# Medicube Deep Vita C Pad for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/uk/p/medicube/deep-vita-c-pad/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [Medicube](https://lovi.care/skincare/uk/brands/medicube)
Category: [Serums and treatments](https://lovi.care/skincare/uk/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other serums fit it better.

## Why this fit

- Offers moderate brightening and smoothing for your combination skin due to 3-O-Ethyl Ascorbic Acid and Gluconolactone, which help even skin tone and refine texture.
- Niacinamide is present for seboregulation, supporting your combination skin type, though specialized ingredients for oily shine are lacking.
- The product is safe for your combination skin, with no risks of irritation from harsh or prohibited ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/medicube/deep-vita-c-pad/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/uk/p/medicube/deep-vita-c-pad/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/uk/p/medicube/deep-vita-c-pad/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/uk/p/medicube/deep-vita-c-pad/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/uk/p/medicube/deep-vita-c-pad/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/uk/p/medicube/deep-vita-c-pad/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/uk/p/medicube/deep-vita-c-pad/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/medicube/deep-vita-c-pad/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/medicube/deep-vita-c-pad/for/oily-acne-prone-skin): High

## Key ingredients

3-O-Ethyl Ascorbic Acid, Niacinamide, Sodium Hyaluronate, Vitamin Water, Adenosine

## What the research says

- A multi-component dissolving microneedle patch loaded with glabridin, 3-O-ethyl-L-ascorbic acid, and tranexamic acid effectively reduced chloasma and age spots while demonstrating safety in clinical evaluation, alongside significant antioxidant, anti-tyrosinase, and melanin-reduction effects in vitro and in vivo. ([Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37571190/))
- Combining 10% gluconolactone chemical peeling with oxybrasion or microneedle mesotherapy increased skin hydration and decreased sebum, pH, and TEWL in twenty-one Caucasian women, with no significant differences between the two methods. ([Skin Research and Technology, 2023](https://pubmed.ncbi.nlm.nih.gov/37357656/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical adenosine treatment significantly increased the anagen hair growth rate and thick hair rate compared to placebo in Japanese women with female pattern hair loss over 12 months. ([The Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19239555/))
- Topical application of a disodium adenosine monophosphate-based formulation reduced wrinkles and hyperpigmentation while improving hydration, barrier function, skin lifting, and epidermal turnover in female participants. ([International Journal of Molecular Sciences, 2026](https://pubmed.ncbi.nlm.nih.gov/42278371/))
- Adenosine and cordycepin stimulate the Wnt/beta-catenin signaling pathway through adenosine receptor and PKA activation, promoting cell proliferation, migration, and growth factor secretion in cultured dermal fibroblasts. ([International Journal of Molecular Sciences, 2021](https://pubmed.ncbi.nlm.nih.gov/34070360/))

## Why other serums fit combination skin better

- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))

## What reviewers say

Users report that these pads effectively brighten dull complexions and fade acne scars within weeks. The pads are praised for delivering a glow and gentle exfoliation, making them suitable for most skin types, though sensitive users should be cautious. Some users note a sticky finish and potential for tingling upon application.

- Liked: Brightens & Fades Spots (mostly mentioned)
- Liked: Hydrating & Glowy (often mentioned)
- Liked: Convenient & Hygienic (sometimes noted)
- Liked: Fast Results (sometimes noted)
- Liked: Gentle Exfoliation (sometimes noted)
- Disliked: Leaky packaging (sometimes noted)
- Disliked: Sticky finish (sometimes noted)
- Disliked: Pricey (rarely noted)
- Disliked: Scent (rarely noted)
- Disliked: Tingling sensation (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does the Medicube Deep Vita C Pad work for combination skin?

This product works moderately well for combination skin, offering basic brightening and smoothing while helping to balance oil. To fit this skin type even better, a treatment of this type needs targeted ingredients like zinc PCA or propolis to manage oily shine and provide optimal hydration without leaving the skin feeling overwhelmed.
Sources: [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37571190/), [Skin Research and Technology, 2023](https://pubmed.ncbi.nlm.nih.gov/37357656/)

### Which ingredients make this pad a good fit for combination skin?

This pad fits your combination skin well thanks to 3-O-Ethyl Ascorbic Acid and gluconolactone, which help even out your skin tone and make your texture smooth. Niacinamide is also included to help balance oil levels. Treatments that fit this skin type even better need ingredients like zinc PCA and propolis to manage oily shine and provide balanced hydration.
Sources: [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37571190/)

### What does 3-O-Ethyl Ascorbic Acid do for combination skin?

3-O-Ethyl Ascorbic Acid helps brighten combination skin and fade dark spots while protecting against sun and environmental damage. This stable form of vitamin C is unlikely to cause irritation and supports an even, smooth skin tone.
Sources: [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37571190/), [Free Radical Biology & Medicine, 2025](https://pubmed.ncbi.nlm.nih.gov/39778604/)

### What does Niacinamide do for combination skin?

Niacinamide helps balance oily areas by reducing excess shine and pore size while keeping dry patches hydrated and smooth. It also works to calm redness and even out skin tone, making it very suitable for combination skin.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Where does this pad go in a skincare routine for combination skin?

