# Medicube PDRN Pink Collagen Gel Mask for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/uk/p/medicube/pdrn-pink-collagen-gel-mask/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [Medicube](https://lovi.care/skincare/uk/brands/medicube)
Category: [Face masks](https://lovi.care/skincare/uk/best/face-masks)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other nourishing masks fit it better.

## Why this fit

- Offers moderate nourishing benefits for your normal skin, as sodium DNA and hydrolyzed collagen hydrate and improve elasticity, while niacinamide provides general soothing effects for redness and irritation.
- The ingredients are highly suitable for normal skin and offer barrier repair and melanogenesis regulation, though they are not specialized enough to directly address your sensitivity concerns.
- The product is safe for your sensitive skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/medicube/pdrn-pink-collagen-gel-mask/for/oily-skin): Low
- [Dry skin](https://lovi.care/skincare/uk/p/medicube/pdrn-pink-collagen-gel-mask/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/uk/p/medicube/pdrn-pink-collagen-gel-mask/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/uk/p/medicube/pdrn-pink-collagen-gel-mask/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/uk/p/medicube/pdrn-pink-collagen-gel-mask/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/uk/p/medicube/pdrn-pink-collagen-gel-mask/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/uk/p/medicube/pdrn-pink-collagen-gel-mask/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/medicube/pdrn-pink-collagen-gel-mask/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/medicube/pdrn-pink-collagen-gel-mask/for/oily-acne-prone-skin): Average

## Key ingredients

Sodium Dna, Niacinamide, Hydrolyzed Collagen

## What the research says

- Topical application of Low-Peony PDRN enhanced barrier recovery and improved periorbital skin elasticity in human subjects. ([International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/41516097/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- Topical treatment of nicotinamide, alone or in combination with other active ingredients, reduces the progression of skin aging and hyperpigmentation in clinical trials while being well tolerated. ([Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/))
- Polydeoxyribonucleotide promotes skin regeneration by increasing ERK phosphorylation, collagen accumulation, and cell proliferation and migration in fibroblasts while inhibiting ERK phosphorylation and inflammatory cytokine expression in keratinocytes. ([Molecular Medicine Reports, 2023](https://pubmed.ncbi.nlm.nih.gov/37350391/))
- A topical mixture of polydeoxyribonucleotide, vitamin C, and niacinamide delivered via a microneedling therapy system decreased skin pigmentation and increased skin elasticity by attenuating melanogenesis and the destruction of collagen and elastin fibers in a UV-B-radiated animal model. ([Molecules, 2022](https://pubmed.ncbi.nlm.nih.gov/35209068/))
- Polydeoxyribonucleotide treatment induces mitochondrial biogenesis while reducing melanin biosynthesis, tyrosinase activity, MITF expression, elastase activity, and MMP-1 gene expression in cultured skin cells. ([Applied Biochemistry and Biotechnology, 2020](https://pubmed.ncbi.nlm.nih.gov/31811642/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical 2% niacinamide significantly decreased sebum excretion rate in Japanese individuals and casual sebum levels in Caucasian individuals compared to placebo or baseline. ([Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))

## Why other nourishing masks fit sensitive skin better

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Application of Galactomyces ferment filtrate skin care formula significantly reduced the net values and daily fluctuation of facial pore area, roughness, and redness in young Japanese women. ([Journal of Clinical Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34198790/))

## What reviewers say

Based on a very large amount of data, users with dry, dull, or aging skin frequently praise this mask for delivering a "glass skin" glow and deep hydration that plumps fine lines and revitalizes the complexion. The cooling effect and post-facial radiance are highly rated by many users. Some users find the application messy, the price point high, and the required wear time inconvenient.

- Liked: Hydration and glow (mostly mentioned)
- Liked: Soothing and cooling (often mentioned)
- Disliked: Expensive product (often mentioned)
- Disliked: Messy application (often mentioned)
- Liked: Good adherence (sometimes noted)
- Liked: Plumping effect (sometimes noted)
- Disliked: Poor fit (sometimes noted)
- Disliked: Skin irritation (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start by using the sheet mask 3 times a week and increase if your skin feels good.
- Apply the sheet mask right after cleansing and toning, but always before your daily moisturizer or SPF.
- Unfold the sheet mask and gently press it onto your face, avoiding any harsh rubbing. Leave it on for ten to fifteen minutes.
- For sensitive skin, apply the sheet mask on completely dry skin to ensure better comfort and tolerance.
- Always avoid the delicate eye area and do a quick patch test before your very first use.
- Video: https://storage.pora.ai/cf9cbc1593b43309df7ca9cfe4fbbdae.mp4

