# PanOxyl PM Overnight Spot Patches for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/uk/p/panoxyl/pm-overnight-spot-patches/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [PanOxyl](https://lovi.care/skincare/uk/brands/panoxyl)
Category: [Serums and treatments](https://lovi.care/skincare/uk/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other serums fit it better.

## Why this fit

- This product offers excellent spot treatment for blemishes due to the hydrocolloid dressing's ability to absorb exudate and protect the affected area, while glycerin and dimethicone help balance hydration and skin texture for your combination skin.
- While it provides general skincare benefits like hydration and cleansing, it lacks specialized ingredients to target oily shine, which is your main concern.
- The safety profile is excellent, with no risks of irritation for your combination skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/panoxyl/pm-overnight-spot-patches/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/uk/p/panoxyl/pm-overnight-spot-patches/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/uk/p/panoxyl/pm-overnight-spot-patches/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/uk/p/panoxyl/pm-overnight-spot-patches/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/uk/p/panoxyl/pm-overnight-spot-patches/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/uk/p/panoxyl/pm-overnight-spot-patches/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/uk/p/panoxyl/pm-overnight-spot-patches/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/panoxyl/pm-overnight-spot-patches/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/panoxyl/pm-overnight-spot-patches/for/oily-acne-prone-skin): Average

## Key ingredients

Hydrocolloid Dressing, Glycerin, Dimethicone, Sodium Chloride, Xanthan Gum

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Daily application of hydrocolloid dressing completely prevented nasogastric tube-related pressure injuries, whereas skin care interventions showed no significant preventive effect compared to the control group in intensive care unit patients. ([Journal of Tissue Viability, 2024](https://pubmed.ncbi.nlm.nih.gov/39289093/))
- Hydration of scars for 2 months resulted in significantly reduced itching, somewhat reduced pain, and increased pliability by 10% for both hydrocolloid dressing and moisturizer treatments in patients with keloids or hypertrophic scars, with no change in physical parameters. ([Dermatologic Surgery, 1996](https://pubmed.ncbi.nlm.nih.gov/8874525/))
- Adjunctive hydrocolloid dressing with 0.1% mometasone furoate cream significantly increased treatment efficacy and cost-effectiveness compared to topical steroid alone in patients with moderate to severe lichen simplex chronicus. ([Skin Health and Disease, 2023](https://pubmed.ncbi.nlm.nih.gov/37538322/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups. ([Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/))
- A dimethicone skin protectant lotion significantly decreased visual scoring and transepidermal water loss compared to vehicle control and SLS-only treated sites in 12 healthy humans exposed to sodium lauryl sulfate. ([Skin Research and Technology, 2000](https://pubmed.ncbi.nlm.nih.gov/11428946/))
- Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms. ([Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/))
- Calcium hydroxylapatite diluted with normal saline combined with microfocused ultrasound with visualization improved age-related changes in the lower face, neck, and décolleté and stimulated collagen and elastin fibers in 20 subjects. ([Journal of Drugs in Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32272518/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))
- Topical application of magnetized saline water serum improved skin hydration, reduced transepidermal water loss, sebum content, melanin index, and erythema index, and activated autophagy by increasing Beclin-1 and decreasing mTOR in females wanting to enhance facial and neck skin appearance. ([Cureus, 2023](https://pubmed.ncbi.nlm.nih.gov/38130575/))
- Biodegradable wound dressings functionalized with silver nanoparticles showed >99% pathogen growth inhibition, bactericidal effects, free radical scavenging, reduced inflammatory response in macrophages, and accelerated wound healing in animals. ([International Journal of Biological Macromolecules, 2022](https://pubmed.ncbi.nlm.nih.gov/35780920/))
- A topical xanthan gum nanogel containing gamma-oryzanol-loaded nanostructured lipid carriers and nanosized TiO2 and MBBT filters demonstrated high photoprotection with an SPF of 34 and no skin irritation or sensitization in a rat model. ([Pharmaceuticals, 2023](https://pubmed.ncbi.nlm.nih.gov/37242453/))
- Dense chitosan-xanthan membranes associated with multipotent mesenchymal stromal cells accelerated wound healing in Wistar rats compared to untreated conditions, demonstrating safety and feasibility for dermo-epidermal wound treatment. ([Journal of Biomaterials Applications, 2015](https://pubmed.ncbi.nlm.nih.gov/25281644/))

## Why other serums fit combination skin better

- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))
- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))

## What reviewers say

Based on a very large amount of data, users with acne-prone and sensitive skin widely praise these hydrocolloid patches for effectively flattening whiteheads and absorbing fluids overnight while preventing skin picking. Results are mixed for deep cystic acne, and some users find the patches slightly thicker than competitors, making them better suited for nighttime use.

