# NEOGEN Dermalogy Real Niacinamide Serum for combination skin

**Lovi Fit: High fit for combination skin.**
Combination Skin Fit: Superior · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/uk/p/neogen-dermalogy/real-niacinamide-serum/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [NEOGEN Dermalogy](https://lovi.care/skincare/uk/brands/neogen-dermalogy)
Category: [Serums and treatments](https://lovi.care/skincare/uk/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for combination skin; a few serums fit it even better.

## Why this fit

- Excellent suitability for your combination skin, as niacinamide and arbutin effectively brighten and even your skin tone, while Zinc PCA and sodium hyaluronate regulate sebum and provide hydration.
- The inclusion of panthenol and ferulic acid further supports skin health and offers antioxidant protection, complementing the primary brightening and oil-controlling benefits.
- The formulation is safe for your skin, with no harsh ingredients that could cause irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/neogen-dermalogy/real-niacinamide-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/uk/p/neogen-dermalogy/real-niacinamide-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/uk/p/neogen-dermalogy/real-niacinamide-serum/for/combination-skin): High (this page)
- [Sensitive skin](https://lovi.care/skincare/uk/p/neogen-dermalogy/real-niacinamide-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/uk/p/neogen-dermalogy/real-niacinamide-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/uk/p/neogen-dermalogy/real-niacinamide-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/uk/p/neogen-dermalogy/real-niacinamide-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/neogen-dermalogy/real-niacinamide-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/neogen-dermalogy/real-niacinamide-serum/for/oily-acne-prone-skin): High

## Key ingredients

Niacinamide, Ferulic Acid, Zinc, Vitamin B, Arbutin

## What the research says

- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- Topical nicotinamide plus an antibacterial adhesive agent and zinc-pyrrolidone carboxylic acid combined with adapalene significantly reduced noninflammatory acne lesions by the second week of therapy compared to placebo with adapalene in patients with moderate acne vulgaris. ([The Journal of Clinical and Aesthetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32983333/))
- A topical antioxidant solution of 15% L-ascorbic acid, 1% alpha-tocopherol, and 0.5% ferulic acid provides significant photoprotection against solar-simulated UV radiation in human skin compared to its vehicle. ([Journal of the American Academy of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18603326/))
- A non-hydroquinone topical formulation (SKNB19) improved hyperpigmentation by 28.5% in patient self-assessment and 27% in independent reviewer assessment compared with 4% hydroquinone in 18 adult subjects, while showing significantly less irritation and better tolerability. ([Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/33022197/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Treatment with 14% ferulic acid and 12% l-ascorbic acid significantly reduced pigmentation and erythema while improving hydration and elasticity in 20 women with photoaged skin, with neither acid proving definitively more effective overall though ascorbic acid showed slightly greater skin lightening. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/34877760/))
- Combining fractional microneedle radiofrequency with a topical antioxidant serum significantly reduced wrinkle severity by 29.9% versus 18.0%, increased elasticity by 12.9% versus 2.3%, and improved aesthetic outcomes in 31 participants compared to radiofrequency and placebo. ([The Journal of Dermatological Treatment, 2025](https://pubmed.ncbi.nlm.nih.gov/40464749/))
- Pretreatment with a topical antioxidant mixture of vitamin C, ferulic acid, and phloretin attenuated ultraviolet-induced sunburn cell formation, thymine dimer formation, matrix metalloproteinase-9 expression, p53 protein expression, and the suppression of CD1a-expressing Langerhans cells in human skin compared to vehicle control. ([Journal of Cosmetic Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19146606/))
- Topical zinc treatment enhanced MMP-1 expression beneath the neoepidermis and metallothionein expression under the neoepidermis and in the wound bed in human epidermal wounds compared to placebo and control treatments. ([European Journal of Cell Biology, 2021](https://pubmed.ncbi.nlm.nih.gov/33485703/))
- Topical preparations containing zinc(II) complexes with glycine and histidine effectively treat acne skin by providing high antibacterial activity against C. acnes and low cytotoxicity for skin cells, with no observed irritation or allergy in healthy volunteers. ([International Journal of Molecular Sciences, 2021](https://pubmed.ncbi.nlm.nih.gov/33561977/))
- Topical copper and zinc formulations promote skin healing by exerting antimicrobial effects, modulating macrophage polarization, acting as enzyme cofactors, stimulating angiogenesis, and supporting re-epithelialization. ([Dermatology and Therapy, 2026](https://pubmed.ncbi.nlm.nih.gov/41205051/))
- Topical riboflavin photodynamic therapy showed comparable efficacy in reducing acne lesions and fewer adverse events compared with 5-aminolevulinic acid photodynamic therapy in patients with mild to moderate facial acne. ([Photodiagnosis and Photodynamic Therapy, 2025](https://pubmed.ncbi.nlm.nih.gov/39709022/))
- Topical application of niacin derivatives increased hair fullness in sixty female subjects with female pattern hair loss compared to placebo. ([Journal of Cosmetic Dermatology, 2005](https://pubmed.ncbi.nlm.nih.gov/17168873/))
- Topical myristyl nicotinate increased skin cell NAD, stratum corneum thickness, epidermal thickness, epidermal renewal, minimal erythemal dose, and barrier resistance while reducing transepidermal water loss in subjects with photodamaged skin compared to placebo. ([Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17518989/))
- Encapsulation of alpha arbutin in an optimized ethosomal gel significantly improved skin melanin reduction, moisture content, and elasticity in human volunteers compared to conventional formulations. ([Heliyon, 2023](https://pubmed.ncbi.nlm.nih.gov/37681127/))
- Combining a home-based radiofrequency device and arbutin cream reduced mMASI scores by 25.6% and melanin index by 22.8% at 8 weeks compared to baseline in 38 participants. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/39918262/))
- Polyvinyl pyrrolidone-K90/Eudragit RL100 dissolving microneedle patches loaded with alpha-arbutin and resveratrol enhanced intradermal delivery by approximately 2.6 times compared to cream and slightly decreased the melanin index in human participants without causing skin irritation. ([Biomaterials Science, 2023](https://pubmed.ncbi.nlm.nih.gov/37183632/))

