# REJURAN DUAL EFFECT AMPOULE for dry sensitive skin

**Lovi Fit: Average fit for dry sensitive skin.**
Dry Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/uk/p/rejuran/dual-effect-ampoule/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [REJURAN](https://lovi.care/skincare/uk/brands/rejuran)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/uk/best/moisturizers)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry sensitive skin; other moisturizers fit it better.

## Why this fit

- Offers moderate hydration and barrier support for your dry and sensitive skin, with hyaluronic acid and niacinamide providing essential moisture and smoothing texture. Squalane, ceramide NP, and oleic acid further enhance emollient action and barrier repair, which is beneficial for dry skin.
- The inclusion of ingredients like aloe barbadensis leaf juice and bisabolol offers soothing benefits that complement the hydration, making it generally comfortable for sensitive skin.
- The product is safe for your skin, as it contains no harsh or irritating ingredients and is well-suited for sensitive and dry skin types.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/rejuran/dual-effect-ampoule/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/uk/p/rejuran/dual-effect-ampoule/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/uk/p/rejuran/dual-effect-ampoule/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/uk/p/rejuran/dual-effect-ampoule/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/uk/p/rejuran/dual-effect-ampoule/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/uk/p/rejuran/dual-effect-ampoule/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/uk/p/rejuran/dual-effect-ampoule/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/rejuran/dual-effect-ampoule/for/dry-sensitive-skin): Average (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/rejuran/dual-effect-ampoule/for/oily-acne-prone-skin): Average

## Key ingredients

Blackberry Leaf Extract, Glycyrrhiza Glabra Extract Licorice Extract, Calendula Officinalis Flower Extract

## What the research says

- A lipid mixture enriched by ceramide NP with fatty acids of diverse chain lengths significantly improved skin barrier recovery rate, stratum corneum integrity, and hydration compared to a vehicle cream in healthy adult male volunteers with corticosteroid-impaired skin. ([Skin Pharmacology and Physiology, 2022](https://pubmed.ncbi.nlm.nih.gov/34348350/))
- Emulsions containing ceramides 1 and 3 improved skin hydration and reduced transepidermal water loss in sodium lauryl sulfate-irritated skin of fifteen healthy Asian women compared to a control emulsion. ([International Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18717861/))
- A blackberry and dill extract combination synergistically increased skin elasticity and induced elastogenesis compared to each ingredient alone and placebo. ([International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/32583541/))
- Tropical highland blackberry juice reduced UVB-mediated DNA damage and increased apoptosis in human epidermal keratinocytes and a reconstituted skin equivalent model. ([Photochemistry and Photobiology, 2013](https://pubmed.ncbi.nlm.nih.gov/23711186/))
- Strawberry and blackberry crude extracts, anthocyanin-enriched fractions, and proanthocyanidin-enriched fractions demonstrated anti-inflammatory effects through ROS reduction, gene expression inhibition, and NO suppression, while anthocyanin fractions promoted fibroblast migration in vitro. ([Food Research International, 2019](https://pubmed.ncbi.nlm.nih.gov/31108769/))
- Combining 755 nm alexandrite laser with topical licorice gel significantly reduces terminal hair counts compared to alexandrite laser with placebo in women with idiopathic hirsutism. ([Evidence-based Complementary and Alternative Medicine, 2015](https://pubmed.ncbi.nlm.nih.gov/26273313/))
- Licochalcone A activated Nrf2 signaling, elevated cytoprotective enzymes, increased the reduced-to-oxidized glutathione ratio, and decreased reactive oxygen species in human fibroblasts and neutrophils, while a LicA-rich licorice extract lowered UVA-induced oxidative processes in vivo. ([Experimental Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25381913/))
- Bioactive glycyrrhizic acid and oxymatrine ionic liquid self-assembled nanomicelles significantly promoted the transdermal permeation, subcutaneous retention, and anti-photoaging efficacy of palmitoyl pentapeptide-4 in cellular and animal models compared to unformulated peptide. ([Advanced Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39783908/))
- Topical application of Calendula officinalis extract cream significantly improved skin hydration and firmness (reflected in significant changes in R0 and R6 parameters) in 21 healthy human volunteers compared to a base cream. ([Acta Poloniae Pharmaceutica, 2011](https://pubmed.ncbi.nlm.nih.gov/21928714/))
- Treatment with standardized extract of Calendula officinalis L. led to a shorter epithelization time and faster healing speed compared to mineral oil in patients with acute skin loss wounds of the hand and fingers healing by secondary intention. ([Tissue Barriers, 2022](https://pubmed.ncbi.nlm.nih.gov/34674610/))
- Topical administration of Calendula provides weak evidence of effectiveness in acute and chronic wounds compared to standard treatments based on a narrative review of available trials. ([Wounds, 2008](https://pubmed.ncbi.nlm.nih.gov/25941793/))