- Liked: Absorbs fluid effectively (mostly mentioned)
- Liked: Prevents skin picking (often mentioned)
- Liked: Good value for money (sometimes noted)
- Liked: Strong overnight adhesion (sometimes noted)
- Disliked: Ineffective on cystic acne (sometimes noted)
- Disliked: Adhesion residue (rarely noted)
- Disliked: Difficult packaging (rarely noted)
- Disliked: Too thick/visible (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does PanOxyl PM Overnight Spot Patches work for combination skin?

PanOxyl PM Overnight Spot Patches works well for occasional blemishes on combination skin, but it lacks ingredients to target oily shine. Combination skin needs products with niacinamide, propolis, or zinc PCA to regulate oiliness and balance hydration without causing excess oil or dryness.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this treatment a good fit for combination skin?

Hydrocolloid dressing, glycerin, and dimethicone make this treatment a good fit by absorbing spot fluid while keeping skin hydrated and smooth. Because it lacks ingredients to manage oily shine, a product of this type needs niacinamide, propolis, or zinc PCA to regulate oiliness and balance combination skin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Hydrocolloid Dressing do for combination skin?

Hydrocolloid dressings are unlikely to suit combination skin well, as they are designed to manage moisture in specific wound care rather than everyday facial needs. A product for combination skin typically needs balancing ingredients that hydrate dry areas while keeping oily zones clear.
Sources: [Journal of Gerontological Nursing, 1993](https://pubmed.ncbi.nlm.nih.gov/8509607/)

### What does Glycerin do for combination skin?

Glycerin helps keep combination skin soft and smooth by pulling moisture in and keeping it there. It improves hydration and supports your skin barrier, which is unlikely to cause irritation.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Where does this treatment go in a skincare routine for combination skin?

This treatment goes in the evening routine after cleansing and before moisturizing. Combination skin needing a spot treatment like this also benefits from specialized ingredients that target oily shine.

### Can I use this treatment with salicylic acid, and in what order?

You can use this treatment alongside salicylic acid by applying your salicylic acid product first, letting it dry, and then placing the patch over the blemish. This spot treatment is unlikely to cause irritation on your combination skin since it lacks harsh ingredients, and it works well to absorb fluid from spots while glycerin and dimethicone balance your skin texture. Because this product does not target oily shine, combination skin also needs ingredients that control oil and clear pores.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### How often should I use this treatment?

You can use this treatment overnight whenever you have a blemish to target. It is very gentle and unlikely to cause any irritation on your combination skin.

### Can this treatment clog pores, cause breakouts or purging for combination skin?

This treatment is unlikely to cause breakouts or clog pores on combination skin, as it has a very safe formula with no harsh or irritating ingredients. However, it lacks specific ingredients to control oily shine, which combination skin often needs.

### Is this treatment fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/uk/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/combination-skin) — Superior fit — £36.96 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/uk/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin) — Superior fit — £24.20 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/uk/p/augustinus-bader/the-serum/for/combination-skin) — Superior fit — £248.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/uk/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — £14.99 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/uk/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — £30.37 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/uk/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — £14.80 at Amazon

## Where to buy

No store in United Kingdom has a checked price for this product, so the page shows none.

## Ingredients

Hydrocolloid Dressing, Carbomer Homopolymer Type C, Carbomer Interpolymer Type A, Decyl Glucoside, Dimethicone, Dioctyl Sodium Sulfosuccinate, Glycerin, Palmitic Acid, Polyacrylate Crosspolymer-6, Polyoxyl 40 Stearate, Propanediol, Water, Silica, Sodium Chloride, Sodium Citrate, Sodium Hydroxide, Sodium Laurylglucosides Hydroxypropylsulfonate, Sorbitan Stearate, Stearic Acid, T-Butyl Alcohol, Xanthan Gum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/panoxyl/pm-overnight-spot-patches/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/panoxyl/pm-overnight-spot-patches/for/combination-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/panoxyl/pm-overnight-spot-patches/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/panoxyl/pm-overnight-spot-patches/for/combination-skin
- France: https://lovi.care/skincare/fr/p/panoxyl/pm-overnight-spot-patches/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/panoxyl/pm-overnight-spot-patches/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/panoxyl/pm-overnight-spot-patches/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/panoxyl/pm-overnight-spot-patches/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/panoxyl/pm-overnight-spot-patches/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/panoxyl/pm-overnight-spot-patches/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/panoxyl/pm-overnight-spot-patches/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/panoxyl/pm-overnight-spot-patches/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/panoxyl/pm-overnight-spot-patches/for/combination-skin