NUE Barrier Clear Treatment for combination skin
Live Probiotic
Dendriclear
Average
- HighCombination Skin Fit
- AverageEffectiveness
- HighSafety
Works for combination skin; other serums fit it better.
This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate treatment for your acne-prone combination skin as Live Probiotic and Dendriclear provide anti-inflammatory and antimicrobial actions to reduce acne lesions and blemishes.
- The formula also offers general skincare benefits like hydration and cleansing, which are supportive for your oily shine.
- The product is safe for your combination skin due to the absence of prohibited or harsh ingredients.
How to apply
- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
People Say
★4.5Overall rating based on 300+ reviewsIt is frequently highlighted as a gentle, effective solution for those with sensitive or breakout-prone skin who need barrier support alongside blemish control.
Highlights
Calms breakouts Often Mentioned
- “Cleared my acne right up”
- “calmed pustules”
- “reduced inflammatory spots”
Gentle on skin Often Mentioned
- “Lightweight serum”
- “no harsh ingredients”
- “great for sensitive skin”
Non-greasy formula Sometimes Noted
- “Sits under moisturizer”
- “leaves no trace”
- “lightweight liquid-suspension”
Strengthens barrier Sometimes Noted
- “Helps strengthen skin barrier”
- “skin was calmer”
- “promotes resilient skin”
Ineffective for some Rarely Noted
- “Didn't work for me”
- “no noticeable change”
- “results were minimal”
Price point Rarely Noted
- “Expensive for the size”
- “investment product”
- “costly for daily use”
Slow results Rarely Noted
- “Took time to see improvement”
- “not an overnight fix”
Sources: lovi.care, ipsy.com, thenueco.com, spacenk.com, cultbeauty.com, beautybay.com, and more
Questions and answers
How well does NUE Barrier Clear Treatment work for combination skin?
NUE Barrier Clear Treatment works moderately well for your combination skin by using Live Probiotic and Dendriclear to help calm acne and clear blemishes while keeping skin hydrated and clean. This type of treatment needs effective ingredients like niacinamide and zinc PCA to properly balance oiliness and give you the best results without causing irritation or dryness.
Which ingredients make this treatment a good fit for combination skin?
Live Probiotic and Dendriclear make this treatment a fit for your combination skin by providing anti-inflammatory and antimicrobial actions that help reduce acne lesions and blemishes. This treatment needs ingredients like niacinamide, propolis, and zinc PCA to regulate oiliness, enhance radiance, and provide optimal hydration without causing excess oiliness or dryness.
International Journal of Medical Sciences, 2021Experimental Dermatology, 2019
What does Live Probiotic do for combination skin?
Live Probiotic helps balance combination skin by supporting the skin microbiome, which calms irritation and maintains steady moisture levels across both dry and oily areas. It is unlikely to cause heavy buildup, though this product type needs lightweight, balancing ingredients to properly hydrate dry spots without making oily zones slick.
International Journal of Medical Sciences, 2021Nutrients, 2024
What does Dendriclear do for combination skin?
Dendriclear helps balance combination skin by targeting the causes of breakouts while keeping dry areas calm and comfortable. It is unlikely to cause irritation and works to keep your skin smooth and clear.
Where does this treatment go in a skincare routine for combination skin?
This treatment goes in the evening routine after cleansing and before moisturizing, as Lovi places active serums and treatments in the PM steps for simplicity and extra safety around sun exposure. A product of this type works best for combination skin when it includes soothing ingredients and gentle hydrators to calm blemishes while supporting oily areas.
Can I use this treatment with retinol, and in what order?
You can use this treatment with retinol by applying it at different times of day or on alternating days to help prevent irritation. For combination skin, a treatment of this type needs soothing ingredients and gentle hydration to keep the skin calm and balanced while using strong actives like retinol.
How often should I use this treatment?
You can use this treatment in the evening as part of your routine. Combination skin needs products with soothing ingredients and lightweight hydrators that help calm breakouts and balance oily shine without feeling heavy.
International Journal of Medical Sciences, 2021Experimental Dermatology, 2019
Can this treatment clog pores, cause breakouts or purging for combination skin?
This treatment is unlikely to clog pores or cause breakouts for combination skin because it is free of harsh or heavy ingredients. Its live probiotic and dendriclear help calm and clear the skin while supporting your oily areas. To best care for acne-prone combination skin, products of this type also need ingredients that provide oil control and gentle hydration.
International Journal of Medical Sciences, 2021Experimental Dermatology, 2019
What the research says
Topical application of Lactobacillus plantarum-GMNL6 enhanced collagen synthesis and SPTSSA gene expression while reducing melanin synthesis, Staphylococcus aureus biofilm, and Cutibacterium acnes proliferation, leading to clinical improvements in skin moisture, color, spots, wrinkles, UV spots, and porphyrins in human volunteers.
International Journal of Medical Sciences, 2021Topical application of live Lactobacillus reuteri DSM 17938 and its lysate reduced proinflammatory IL-6 and IL-8 in UVB-R-induced inflammation models, with live bacteria also increasing aquaporin 3 expression and exhibiting antimicrobial activity against skin pathogens.
Experimental Dermatology, 2019Topical probiotics, synbiotics, and postbiotics promote antimicrobial and anti-inflammatory properties, angiogenesis, tissue regeneration, and skin barrier restoration in preclinical wound models compared to untreated or control conditions.
Pharmaceuticals, 2025
Ingredients
Live Probiotic, Dendriclear, Acb Bio-Chelate 5pf, Mangifera Indica Leaf Extract
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.