# Mederma PM Intensive Overnight Scar Cream for dry skin

**Lovi Fit: Average fit for dry skin.**
Dry Skin Fit: Average · Effectiveness: Average · Safety: Low Risk.

Page: https://lovi.care/skincare/uk/p/mederma/pm-intensive-overnight-scar-cream/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [Mederma](https://lovi.care/skincare/uk/brands/mederma)
Category: [Serums and treatments](https://lovi.care/skincare/uk/best/serums)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry skin; other serums fit it better.

## Why this fit

- Offers excellent scar treatment for your dry skin due to the presence of Onion Bulb Extract and Copper Tripeptide-1, which improve skin texture and reduce the appearance of scars.
- Glycerin and Panthenol provide hydration, but the formula lacks sufficient emollient and occlusive ingredients for optimal results on dry or flaky skin.
- The product is generally safe for your dry skin, though the presence of alcohol carries a slight risk of irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/mederma/pm-intensive-overnight-scar-cream/for/oily-skin): Low
- [Dry skin](https://lovi.care/skincare/uk/p/mederma/pm-intensive-overnight-scar-cream/for/dry-skin): Average (this page)
- [Combination skin](https://lovi.care/skincare/uk/p/mederma/pm-intensive-overnight-scar-cream/for/combination-skin): Low
- [Sensitive skin](https://lovi.care/skincare/uk/p/mederma/pm-intensive-overnight-scar-cream/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/uk/p/mederma/pm-intensive-overnight-scar-cream/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/uk/p/mederma/pm-intensive-overnight-scar-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/uk/p/mederma/pm-intensive-overnight-scar-cream/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/mederma/pm-intensive-overnight-scar-cream/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/mederma/pm-intensive-overnight-scar-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Dimethicone, Onion Bulb Extract, Copper Tripeptide-1, Aloe Barbadensis Leaf, Hydrolyzed Collagen

## What the research says

- Topical 12% onion extract gel applied early on Pfannenstiel's cesarean section scars in Asians improved scar height and scar symptoms compared to placebo, with no significant difference in scar redness, pliability, or overall appearance. ([Dermatology Research and Practice, 2012](https://pubmed.ncbi.nlm.nih.gov/22924037/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate can be used safely in cosmetic formulations at concentrations up to 5%, and Benzyl Alcohol is safe up to 10% in hair dyes, despite causing nonimmunologic contact reactions. ([International Journal of Toxicology, 2001](https://pubmed.ncbi.nlm.nih.gov/11766131/))
- Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups. ([Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/))
- A dimethicone skin protectant lotion significantly decreased visual scoring and transepidermal water loss compared to vehicle control and SLS-only treated sites in 12 healthy humans exposed to sodium lauryl sulfate. ([Skin Research and Technology, 2000](https://pubmed.ncbi.nlm.nih.gov/11428946/))
- Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms. ([Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/))
- Topical onion extract improved scar colour compared to silicon gel, while silicon gel was superior in decreasing scar height in 60 patients with hypertrophic and keloid scars, with the most effective results obtained from combining onion extract and silicon gel. ([Journal of Wound Care, 2007](https://pubmed.ncbi.nlm.nih.gov/17722521/))
- Silicone derivative plus onion extract gel reduced pain, itching, and pigmentation compared to placebo in patients after median sternotomy. ([International Wound Journal, 2012](https://pubmed.ncbi.nlm.nih.gov/22168750/))
- Onion extract gel significantly improved scar softness, redness, texture, and global appearance compared to no treatment in 60 subjects with postsurgical scars on the upper chest over 10 weeks. ([Journal of Cosmetic Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18482012/))
- Topical copper tripeptide complex on CO2 laser-resurfaced skin caused no significant reduction in erythema or objective improvement in wrinkles compared to controls, but significantly increased patient satisfaction regarding overall skin quality. ([Archives of Facial Plastic Surgery, 2006](https://pubmed.ncbi.nlm.nih.gov/16847171/))
- A novel regimen combining a hydroxy acid-based scrub and copper tripeptide serum significantly reduced adherent scalp flaking by 61.24%, increased hair density by 12.48%, increased hair thickness by 25.36%, and improved scalp skin hydration by 76.24% in adults with mild to moderate dandruff over 15 days. ([Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/39449909/))
- The combination of Thermus thermophilus and Bacillus subtilis mixed-culture ferment extract and copper tripeptide-1 GHK-Cu reduced inflammatory cytokines, protected skin explants from UV-induced damage, and improved wrinkles and skin barrier conditions compared to individual components or controls. ([Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief. ([Plastic and Reconstructive Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29649056/))
- Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo. ([Journal of Alternative and Complementary Medicine, 2010](https://pubmed.ncbi.nlm.nih.gov/20569031/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))

## Why other serums fit dry skin better

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Daily application of Galactomyces ferment filtrate-containing skin products for 12 months significantly and cumulatively reversed 11-year facial skin aging parameters of wrinkles, hyperpigmented spots, and roughness, and increased skin hydration in 86 female volunteers. ([Journal of Clinical Medicine, 2023](https://pubmed.ncbi.nlm.nih.gov/36769815/))

## What reviewers say

Based on a very large amount of data, users report this cream is effective at softening and flattening scars from surgery, acne, and injuries with consistent use over months. Many appreciate the convenient, non-greasy application. However, results can take a long time to become noticeable, and a significant number of users find the scent unpleasant.

- Liked: Effective on scars (often mentioned)
- Disliked: Slow results (often mentioned)
- Disliked: Unpleasant smell (often mentioned)
- Liked: Convenient application (sometimes noted)
- Liked: Good absorption (sometimes noted)
- Liked: Improves texture (sometimes noted)
- Disliked: Price vs quantity (sometimes noted)
- Disliked: Skin reactions (rarely noted)

## How to apply

- Apply this serum PM, starting 3×/week and working up to daily use as your skin adjusts.
- Place the serum after cleansing and toner, but right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on slightly damp skin to help lock in extra moisture.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Mederma PM Intensive Overnight Scar Cream work for dry skin?

