# Prequel Barrier Therapy Skin Protectant Cream for dry sensitive skin

**Lovi Fit: Superior fit for dry sensitive skin.**
Dry Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/uk/p/prequel/barrier-therapy-skin-protectant-cream/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [Prequel](https://lovi.care/skincare/uk/brands/prequel)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best products for dry sensitive skin.

## Why this fit

- Excellent suitability for your dry and sensitive skin as oat and ceramides provide soothing and barrier-repairing functions, while shea butter and glycerin offer emollient and humectant actions to support your skin barrier.
- The formulation excels in barrier repair with ceramides, cholesterol, and oat, enhancing resilience and addressing dryness or flakiness effectively.
- The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/prequel/barrier-therapy-skin-protectant-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/uk/p/prequel/barrier-therapy-skin-protectant-cream/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/uk/p/prequel/barrier-therapy-skin-protectant-cream/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/uk/p/prequel/barrier-therapy-skin-protectant-cream/for/sensitive-skin): Superior
- [Acne-prone skin](https://lovi.care/skincare/uk/p/prequel/barrier-therapy-skin-protectant-cream/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/uk/p/prequel/barrier-therapy-skin-protectant-cream/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/uk/p/prequel/barrier-therapy-skin-protectant-cream/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/prequel/barrier-therapy-skin-protectant-cream/for/dry-sensitive-skin): Superior (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/prequel/barrier-therapy-skin-protectant-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Oat, Multi-Ceramides, Allantoin, Adenosine

## What the research says

- Application of Body Lotion for 5 weeks on cosmetic dry skin improved barrier properties, increased levels of cholesterol, ceramides, and long-chain fatty acids, increased beneficial skin bacteria, and enhanced microbiome functional potential compared to baseline. ([Scientific Reports, 2022](https://pubmed.ncbi.nlm.nih.gov/35340018/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A repair cream containing Rhealba oat plantlets extract, l-ALA-l-GLU dipeptide, and hyaluronic acid provided immediate relief and was judged by doctors as good or very good in 96.8% of cases for wound healing in 2,363 patients following dermatological acts. ([Clinical, Cosmetic and Investigational Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/30519069/))
- Topically applied Avena sativa and Avena Rhealba oatmeal extracts significantly reduced skin irritation parameters including a* parameter increase and blood flow increase compared to vehicle in 12 healthy individuals subjected to the sodium lauryl sulfate irritation model. ([Skin Pharmacology and Applied Skin Physiology, 2002](https://pubmed.ncbi.nlm.nih.gov/11867969/))
- Colloidal oat extracts diminished pro-inflammatory cytokines in vitro and colloidal oat lotion improved skin dryness, scaling, roughness, and itch intensity in healthy female subjects compared to baseline. ([Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25607907/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))
- Topical adenosine treatment significantly increased the anagen hair growth rate and thick hair rate compared to placebo in Japanese women with female pattern hair loss over 12 months. ([The Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19239555/))
- Topical application of a disodium adenosine monophosphate-based formulation reduced wrinkles and hyperpigmentation while improving hydration, barrier function, skin lifting, and epidermal turnover in female participants. ([International Journal of Molecular Sciences, 2026](https://pubmed.ncbi.nlm.nih.gov/42278371/))
- Adenosine and cordycepin stimulate the Wnt/beta-catenin signaling pathway through adenosine receptor and PKA activation, promoting cell proliferation, migration, and growth factor secretion in cultured dermal fibroblasts. ([International Journal of Molecular Sciences, 2021](https://pubmed.ncbi.nlm.nih.gov/34070360/))

## What reviewers say

While the vast majority find it deeply hydrating and an excellent value for the size, a subset of users reported burning sensations or breakouts, and the product faced a significant recall in 2024 due to contamination concerns.

- Liked: Great value (often mentioned)
- Liked: Non-greasy texture (often mentioned)
- Liked: Versatile use (sometimes noted)
- Disliked: Availability issues (sometimes noted)
- Disliked: Burning sensation (sometimes noted)
- Disliked: Recall history (sometimes noted)
- Disliked: Caused breakouts (rarely noted)

## Questions and answers

### What makes Prequel Barrier Therapy Skin Protectant Cream one of the best fits for dry sensitive skin?

This cream is an exceptional fit because oat and multi-ceramides soothe and repair your skin barrier, while shea butter and glycerin soften dry areas and hold in moisture. The formula enhances resilience and addresses flakiness effectively without any harsh ingredients that might cause irritation.
Sources: [Scientific Reports, 2022](https://pubmed.ncbi.nlm.nih.gov/35340018/)

### Which ingredients make this cream a good fit for dry sensitive skin?

Oat, multi-ceramides, shea butter, and glycerin make this cream a great fit because they soothe, repair the skin barrier, and keep dry skin soft and hydrated. These ingredients enhance skin resilience and address flakiness while maintaining an excellent safety profile without harsh irritants.
Sources: [Scientific Reports, 2022](https://pubmed.ncbi.nlm.nih.gov/35340018/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Oat do for dry sensitive skin?

