# Olay Regenerist Retinol 24 Night Facial Serum for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/uk/p/olay-regenerist/retinol-24-night-facial-serum/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [Olay Regenerist](https://lovi.care/skincare/uk/brands/olay-regenerist)
Category: [Serums and treatments](https://lovi.care/skincare/uk/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other serums fit it better.

## Why this fit

- Offers moderate benefits for your combination skin, as niacinamide helps regulate oil production and retinol aids in desquamation, though it lacks specialized ingredients to directly target oily shine. Palmitoyl pentapeptide-4 and retinol work synergistically to improve skin texture and reduce the appearance of wrinkles.
- The serum provides general hydration and skin smoothing, which can indirectly help with oily shine by improving overall skin health.
- The formula is safe for your combination skin, with no harsh ingredients that would cause irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/olay-regenerist/retinol-24-night-facial-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/uk/p/olay-regenerist/retinol-24-night-facial-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/uk/p/olay-regenerist/retinol-24-night-facial-serum/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/uk/p/olay-regenerist/retinol-24-night-facial-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/uk/p/olay-regenerist/retinol-24-night-facial-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/uk/p/olay-regenerist/retinol-24-night-facial-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/uk/p/olay-regenerist/retinol-24-night-facial-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/olay-regenerist/retinol-24-night-facial-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/olay-regenerist/retinol-24-night-facial-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Retinol, Niacinamide, Palmitoyl Pentapeptide-4, Glycerin, Retinyl Propionate

## What the research says

- Topical palmitoyl pentapeptide (pal-KTTKS) provided significant improvement versus placebo control in the reduction of wrinkles and fine lines in Caucasian female subjects. ([International Journal of Cosmetic Science, 2005](https://pubmed.ncbi.nlm.nih.gov/18492182/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Over-the-counter retinol products provided only weak evidence for a mild ameliorating effect on fine facial skin wrinkle lines in randomized, double-blind, vehicle-controlled trials, and major methodological flaws call the validity of positive results into question. ([The Journal of Clinical and Aesthetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/34980969/))
- A cosmetic niacinamide/peptide/retinyl propionate regimen significantly improved periorbital wrinkle appearance relative to a 0.02% tretinoin regimen at 8 weeks with comparable benefits at 24 weeks, while demonstrating significantly better tolerability in 196 women. ([The British Journal of Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20374604/))
- A novel triple-active cosmetic formulation containing 4-hexylresorcinol, retinyl propionate, and niacinamide improved the visual appearance of photoageing similarly to 0.02% tretinoin and reversed a consensus gene signature associated with ageing in female adults while causing less skin irritation. ([International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/38685700/))

## Why other serums fit combination skin better

- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))
- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))

## What reviewers say

Based on a very large amount of data, this serum is highly praised for delivering significant anti-aging results like firmer skin and reduced fine lines, with a notable absence of typical retinol irritation. Its lightweight, hydrating, and fragrance-free formula is well-suited for sensitive skin, effectively improving texture and evening out skin tone over time.

- Liked: Smoother skin texture (mostly mentioned)
- Liked: Gentle and non-irritating (often mentioned)
- Liked: Lightweight and fast-absorbing (often mentioned)
- Liked: Brightens and evens tone (sometimes noted)
- Liked: Hydrating and plumping (sometimes noted)
- Disliked: Poor dropper design (sometimes noted)
- Disliked: Slow visible results (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Pilling or residue (rarely noted)
- Disliked: Texture preference (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Olay Retinol 24 work for combination skin?

This serum works moderately well for your combination skin, as it helps balance oil and smooth texture, though other products fit this skin type better. To work best for combination skin, a treatment of this type needs dedicated ingredients like zinc PCA or propolis to manage oily shine.
Sources: [International Journal of Cosmetic Science, 2005](https://pubmed.ncbi.nlm.nih.gov/18492182/)

### Which ingredients make this serum a good fit for combination skin?

Niacinamide helps regulate oil production while retinol and palmitoyl pentapeptide-4 improve skin texture and smooth fine lines. Glycerin provides general hydration to keep skin soft. Treatments that fit combination skin better need ingredients like zinc PCA or propolis to manage oily shine.
Sources: [International Journal of Cosmetic Science, 2005](https://pubmed.ncbi.nlm.nih.gov/18492182/)

### What does Retinol do for combination skin?

Retinol helps smooth fine lines, even out skin tone, and improve firmness in combination skin. It works by encouraging faster skin renewal and boosting collagen, though it may occasionally cause mild dryness or scaling while your skin adjusts.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/)

### What does Niacinamide do for combination skin?

Niacinamide helps balance oily areas by reducing excess shine and pore size while keeping dry patches hydrated and smooth. It also works to calm redness and even out skin tone, making it very suitable for combination skin.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Where does this serum go in a skincare routine for combination skin?

This serum goes in the evening routine after cleansing and toning, and before moisturizing. Combination skin works best with products that balance oil and shine while delivering lightweight hydration.

### Can I use it with vitamin C, and in what order?

You can use this serum with vitamin C by applying your vitamin C product in the morning and saving this treatment for your evening routine. Using them at separate times of day helps prevent potential irritation while letting your skin get the benefits of both ingredients.

### How often should I use this serum?

Apply this treatment in the evening as part of your routine. A product of this type needs specialized ingredients to directly target oily shine and balance combination skin.
Sources: [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/)

### Can it clog pores, cause breakouts or purging for combination skin?

This serum is unlikely to cause irritation for your combination skin, though reviewer complaints show that breakouts may occasionally happen. A product for this skin needs specialized ingredients to directly target oily shine alongside oil-regulating and smoothing ingredients.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/uk/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/combination-skin) — Superior fit — £36.96 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/uk/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin) — Superior fit — £24.20 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/uk/p/augustinus-bader/the-serum/for/combination-skin) — Superior fit — £248.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/uk/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — £14.99 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/uk/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — £30.37 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/uk/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — £14.80 at Amazon

## Where to buy

- Amazon.co.uk: £11.52 (https://www.amazon.co.uk/dp/B0852NGPQ5?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Dimethicone, Glycerin, Retinol, Retinyl Propionate, Niacinamide, Palmitoyl Pentapeptide-4, Dimethicone Crosspolymer, Polyacrylamide, Titanium Dioxide, C13-14 Isoparaffin, Dmdm Hydantoin, Mica, Polysorbate 20, Laureth-4, Laureth-7, Disodium Edta, Iodopropynyl Butylcarbamate, Caprylic Capric Triglyceride
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/olay-regenerist/retinol-24-night-facial-serum/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/olay-regenerist/retinol-24-night-facial-serum/for/combination-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/olay-regenerist/retinol-24-night-facial-serum/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/olay-regenerist/retinol-24-night-facial-serum/for/combination-skin
- France: https://lovi.care/skincare/fr/p/olay-regenerist/retinol-24-night-facial-serum/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/olay-regenerist/retinol-24-night-facial-serum/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/olay-regenerist/retinol-24-night-facial-serum/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/olay-regenerist/retinol-24-night-facial-serum/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/olay-regenerist/retinol-24-night-facial-serum/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/olay-regenerist/retinol-24-night-facial-serum/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/olay-regenerist/retinol-24-night-facial-serum/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/olay-regenerist/retinol-24-night-facial-serum/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/olay-regenerist/retinol-24-night-facial-serum/for/combination-skin