# make p:rem UV Defense Me. Calming Sun Cream SPF 50 for sensitive skin

**Lovi Fit: Superior fit for sensitive skin.**
Normal Skin Fit: Superior · Effectiveness: Superior · Safety: Excellent.

Page: https://lovi.care/skincare/uk/p/make-p-rem/uv-defense-me-calming-sun-cream-spf-50/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [make p:rem](https://lovi.care/skincare/uk/brands/make-p-rem)
Category: [Sunscreens and SPF moisturizers](https://lovi.care/skincare/uk/best/sunscreens)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best sunscreens for sensitive skin.

## Why this fit

- Excellent suitability for your normal skin and goals of reducing redness and irritation is provided by the high concentration of zinc oxide for UV protection, alongside Madecassoside and Cardiospermum Halicacabum Vine Extract Flower Leaf for targeted soothing and anti-inflammatory effects.
- Sodium Hyaluronate and Moringa Oleifera Seed Extract further enhance hydration and skin barrier support, complementing the calming properties for overall skin comfort.
- The formulation is exceptionally safe for your sensitive skin, free from harsh ingredients and enriched with soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/make-p-rem/uv-defense-me-calming-sun-cream-spf-50/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/uk/p/make-p-rem/uv-defense-me-calming-sun-cream-spf-50/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/uk/p/make-p-rem/uv-defense-me-calming-sun-cream-spf-50/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/uk/p/make-p-rem/uv-defense-me-calming-sun-cream-spf-50/for/sensitive-skin): Superior (this page)
- [Acne-prone skin](https://lovi.care/skincare/uk/p/make-p-rem/uv-defense-me-calming-sun-cream-spf-50/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/uk/p/make-p-rem/uv-defense-me-calming-sun-cream-spf-50/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/uk/p/make-p-rem/uv-defense-me-calming-sun-cream-spf-50/for/mature-skin): Superior
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/make-p-rem/uv-defense-me-calming-sun-cream-spf-50/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/make-p-rem/uv-defense-me-calming-sun-cream-spf-50/for/oily-acne-prone-skin): High

## Key ingredients

Zinc Oxide, Sodium Hyaluronate, Madecassoside, Moringa Oleifera Seed Extract, Cardiospermum Halicacabum Extract

## What the research says

- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Emulgels containing Perilla frutescens seed oil, Moringa oleifera seed oil, and mixed seed oil microemulsions exhibit good stability, lack of cytotoxicity in PBMC, and no skin irritation or allergic reactions in human subjects. ([Polymers, 2022](https://pubmed.ncbi.nlm.nih.gov/35745923/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical 0.5% hyaluronic-ZnO nanogel applied twice daily reduced inflammatory-lesion counts by 58% at week four in human subjects compared to baseline without causing erythema. ([Biomedicines, 2025](https://pubmed.ncbi.nlm.nih.gov/41007718/))
- Nels cream achieved a similar reduction in inflammatory and noninflammatory lesion counts compared to 5% benzoyl peroxide in acne vulgaris patients, but caused significantly fewer side-effects such as peeling and dryness. ([Clinical and Experimental Dermatology, 2000](https://pubmed.ncbi.nlm.nih.gov/10671963/))
- Topically applied coated and uncoated zinc oxide nanoparticles under flexing and massage are retained in the stratum corneum with no significant penetration into the viable epidermis and no cellular toxicity in human skin. ([Nanomedicine, 2016](https://pubmed.ncbi.nlm.nih.gov/27102240/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Treatment with an asiaticoside-containing cream applied twice daily for 12 weeks significantly improved periorbital wrinkles in 65% of 27 female volunteers compared to a vehicle control cream. ([International Journal of Cosmetic Science, 2008](https://pubmed.ncbi.nlm.nih.gov/18452433/))
- Aqueous standardized leaf extracts of Moringa oleifera showed the highest human dermal fibroblast and human keratinocyte proliferation and migration properties, leading to the development of an alginate-pectin film dressing with optimal physicochemical properties. ([Journal of Ethnopharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/29080829/))
- Topical administration of Moringa oleifera seed extract on excision wounds in male albino rabbits significantly increased the wound healing rate, elevated TGF-β1, VEGF, and Type I collagen relative expression, and reduced inflammatory markers like IL-1β and TNF-α compared to untreated and MEBO-treated groups. ([Antioxidants, 2022](https://pubmed.ncbi.nlm.nih.gov/36139817/))
- Moringa oleifera leaf extracts provided significant UV protection with an SPF of 2 at 2% to 4% concentrations and showed no significant irritant potential in cosmetic formulations. ([Molecules, 2018](https://pubmed.ncbi.nlm.nih.gov/29543741/))
- Pretreatment with Cardiospermum halicacabum extract ameliorated UVB-triggered cellular senescence, inhibited intracellular ROS generation, restored mitochondrial respiratory function, and suppressed the hyperactivation of the PI3K/Akt/mTOR signaling cascade in human skin fibroblasts. ([International Journal of Molecular Sciences, 2026](https://pubmed.ncbi.nlm.nih.gov/41828529/))

