# La Roche-Posay PURE VITAMIN C12 SÉRUM for oily acne-prone skin

**Lovi Fit: Average fit for oily acne-prone skin.**
Oily Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/uk/p/la-roche-posay/pure-vitamin-c12-serum/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [La Roche-Posay](https://lovi.care/skincare/uk/brands/la-roche-posay)
Category: [Serums and treatments](https://lovi.care/skincare/uk/best/serums)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily acne-prone skin; other serums fit it better.

## Why this fit

- Offers moderate brightening for your oily skin due to ascorbic acid, which aids in evening skin tone and provides antioxidant activity, complemented by glycerin for humectant action.
- Hyaluronic acid and tocopherol offer general hydration and supportive benefits for your oily skin and acne concerns, though specialized ingredients for directly targeting acne are absent.
- The formulation is safe for your oily skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/la-roche-posay/pure-vitamin-c12-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/uk/p/la-roche-posay/pure-vitamin-c12-serum/for/dry-skin): Caution
- [Combination skin](https://lovi.care/skincare/uk/p/la-roche-posay/pure-vitamin-c12-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/uk/p/la-roche-posay/pure-vitamin-c12-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/uk/p/la-roche-posay/pure-vitamin-c12-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/uk/p/la-roche-posay/pure-vitamin-c12-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/uk/p/la-roche-posay/pure-vitamin-c12-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/la-roche-posay/pure-vitamin-c12-serum/for/dry-sensitive-skin): Caution
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/la-roche-posay/pure-vitamin-c12-serum/for/oily-acne-prone-skin): Average (this page)

## Key ingredients

Ascorbic Acid, Glycerin, Hyaluronic Acid

## What the research says

- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))
- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## Why other serums fit oily acne-prone skin better

- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))

## What reviewers say

Users consistently praise the serum for its ability to smooth skin texture and boost radiance, often noting it absorbs quickly without leaving a sticky residue. While many with sensitive skin find the formula gentle and effective for brightening, some users express frustration with the product oxidizing too quickly and the dropper design leading to wastage.

- Liked: Improves texture (often mentioned)
- Liked: Lightweight feel (often mentioned)
- Liked: Gentle formula (sometimes noted)
- Liked: Pleasant scent (sometimes noted)
- Disliked: High price (sometimes noted)
- Disliked: Oxidizes quickly (sometimes noted)
- Disliked: Poor dropper (sometimes noted)
- Disliked: Strong scent (rarely noted)

## How to apply

- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does La Roche-Posay Pure Vitamin C12 work for oily acne-prone skin?

This serum offers moderate brightening and hydration for your oily skin with vitamin C and glycerin, though it lacks specialized ingredients for directly targeting acne. A treatment of this type needs effective ingredients like niacinamide and propolis that provide excellent skincare benefits for acne, excess oil, and uneven texture without any risk of irritation.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/)

### Which ingredients make this serum a good fit for oily acne-prone skin?

Ascorbic acid helps brighten your oily skin and even out its tone, while glycerin and hyaluronic acid provide light hydration without heaviness. To be a better fit for this skin type, a treatment of this type needs specialized acne-fighting ingredients like niacinamide or propolis alongside soothing extracts for daily comfort and oil control.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/)

### What does Vitamin C do for oily acne-prone skin?

Vitamin C helps brighten skin, smooth out texture, and improve uneven spots for oily acne-prone skin. It may also help fade marks left behind by blemishes.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/)

### What does Glycerin do for oily acne-prone skin?

Glycerin helps keep oily acne-prone skin hydrated without feeling heavy. It draws moisture into the skin while supporting the skin barrier so it stays soft and balanced.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Where does this serum go in a skincare routine for oily acne-prone skin?

This treatment serum goes in the evening routine after cleansing and before moisturizing, which keeps the application simple and safe around sun exposure. To properly care for oily acne-prone skin, this type of product also needs specialized ingredients that directly target breakouts and blemishes.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol, but it is best to apply them at different times of day or alternate nights to avoid irritation. Since this contains vitamin C, use it in your morning routine and save your retinol for the evening routine. This helps your skin stay bright and smooth while lowering the chances of redness or discomfort.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/)

### How often should I use this serum?

You can use this treatment serum in your evening routine, as suggested for simplicity and extra safety around sun exposure. This product works for your oily skin, though an oily acne-prone skin needs a product with specialized ingredients to directly target acne.

### Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?

This serum is unlikely to clog pores or cause breakouts for your oily skin because it has a safe formula without harsh ingredients, but a product of this type needs specialized acne-fighting ingredients to directly target breakouts.

### Is this serum fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (alcohol denat).

## Alternatives for oily acne-prone skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/uk/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/oily-acne-prone-skin) — Superior fit — £36.96 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/uk/p/neogen-dermalogy/real-vitamin-c-serum/for/oily-acne-prone-skin) — Superior fit — £25.95 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/uk/p/neogen-dermalogy/real-vita-c-serum/for/oily-acne-prone-skin) — High fit — £25.95 at Amazon

## Pairs well with

- Cleanser: [Paula's Choice CLEAR Pore Normalizing Cleanser](https://lovi.care/skincare/uk/p/paula-s-choice/clear-pore-normalizing-cleanser/for/oily-acne-prone-skin) — Superior fit — £26.00 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/uk/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — £30.37 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/uk/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-acne-prone-skin) — Superior fit — £14.80 at Amazon

## Where to buy

- Amazon.co.uk: £33.75 (https://www.amazon.co.uk/dp/B07PM79MSC?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: £33.75 (https://www.lookfantastic.com/p/la-roche-posay-vitamin-c12-serum-anti-wrinkle-and-radiance-restoring-serum-30ml/15456549/)
- Notino: £44.20 (https://www.notino.co.uk/la-roche-posay/pure-vitamin-c-vitamin-c-brightening-serum-with-anti-wrinkle-effect/p-16269149/)
Prices checked 17 Oct – 6 Nov 2026.

## Ingredients

Water, Ascorbic Acid, Glycerin, Alcohol Denat, Propylene Glycol, Pentylene Glycol, Polysorbate 20, Sodium Hydroxide, Hyaluronic Acid, Adenosine, Caprylyl Glycol, Hydrolyzed Hyaluronic Acid, Xanthan Gum, Tocopherol, Phenoxyethanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/la-roche-posay/pure-vitamin-c12-serum/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/la-roche-posay/pure-vitamin-c12-serum/for/oily-acne-prone-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/la-roche-posay/pure-vitamin-c12-serum/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/la-roche-posay/pure-vitamin-c12-serum/for/oily-acne-prone-skin
- France: https://lovi.care/skincare/fr/p/la-roche-posay/pure-vitamin-c12-serum/for/oily-acne-prone-skin
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