Oat helps soothe dry sensitive skin by calming irritation, reducing redness, and easing itchiness. It also supports the skin barrier to keep moisture locked in, which makes dry skin feel softer and smoother.
Sources: [Journal of Drugs in Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/27272074/)

### What do Ceramides do for dry sensitive skin?

Ceramides help strengthen dry, sensitive skin by locking in moisture and repairing the outer barrier, which makes skin feel softer and less irritated. This type of care helps prevent dryness and keeps skin calm and comfortable.
Sources: [The British Journal of Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34921679/), [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/39492723/)

### Where does this cream go in a skincare routine for dry sensitive skin?

This cream goes at the end of your evening routine to lock in moisture and soothe your skin, and it is also gentle enough for everyday use. Using a moisturizer helps improve skin hydration and repairs the skin barrier, keeping dry and sensitive skin soft and smooth.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [Scientific Reports, 2022](https://pubmed.ncbi.nlm.nih.gov/35340018/)

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol by applying the cream after your retinol treatment to help calm the skin and reduce dryness. This product is very safe for dry and sensitive skin, and barrier-repairing moisturizers are known to improve skin tolerability when using strong treatments like retinol.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this cream?

You can use this cream daily as part of your regular routine to help keep your skin feeling soft and comfortable. Consistent daily moisturizing significantly improves dryness and supports skin barrier function.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [Scientific Reports, 2022](https://pubmed.ncbi.nlm.nih.gov/35340018/)

### Can this cream clog pores, cause breakouts or purging for dry sensitive skin?

This cream is unlikely to clog pores or cause breakouts for dry sensitive skin, as its formula features soothing and barrier-repairing ingredients without harsh additives. Reviewers do report a low chance of breakouts, but the product's safety profile is excellent.
Sources: [Scientific Reports, 2022](https://pubmed.ncbi.nlm.nih.gov/35340018/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for dry sensitive skin

- [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/uk/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/dry-sensitive-skin) — Superior fit — £14.74 at Amazon
- [The Ordinary Natural Moisturizing Factors + HA](https://lovi.care/skincare/uk/p/the-ordinary/natural-moisturizing-factors-ha/for/dry-sensitive-skin) — Superior fit — £11.40 at Amazon
- [L'Occitane Immortelle Divine Cream](https://lovi.care/skincare/uk/p/l-occitane/immortelle-divine-cream/for/dry-sensitive-skin) — Superior fit — £61.50 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/uk/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — £8.29 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/uk/p/clarins/soothing-toning-lotion/for/dry-sensitive-skin) — Superior fit — £17.91 at Amazon
- Moisturizer with Sun Protection: [Real Barrier Mild Sun Cream](https://lovi.care/skincare/uk/p/real-barrier/mild-sun-cream/for/dry-sensitive-skin) — Superior fit — £19.01 at Amazon

## Where to buy

No store in United Kingdom has a checked price for this product, so the page shows none.

## Ingredients

Oat, Water, Carthamus Tinctorius Seed Oil, Cetyl Alcohol, Glycerin, Butyrospermum Parkii Butter, Caprylic Capric Triglyceride, Dimethicone, C10-18 Triglycerides, Allantoin, Adenosine, Cetearyl Olivate, Sorbitan Olivate, Ceramide Ap, Ceramide Eos, Ceramide Eop, Ceramide Np, Ceramide Ns, Cholesterol, Caprooyl Phytosphingosine, Caprooyl Sphingosine, Glycolipids, Sodium Stearoyl Glutamate, Behenic Acid, Ceteareth-25, Glycine Soja Sterols, Hydrogenated Palm Glycerides, Hydrogenated Palm Glycerides Kernel, Carbomer, Phenoxyethanol, Ethylhexylglycerin, Tocopheryl Acetate, Tetrasodium Glutamate Diacetate, Sodium Hydroxide
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/prequel/barrier-therapy-skin-protectant-cream/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/prequel/barrier-therapy-skin-protectant-cream/for/dry-sensitive-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/prequel/barrier-therapy-skin-protectant-cream/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/prequel/barrier-therapy-skin-protectant-cream/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/prequel/barrier-therapy-skin-protectant-cream/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/prequel/barrier-therapy-skin-protectant-cream/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/prequel/barrier-therapy-skin-protectant-cream/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/prequel/barrier-therapy-skin-protectant-cream/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/prequel/barrier-therapy-skin-protectant-cream/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/prequel/barrier-therapy-skin-protectant-cream/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/prequel/barrier-therapy-skin-protectant-cream/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/prequel/barrier-therapy-skin-protectant-cream/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/prequel/barrier-therapy-skin-protectant-cream/for/dry-sensitive-skin