only gives general hydration rather than clearing breakouts. Oily acne-prone skin needs targeted ingredients like niacinamide or blemish-fighting actives to effectively address breakouts.
Can I use this serum with retinol, and in what order?
You can use this serum with retinol by applying the serum first to keep your skin hydrated and calm, followed by your retinol. This product is unlikely to irritate oily skin, but because it only offers general hydration, oily acne-prone skin also needs targeted ingredients that clear blemishes and breakouts.
Cutis, 2006Clinical, Cosmetic and Investigational Dermatology, 2017
How often should I use this serum?
You can use this serum in the evening as part of your routine, and some treatments may also be used in the morning or twice a day. Regular daily application helps improve skin moisture and barrier function.
Health Science Reports, 2021Clinical, Cosmetic and Investigational Dermatology, 2017
Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?
This serum is unlikely to cause breakouts or clog pores on oily skin because it has a very safe formula with no harsh ingredients. It provides basic hydration, but an average fit for acne-prone skin means a product of this type needs extra ingredients that directly target breakouts and blemishes.
Can I use this serum around the eyes or on my body?
You can use this serum on the thin skin around your eyes and on your body, as it has an excellent safety profile with no harsh ingredients that might cause irritation. Its light moisturizing ingredients are suitable for delicate areas, though skin thickness varies across different body regions.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.
Journal of Cosmetic Dermatology, 2020Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.
International Journal of Cosmetic Science, 2001Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.
Journal of Drugs in Dermatology, 2012A novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid showed similar tolerance and efficacy compared with clindamycin 1% and benzoyl peroxide 5% gel in subjects with acne vulgaris.
Journal of Drugs in Dermatology, 2013Daily treatment with a facial serum containing multiple acids reduced post-inflammatory hyperchromia lesion grade and number by 29.4% at 56 days, and decreased skin oiliness by 30.7% at 7 days in Brazilian patients with acne vulgaris.
Journal of Cosmetic Dermatology, 2021Topical 20% citric acid lotion increases viable epidermal thickness and dermal glycosaminoglycan content in sun-damaged skin compared to vehicle alone.
Dermatologic Surgery, 1997
Why other moisturizers fit oily acne-prone skin better
Gluconolactone 14% solution significantly improved mild to moderate acne by reducing inflamed and non-inflamed lesions similarly to 5% benzoyl peroxide, but with fewer side-effects in 150 patients.
The Australasian Journal of Dermatology, 1992A peel-off facial mask containing myoinositol and trehalose-loaded liposomes improved adult female acne by decreasing lesion counts, sebum production, GAGS scores, and local androgen levels while increasing beclin-1 levels.
Journal of Cosmetic Dermatology, 2017Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components.
Molecules, 2023
Ingredients
Distilled Water, Glycerin, Sodium Hyaluronate, Phenoxyethanol, Ethylhexylglycerin, Citric Acid, Potassium Sorbate
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Dr. Sofía Perea Pérez, MD, MSc
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Specialist dermatologist, MBBS, MD, IFAAD
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Elina Nazarenko, MD
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Victoria Derkova, MS
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