# MEDIHEAL AGE-R for dry skin

**Lovi Fit: Average fit for dry skin.**
Dry Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/uk/p/mediheal/age-r/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [MEDIHEAL](https://lovi.care/skincare/uk/brands/mediheal)
Category: [Serums and treatments](https://lovi.care/skincare/uk/best/serums)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry skin; other serums fit it better.

## Why this fit

- Offers moderate skin firming for your dry skin due to collagen and peptides, which also provide emollient action and support barrier repair.
- While the ingredients offer general skin conditioning, they are not specifically targeted to address dryness or flakiness.
- The product is safe for your dry skin as it contains no prohibited or harsh ingredients, minimizing irritation risks.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/mediheal/age-r/for/oily-skin): Caution
- [Dry skin](https://lovi.care/skincare/uk/p/mediheal/age-r/for/dry-skin): Average (this page)
- [Combination skin](https://lovi.care/skincare/uk/p/mediheal/age-r/for/combination-skin): Low
- [Sensitive skin](https://lovi.care/skincare/uk/p/mediheal/age-r/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/uk/p/mediheal/age-r/for/acne-prone-skin): Low
- [Skin with dark spots](https://lovi.care/skincare/uk/p/mediheal/age-r/for/dark-spots): Low
- [Mature skin](https://lovi.care/skincare/uk/p/mediheal/age-r/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/mediheal/age-r/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/mediheal/age-r/for/oily-acne-prone-skin): Caution

## Key ingredients

Glutathione, Collagen, Peptides

## What the research says

- Both oral and topical collagen supplements help delay the skin aging process by improving moisture, elasticity, and hydration, with no differences arising between the two types of collagen. ([Dermatology Practical & Conceptual, 2022](https://pubmed.ncbi.nlm.nih.gov/35223163/))
- The use of cosmetic products containing collagen or its peptides improves the general condition of the skin, reduces wrinkle depth, improves hydration and density, reduces transepithelial water loss, and delays the aging process, while oral bioactive collagen peptides also reduce nail breakage. ([Current Issues in Molecular Biology, 2024](https://pubmed.ncbi.nlm.nih.gov/38534748/))
- Bioactive glycyrrhizic acid and oxymatrine ionic liquid self-assembled nanomicelles significantly promoted the transdermal permeation, subcutaneous retention, and anti-photoaging efficacy of palmitoyl pentapeptide-4 in cellular and animal models compared to unformulated peptide. ([Advanced Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39783908/))
- Glutathione amino acid precursors effectively increase cellular glutathione levels, reducing oxidative stress, ATP depletion, and DNA damage in human keratinocytes, clinical subjects, and ex vivo skin compared to controls. ([Journal of the European Academy of Dermatology and Venereology, 2024](https://pubmed.ncbi.nlm.nih.gov/38189670/))
- Topical oxidized glutathione significantly decreases the skin melanin index and improves moisture content, smoothness, wrinkle formation, and elasticity compared to placebo in healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25378941/))
- Topical glutathione improves hyperpigmentation, reduces ultraviolet-induced erythema and wrinkles, decreases transepidermal water loss, and enhances antioxidant capacity. ([The Journal of Clinical and Aesthetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41416233/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))

## Why other serums fit dry skin better

- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))

## What reviewers say

Based on a very large amount of data, users frequently achieve a 'glass skin' appearance and improved facial contouring, with many reporting enhanced product absorption and a more radiant complexion. While effective for dullness and mild sagging, results are highly dependent on consistent daily use, which some users find difficult to maintain. The device is also noted for improving skin texture and reducing pore visibility.

- Liked: Enhanced absorption (mostly mentioned)
- Liked: Glass skin glow (often mentioned)
- Disliked: Time-consuming routine (often mentioned)
- Liked: Improved texture (sometimes noted)
- Liked: Visible lifting (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Unpleasant sensation (sometimes noted)
- Disliked: Potential irritation (rarely noted)

## How to apply

- Apply this serum PM, starting 3×/week and working up to daily use as your skin adjusts.
- Place the serum after cleansing and toner, but right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on slightly damp skin to help lock in extra moisture.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Mediheal AGE-R work for dry skin?

