# REJURAN Rejuran® Healer Turnover Ampoule for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/uk/p/rejuran/healer-turnover-ampoule/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [REJURAN](https://lovi.care/skincare/uk/brands/rejuran)
Category: [Serums and treatments](https://lovi.care/skincare/uk/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other serums fit it better.

## Why this fit

- Offers moderate suitability for your combination skin as arbutin and niacinamide help regulate melanogenesis and seboregulation, contributing to a more uniform complexion.
- Aloe barbadensis leaf juice and calendula officinalis flower extract provide general hydration and soothing benefits, though they do not specifically target your concern with oily shine.
- The product is safe for your combination skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/rejuran/healer-turnover-ampoule/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/uk/p/rejuran/healer-turnover-ampoule/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/uk/p/rejuran/healer-turnover-ampoule/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/uk/p/rejuran/healer-turnover-ampoule/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/uk/p/rejuran/healer-turnover-ampoule/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/uk/p/rejuran/healer-turnover-ampoule/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/uk/p/rejuran/healer-turnover-ampoule/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/rejuran/healer-turnover-ampoule/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/rejuran/healer-turnover-ampoule/for/oily-acne-prone-skin): Average

## Key ingredients

C-Pdrn

## What the research says

- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- Topical application of Low-Peony PDRN enhanced barrier recovery and improved periorbital skin elasticity in human subjects. ([International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/41516097/))
- Polydeoxyribonucleotide promotes skin regeneration by increasing ERK phosphorylation, collagen accumulation, and cell proliferation and migration in fibroblasts while inhibiting ERK phosphorylation and inflammatory cytokine expression in keratinocytes. ([Molecular Medicine Reports, 2023](https://pubmed.ncbi.nlm.nih.gov/37350391/))
- A topical mixture of polydeoxyribonucleotide, vitamin C, and niacinamide delivered via a microneedling therapy system decreased skin pigmentation and increased skin elasticity by attenuating melanogenesis and the destruction of collagen and elastin fibers in a UV-B-radiated animal model. ([Molecules, 2022](https://pubmed.ncbi.nlm.nih.gov/35209068/))

## Why other serums fit combination skin better

- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))
- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))

## What reviewers say

Users frequently report achieving a radiant "glass skin" appearance and deep hydration with this ampoule, noting significant improvements in skin texture and plumpness. It is often praised for its effectiveness in repairing damaged skin barriers, soothing redness, and aiding in the healing of acne scars. A small number of users with oily skin have found it to be slightly heavy for daytime application.

- Liked: Hydration and glow (mostly mentioned)
- Liked: Absorbs quickly (often mentioned)
- Liked: Smoother texture (often mentioned)
- Disliked: Expensive product (often mentioned)
- Liked: Calms redness (sometimes noted)
- Disliked: Awkward packaging (sometimes noted)
- Disliked: Minor breakouts (rarely noted)
- Disliked: Slightly sticky (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Rejuran Healer Turnover Ampoule work for combination skin?

This treatment works reasonably well for your combination skin because arbutin and niacinamide help even out your complexion while aloe and calendula provide gentle hydration and comfort. However, a treatment for this skin needs ingredients like niacinamide and zinc PCA to better manage oily shine without any risk of imbalance.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### Which ingredients make this serum a good fit for combination skin?

Arbutin and niacinamide make this serum a good fit for your combination skin by helping even out your skin tone. It is safe and unlikely to cause irritation, but combination skin needs ingredients like niacinamide and zinc PCA to properly manage oily shine.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### What does C-Pdrn do for combination skin?

C-Pdrn helps repair skin and calms inflammation to make your skin smoother and more even. It encourages cell renewal and improves hydration without clogging pores, which works well for balancing the different areas of combination skin.
Sources: [Biomolecules, 2025](https://pubmed.ncbi.nlm.nih.gov/39858543/), [Materials Science & Engineering. C, Materials for Biological Applications, 2016](https://pubmed.ncbi.nlm.nih.gov/27612747/)

### Where does this serum go in a skincare routine for combination skin?

This treatment goes in the evening routine after cleansing toner and before moisturizer, as serums and ampoules with actives fit best at night for simplicity and extra safety around sun exposure. Combination skin of this type needs ingredients that regulate oil and provide targeted balancing care to properly address oily shine.

### Can I use this serum with retinol, and in what order?

You can use this treatment alongside retinol by applying the serum first to clean skin and following with your retinol once it absorbs. This product is unlikely to cause irritation on combination skin, but combining active ingredients may require starting slowly to keep your skin calm and smooth.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### How often should I use this serum?

This treatment works well in your evening routine, where it helps even out your skin tone while keeping things calm and safe. Combination skin often benefits most from adding oil-controlling ingredients to manage shiny areas throughout the day.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### Can this serum clog pores, cause breakouts or purging for combination skin?

This serum is safe for your combination skin and is unlikely to cause irritation, though minor breakouts are a negligible possibility. A product for this skin needs ingredients that help balance oily shine while keeping it calm and hydrated.

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (benzyl alcohol).

## Alternatives for combination skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/uk/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/combination-skin) — Superior fit — £36.96 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/uk/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin) — Superior fit — £24.20 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/uk/p/augustinus-bader/the-serum/for/combination-skin) — Superior fit — £248.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/uk/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — £14.99 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/uk/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — £30.37 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/uk/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — £14.80 at Amazon

## Where to buy

- Amazon.co.uk: £44.00 (https://www.amazon.co.uk/dp/B08BZCY3Y1?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Blackberry Leaf Extract, Glycyrrhiza Glabra Callus Culture Extract Licorice Callus Culture Extract, Calendula Officinalis Flower Extract, Aloe Barbadensis Leaf Juice, Blueberry Fruit Extract, Morus Nigra Fruit Extract Morus Alba Fruit Extract, Arbutin, Butylene Glycol, Glycerin, Polysorbate 20, Hydrolyzed Dna, Hyaluronic Acid, Carbomer, Xanthan Gum, Adenosine, Tocopheryl Acetate, Niacinamide, Bisabolol, Peg-6, Phenoxyethanol, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Benzyl Alcohol, 12-Hexanediol, Dipropylene Glycol, Sodium Chloride, Trehalose, Urea
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/rejuran/healer-turnover-ampoule/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/rejuran/healer-turnover-ampoule/for/combination-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/rejuran/healer-turnover-ampoule/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/rejuran/healer-turnover-ampoule/for/combination-skin
- France: https://lovi.care/skincare/fr/p/rejuran/healer-turnover-ampoule/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/rejuran/healer-turnover-ampoule/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/rejuran/healer-turnover-ampoule/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/rejuran/healer-turnover-ampoule/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/rejuran/healer-turnover-ampoule/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/rejuran/healer-turnover-ampoule/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/rejuran/healer-turnover-ampoule/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/rejuran/healer-turnover-ampoule/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/rejuran/healer-turnover-ampoule/for/combination-skin