# Medicube PDRN PINK CICA SOOTHING TONER for acne-prone skin

**Lovi Fit: High fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/uk/p/medicube/pdrn-pink-cica-soothing-toner/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [Medicube](https://lovi.care/skincare/uk/brands/medicube)
Category: [Toners](https://lovi.care/skincare/uk/best/toners)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for acne-prone skin; a few toners fit it even better.

## Why this fit

- Offers excellent soothing and calming effects for your combination skin, as Centella Asiatica Extract and Allantoin work to reduce redness and irritation, while Hyaluronic Acid provides essential hydration.
- The inclusion of PDRN further supports regenerative properties beneficial for managing acne and blemishes.
- The product is safe for your combination skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/medicube/pdrn-pink-cica-soothing-toner/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/uk/p/medicube/pdrn-pink-cica-soothing-toner/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/uk/p/medicube/pdrn-pink-cica-soothing-toner/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/uk/p/medicube/pdrn-pink-cica-soothing-toner/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/uk/p/medicube/pdrn-pink-cica-soothing-toner/for/acne-prone-skin): High (this page)
- [Skin with dark spots](https://lovi.care/skincare/uk/p/medicube/pdrn-pink-cica-soothing-toner/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/uk/p/medicube/pdrn-pink-cica-soothing-toner/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/medicube/pdrn-pink-cica-soothing-toner/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/medicube/pdrn-pink-cica-soothing-toner/for/oily-acne-prone-skin): Average

## Key ingredients

Centella Asiatica Extract, Hyaluronic Acid, Pdrn Polydeoxyribonucleotide

## What the research says

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- Topical application of Low-Peony PDRN enhanced barrier recovery and improved periorbital skin elasticity in human subjects. ([International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/41516097/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Polydeoxyribonucleotide promotes skin regeneration by increasing ERK phosphorylation, collagen accumulation, and cell proliferation and migration in fibroblasts while inhibiting ERK phosphorylation and inflammatory cytokine expression in keratinocytes. ([Molecular Medicine Reports, 2023](https://pubmed.ncbi.nlm.nih.gov/37350391/))
- A topical mixture of polydeoxyribonucleotide, vitamin C, and niacinamide delivered via a microneedling therapy system decreased skin pigmentation and increased skin elasticity by attenuating melanogenesis and the destruction of collagen and elastin fibers in a UV-B-radiated animal model. ([Molecules, 2022](https://pubmed.ncbi.nlm.nih.gov/35209068/))
- Plant-derived polydeoxyribonucleotide from Panax ginseng promoted skin wound healing and enhanced the skin barrier by stimulating keratinocyte and fibroblast proliferation in skin cells and an artificial skin model. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37959659/))

## What reviewers say

Users with sensitive and acne-prone skin frequently praise this toner for its immediate soothing and redness-reducing effects, often noting a brighter, more even complexion after consistent use. The lightweight, non-sticky texture is a popular choice for oily and combination skin, though some users with dry skin report it lacks sufficient hydration on its own.

- Liked: Lightweight texture (mostly mentioned)
- Liked: Soothing and calming (often mentioned)
- Liked: Barrier support (sometimes noted)
- Liked: Brightening and glow (sometimes noted)
- Disliked: Not hydrating enough (sometimes noted)
- Disliked: Average results (rarely noted)
- Disliked: Expensive for value (rarely noted)
- Disliked: Sensory complaints (rarely noted)

## How to apply

- Use your soothing toner AM and PM daily to help keep breakouts under control.
- Apply this soothing toner right after cleansing and before your moisturizer or SPF.
- Gently press 2-3 drops of the soothing toner into your skin and let it absorb.
- Pat the soothing toner onto clean, slightly damp skin for the best absorption.
- Always do a patch test before first use and avoid getting the soothing toner in your eyes.
- Video: https://storage.pora.ai/25abe7eb181ba53153fd15de2058c2a9.mp4

## Questions and answers

### What makes medicube PDRN Pink Cica Soothing Toner a great fit for acne-prone skin?

This toner is a great fit because Centella Asiatica Extract and Allantoin help calm redness and irritation, while Hyaluronic Acid keeps acne-prone skin hydrated without harsh ingredients. PDRN also supports skin recovery and helps manage blemishes safely.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### Which ingredients make this toner a good fit for acne-prone skin?

