# Perricone MD Rebalancing Elixir for combination skin

**Lovi Fit: High fit for combination skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/uk/p/perricone-md/rebalancing-elixir/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [Perricone MD](https://lovi.care/skincare/uk/brands/perricone-md)
Category: [Serums and treatments](https://lovi.care/skincare/uk/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for combination skin.

## Why this fit

- Highly suitable for combination skin, this formula utilizes ingredients like Sodium PCA and Glycerin for humectant action, alongside Annona Cherimola Fruit Extract to help regulate sebum, though more potent agents could further optimize oil control for your oily shine.
- Capryloyl glycine and sodium bicarbonate are included to mattify and control oil production, offering excellent treatment for oily skin.
- The product is safe for your combination skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/perricone-md/rebalancing-elixir/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/uk/p/perricone-md/rebalancing-elixir/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/uk/p/perricone-md/rebalancing-elixir/for/combination-skin): High (this page)
- [Sensitive skin](https://lovi.care/skincare/uk/p/perricone-md/rebalancing-elixir/for/sensitive-skin): Superior
- [Acne-prone skin](https://lovi.care/skincare/uk/p/perricone-md/rebalancing-elixir/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/uk/p/perricone-md/rebalancing-elixir/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/uk/p/perricone-md/rebalancing-elixir/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/perricone-md/rebalancing-elixir/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/perricone-md/rebalancing-elixir/for/oily-acne-prone-skin): High

## Key ingredients

Cannabidiol, Mushroom Complex, Cherimoya Fruit Extract, Capryloyl Glycine, Sodium Pca

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Menstrual pads containing sodium bicarbonate caused no clinical signs or subclinical vulvar skin irritant reactions in 50 healthy women after 24 hours of patch testing. ([The Journal of Reproductive Medicine, 1991](https://pubmed.ncbi.nlm.nih.gov/1658321/))
- Topical nano-cannabidiol cream reduced UV-A-induced epidermal hyperplasia, nuclear DNA base lesions, and mitochondrial DNA deletions compared with vehicle in nineteen participants. ([Journal of the American Academy of Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/39025264/))
- Topical application of an anti-aging gel containing EPA and CBD reduced inflammatory agents, decreased crow's feet and fine line wrinkle volume, reduced the subepidermal low-echogenic band by 8.8%, and increased skin hydration by 31.2% and elasticity by 25.6% in 33 participants over 56 days compared to baseline. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37264742/))
- Daily application of a novel retinol and cannabidiol combination topical improved global skin quality across 13 domains, including visible pores, dehydration, surface roughness, and static and dynamic wrinkles, in 10 patients with facial skin imperfections. ([Aesthetic Surgery Journal. Open Forum, 2022](https://pubmed.ncbi.nlm.nih.gov/35274096/))
- Skin care regimens containing beta-glucan improved hemoglobin index, skin hydration, and transepidermal water loss compared to vehicle control in 20 patients undergoing fractional laser therapy. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/))
- Treatment with topical formulations containing beta-glucan combined with nanofractional radiofrequency plus magnetic nanofractional radiofrequency showed the best efficacy and was tolerable and effective in Chinese women with abdominal stretch marks compared to control groups. ([Dermatology and Therapy, 2023](https://pubmed.ncbi.nlm.nih.gov/37171578/))
- Topical beta-glucan mildly improved striae gravidarum, 1565-nm non-ablative fractional laser showed better results than topical beta-glucan, and the combined strategy further improved striae gravidarum atrophy compared to single treatment. ([The Journal of Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35570397/))
- Topical application of a formulation containing capryloyl glycine 4% significantly decreased hair density, median hair length, and terminal hair density on the forearms compared to placebo in female patients with hypertrichosis after 120 days. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33347705/))
- A novel natural carrier-free assembled gel composed of sodium pyrrolidone carboxylate and baicalin alleviates UVB-induced skin photodamage by scavenging reactive oxygen species, protecting mitochondria, restoring oxidative homeostasis, inhibiting inflammatory responses, and regulating collagen-related proteins. ([Biomaterials Advances, 2026](https://pubmed.ncbi.nlm.nih.gov/41129958/))

## What reviewers say

Most users find it provides lightweight hydration that absorbs quickly without feeling heavy, leading to improved skin balance and texture. A moderate number of users feel the product is too expensive for the results, and a low number dislike the natural scent or do not see dramatic anti-aging effects.

- Liked: Soothes sensitive skin (mostly mentioned)
- Liked: Lightweight hydration (often mentioned)
- Liked: Good for layering (sometimes noted)
- Liked: Improves skin texture (sometimes noted)
- Disliked: Expensive for results (sometimes noted)
- Disliked: Not a miracle worker (rarely noted)
- Disliked: Product availability issues (rarely noted)
- Disliked: Unpleasant natural scent (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Perricone MD Rebalancing Elixir a great fit for combination skin?