## What reviewers say

This physical sunscreen is highly praised by users with sensitive skin for its gentle, non-irritating formula featuring soothing ingredients like bamboo water and madecassoside. Its 100% zinc oxide composition frequently results in a noticeable white cast, particularly on darker skin tones, and some users with dry skin report it can feel tight or cling to dry patches throughout the day.

- Liked: Gentle & Non-Irritating (mostly mentioned)
- Disliked: Visible white cast (mostly mentioned)
- Liked: Non-Sticky Finish (often mentioned)
- Liked: Creamy Texture (sometimes noted)
- Liked: Eye Friendly (sometimes noted)
- Disliked: Drying sensation (sometimes noted)
- Disliked: Difficult removal (rarely noted)
- Disliked: Greasy/Shiny (rarely noted)

## How to apply

- Apply this sunscreen during your AM routine every morning. Reapply every two hours if you are staying outdoors under direct sunlight.
- Order in routine: apply the sunscreen as the final step after your moisturizer and before applying makeup.
- Application method: gently press a nickel-sized amount over your face and neck without harsh rubbing.
- Skin condition guidance: apply the sunscreen directly onto dry skin for even coverage and reliable sun protection.
- Safety note: avoid direct contact with your eyes and do a patch test before first use to check for sensitivity.
- Video: https://storage.pora.ai/53e9a436d82fca2a189dd08aa21de2fd.mp4

## Questions and answers

### What makes make p:rem Calming Sun Cream one of the best fits for sensitive skin?

This sunscreen is one of the best fits for sensitive skin because it relies on a high concentration of zinc oxide for sun protection alongside soothing ingredients like madecassoside and cardiospermum halicacabum extract to help calm redness and irritation. It also features sodium hyaluronate and moringa seed extract to boost hydration and support your skin barrier, all within a very safe formula free from harsh additives.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Which ingredients make this cream a good fit for sensitive skin?

This cream is a great fit for sensitive skin because it uses zinc oxide for sun protection alongside madecassoside and cardiospermum halicacabum extract to help soothe redness and irritation. Sodium hyaluronate and moringa seed extract add extra hydration and support your skin barrier for all-day comfort.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### What does Zinc Oxide do for sensitive skin?

Zinc oxide helps calm red, irritated skin and protects against irritation while being gentle enough for daily use. It is unlikely to cause trouble for delicate areas, making it a safe choice for soothing sensitive skin.
Sources: [Journal of Controlled Release, 2025](https://pubmed.ncbi.nlm.nih.gov/40254135/), [Biomedicines, 2025](https://pubmed.ncbi.nlm.nih.gov/41007718/)

### What does Hyaluronic Acid do for sensitive skin?

Hyaluronic acid helps calm and hydrate sensitive skin while supporting the skin barrier to keep it soft and comfortable. Clinical studies show it improves surface moisture and reduces dryness, roughness, and redness without irritation.
Sources: [Journal of Drugs in Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41037531/), [Journal of Cosmetic Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29356277/)

### Where does this cream go in a skincare routine for sensitive skin?

This cream goes in your morning routine as the final moisturizing sun protection step, applied after your soothing toner. It is exceptionally safe for sensitive skin and helps calm redness and irritation.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can I use this cream with retinol, and in what order?