## Questions and answers

### How well does medicube Pink Collagen Gel Mask work for sensitive skin?

The medicube PDRN Pink Collagen Gel Mask works reasonably well for sensitive skin, though other products fit it better because its ingredients are not specialized enough to directly address your sensitivity concerns. A nourishing mask for sensitive skin needs effective soothing ingredients that address redness and irritation without posing any risk of irritation.
Sources: [International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/41516097/)

### Which ingredients make this mask a good fit for sensitive skin?

Niacinamide, sodium DNA, and hydrolyzed collagen make this mask a good fit by providing soothing effects for redness and irritation while hydrating the skin. Although it is safe, sensitive skin often needs products that feature specialized soothing ingredients to address sensitivity concerns directly.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/41516097/)

### What does Sodium DNA do for sensitive skin?

Sodium DNA helps calm sensitive skin by supporting barrier recovery and making skin feel more comfortable. It is unlikely to cause irritation and may improve overall skin texture.
Sources: [International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/41516097/)

### What does Niacinamide do for sensitive skin?

Niacinamide helps calm sensitive skin by strengthening the skin barrier and reducing redness and irritation. It is very well tolerated and may improve overall comfort and resilience with regular use.
Sources: [Cutis, 2005](https://pubmed.ncbi.nlm.nih.gov/16209160/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### Where does this mask go in a skincare routine for sensitive skin?

This mask goes into the weekly routine for sensitive skin, used after cleansing and before treatments and moisturizers. It is safe for sensitive skin because it avoids harsh ingredients, but sensitive skin needs a product with specialized calming and soothing ingredients to directly address redness and reactivity.

### Can I use this mask with retinol, and in what order?

You can use this mask in your weekly routine, keeping it on a separate night from your retinol treatment to avoid overwhelming your skin. This mask helps hydrate and calm redness, while a separate soothing moisturizer used with your retinol can better protect sensitive skin.

### How often should I use this mask?

You can use this nourishing mask once a week as part of your routine. This product is safe for sensitive skin due to the absence of harsh ingredients, though a mask of this type also needs specialized soothing and barrier-repairing ingredients to fully address sensitivity concerns.

### Can this mask clog pores, cause breakouts or purging for sensitive skin?

This mask is unlikely to clog pores or cause breakouts for sensitive skin due to the absence of harsh ingredients, though a poor fit is a common complaint. A product of this type needs soothing and calming ingredients to truly comfort sensitive skin.

## Alternatives for sensitive skin

- [I'm From Mugwort Mask](https://lovi.care/skincare/uk/p/i-m-from/mugwort-mask/for/sensitive-skin) — High fit — £13.49 at Amazon
- [Tatcha The Violet-C Radiance Mask](https://lovi.care/skincare/uk/p/tatcha/violet-c-radiance-mask/for/sensitive-skin) — High fit — £84.80 at Amazon
- [SK-II Facial Treatment Mask](https://lovi.care/skincare/uk/p/sk-ii/facial-treatment-mask/for/sensitive-skin) — Average fit — £63.63 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/uk/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — £14.99 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/uk/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — £17.91 at Amazon
- Moisturizer with Sun Protection: [Clinique Mineral Sunscreen Fluid for Face SPF 50](https://lovi.care/skincare/uk/p/clinique/broad-spectrum-spf-50-mineral-sunscreen-fluid-for-face/for/sensitive-skin) — Superior fit — £21.00 at Amazon

## Where to buy

- Amazon.co.uk: £4.70 (https://www.amazon.co.uk/dp/B0DBF52CLJ?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- Notino: £18.50 (https://www.notino.co.uk/medicube/pdrn-pink-collagen-gel-mask-lifting-and-firming-mask-with-collagen/p-16325844/)
Prices checked 10 Oct – 6 Nov 2026.

## Ingredients

Sodium Dna, Niacinamide, Hydrolyzed Collagen
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medicube/pdrn-pink-collagen-gel-mask/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medicube/pdrn-pink-collagen-gel-mask/for/sensitive-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/medicube/pdrn-pink-collagen-gel-mask/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/medicube/pdrn-pink-collagen-gel-mask/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/medicube/pdrn-pink-collagen-gel-mask/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/medicube/pdrn-pink-collagen-gel-mask/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/medicube/pdrn-pink-collagen-gel-mask/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/medicube/pdrn-pink-collagen-gel-mask/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/medicube/pdrn-pink-collagen-gel-mask/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/medicube/pdrn-pink-collagen-gel-mask/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/medicube/pdrn-pink-collagen-gel-mask/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medicube/pdrn-pink-collagen-gel-mask/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medicube/pdrn-pink-collagen-gel-mask/for/sensitive-skin