This cream works decently to improve scars on dry skin, but it lacks enough rich moisturizing oils and sealants to keep dry skin fully soft and hydrated. A product of this type needs richer emollients and occlusives to lock in moisture and soothe flaky areas.
Sources: [Dermatology Research and Practice, 2012](https://pubmed.ncbi.nlm.nih.gov/22924037/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Which ingredients make this cream a good fit for dry skin?

This cream works for your dry skin thanks to glycerin and panthenol, which provide hydration. To truly thrive, dry skin needs a richer blend of softening and sealing ingredients to lock in moisture and prevent flakiness.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### What does Dimethicone do for dry skin?

Dimethicone helps protect dry skin and keeps it smooth by forming a gentle, breathable layer on top. It is unlikely to lock in moisture on its own as well as heavy protectants like petrolatum, so dry skin often needs formulas that combine dimethicone with hydrating ingredients like glycerin.
Sources: [Ostomy/wound Management, 2005](https://pubmed.ncbi.nlm.nih.gov/16439809/), [Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/)

### What does Onion Bulb Extract do for dry skin?

Onion Bulb Extract is not typically used for dry skin, as its main benefits are for scars, redness, and blemishes. A product for dry skin needs nourishing oils, shea butter, or glycerin to restore moisture and leave the skin soft and smooth.

### Where does this cream go in a skincare routine for dry skin?

This cream goes in the evening routine after cleansing and before moisturizing. Because dry skin needs extra richness, this type of product works best when paired with rich softening ingredients and heavy moisturizing creams that seal in hydration.

### Can I use this cream with retinol, and in what order?

You can use this cream in your evening routine after cleansing and before your moisturizer, but you should apply it on alternate nights from your retinol to help prevent irritation. Because this formula contains alcohol, using it at the same time as retinol may increase your chances of dry or flaky skin.

### How often should I use this cream?

You can use this treatment cream in the evening as part of your routine. This product works for dry skin, though it needs extra rich, softening ingredients and skin-protecting sealants to keep dry or flaky skin feeling fully smooth and comfortable.
Sources: [Dermatology Research and Practice, 2012](https://pubmed.ncbi.nlm.nih.gov/22924037/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Can this cream clog pores, cause breakouts or purging for dry skin?

This cream is unlikely to clog pores or cause breakouts on dry skin, though the presence of alcohol carries a slight risk of irritation. A product for this skin needs richer softeners and sealants to lock in moisture and prevent flaking.

### Is this cream fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (alcohol and isopropyl alcohol).

## Alternatives for dry skin

- [SKIN1004 Madagascar Centella Spot Cream](https://lovi.care/skincare/uk/p/skin1004/madagascar-centella-spot-cream/for/dry-skin) — High fit — £16.02 at Amazon
- [SKIN1004 Madagascar Centella Asiatica Ampoule](https://lovi.care/skincare/uk/p/skin1004/madagascar-centella-asiatica-ampoule/for/dry-skin) — High fit — £14.00 at Amazon
- [Purito Galacto Niacin 97 Power Essence](https://lovi.care/skincare/uk/p/purito/galacto-niacin-97-power-essence/for/dry-skin) — High fit — £16.80 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/uk/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — £8.29 at Amazon
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/uk/p/dear-klairs/supple-preparation-unscented-toner/for/dry-skin) — Superior fit — £11.49 at Amazon
- Moisturizer: [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/uk/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/dry-skin) — Superior fit — £14.74 at Amazon

## Where to buy

No store in United Kingdom has a checked price for this product, so the page shows none.

## Ingredients

Water, Cetearyl Alcohol, Glycerin, C12-15 Alkyl Benzoate, Dicaprylyl Carbonate, Pentylene Glycol, Cyclomethicone, Arachidyl Alcohol, Alcohol, Behenyl Alcohol, Arachidyl Glucoside, Onion Bulb Extract, Copper Tripeptide-1, Aloe Barbadensis Leaf, Cetearyl Glucoside, Tocopheryl Acetate, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Hydroxyethylcellulose, Hydrolyzed Soy Protein, Glycine, Panthenol, Hydrolyzed Collagen, Peg-400, Arginine Hcl, Leucine, Lysine Hydrochloride, Alanine, Sodium Lactate, Aspartic Acid, Glucose, Glutamic Acid, Isopropyl Alcohol, Mannitol, Sorbitol, Tromethamine, Valine, Histidine Hydrochloride, Isoleucine, Phenylalanine, Tyrosine, Potassium Sorbate, Sodium Benzoate, Citric Acid, Sodium Hydroxide
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/mederma/pm-intensive-overnight-scar-cream/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/mederma/pm-intensive-overnight-scar-cream/for/dry-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/mederma/pm-intensive-overnight-scar-cream/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/mederma/pm-intensive-overnight-scar-cream/for/dry-skin
- France: https://lovi.care/skincare/fr/p/mederma/pm-intensive-overnight-scar-cream/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/mederma/pm-intensive-overnight-scar-cream/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/mederma/pm-intensive-overnight-scar-cream/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/mederma/pm-intensive-overnight-scar-cream/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/mederma/pm-intensive-overnight-scar-cream/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/mederma/pm-intensive-overnight-scar-cream/for/dry-skin
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- Saudi Arabia: https://lovi.care/skincare/sa/p/mederma/pm-intensive-overnight-scar-cream/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/mederma/pm-intensive-overnight-scar-cream/for/dry-skin