## What reviewers say

Users consistently praise this serum for its ability to brighten dull complexions and fade hyperpigmentation while effectively regulating oil production. The lightweight, milky texture is widely appreciated for absorbing quickly and layering well, though the packaging is frequently criticized for accumulating crystallized product around the rim.

- Liked: Brightens skin (often mentioned)
- Liked: Fades dark spots (often mentioned)
- Liked: Hydrating & lightweight (often mentioned)
- Liked: Controls oil (sometimes noted)
- Liked: Improves texture (sometimes noted)
- Disliked: Packaging issues (sometimes noted)
- Disliked: Mild irritation (rarely noted)
- Disliked: No visible results (rarely noted)
- Disliked: Sticky texture (rarely noted)
- Disliked: Unpleasant scent (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes NEOGEN Real Niacinamide Serum a great fit for combination skin?

NEOGEN Dermalogy Real Niacinamide Serum is a great fit for your combination skin because niacinamide and arbutin effectively brighten and even your skin tone, while zinc PCA and sodium hyaluronate regulate oil and provide hydration. Panthenol and ferulic acid further support skin health and offer antioxidant protection.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### Which ingredients make this serum a good fit for combination skin?

Niacinamide and arbutin make this serum a great fit by brightening and evening out your skin tone, while zinc and sodium hyaluronate help control oil and keep your skin hydrated. Panthenol and ferulic acid also support overall skin health and provide antioxidant protection without any harsh ingredients that might cause irritation.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### What does Niacinamide do for combination skin?

Niacinamide helps balance oily areas by reducing excess shine and pore size while keeping dry patches hydrated and smooth. It also works to calm redness and even out skin tone, making it very suitable for combination skin.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### What does Ferulic Acid do for combination skin?

Ferulic acid helps protect combination skin from sun damage and everyday environmental stress while boosting the performance of vitamins C and E. For combination skin to get the best results, this ingredient needs to be paired with antioxidants and lightweight hydrators that balance oil and dry areas without clogging pores.
Sources: [Journal of the American Academy of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18603326/), [Journal of Cosmetic Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19146606/)

### Where does this serum go in a skincare routine for combination skin?

This serum goes in your evening routine after cleansing and toning, and before moisturizing. Putting treatments in the evening keeps things simple and avoids sun sensitivity.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to brighten and hydrate, followed by retinol. The gentle formulation is unlikely to irritate your skin when you combine them.

### How often should I use this serum?

This treatment serum works well in your evening routine for simplicity and extra safety around sun exposure. Some serums can also be used in the morning or twice a day once your skin adjusts to them.

### Can this serum clog pores, cause breakouts or purging for combination skin?

This serum is unlikely to clog pores or cause breakouts on your combination skin because it features ingredients that help regulate oil and maintain hydration without harsh components. Reviewers rarely mention breakouts or sticky texture with this product.
Sources: [The Journal of Clinical and Aesthetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32983333/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/uk/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/combination-skin) — Superior fit — £36.96 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/uk/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin) — Superior fit — £24.20 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/uk/p/augustinus-bader/the-serum/for/combination-skin) — Superior fit — £248.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/uk/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — £14.99 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/uk/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — £30.37 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/uk/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — £14.80 at Amazon

## Where to buy

- Amazon.co.uk: £24.20 (https://www.amazon.co.uk/dp/B0B8MVX1PS?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- Notino: £30.90 (https://www.notino.co.uk/neogen-dermalogy/real-niacinamide-15-serum-regenerating-and-brightening-serum-for-pigment-spot-correction/p-16312839/)
Prices checked 10 Oct – 6 Nov 2026.

## Ingredients

Water, Glycerin, Cetyl Ethylhexanoate, Dipropylene Glycol, 1,2-Hexanediol, Polysorbate 60, Propanediol, Bisabolol, Coco-Caprylate Caprate, Tromethamine, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Carbomer, Ethylhexylglycerin, Caprylic Capric Triglyceride, Adenosine, Xanthan Gum, Hydrogenated Lecithin, Phytosteryl Octyldodecyl Lauroyl Glutamate, Ceramide Np, Riboflavin, Arbutin, Thiamine Hcl, Panthenol, Zinc Pca, Ferulic Acid, Sodium Hyaluronate, Sodium Octenylsuccinate Starch, Houttuynia Cordata Extract, Sodium Ascorbyl Phosphate, Tocopheryl Acetate, Pyridoxine Hcl, Calendula Officinalis Extract, Artemisia Capillaris Extract, Silica
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/neogen-dermalogy/real-niacinamide-serum/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/neogen-dermalogy/real-niacinamide-serum/for/combination-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/neogen-dermalogy/real-niacinamide-serum/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/neogen-dermalogy/real-niacinamide-serum/for/combination-skin
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- Australia: https://lovi.care/skincare/au/p/neogen-dermalogy/real-niacinamide-serum/for/combination-skin
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- United Arab Emirates: https://lovi.care/skincare/ae/p/neogen-dermalogy/real-niacinamide-serum/for/combination-skin