## What reviewers say

This ampoule is widely praised for delivering the "glass skin" look, with users reporting immediate improvements in hydration, radiance, and skin texture. It is particularly favored by those with aging or damaged skin for its ability to smooth fine lines and repair the skin barrier using its signature salmon DNA (PDRN) formula, though its high price point is a common contention.

- Liked: Instant Glow (mostly mentioned)
- Disliked: High price point (mostly mentioned)
- Liked: Deep Hydration (often mentioned)
- Liked: Texture Smoothing (often mentioned)
- Disliked: Packaging issues (often mentioned)
- Liked: Fast Absorption (sometimes noted)
- Liked: Soothing & Repair (sometimes noted)
- Disliked: Breakouts/Irritation (rarely noted)
- Disliked: Heavy/Sticky finish (rarely noted)
- Disliked: Not hydrating enough (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using this moisturizer 3 times a week and move to daily use if your dry skin tolerates it well.
- Apply this moisturizer after cleansing and toner in the morning, or after your serum in the evening. Always pair it with SPF in the morning.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing it harshly to protect your sensitive skin.
- Apply the moisturizer on slightly damp skin to help with hydration absorption. This also works well for dry and flaky skin types.
- Do a patch test before your first use. Avoid the eye area to prevent any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does REJURAN Dual Effect Ampoule work for dry sensitive skin?

This moisturizing treatment works moderately well for dry and sensitive skin, providing basic hydration and soothing care through ingredients like hyaluronic acid, niacinamide, and bisabolol. It helps maintain comfort, but a product of this type needs multiple forms of hyaluronic acid, pro vitamin B5, and ceramides to give dry and sensitive skin the intense hydration and strong barrier support it needs.
Sources: [Skin Pharmacology and Physiology, 2022](https://pubmed.ncbi.nlm.nih.gov/34348350/)

### Which ingredients make this ampoule a good fit for dry sensitive skin?

This ampoule fits dry sensitive skin well thanks to hyaluronic acid and niacinamide for moisture, alongside squalane, ceramide NP, and oleic acid to repair the skin barrier. Aloe juice and bisabolol help calm the skin, while a moisturizing treatment for this skin type needs multiple forms of hyaluronic acid, pro vitamin B5, and ceramides for deep hydration and strong moisture retention.

### What does Blackberry Leaf Extract do for dry sensitive skin?

Blackberry leaf extract helps calm dry sensitive skin while making it feel soft and smooth. It is unlikely to cause irritation and may help protect the skin barrier against daily dryness.

### What does Licorice Extract do for dry sensitive skin?

Licorice extract helps calm dry sensitive skin by reducing redness and irritation while protecting against daily stress. It supports skin comfort and helps keep the skin barrier feeling smooth and balanced.
Sources: [Scientific Reports, 2020](https://pubmed.ncbi.nlm.nih.gov/33335246/), [Clinics in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22507050/)

### Where does this ampoule go in a skincare routine for dry sensitive skin?

This ampoule goes in your evening routine, applied after your toner and before your moisturizer. Using it at night keeps things simple and gives your skin extra safety around sun exposure.