This treatment pad goes in your evening routine, starting once a week and using it more often if your skin tolerates it well. To work better for combination skin, this type of product needs extra ingredients that target oily shine.

### Can I use this pad with retinol, and in what order?

You can use this pad in your evening routine, but since it contains exfoliating ingredients, use it on alternating nights with retinol to help avoid irritation. When using both on the same day, apply this treatment first after cleansing, let it absorb, and then follow with your retinol product. Combination skin of this type needs dedicated oil-controlling ingredients to manage shine alongside gentle brightening agents.

### How often should I use this pad?

Start using this pad once a week in the evening, and if your skin handles it well and you see good results, you can carefully use it more often. This product is safe for your skin, with no risks of irritation from harsh or prohibited ingredients.
Sources: [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/)

### Can this pad clog pores, cause breakouts or purging for combination skin?

This pad is unlikely to clog pores or cause breakouts for combination skin, as it has a safe profile with no harsh ingredients. However, to truly care for combination skin, a product of this type needs specialized ingredients that control oily shine alongside brightening and smoothing benefits.
Sources: [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37571190/), [Skin Research and Technology, 2023](https://pubmed.ncbi.nlm.nih.gov/37357656/)

### Is this pad fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (geraniol, citronellol, and linalool).

## Alternatives for combination skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/uk/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/combination-skin) — Superior fit — £36.96 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/uk/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin) — Superior fit — £24.20 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/uk/p/augustinus-bader/the-serum/for/combination-skin) — Superior fit — £248.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/uk/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — £14.99 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/uk/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — £30.37 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/uk/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — £14.80 at Amazon

## Where to buy

- Amazon.co.uk: £15.29 (https://www.amazon.co.uk/dp/B0BPLYHDPG?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: £18.75 (https://www.lookfantastic.com/p/medicube-deep-vita-c-pad-70-pcs/17710617/)
- Notino: £19.50 (https://www.notino.co.uk/medicube/deep-vita-c-pad-intense-revitalising-pads-to-brighten-and-smooth-the-skin/p-16313458/)
Prices checked 10 Oct – 6 Nov 2026.

## Ingredients

Hippophae Rhamnoides Water, Water, Methyl Gluceth-20, Methylpropanediol, Niacinamide, Glycereth-26, Methyl Gluceth-10, Polyglycerin-3, 1,2-Hexanediol, Gluconolactone, 3-O-Ethyl Ascorbic Acid, Ethylhexylglycerin, Cymbopogon Martini Oil, Citronella Oil, Adenosine, Butylene Glycol, Disodium Edta, Spearmint Extract, Lactobacillus Lemon Peel Extract Ferment, Geraniol, Citronellol, Coptis Japonica Extract, Cucumis Melo Seed Extract, Litsea Cubeba Oil Fruit, Pelargonium Graveolens Extract, Allantoin, Dipotassium Glycyrrhizate, Panthenol, Sodium Hyaluronate, Lactic Acid, Glucose, Beta-Glucan, Linalool, Glycerin, Caprylic Capric Triglyceride, Tocopherol, Cetyl Palmitate, Ubiquinone, Polysorbate 80, Sorbitan Stearate, Sodium Benzoate, Citric Acid, Hydrogenated Lecithin, Palmitoyl Tripeptide-5, Ergothioneine, Hesperidin, Palmitoyl Tetrapeptide-10
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medicube/deep-vita-c-pad/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medicube/deep-vita-c-pad/for/combination-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/medicube/deep-vita-c-pad/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/medicube/deep-vita-c-pad/for/combination-skin
- France: https://lovi.care/skincare/fr/p/medicube/deep-vita-c-pad/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/medicube/deep-vita-c-pad/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/medicube/deep-vita-c-pad/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/medicube/deep-vita-c-pad/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/medicube/deep-vita-c-pad/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/medicube/deep-vita-c-pad/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/medicube/deep-vita-c-pad/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medicube/deep-vita-c-pad/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medicube/deep-vita-c-pad/for/combination-skin