Perricone MD Rebalancing Elixir is a great fit for combination skin because it uses sodium PCA and glycerin to keep dry areas soft and hydrated while incorporating capryloyl glycine and fruit extract to help control oil. It is very safe for your skin, with no risk of irritation since it leaves out harsh ingredients.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this elixir a good fit for combination skin?

Sodium PCA and glycerin help keep your dry areas soft and hydrated, while cherimoya fruit extract, capryloyl glycine, and sodium bicarbonate work to calm and control oil on your shiny zones. This blend is unlikely to cause irritation and is a great match for balancing combination skin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Cannabidiol do for combination skin?

Cannabidiol helps calm combination skin by reducing redness and balancing oil production in areas that need it. It is unlikely to cause irritation and may protect the skin barrier while keeping oily and dry spots comfortable.
Sources: [The Journal of Clinical Investigation, 2014](https://pubmed.ncbi.nlm.nih.gov/25061872/), [Archives of Dermatological Research, 2024](https://pubmed.ncbi.nlm.nih.gov/38904694/)

### What does Mushroom Complex do for combination skin?

Mushroom Complex helps hydrate and calm combination skin while providing antioxidant protection to keep the face smooth and balanced. These mushroom extracts support overall skin health and help maintain a clear, even complexion.
Sources: [Gels, 2025](https://pubmed.ncbi.nlm.nih.gov/39852004/), [Archives of Dermatological Research, 2025](https://pubmed.ncbi.nlm.nih.gov/40057933/)

### Where does this elixir go in a skincare routine for combination skin?

This elixir goes in the evening routine after cleansing and toning, as treatments are placed in the evening for simplicity and extra safety around sun exposure. It is safe for your combination skin, with no risks of irritation due to the absence of harsh ingredients.

### Can I use this elixir with retinol, and in what order?

You can use this treatment alongside retinol by applying the elixir before your moisturizer in your evening routine, while keeping retinol for a separate night or step to avoid irritation. This product is unlikely to cause irritation on combination skin because it lacks harsh ingredients, helping to keep your skin calm and balanced.

### How often should I use this elixir?

Apply this treatment in your evening routine, using it once daily for best results. It is safe for your combination skin and is unlikely to cause irritation.

### Can this elixir clog pores, cause breakouts or purging for combination skin?

This elixir is unlikely to clog pores, cause breakouts, or lead to purging on combination skin. It has a high safety profile with no harsh ingredients, meaning it is very unlikely to cause irritation.
Sources: [The Journal of Reproductive Medicine, 1991](https://pubmed.ncbi.nlm.nih.gov/1658321/)

### Is this elixir fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [Dr. Ceuracle Tea Tree Purifine 95 Essence](https://lovi.care/skincare/uk/p/dr-ceuracle/tea-tree-purifine-95-essence/for/combination-skin) — High fit — £21.11 at Amazon
- [SKIN1004 Madagascar Centella Probio-cica Intensive Ampoule](https://lovi.care/skincare/uk/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/combination-skin) — High fit — £12.79 at Amazon
- [Purito Galacto Niacin 97 Power Essence](https://lovi.care/skincare/uk/p/purito/galacto-niacin-97-power-essence/for/combination-skin) — Average fit — £16.80 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/uk/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — £14.99 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/uk/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — £30.37 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/uk/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — £14.80 at Amazon

## Where to buy

No store in United Kingdom has a checked price for this product, so the page shows none.

## Ingredients

Water, 1,2-Hexanediol, Sodium Pca, Triethyl Citrate, Propanediol, Capryloyl Glycine, Glycerin, Annona Cherimola Fruit Extract, Cannabidiol, Ganoderma Lucidum Stem Extract Mushroom Stem Extract, Grifola Frondosa Fruiting Body Extract, Sodium Bicarbonate, Caprylhydroxamic Acid, Sodium Hydroxide, Citric Acid, Cannabis Sativa Glycereth-8 Esters Seed Oil, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Sodium Citrate, Lentinus Edodes Mycelium Extract, Sodium Dehydroacetate, Phenylpropanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/perricone-md/rebalancing-elixir/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/perricone-md/rebalancing-elixir/for/combination-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/perricone-md/rebalancing-elixir/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/perricone-md/rebalancing-elixir/for/combination-skin
- France: https://lovi.care/skincare/fr/p/perricone-md/rebalancing-elixir/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/perricone-md/rebalancing-elixir/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/perricone-md/rebalancing-elixir/for/combination-skin
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- Canada: https://lovi.care/skincare/ca/p/perricone-md/rebalancing-elixir/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/perricone-md/rebalancing-elixir/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/perricone-md/rebalancing-elixir/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/perricone-md/rebalancing-elixir/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/perricone-md/rebalancing-elixir/for/combination-skin