# Medicube Deep Vita C Pad for mature skin

**Lovi Fit: Average fit for mature skin.**
Normal Skin Fit: Average · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/uk/p/medicube/deep-vita-c-pad/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [Medicube](https://lovi.care/skincare/uk/brands/medicube)
Category: [Serums and treatments](https://lovi.care/skincare/uk/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for mature skin; other serums fit it better.

## Why this fit

- Offers moderate suitability for normal skin as 3-O-Ethyl Ascorbic Acid and Niacinamide provide antioxidant activity and seboregulation, but it lacks sufficient humectant and emollient ingredients for optimal hydration.
- The presence of Palmitoyl Tripeptide-5 and Adenosine offers relevant benefits for wrinkles and fine lines by supporting collagen production and skin elasticity.
- The safety profile is excellent, with no risks of irritation for your normal skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/medicube/deep-vita-c-pad/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/uk/p/medicube/deep-vita-c-pad/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/uk/p/medicube/deep-vita-c-pad/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/uk/p/medicube/deep-vita-c-pad/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/uk/p/medicube/deep-vita-c-pad/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/uk/p/medicube/deep-vita-c-pad/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/uk/p/medicube/deep-vita-c-pad/for/mature-skin): Average (this page)
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/medicube/deep-vita-c-pad/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/medicube/deep-vita-c-pad/for/oily-acne-prone-skin): High

## Key ingredients

3-O-Ethyl Ascorbic Acid, Niacinamide, Sodium Hyaluronate, Vitamin Water, Adenosine

## What the research says

- A multi-component dissolving microneedle patch loaded with glabridin, 3-O-ethyl-L-ascorbic acid, and tranexamic acid effectively reduced chloasma and age spots while demonstrating safety in clinical evaluation, alongside significant antioxidant, anti-tyrosinase, and melanin-reduction effects in vitro and in vivo. ([Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37571190/))
- Adenosine-loaded dissolving microneedle patches showed similar or better efficacy on skin wrinkles, dermal density, elasticity, and hydration compared to adenosine cream in 22 female subjects. ([International Journal of Cosmetic Science, 2018](https://pubmed.ncbi.nlm.nih.gov/29574973/))
- Horse oil-spread and adenosine-loaded dissolving microneedle patches significantly improved skin elasticity, hydration, dermal density, and wrinkles compared with adenosine-loaded dissolving microneedle patches in 20 women without causing adverse events. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30160014/))
- Topical application of a disodium adenosine monophosphate-based formulation reduced wrinkles and hyperpigmentation while improving hydration, barrier function, skin lifting, and epidermal turnover in female participants. ([International Journal of Molecular Sciences, 2026](https://pubmed.ncbi.nlm.nih.gov/42278371/))
- Topical treatment of nicotinamide, alone or in combination with other active ingredients, reduces the progression of skin aging and hyperpigmentation in clinical trials while being well tolerated. ([Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical adenosine treatment significantly increased the anagen hair growth rate and thick hair rate compared to placebo in Japanese women with female pattern hair loss over 12 months. ([The Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19239555/))
- Adenosine and cordycepin stimulate the Wnt/beta-catenin signaling pathway through adenosine receptor and PKA activation, promoting cell proliferation, migration, and growth factor secretion in cultured dermal fibroblasts. ([International Journal of Molecular Sciences, 2021](https://pubmed.ncbi.nlm.nih.gov/34070360/))
- Adenosine treatment of dermal papilla cells upregulates fibroblast growth factor-7 expression via the A2b adenosine receptor and intracellular cAMP signaling, and fibroblast growth factor-7 significantly stimulates hair fiber elongation in human scalp hair follicle organ cultures. ([The Journal of Investigative Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17301835/))

## What reviewers say

Users report that these pads effectively brighten dull complexions and fade acne scars within weeks. The pads are praised for delivering a glow and gentle exfoliation, making them suitable for most skin types, though sensitive users should be cautious. Some users note a sticky finish and potential for tingling upon application.

- Liked: Brightens & Fades Spots (mostly mentioned)
- Liked: Hydrating & Glowy (often mentioned)
- Liked: Convenient & Hygienic (sometimes noted)
- Liked: Fast Results (sometimes noted)
- Liked: Gentle Exfoliation (sometimes noted)
- Disliked: Leaky packaging (sometimes noted)
- Disliked: Sticky finish (sometimes noted)
- Disliked: Pricey (rarely noted)
- Disliked: Scent (rarely noted)
- Disliked: Tingling sensation (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does the Medicube Deep Vita C Pad work for mature skin?

