Medicube PDRN Pink Peptide Ampoule for dry sensitive skin
Salmon Pdrn
Salmon Collagen Complex
UbiquinoneAverage
- HighDry Skin Fit
- AverageEffectiveness
- HighSafety
Works for dry sensitive skin; other moisturizers fit it better.
This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate benefits for your dry and sensitive skin, as Hyaluronic Acid and Peptide Complex provide excellent hydration and improve elasticity, which are supportive for dry or flaky skin.
- The Salmon Collagen Complex further aids in providing emollient actions beneficial for dry skin.
- The product is safe for your skin due to the absence of prohibited or harsh ingredients, posing no risk of irritation.
How to apply
- Could be used as part of your AM or PM routine. Start using this moisturizer 3 times a week and move to daily use if your dry skin tolerates it well.
- Apply this moisturizer after cleansing and toner in the morning, or after your serum in the evening. Always pair it with SPF in the morning.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing it harshly to protect your sensitive skin.
- Apply the moisturizer on slightly damp skin to help with hydration absorption. This also works well for dry and flaky skin types.
- Do a patch test before your first use. Avoid the eye area to prevent any irritation.
People Say
★4.7Overall rating based on 2.5k+ reviewsBased on a very large amount of data, users consistently report that this ampoule delivers a "glass skin" effect, providing deep hydration and a noticeable plumping effect that benefits dry and aging skin. While it is widely praised for smoothing texture and soothing sensitive skin, results regarding blemish fading are mixed and take longer to appear.
Highlights
Deep hydration Mostly Mentioned
- “skin feels bouncier”
- “deeply moisturized from within”
- “plump and radiant”
- “eliminated deep dryness”
Radiant glow Mostly Mentioned
- “glass skin glow”
- “healthy dewy look”
- “complexion looks clearer”
- “natural inner glow”
Fast absorption Often Mentioned
- “absorbs quickly”
- “no greasy residue”
- “lightweight formula”
- “glides onto skin beautifully”
Noticeable fragrance Sometimes Noted
- “strong rosy scent”
- “smell isn't my thing”
- “wish it was fragrance-free”
- “scent is polarizing”
Small volume Sometimes Noted
- “runs out quickly”
- “30ml is too small”
- “pricey for the size”
- “wish they offered a larger version”
Soothing and gentle Sometimes Noted
- “no irritation”
- “calmed redness”
- “good for sensitive skin”
- “gentle and soothing”
Minor breakouts Rarely Noted
- “small pimple appeared”
- “caused blemishes on chin”
- “broke me out slightly”
- “congestion on forehead”
Slight stickiness Rarely Noted
- “tacky film”
- “slight sticky feeling”
- “residue left behind”
- “hair sticks to face”
Sources: lovi.care, oliveyoung.com, yesstyle.com, hwahae.co.kr, amazon.co.uk, youtube.com, and more
Questions and answers
How well does medicube PDRN Pink Peptide Ampoule work for dry sensitive skin?
It works moderately well for your dry sensitive skin, as hyaluronic acid and peptide complex provide good hydration and improve elasticity to help with dry flakes, while being safe and unlikely to cause irritation. To fit this skin type best, a moisturizing treatment needs multiple forms of hyaluronic acid, pro vitamin B5, and ceramides for intense hydration, moisture retention, and strong barrier support.
Dermatologic Therapy, 2022International Journal of Cosmetic Science, 2005
Which ingredients make this serum a good fit for dry sensitive skin?
Hyaluronic acid, peptide complex, and salmon collagen complex make this serum a good fit for dry sensitive skin by providing hydration and softening benefits. A product of this type needs multiple forms of hyaluronic acid, pro vitamin B5, and ceramides to intensely hydrate, nourish, and strengthen the skin barrier.
What does Salmon Pdrn do for dry sensitive skin?
Salmon PDRN helps calm dry sensitive skin by reducing inflammation and supporting natural tissue repair. It may also improve skin barrier function and boost cell renewal for a smoother and more resilient feel.
What does Salmon Collagen do for dry sensitive skin?
Salmon collagen helps soothe dry sensitive skin by providing a gentle touch of moisture. It works to keep your skin feeling soft and smooth without causing irritation.
