# Medicube Deep Peptide Radiance Mask for oily acne-prone skin

**Lovi Fit: Superior fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/uk/p/medicube/deep-peptide-radiance-mask/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [Medicube](https://lovi.care/skincare/uk/brands/medicube)
Category: [Face masks](https://lovi.care/skincare/uk/best/face-masks)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best nourishing masks for oily acne-prone skin.

## Why this fit

- Excellent for your oily skin, this mask features niacinamide and Centella Asiatica Leaf Extract to help regulate oil production and reduce inflammation, addressing your concerns with acne and breakouts.
- The high concentration of peptides like Acetyl Hexapeptide-1 and Palmitoyl Tripeptide-5 further enhances skin elasticity and provides plumping benefits, complementing the barrier-supporting ingredients.
- The formula is safe for your skin, with no harsh ingredients and the inclusion of soothing agents like Panthenol and Allantoin.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/medicube/deep-peptide-radiance-mask/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/uk/p/medicube/deep-peptide-radiance-mask/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/uk/p/medicube/deep-peptide-radiance-mask/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/uk/p/medicube/deep-peptide-radiance-mask/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/uk/p/medicube/deep-peptide-radiance-mask/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/uk/p/medicube/deep-peptide-radiance-mask/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/uk/p/medicube/deep-peptide-radiance-mask/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/medicube/deep-peptide-radiance-mask/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/medicube/deep-peptide-radiance-mask/for/oily-acne-prone-skin): Superior (this page)

## Key ingredients

Peptide Complex, Niacinamide, Centella Asiatica Leaf Extract, Hydrolyzed Hyaluronic Acid, Ceramide Np

## What the research says

- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Supramolecular collagen nanoparticles composed of lactoferrin, recombinant human collagen, and palmitoyl tripeptide-5 improved transdermal efficiency by 69.90% and demonstrated moisturizing, whitening, wrinkle reduction, and firming effects. ([Colloids and Surfaces. B, Biointerfaces, 2025](https://pubmed.ncbi.nlm.nih.gov/39383579/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## What reviewers say

Based on limited data, users love this mask for its intense hydration and ability to provide an instant glow, making it ideal for dry, dull, or sensitive skin. The peptide-rich essence is praised for plumping fine lines and soothing irritation without a sticky feel. Some users find the price high for frequent use and note the sheet size can be slightly small.

- Liked: Intense hydration (mostly mentioned)
- Liked: Instant radiance (often mentioned)
- Liked: Non-sticky finish (sometimes noted)
- Liked: Soothing and plumping (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Handling difficulty (rarely noted)
- Disliked: Sheet fit issues (rarely noted)

## How to apply

- Use your sheet mask PM routine about 1-3 times a week to help with breakouts. Start slowly to see how your oily skin feels before using it more often.
- Put on your sheet mask after cleansing and toning, but before applying your final moisturizer. This helps your skin absorb all the good ingredients easily.
- Unfold the sheet mask and smooth it gently over your face without rubbing. Leave it on for ten to fifteen minutes ⏱ and gently pat any leftover essence into your skin.
- Apply the sheet mask directly onto clean and dry skin for the best results against blemishes. There is no need to wash your face again after removing the mask.
- Avoid getting the product into your eyes and always do a quick patch test before your very first use.
- Video: https://storage.pora.ai/cf9cbc1593b43309df7ca9cfe4fbbdae.mp4

## Questions and answers

### What makes medicube Deep Peptide Radiance Mask one of the best fits for oily acne-prone skin?

This mask is one of the best fits because it features niacinamide and Centella Asiatica Leaf Extract to help calm breakouts and keep oil in check, while soothing ingredients like panthenol maintain a safe, gentle touch. Its peptide complex further helps firm and smooth the skin without clogging pores.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/)

### Which ingredients make this mask a good fit for oily acne-prone skin?

This mask is a great fit for your oily acne-prone skin because niacinamide and Centella Asiatica Leaf Extract help control extra oil and calm breakouts. It also features soothing panthenol and allantoin to keep your skin safe and comfortable without clogging pores.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/)

### What does Peptide Complex do for oily acne-prone skin?

Peptide Complex helps oily acne-prone skin by improving skin barrier function and reducing acne symptoms and breakouts. It may also help decrease closed bumps and surface oils.
Sources: [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/32697858/)

### What does Niacinamide do for oily acne-prone skin?

Niacinamide helps balance oil production, calms redness, and is unlikely to irritate oily, acne-prone skin while improving blemishes. Clinical tests show it reduces excess oil and helps clear up both inflammatory and non-inflammatory acne breakouts.
Sources: [Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38299457/)

### Where does this mask go in a skincare routine for oily acne-prone skin?

This mask fits best in your weekly routine after cleansing and before toning. It helps balance oil production and soothe breakouts safely while enhancing firmness.
Sources: [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/)

### Can I use this mask with retinol, and in what order?

You can use this mask with retinol, applying the mask after your retinol treatment to help soothe your skin and keep it calm. This formula is safe and unlikely to cause irritation because it includes soothing ingredients like panthenol and allantoin that support your skin barrier.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### How often should I use this mask?

