Mederma Advanced Scar Gel for mature skin
Allantoin
Onion Extract
Sodium Hyaluronate
Panthenol
Peg-200High
- HighNormal Skin Fit
- AverageEffectiveness
- HighSafety
A great choice for mature skin; a few serums fit it even better.
This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate scar treatment for your normal skin, as onion bulb extract and allantoin work to smooth texture and reduce redness, though these ingredients do not directly address your primary concern of wrinkles and fine lines.
- Panthenol and sodium hyaluronate provide beneficial hydration and barrier support, which are excellent for normal skin.
- The product is safe for your normal skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.
How to apply
- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
People Say
★4.3Overall rating based on 2.7k+ reviewsBased on a very large amount of data, users consistently report that this gel effectively softens, flattens, and fades the discoloration of various scar types, including acne pockmarks, surgical incisions, and burns. While results are widely praised, they are heavily dependent on long-term consistency, with visible improvements typically requiring 4 to 8 weeks for new scars and several months for older ones.
Highlights
Effective scar fading Often Mentioned
- “significantly lightens dark spots”
- “reduces redness”
- “fades acne marks”
Improves skin texture Often Mentioned
- “flattens raised scars”
- “softens keloids”
- “smooths rough skin”
Slow results Often Mentioned
- “requires patience”
- “takes months”
- “no instant fix”
- “slow progress”
Easy application Sometimes Noted
- “absorbs quickly”
- “non-greasy”
- “lightweight gel”
- “once-daily use”
Versatile treatment Sometimes Noted
- “works on surgical scars”
- “burn marks”
- “old injuries”
- “stretch marks”
Flaking or peeling Sometimes Noted
- “leaves residue”
- “peels off”
- “clumps under makeup”
- “white film”
Minor irritation Rarely Noted
- “causes itching”
- “stinging sensation”
- “mild redness”
- “tingling”
Unpleasant scent Rarely Noted
- “onion-like smell”
- “strong odor”
- “medicinal scent”
Sources: lovi.care, walmart.com, walgreens.com, target.com, iherb.com, influenster.com, and more
Questions and answers
What makes Mederma Advanced Scar Gel a great fit for mature skin?
Mederma Advanced Scar Gel is a great fit because panthenol and sodium hyaluronate provide beneficial hydration and barrier support. Additionally, onion bulb extract and allantoin work to smooth texture and reduce redness.
American Journal of Clinical Dermatology, 2002The Journal of Dermatological Treatment, 2017
Which ingredients make this gel a good fit for mature skin?
Panthenol and sodium hyaluronate make this gel a good fit for mature skin by providing deep hydration and supporting the skin barrier. Allantoin and onion extract also help to smooth texture and reduce redness.
American Journal of Clinical Dermatology, 2002The Journal of Dermatological Treatment, 2017
What does Allantoin do for mature skin?
Allantoin helps soothe dry and irritated mature skin while supporting a smooth and healthy skin barrier. This ingredient may improve overall skin softness and comfort, making it a helpful addition to daily anti-aging routines.
What does Onion Extract do for mature skin?
Onion extract helps mature skin by providing powerful antioxidants that fight oxidative stress and inflammation while supporting a smooth, even look. It may also help prevent excess scarring and maintain firmness by balancing collagen production and cell growth. A product for this skin type needs nourishing ingredients and antioxidants to protect against aging and keep the skin soft.
Naunyn-Schmiedeberg's Archives of Pharmacology, 2025International Journal of Molecular Medicine, 2010
Where does this gel go in a skincare routine for mature skin?
This treatment goes in the evening routine after cleansing and before moisturizing, which keeps usage simple and avoids sun exposure concerns. It is safe for this skin, providing hydration and barrier support with a low risk of irritation.
Can I use this gel with retinol, and in what order?
You can use this gel in your routine, applying your treatment step at night after cleansing and toning, and following with your moisturizer. Panthenol and sodium hyaluronate in the formula provide helpful hydration and barrier support that is unlikely to cause irritation.
American Journal of Clinical Dermatology, 2002The Journal of Dermatological Treatment, 2017
How often should I use this gel?
You can use this gel in your evening routine, as treatments fit best at night for simplicity and extra safety around sun exposure. It is safe for your skin with no risk of irritation, helping to smooth texture and reduce redness.
American Journal of Clinical Dermatology, 2002The Journal of Dermatological Treatment, 2017
Can this gel clog pores, cause breakouts or purging for mature skin?
This gel is unlikely to clog pores or cause breakouts for mature skin because it lacks harsh or heavy ingredients that typically trigger irritation or block pores. It is generally safe for your skin type, though it focuses more on smoothing scars than on targeting wrinkles and fine lines.
Is this gel fragrance-free and alcohol-free?
It has no fragrance and contains drying alcohol (alcohol).
What the research says
Topical onion extract improved scar colour compared to silicon gel, while silicon gel was superior in decreasing scar height in 60 patients with hypertrophic and keloid scars, with the most effective results obtained from combining onion extract and silicon gel.
Journal of Wound Care, 2007Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment.
American Journal of Clinical Dermatology, 2002A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability.
The Journal of Dermatological Treatment, 2017A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment.
Journal of Cosmetic Dermatology, 2025Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel.
Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo.
Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment.
Aesthetic Plastic Surgery, 2018Silicone derivative plus onion extract gel reduced pain, itching, and pigmentation compared to placebo in patients after median sternotomy.
International Wound Journal, 2012Topical 12% onion extract gel applied early on Pfannenstiel's cesarean section scars in Asians improved scar height and scar symptoms compared to placebo, with no significant difference in scar redness, pliability, or overall appearance.
Dermatology Research and Practice, 2012Onion extract gel significantly improved scar softness, redness, texture, and global appearance compared to no treatment in 60 subjects with postsurgical scars on the upper chest over 10 weeks.
Journal of Cosmetic Dermatology, 2008Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.
Journal of Cosmetic Dermatology, 2019Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans.
Arzneimittel-Forschung, 2000Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two.
Auris, Nasus, Larynx, 2020Topical excipients like propylene glycol, polyethylene glycol 200, and octisalate alter the stratum corneum recovery, lateral diffusion, and in vitro flux of ibuprofen in humans.
Journal of Pharmaceutical Sciences, 2014
Ingredients
Water, Peg-200, Alcohol, Xanthan Gum, Onion Bulb Extract, Lecithin, Methylparaben, Sorbic Acid, Panthenol, Sodium Hyaluronate, Allantoin
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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