Centella Asiatica extract and allantoin help calm redness and irritation on acne-prone skin, while hyaluronic acid keeps it hydrated without feeling heavy. PDRN also supports skin healing and helps manage blemishes safely.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### What does Centella Asiatica Extract do for acne-prone skin?

Centella asiatica extract helps calm angry skin, reduces redness, and supports healing for breakouts. It is unlikely to cause irritation and may improve overall skin clarity when used consistently.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/)

### What does Hyaluronic Acid do for acne-prone skin?

Hyaluronic acid helps acne-prone skin by soothing irritation, calming redness, and keeping the skin balanced without clogging pores. When combined with targeted ingredients like zinc oxide, it may also help reduce breakouts.
Sources: [Biomedicines, 2025](https://pubmed.ncbi.nlm.nih.gov/41007718/), [Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/)

### Where does this toner go in a skincare routine for acne-prone skin?

This soothing toner goes in your morning routine right after cleansing and before your moisturizer. It helps calm redness and irritation while giving your skin essential hydration.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/)

### Can I use this toner with retinol, and in what order?

You can use this toner with retinol by applying the toner first to hydrate your skin before adding your retinol treatment. This approach helps calm redness and supports skin healing while reducing the likelihood of irritation from your routine.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### How often should I use this toner?

You can use this toner daily in your morning routine as a hydrating step after cleansing. It helps calm redness and supports skin healing without irritation.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/)

### Can this toner clog pores, cause breakouts or purging for acne-prone skin?

This toner is a great fit for acne-prone skin and is unlikely to clog pores or cause breakouts, as it is free of harsh ingredients and uses Centella Asiatica Extract and Allantoin to help calm redness and irritation. It also includes Pdrn Polydeoxyribonucleotide to support skin recovery.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### Is this toner fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [Medicube Super Cica Pad](https://lovi.care/skincare/uk/p/medicube/super-cica-pad/for/acne-prone-skin) — Superior fit — £29.50 at Amazon
- [1004 Skin Madagascar Centella Toning Toner](https://lovi.care/skincare/uk/p/1004-skin/madagascar-centella-toning-toner/for/acne-prone-skin) — Superior fit — £14.19 at Amazon
- [TIRTIR Milk Skin](https://lovi.care/skincare/uk/p/tirtir/milk-skin/for/acne-prone-skin) — Superior fit — £11.00 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/uk/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — £8.13 at Amazon
- Moisturizer: [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/uk/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — £11.90 at Amazon
- SPF: [d'Alba Piedmont Waterfull Mild Sunscreen](https://lovi.care/skincare/uk/p/d-alba/piedmont-waterfull-mild-sunscreen/for/acne-prone-skin) — Superior fit — £14.00 at Amazon

## Where to buy

- Notino: £20.50 (https://www.notino.co.uk/medicube/pdrn-pink-cica-soothing-toner-brightening-facial-toner-with-firming-effect/p-16329865/)
- Lookfantastic: £24.00 (https://www.lookfantastic.com/p/medicube-pdrn-pink-cica-soothing-toner-250ml/17753009/)
Prices checked 10 Oct – 17 Oct 2026.

## Ingredients

Water, Glycerin, Centella Asiatica Extract, Hyaluronic Acid, Pdrn Polydeoxyribonucleotide, Rosa Damascena Flower Water, Butylene Glycol, 1,2-Hexanediol, Allantoin, Panthenol, Betaine, Dipropylene Glycol, Ethylhexylglycerin, Disodium Edta
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medicube/pdrn-pink-cica-soothing-toner/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medicube/pdrn-pink-cica-soothing-toner/for/acne-prone-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/medicube/pdrn-pink-cica-soothing-toner/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/medicube/pdrn-pink-cica-soothing-toner/for/acne-prone-skin
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