This nourishing mask is an excellent fit for your oily acne-prone skin, featuring niacinamide and Centella Asiatica Leaf Extract to help control oil and soothe breakouts. It has a safe and gentle formula, making it comfortable for regular use as part of your routine.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### Can this mask clog pores, cause breakouts or purging for oily acne-prone skin?

This mask is unlikely to clog pores or cause breakouts for oily acne-prone skin because it features niacinamide and Centella Asiatica Leaf Extract to help calm redness and manage oil production. Soothing ingredients like panthenol and allantoin further support a safe, comfortable experience without harsh elements.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/)

### Is this mask fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Behenyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for oily acne-prone skin

- [Anua Heartleaf 77% Soothing Sheet Mask](https://lovi.care/skincare/uk/p/anua/heartleaf-77-soothing-sheet-mask/for/oily-acne-prone-skin) — Superior fit — £21.00 at Amazon
- [Mediheal Watermide Essential Mask](https://lovi.care/skincare/uk/p/mediheal/watermide-essential-mask/for/oily-acne-prone-skin) — High fit — £17.00 at Amazon
- [Pyunkang Yul Ceramide Calming Mask Pack](https://lovi.care/skincare/uk/p/pyunkang-yul/ceramide-calming-mask-pack/for/oily-acne-prone-skin) — High fit — £18.97 at Amazon

## Pairs well with

- Cleanser: [Paula's Choice CLEAR Pore Normalizing Cleanser](https://lovi.care/skincare/uk/p/paula-s-choice/clear-pore-normalizing-cleanser/for/oily-acne-prone-skin) — Superior fit — £26.00 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/uk/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — £30.37 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/uk/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-acne-prone-skin) — Superior fit — £14.80 at Amazon

## Where to buy

- Amazon.co.uk: £17.00 (https://www.amazon.co.uk/dp/B0HGBQSTDY?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- Notino: £4.10 (https://www.notino.co.uk/medicube/deep-peptide-radiance-mask-moisturising-face-sheet-mask-for-increased-skin-elasticity/p-16364197/)
Prices checked 10 Oct – 31 Oct 2026.

## Ingredients

Water, Dipropylene Glycol, Glycerin, Butylene Glycol, Niacinamide, 1,2-Hexanediol, Cetyl Ethylhexanoate, Panthenol, Allantoin, Xylitol, Centella Asiatica Leaf Extract, Lactobacillus Lysate Ferment, Lactococcus Lysate Ferment, Bifida Lysate Ferment, Caprylyl Glycol, Sorbitan Laurate, Hydrogenated Lecithin, Hydrolyzed Hyaluronic Acid, Tocopherol, Asiaticoside, Madecassic Acid, Asiatic Acid, Acetyl Dipeptide-1, Cetyl Ester, Acetyl Hexapeptide-1, Palmitoyl Tripeptide-5, Beta-Glucan, Ceramide Np, Acetyl Octapeptide-3, Hydrogenated Oil, Behenyl Alcohol, Polyglyceryl-3 Methylglucose Distearate, Arginine, Carbomer, Adenosine, Hydroxyethylcellulose, Ethylhexylglycerin, Disodium Edta
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medicube/deep-peptide-radiance-mask/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medicube/deep-peptide-radiance-mask/for/oily-acne-prone-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/medicube/deep-peptide-radiance-mask/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/medicube/deep-peptide-radiance-mask/for/oily-acne-prone-skin
- France: https://lovi.care/skincare/fr/p/medicube/deep-peptide-radiance-mask/for/oily-acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/medicube/deep-peptide-radiance-mask/for/oily-acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/medicube/deep-peptide-radiance-mask/for/oily-acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/medicube/deep-peptide-radiance-mask/for/oily-acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/medicube/deep-peptide-radiance-mask/for/oily-acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/medicube/deep-peptide-radiance-mask/for/oily-acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/medicube/deep-peptide-radiance-mask/for/oily-acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medicube/deep-peptide-radiance-mask/for/oily-acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medicube/deep-peptide-radiance-mask/for/oily-acne-prone-skin