This product works moderately well for mature skin because it helps smooth out fine lines and wrinkles, but a treatment of this type needs more deep hydrating ingredients to keep this skin type properly moisturized.
Sources: [International Journal of Cosmetic Science, 2018](https://pubmed.ncbi.nlm.nih.gov/29574973/), [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30160014/)

### Which ingredients make this pad a good fit for mature skin?

This pad fits mature skin well because it contains Palmitoyl Tripeptide-5 and Adenosine, which help smooth fine lines and support elasticity. However, because this is an average fit, a product of this type needs richer hydrating and softening ingredients to give mature skin optimal moisture.
Sources: [International Journal of Cosmetic Science, 2018](https://pubmed.ncbi.nlm.nih.gov/29574973/), [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30160014/)

### What does 3-O-Ethyl Ascorbic Acid do for mature skin?

3-O-Ethyl Ascorbic Acid helps fade dark spots, reduces signs of aging, and supports collagen production to keep mature skin looking smooth and firm. It also provides antioxidant protection to shield the skin from daily environmental stress and sun damage.
Sources: [International Journal of Biological Macromolecules, 2026](https://pubmed.ncbi.nlm.nih.gov/41628877/), [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37571190/)

### What does Niacinamide do for mature skin?

Niacinamide helps mature skin by smoothing out fine lines and wrinkles, reducing dark spots, and improving overall skin elasticity. It is also very well tolerated and supports a strong skin barrier to keep skin looking healthy.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### Where does this pad go in a skincare routine for mature skin?

This pad goes in your evening routine as a treatment step, used once a week to start. To better support mature skin, this type of product also needs rich hydrating and softening ingredients.

### Can I use this pad with retinol, and in what order?

You can use this pad with retinol by applying the pad first and following with your retinol on separate nights or spaced out to keep your skin calm. This product works for mature skin, though this skin type needs extra hydrating and softening ingredients for optimal moisture.
Sources: [International Journal of Cosmetic Science, 2018](https://pubmed.ncbi.nlm.nih.gov/29574973/), [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30160014/)

### How often should I use this pad?

Start using this pad once a week in the evening, and if your skin feels fine and you see good results, you may carefully use it more often. Because this product works for mature skin but other options fit it better, it needs extra hydrating and softening ingredients to give your skin the moisture it lacks.
Sources: [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/), [International Journal of Cosmetic Science, 2018](https://pubmed.ncbi.nlm.nih.gov/29574973/)

### Can this pad clog pores, cause breakouts or purging for mature skin?

This pad is unlikely to clog pores or cause breakouts for mature skin because its safety profile is excellent and it lacks harsh or heavy pore-clogging ingredients. However, because mature skin needs rich moisture and softening ingredients to stay plump and smooth, this type of product works best when paired with a deeply nourishing cream.

### Is this pad fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (geraniol, citronellol, and linalool).

## Alternatives for mature skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/uk/p/skinceuticals/c-e-ferulic/for/mature-skin) — Superior fit — £143.35 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/uk/p/neogen-dermalogy/real-vita-c-serum/for/mature-skin) — High fit — £25.95 at Amazon
- [La Mer The Regenerating Serum](https://lovi.care/skincare/uk/p/la-mer/the-regenerating-serum/for/mature-skin) — High fit — £372.06 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/uk/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — £14.99 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/uk/p/some-by-mi/snail-truecica-miracle-repair-toner/for/mature-skin) — Superior fit — £13.98 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/uk/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/mature-skin) — Superior fit — £38.50 at Amazon

## Where to buy

- Amazon.co.uk: £15.29 (https://www.amazon.co.uk/dp/B0BPLYHDPG?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: £18.75 (https://www.lookfantastic.com/p/medicube-deep-vita-c-pad-70-pcs/17710617/)
- Notino: £19.50 (https://www.notino.co.uk/medicube/deep-vita-c-pad-intense-revitalising-pads-to-brighten-and-smooth-the-skin/p-16313458/)
Prices checked 10 Oct – 6 Nov 2026.

## Ingredients

Hippophae Rhamnoides Water, Water, Methyl Gluceth-20, Methylpropanediol, Niacinamide, Glycereth-26, Methyl Gluceth-10, Polyglycerin-3, 1,2-Hexanediol, Gluconolactone, 3-O-Ethyl Ascorbic Acid, Ethylhexylglycerin, Cymbopogon Martini Oil, Citronella Oil, Adenosine, Butylene Glycol, Disodium Edta, Spearmint Extract, Lactobacillus Lemon Peel Extract Ferment, Geraniol, Citronellol, Coptis Japonica Extract, Cucumis Melo Seed Extract, Litsea Cubeba Oil Fruit, Pelargonium Graveolens Extract, Allantoin, Dipotassium Glycyrrhizate, Panthenol, Sodium Hyaluronate, Lactic Acid, Glucose, Beta-Glucan, Linalool, Glycerin, Caprylic Capric Triglyceride, Tocopherol, Cetyl Palmitate, Ubiquinone, Polysorbate 80, Sorbitan Stearate, Sodium Benzoate, Citric Acid, Hydrogenated Lecithin, Palmitoyl Tripeptide-5, Ergothioneine, Hesperidin, Palmitoyl Tetrapeptide-10
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medicube/deep-vita-c-pad/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medicube/deep-vita-c-pad/for/mature-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/medicube/deep-vita-c-pad/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/medicube/deep-vita-c-pad/for/mature-skin
- France: https://lovi.care/skincare/fr/p/medicube/deep-vita-c-pad/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/medicube/deep-vita-c-pad/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/medicube/deep-vita-c-pad/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/medicube/deep-vita-c-pad/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/medicube/deep-vita-c-pad/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/medicube/deep-vita-c-pad/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/medicube/deep-vita-c-pad/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medicube/deep-vita-c-pad/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medicube/deep-vita-c-pad/for/mature-skin