Mary Kay Timewise Pore Minimizer for acne-prone skin

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Questions and answers

What the research says

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

  Journal of Cosmetic Dermatology, 2020

• Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

  International Journal of Cosmetic Science, 2001

• A biomimetic mixture of Evodia rutaecarpa extract components significantly inhibited UVB-induced PGE2 release in cultured keratinocytes and reduced methyl nicotinate-induced erythema in human skin compared to bisabolol.

  Journal of Dermatological Science, 2006

• Rutaecarpine significantly suppressed ultraviolet A-induced expression, protein levels, and gelatinolytic activities of MMP-2 and MMP-9 while decreasing reactive oxygen species generation in HaCaT human keratinocytes compared to irradiated cells without rutaecarpine.

  European Journal of Pharmacology, 2004

• The purity of evodiamine and rutaecarpine does not significantly affect their transdermal permeation through porcine skin, but lipophilic enhancers promote their transdermal rate while topical cream produces a dose-dependent analgesic effect in mice pain models.

  Fitoterapia, 2012

• Topical green tea extract significantly improved clinical symptoms, tear breakup times, and meibomian gland health compared to standard treatment in patients with dry eye and Meibomian Gland Dysfunction.

  Journal of Clinical and Diagnostic Research, 2017

• Topical low-dose green tea extract reduces UVB-induced p53 expression and apoptosis in human skin keratinocytes compared to placebo.

  Experimental Dermatology, 2009

• An anti-acne hydrogel containing Aloe barbadensis, Garcinia mangostana, and Camellia sinensis extracts showed superior antiacne and antiblotch activities compared to 1% clindamycin gel in sixty subjects with mild-moderate acne.

  Clinical, Cosmetic and Investigational Dermatology, 2019

Ingredients

Water, Glycerin, Cyclopentasiloxane, Polysilicone-11, Pentaerythrityl Tetraethylhexanoate, Dipropylene Glycol, Methyl Methacrylate Crosspolymer, Betaine, Bis-Peg Ppg-16 16 Dimethicone, Sodium Hyaluronate, Evodia Rutaecarpa Fruit Extract, Albizia Julibrissin Bark Extract, Caprylic Capric Triglyceride, Sea Whip Extract, Hydrolyzed Soy Flour, Camellia Sinensis Leaf Extract, Hydroxyethylacrylate Sodium Acryloyldimethyl Taurate Copolymer, Mica, Isohexadecane, Ceteareth-33, Titanium Dioxide, Decylene Glycol, Magnesium Aluminum Silicate, Xanthan Gum, Dimethicone, Polysorbate 50, Butylene Glycol, Hydroxypropyl Cyclodextrin, Sorbitan Isostearate, Triethyl Citrate, Lavandula Angustifolia Stem Extract Flower Leaf Lavender Stem Extract Flower Leaf, Propanediol, Cyclohexasiloxane, Sodium Benzoate, Elettaria Cardamomum Seed Extract, Pyrus Malus Fruit Extract, Rubus Idaeus Fruit Extract Raspberry Fruit Extract, 2-Hexanediol, Disodium Edta, Phenoxyethanol, Iodopropynyl Butylcarbamate

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.