Where does this serum go in a skincare routine for dry sensitive skin?
This treatment goes in the evening routine after your soothing toner and before your moisturizer. Putting it in the evening helps keep things simple and adds extra safety around sun exposure.
Can I use this serum with retinol, and in what order?
You can use this treatment alongside retinol by applying the treatment first and following with your retinol. Because your dry and sensitive skin needs products that provide deep moisture and strengthen the skin barrier with ingredients like ceramides and nourishing plant oils, this combination works best when your routine focuses on gentle hydration.
How often should I use this serum?
You can use this treatment in your evening routine, as this serum is safe for your skin and poses no risk of irritation. A dry and sensitive skin type needs a moisturizing treatment with rich soothing oils and gentle hydrating ingredients to lock in moisture and comfort dry areas.
Can this serum clog pores, cause breakouts or purging for dry sensitive skin?
This serum is unlikely to cause breakouts, clogged pores, or purging on dry sensitive skin due to its safe ingredients and lack of harsh components. A product for this skin needs gentle hydrators and soothing ingredients like hyaluronic acid and peptides to keep skin smooth and calm.
Can I use this serum around the eyes or on my body?
You can use this moisturizing treatment around the eyes and on your body, as it has a safe makeup that poses no risk of irritation. Hyaluronic acid, peptide complex, and salmon collagen complex help hydrate and smooth thin or dry skin in these areas. To fit your dry and sensitive skin even better, a product of this type needs rich, soothing oils and barrier-supporting lipids.
Is this serum fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
Topical palmitoyl pentapeptide (pal-KTTKS) provided significant improvement versus placebo control in the reduction of wrinkles and fine lines in Caucasian female subjects.
International Journal of Cosmetic Science, 2005Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone.
Dermatologic Therapy, 2022Optimized transfersomes loaded with epigallocatechin-3-gallate and hyaluronic acid increased cell viability while reducing lipid peroxidation, intracellular ROS, and MMP expression in HaCaT cells, and exhibited higher skin permeation and deposition compared to plain EGCG.
Drug Delivery, 2017Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers.
Marine Drugs, 2023Topical application of Low-Peony PDRN enhanced barrier recovery and improved periorbital skin elasticity in human subjects.
International Journal of Molecular Sciences, 2025Polydeoxyribonucleotide promotes skin regeneration by increasing ERK phosphorylation, collagen accumulation, and cell proliferation and migration in fibroblasts while inhibiting ERK phosphorylation and inflammatory cytokine expression in keratinocytes.
Molecular Medicine Reports, 2023A topical mixture of polydeoxyribonucleotide, vitamin C, and niacinamide delivered via a microneedling therapy system decreased skin pigmentation and increased skin elasticity by attenuating melanogenesis and the destruction of collagen and elastin fibers in a UV-B-radiated animal model.
Molecules, 2022Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris.
Journal of Cosmetic Dermatology, 2022Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks.
International Journal of Molecular Sciences, 2022Marine sponge collagen extract formulations increased skin lipids significantly while having no noticeable influence on skin surface pH and only slightly increasing skin hydration.
European Journal of Pharmaceutics and Biopharmaceutics, 2002Topical application of CoQ10 improves mitochondrial function in aging skin in vivo, combating cellular signs of aging caused by an age-dependent shift to a functionally anaerobic energy metabolism.
BioFactors, 2008Encapsulating coenzyme Q10 in lipid nanoparticles for topical use improves skin compatibility, protects against degradation, increases skin penetration, and provides controlled release to counteract aging effects.
Colloids and Surfaces. B, Biointerfaces, 2023Review of topical administration of carotenoids and coenzyme Q10 loaded in lipid nanoparticles highlights their improved bioavailability, chemical stability, skin absorption, and photoprotective effects.
Antioxidants, 2021
Ingredients
Salmon Pdrn, Salmon Collagen Complex, Ubiquinone, Ocimum Tenuiflorum, Hyaluronic Acid, Niacinamide, Curcuma Longa Root Extract, Adenosine, Ocimum Sanctum Leaf Extract, Peptide Complex, Rose Pdrn Extract Rosa Damascena Sodium Dna Extract
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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