# Mederma PM Intensive Overnight Scar Cream for dry sensitive skin

**Lovi Fit: Average fit for dry sensitive skin.**
Dry Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/uk/p/mederma/pm-intensive-overnight-scar-cream/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [Mederma](https://lovi.care/skincare/uk/brands/mederma)
Category: [Serums and treatments](https://lovi.care/skincare/uk/best/serums)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry sensitive skin; other serums fit it better.

## Why this fit

- Offers moderate suitability for your dry and sensitive skin as glycerin and panthenol provide humectant action to support hydration and reduce flakiness. Onion bulb extract and copper tripeptide-1 are present to improve skin texture and reduce the appearance of scars.
- The formula offers general skincare benefits and hydration, which are supportive for your dry or flaky skin and sensitivity.
- The safety profile is excellent, with no risks of irritation for your dry and sensitive skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/mederma/pm-intensive-overnight-scar-cream/for/oily-skin): Low
- [Dry skin](https://lovi.care/skincare/uk/p/mederma/pm-intensive-overnight-scar-cream/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/uk/p/mederma/pm-intensive-overnight-scar-cream/for/combination-skin): Low
- [Sensitive skin](https://lovi.care/skincare/uk/p/mederma/pm-intensive-overnight-scar-cream/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/uk/p/mederma/pm-intensive-overnight-scar-cream/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/uk/p/mederma/pm-intensive-overnight-scar-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/uk/p/mederma/pm-intensive-overnight-scar-cream/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/mederma/pm-intensive-overnight-scar-cream/for/dry-sensitive-skin): Average (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/mederma/pm-intensive-overnight-scar-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Dimethicone, Onion Bulb Extract, Copper Tripeptide-1, Aloe Barbadensis Leaf, Hydrolyzed Collagen

## What the research says

- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups. ([Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/))
- A dimethicone skin protectant lotion significantly decreased visual scoring and transepidermal water loss compared to vehicle control and SLS-only treated sites in 12 healthy humans exposed to sodium lauryl sulfate. ([Skin Research and Technology, 2000](https://pubmed.ncbi.nlm.nih.gov/11428946/))
- Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms. ([Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/))
- Topical onion extract improved scar colour compared to silicon gel, while silicon gel was superior in decreasing scar height in 60 patients with hypertrophic and keloid scars, with the most effective results obtained from combining onion extract and silicon gel. ([Journal of Wound Care, 2007](https://pubmed.ncbi.nlm.nih.gov/17722521/))
- Silicone derivative plus onion extract gel reduced pain, itching, and pigmentation compared to placebo in patients after median sternotomy. ([International Wound Journal, 2012](https://pubmed.ncbi.nlm.nih.gov/22168750/))
- Topical 12% onion extract gel applied early on Pfannenstiel's cesarean section scars in Asians improved scar height and scar symptoms compared to placebo, with no significant difference in scar redness, pliability, or overall appearance. ([Dermatology Research and Practice, 2012](https://pubmed.ncbi.nlm.nih.gov/22924037/))
- Topical copper tripeptide complex on CO2 laser-resurfaced skin caused no significant reduction in erythema or objective improvement in wrinkles compared to controls, but significantly increased patient satisfaction regarding overall skin quality. ([Archives of Facial Plastic Surgery, 2006](https://pubmed.ncbi.nlm.nih.gov/16847171/))
- A novel regimen combining a hydroxy acid-based scrub and copper tripeptide serum significantly reduced adherent scalp flaking by 61.24%, increased hair density by 12.48%, increased hair thickness by 25.36%, and improved scalp skin hydration by 76.24% in adults with mild to moderate dandruff over 15 days. ([Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/39449909/))
- The combination of Thermus thermophilus and Bacillus subtilis mixed-culture ferment extract and copper tripeptide-1 GHK-Cu reduced inflammatory cytokines, protected skin explants from UV-induced damage, and improved wrinkles and skin barrier conditions compared to individual components or controls. ([Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief. ([Plastic and Reconstructive Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29649056/))
- Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo. ([Journal of Alternative and Complementary Medicine, 2010](https://pubmed.ncbi.nlm.nih.gov/20569031/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))

## What reviewers say

Based on a very large amount of data, users report this cream is effective at softening and flattening scars from surgery, acne, and injuries with consistent use over months. Many appreciate the convenient, non-greasy application. However, results can take a long time to become noticeable, and a significant number of users find the scent unpleasant.

- Liked: Effective on scars (often mentioned)
- Disliked: Slow results (often mentioned)
- Disliked: Unpleasant smell (often mentioned)
- Liked: Convenient application (sometimes noted)
- Liked: Good absorption (sometimes noted)
- Liked: Improves texture (sometimes noted)
- Disliked: Price vs quantity (sometimes noted)
- Disliked: Skin reactions (rarely noted)

## How to apply

- Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
- Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
- Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
- Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
- Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Mederma PM Intensive Overnight Scar Cream work for dry sensitive skin?

Mederma PM Intensive Overnight Scar Cream works moderately well for dry and sensitive skin because glycerin and panthenol help boost hydration and reduce flakiness. It is unlikely to cause irritation due to its gentle formula, though dry skin of this type needs richer moisture-locking ingredients and skin-softening oils for the best results.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Which ingredients make this cream a good fit for dry sensitive skin?