### Can I use this ampoule with retinol, and in what order?

You can use this ampoule with retinol by applying the ampoule first to help calm and hydrate your skin before using retinol. Using a barrier-supporting product like this helps keep dry, sensitive skin comfortable and reduces the irritation often caused by retinol.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this ampoule?

You can use this moisturizing treatment in the evening as part of your routine, and some treatments like this can also be used in the morning or twice a day. Daily application helps improve skin moisture and keeps dry skin feeling soft and comfortable.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this ampoule clog pores, cause breakouts or purging for dry sensitive skin?

This ampoule is unlikely to cause breakouts or clogged pores on your dry sensitive skin. Reviewers rarely mention breakouts or irritation, and the formula is safe without harsh ingredients.

### Can I use this ampoule around the eyes or on my body?

You can use this moisturizing treatment around your eyes and on your body, though the skin around the eyes is much thinner and more delicate than body skin. Hyaluronic acid and botanical extracts help hydrate and smooth these areas safely, but dry skin often needs richer barrier-repair creams with heavier oils and ceramides to stay fully comfortable.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37896378/)

### Is this ampoule fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry sensitive skin

- [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/uk/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/dry-sensitive-skin) — Superior fit — £34.00 at Amazon
- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/uk/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/dry-sensitive-skin) — High fit — £18.40 at Amazon
- [Kiehl's Midnight Recovery Concentrate](https://lovi.care/skincare/uk/p/kiehl-s/midnight-recovery-concentrate/for/dry-sensitive-skin) — High fit — £52.50 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/uk/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — £8.29 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/uk/p/clarins/soothing-toning-lotion/for/dry-sensitive-skin) — Superior fit — £17.91 at Amazon
- Moisturizer with Sun Protection: [Real Barrier Mild Sun Cream](https://lovi.care/skincare/uk/p/real-barrier/mild-sun-cream/for/dry-sensitive-skin) — Superior fit — £19.01 at Amazon

## Where to buy

- Amazon.co.uk: £41.00 (https://www.amazon.co.uk/dp/B09Z5N7KYD?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Blackberry Leaf Extract, Glycyrrhiza Glabra Extract Licorice Extract, Calendula Officinalis Flower Extract, Aloe Barbadensis Leaf Juice, Blueberry Fruit Extract, Morus Nigra Fruit Extract, Peg-6, Glycerin, Water, Hyaluronic Acid, Niacinamide, Dipropylene Glycol, Butylene Glycol, 1,2-Hexanediol, Carbomer, Gerotine Hydrolyzed Dna, Hydrolyzed Dna, Xanthan Gum, Polysorbate 20, Adenosine, Tocopheryl Acetate, Bisabolol, Arbutin, Ethylhexylglycerin, Caprylyl Glycol, Hexylene Glycol, Trehalose, Urea, Serine, Pentylene Glycol, Glyceryl Polyacrylate, Algin, Pullulan, Disodium Phosphate, Potassium Phosphate, Squalane, Hydrogenated Lecithin, Ceramide Np, Oleic Acid, Inulin Lauryl Carbamate, Cholesterol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/rejuran/dual-effect-ampoule/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/rejuran/dual-effect-ampoule/for/dry-sensitive-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/rejuran/dual-effect-ampoule/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/rejuran/dual-effect-ampoule/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/rejuran/dual-effect-ampoule/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/rejuran/dual-effect-ampoule/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/rejuran/dual-effect-ampoule/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/rejuran/dual-effect-ampoule/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/rejuran/dual-effect-ampoule/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/rejuran/dual-effect-ampoule/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/rejuran/dual-effect-ampoule/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/rejuran/dual-effect-ampoule/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/rejuran/dual-effect-ampoule/for/dry-sensitive-skin