Mediheal AGE-R works reasonably well for dry skin, offering moderate firming and general conditioning with collagen and peptides, though it lacks ingredients specifically targeted at dryness and flakiness. A treatment for dry skin needs richly hydrating and soothing ingredients like propolis, ceramides, niacinamide, or bifida fermentation that specifically target hydration and skin barrier support.
Sources: [Dermatology Practical & Conceptual, 2022](https://pubmed.ncbi.nlm.nih.gov/35223163/), [Current Issues in Molecular Biology, 2024](https://pubmed.ncbi.nlm.nih.gov/38534748/)

### Which ingredients make this cream a good fit for dry skin?

Collagen and peptides make this cream a fit for your dry skin because they help firm the skin and support barrier repair, though this skin needs ingredients that specifically target dryness and flakiness like propolis, niacinamide, ceramides, or vitamin C.
Sources: [Dermatology Practical & Conceptual, 2022](https://pubmed.ncbi.nlm.nih.gov/35223163/), [Current Issues in Molecular Biology, 2024](https://pubmed.ncbi.nlm.nih.gov/38534748/)

### What does Glutathione do for dry skin?

Glutathione helps dry skin by improving moisture levels and smoothness while keeping the skin barrier strong against daily stress. Topical application of glutathione may also reduce water loss through the skin, helping your face feel softer and more hydrated.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25378941/), [The Journal of Clinical and Aesthetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41416233/)

### What does Collagen do for dry skin?

Collagen helps dry skin by boosting hydration, improving moisture levels, and supporting the skin barrier. This type of product may reduce water loss and keep skin feeling soft and smooth over time.
Sources: [Current Issues in Molecular Biology, 2024](https://pubmed.ncbi.nlm.nih.gov/38534748/), [International Journal of Molecular Sciences, 2021](https://pubmed.ncbi.nlm.nih.gov/34638528/)

### Where does it go in a skincare routine for dry skin?

This treatment goes in the evening routine after cleansing and before moisturizing, though products of this type for dry skin work best when they also provide deep moisture and target flakiness using ingredients like hyaluronic acid or ceramides.

### Can I use this cream with retinol, and in what order?

You can use this treatment with retinol, applying retinol first and following with this product to keep your skin safe. This treatment offers moderate firming with collagen and peptides, but to properly care for dry skin it needs richer moisturizing ingredients that directly target dryness and flakiness.

### How often should I use it?

Use this treatment in your evening routine, applying it after cleansing and before moisturizing. While it helps firm and condition your dry skin, a product for this skin needs rich hydrating and moisturizing ingredients to properly target dryness and flakiness.
Sources: [Dermatology Practical & Conceptual, 2022](https://pubmed.ncbi.nlm.nih.gov/35223163/), [Current Issues in Molecular Biology, 2024](https://pubmed.ncbi.nlm.nih.gov/38534748/)

### Can it clog pores, cause breakouts or purging for dry skin?

It is unlikely to clog pores or cause breakouts for dry skin since it has a safe formula with a low risk of irritation. However, because it is not specifically targeted to address dryness, a product for dry skin of this type needs rich moisturizing ingredients like ceramides or hyaluronic acid to properly comfort dry areas.

## Alternatives for dry skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/uk/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/dry-skin) — Superior fit — £36.96 at Amazon
- [KraveBeauty Great Barrier Relief](https://lovi.care/skincare/uk/p/kravebeauty/great-barrier-relief/for/dry-skin) — Superior fit — £32.95 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/uk/p/augustinus-bader/the-serum/for/dry-skin) — Superior fit — £248.00 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/uk/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — £8.29 at Amazon
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/uk/p/dear-klairs/supple-preparation-unscented-toner/for/dry-skin) — Superior fit — £11.49 at Amazon
- Moisturizer: [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/uk/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/dry-skin) — Superior fit — £14.74 at Amazon

## Where to buy

No store in United Kingdom has a checked price for this product, so the page shows none.

## Ingredients

Glutathione, Collagen, Peptides
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/mediheal/age-r/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/mediheal/age-r/for/dry-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/mediheal/age-r/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/mediheal/age-r/for/dry-skin
- France: https://lovi.care/skincare/fr/p/mediheal/age-r/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/mediheal/age-r/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/mediheal/age-r/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/mediheal/age-r/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/mediheal/age-r/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/mediheal/age-r/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/mediheal/age-r/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/mediheal/age-r/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/mediheal/age-r/for/dry-skin