Glycerin and panthenol make this cream a good fit by adding moisture and reducing flakiness on dry skin. However, to truly care for dry sensitive skin, this type of product needs a richer blend of softening and sealing ingredients to lock in hydration.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Dimethicone do for dry sensitive skin?

Dimethicone helps protect dry sensitive skin, though it may show varying performance compared to other protectants. This type of product needs gentle, hydrating ingredients that support the skin barrier without causing irritation.
Sources: [Ostomy/wound Management, 2005](https://pubmed.ncbi.nlm.nih.gov/16439809/)

### What does Onion Bulb Extract do for dry sensitive skin?

Onion bulb extract may help calm redness and soothe irritation, but it is an average fit for dry sensitive skin because it lacks rich moisturizing ingredients. A product of this type needs soothing plant extracts and heavy, gentle moisturizers to deeply soften dry skin and keep sensitive skin comfortable.
Sources: [Pharmaceuticals, 2023](https://pubmed.ncbi.nlm.nih.gov/37895850/), [Medicine, 2026](https://pubmed.ncbi.nlm.nih.gov/41790658/)

### Where does this cream go in a skincare routine for dry sensitive skin?

This treatment goes in the evening routine after your toner and before your moisturizer. Dry sensitive skin works best with products that provide gentle hydration and soothe flakiness.

### Can I use this cream with retinol, and in what order?

You can use this cream alongside retinol by applying your retinol first at night, letting it absorb, and then following with this treatment cream. This product is unlikely to cause irritation on dry and sensitive skin, but drier skin types often do better with rich creams that pack extra barrier-restoring oils and soothing ceramides.

### How often should I use this cream?

Apply this treatment in the evening as part of your nighttime routine, or during weekly routine steps. This helps your dry and sensitive skin stay hydrated and smooth while being very unlikely to cause irritation.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Can this cream clog pores, cause breakouts or purging for dry sensitive skin?

This cream is unlikely to clog pores or cause breakouts for dry and sensitive skin, as its safety profile is excellent and it lacks harsh ingredients that typically trigger irritation. It provides helpful moisture, but a product for this skin works best when it also includes richer soothing oils and barrier-repairing ingredients to fully protect dry patches.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Is this cream fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (alcohol and isopropyl alcohol).

## Alternatives for dry sensitive skin

- [SKIN1004 Madagascar Centella Spot Cream](https://lovi.care/skincare/uk/p/skin1004/madagascar-centella-spot-cream/for/dry-sensitive-skin) — High fit — £16.02 at Amazon
- [Clarins Double Serum](https://lovi.care/skincare/uk/p/clarins/double-serum/for/dry-sensitive-skin) — High fit — £52.00 at Amazon
- [Purito Galacto Niacin 97 Power Essence](https://lovi.care/skincare/uk/p/purito/galacto-niacin-97-power-essence/for/dry-sensitive-skin) — Average fit — £16.80 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/uk/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — £8.29 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/uk/p/clarins/soothing-toning-lotion/for/dry-sensitive-skin) — Superior fit — £17.91 at Amazon
- Moisturizer with Sun Protection: [Real Barrier Mild Sun Cream](https://lovi.care/skincare/uk/p/real-barrier/mild-sun-cream/for/dry-sensitive-skin) — Superior fit — £19.01 at Amazon

## Where to buy

No store in United Kingdom has a checked price for this product, so the page shows none.

## Ingredients

Water, Cetearyl Alcohol, Glycerin, C12-15 Alkyl Benzoate, Dicaprylyl Carbonate, Pentylene Glycol, Cyclomethicone, Arachidyl Alcohol, Alcohol, Behenyl Alcohol, Arachidyl Glucoside, Onion Bulb Extract, Copper Tripeptide-1, Aloe Barbadensis Leaf, Cetearyl Glucoside, Tocopheryl Acetate, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Hydroxyethylcellulose, Hydrolyzed Soy Protein, Glycine, Panthenol, Hydrolyzed Collagen, Peg-400, Arginine Hcl, Leucine, Lysine Hydrochloride, Alanine, Sodium Lactate, Aspartic Acid, Glucose, Glutamic Acid, Isopropyl Alcohol, Mannitol, Sorbitol, Tromethamine, Valine, Histidine Hydrochloride, Isoleucine, Phenylalanine, Tyrosine, Potassium Sorbate, Sodium Benzoate, Citric Acid, Sodium Hydroxide
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/mederma/pm-intensive-overnight-scar-cream/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/mederma/pm-intensive-overnight-scar-cream/for/dry-sensitive-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/mederma/pm-intensive-overnight-scar-cream/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/mederma/pm-intensive-overnight-scar-cream/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/mederma/pm-intensive-overnight-scar-cream/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/mederma/pm-intensive-overnight-scar-cream/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/mederma/pm-intensive-overnight-scar-cream/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/mederma/pm-intensive-overnight-scar-cream/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/mederma/pm-intensive-overnight-scar-cream/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/mederma/pm-intensive-overnight-scar-cream/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/mederma/pm-intensive-overnight-scar-cream/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/mederma/pm-intensive-overnight-scar-cream/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/mederma/pm-intensive-overnight-scar-cream/for/dry-sensitive-skin