You can use this sunscreen in the morning as the final step of your routine when using retinol at night. It is exceptionally safe for sensitive skin and helps keep your face calm and hydrated while you use strong treatments.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### How often should I use this cream?

You can use this sunscreen every morning as the final step of your daytime routine. Its gentle, soothing ingredients and high safety profile make it well suited for daily use on sensitive skin.
Sources: [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36607762/)

### Can this cream clog pores, cause breakouts or purging for sensitive skin?

This cream is unlikely to clog pores or cause breakouts for sensitive skin because it relies on zinc oxide and soothing plant extracts that help calm irritation without heavy oils. However, since it is a mineral sunscreen, it may leave a visible white cast.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [Clinique Mineral Sunscreen Fluid for Face SPF 50](https://lovi.care/skincare/uk/p/clinique/broad-spectrum-spf-50-mineral-sunscreen-fluid-for-face/for/sensitive-skin) — Superior fit — £21.00 at Amazon
- [Real Barrier Mild Sun Cream](https://lovi.care/skincare/uk/p/real-barrier/mild-sun-cream/for/sensitive-skin) — High fit — £19.01 at Amazon
- [Missha All Around Safe Block Soft Finish Sun Milk SPF 50+](https://lovi.care/skincare/uk/p/missha/all-around-safe-block-soft-finish-sun-milk/for/sensitive-skin) — High fit — £14.69 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/uk/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — £14.99 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/uk/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — £17.91 at Amazon
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/uk/p/missha/ultra-hyalon-cleansing-cream/for/sensitive-skin) — Superior fit — £13.58 at Amazon

## Where to buy

- Amazon.co.uk: £19.68 (https://www.amazon.co.uk/dp/B0CF22FB86?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Zinc Oxide, Cyclohexasiloxane, Butyloctyl Salicylate, Propanediol, Propylheptyl Caprylate, Isododecane, Polyglyceryl-3 Polydimethylsiloxyethyl Dimethicone, Caprylyl Methicone, Disiloxane, Moringa Oleifera Seed Extract, Cardiospermum Halicacabum Vine Extract Flower Leaf, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Sodium Hyaluronate, Bambusa Vulgaris Water, Ribes Nigrum Seed Oil, Helianthus Annuus Seed Oil Sunflower Seed Oil, Madecassoside, Fructan, Biosaccharide Gum-4, Pyrus Communis Fruit Extract, Prunus Persica Fruit Extract, Cucumis Melo Fruit Extract, Hedera Helix Stem Extract Leaf, Rosa Damascena Flower Water, Jasmine Flower Water, Disteardimonium Hectorite, Magnesium Sulfate, Triethoxycaprylylsilane, 1,2-Hexanediol, Polyglyceryl-2 Dipolyhydroxystearate, Polymethylsilsesquioxane, Lauryl Polyglyceryl-3 Polydimethylsiloxyethyl Dimethicone, Glyceryl Caprylate, Caprylyl Glycol, Ethylhexylglycerin, Tocopherol, Octyldodecanol, Maltodextrin, Butylene Glycol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/make-p-rem/uv-defense-me-calming-sun-cream-spf-50/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/make-p-rem/uv-defense-me-calming-sun-cream-spf-50/for/sensitive-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/make-p-rem/uv-defense-me-calming-sun-cream-spf-50/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/make-p-rem/uv-defense-me-calming-sun-cream-spf-50/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/make-p-rem/uv-defense-me-calming-sun-cream-spf-50/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/make-p-rem/uv-defense-me-calming-sun-cream-spf-50/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/make-p-rem/uv-defense-me-calming-sun-cream-spf-50/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/make-p-rem/uv-defense-me-calming-sun-cream-spf-50/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/make-p-rem/uv-defense-me-calming-sun-cream-spf-50/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/make-p-rem/uv-defense-me-calming-sun-cream-spf-50/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/make-p-rem/uv-defense-me-calming-sun-cream-spf-50/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/make-p-rem/uv-defense-me-calming-sun-cream-spf-50/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/make-p-rem/uv-defense-me-calming-sun-cream-spf-50/for/sensitive-skin