# La Roche-Posay Pure Vitamin C10 Serum for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/uk/p/la-roche-posay/pure-vitamin-c10-serum/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [La Roche-Posay](https://lovi.care/skincare/uk/brands/la-roche-posay)
Category: [Serums and treatments](https://lovi.care/skincare/uk/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other serums fit it better.

## Why this fit

- Offers moderate brightening and smoothing for your combination skin, as ascorbic acid and salicylic acid work to even skin tone and decongest pores. Glycerin provides humectant action to balance oily and dry areas.
- The serum offers general skincare benefits like hydration and mild exfoliation, supporting your goal of managing oily shine.
- The product is safe for your combination skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/la-roche-posay/pure-vitamin-c10-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/uk/p/la-roche-posay/pure-vitamin-c10-serum/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/uk/p/la-roche-posay/pure-vitamin-c10-serum/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/uk/p/la-roche-posay/pure-vitamin-c10-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/uk/p/la-roche-posay/pure-vitamin-c10-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/uk/p/la-roche-posay/pure-vitamin-c10-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/uk/p/la-roche-posay/pure-vitamin-c10-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/la-roche-posay/pure-vitamin-c10-serum/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/la-roche-posay/pure-vitamin-c10-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Ascorbic Acid, Neurosensine, Salicylic Acid, Sodium Hyaluronate, Thermal Spring Water

## What the research says

- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Twice daily application of a multitargeted dermocosmetic cream provided comparable efficacy to benzoyl peroxide 5% gel in reducing inflammatory, non-inflammatory, and total lesions in 150 Caucasian subjects with mild-to-moderate acne over 56 days, while demonstrating superior skin tolerability. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/))
- A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase. ([BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/))
- The use of a salicylic acid-based dermocosmetic significantly reduces the needed quantity of benzoyl peroxide without impacting efficacy in mild to moderate acne, and as maintenance post-benzoyl peroxide allows a significant reduction of acne relapse compared to vehicle. ([Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/38051857/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Cryotherapy with liquid nitrogen achieved a higher cure rate (39%) than salicylic acid (24%) and a wait-and-see approach (16%) for cutaneous warts at 13 weeks in primary care patients. ([CMAJ, 2010](https://pubmed.ncbi.nlm.nih.gov/20837684/))
- Treatment with 2% supramolecular salicylic acid hydrogel resulted in a regression and markedly improvement rate of 51.01% compared to 43.10% for Adapaline gel in patients with mild to moderate facial acne vulgaris, showing no significant difference in efficacy. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590107/))
- Topical 5% benzoyl peroxide plus salicylic acid achieved the greatest lesion reduction at early 2 to 4 week time points compared to benzoyl peroxide, clindamycin, and combination benzoyl peroxide/clindamycin, while 5% benzoyl peroxide plus salicylic acid and combination benzoyl peroxide/clindamycin showed similar efficacy at 10 to 12 weeks in acne patients. ([Journal of the American Academy of Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20488582/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Balneotherapy with thermal water altered specific skin microbiota at genus and species levels in healthy female volunteers compared to tap water, which produced no significant microbiome changes. ([Life, 2023](https://pubmed.ncbi.nlm.nih.gov/36983902/))
- Malaysian thermal spring water as an adjunct to standard acne therapy improved skin hydration, reduced dryness and stinging, enhanced overall tolerability, and improved the acne disability index in patients with mild to moderate acne. ([The Medical Journal of Malaysia, 2024](https://pubmed.ncbi.nlm.nih.gov/38553920/))
- A 2% Sphingomonas xenophaga ferment extract cream applied twice daily for 4 weeks significantly decreased facial vascular disorder scores compared to vehicle in 86 Caucasian female subjects, alongside dose-dependent inhibition of pre-kallikrein activity in vitro. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/40545753/))

## What reviewers say

Based on a very large amount of data, this serum is frequently praised for visibly brightening dull complexions and smoothing skin texture, leaving skin feeling softer and more hydrated. However, a very high number of users report that the formula oxidizes quickly, turning orange, and a high number find the texture sticky and difficult to layer. Moderate numbers of users also mention a strong fragrance and issues with the dropper packaging.

- Disliked: Oxidizes quickly (mostly mentioned)
- Liked: Brightens and adds radiance (often mentioned)
- Liked: Smoothes skin texture (often mentioned)
- Disliked: Unpleasant texture (often mentioned)
- Liked: Gentle for many (sometimes noted)
- Liked: Hydrating formula (sometimes noted)
- Disliked: Poor packaging (sometimes noted)
- Disliked: Strong fragrance (sometimes noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does La Roche-Posay Pure Vitamin C10 work for combination skin?

La Roche-Posay Pure Vitamin C10 Serum is an average fit for combination skin, offering moderate brightening, smoothing, and hydration while helping balance oily and dry areas. Treatments that fit combination skin better need ingredients like niacinamide, propolis, and zinc PCA to regulate oiliness and provide optimal hydration without overwhelming oilier areas.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for combination skin?

This serum works for combination skin because ascorbic acid and salicylic acid help even skin tone and clear pores, while glycerin balances oily and dry areas. To fit this skin type even better, products need ingredients like niacinamide, propolis, or zinc PCA to regulate oiliness and boost radiance without causing irritation.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Vitamin C do for combination skin?

Vitamin C helps brighten dull areas and smooth out uneven texture on combination skin while protecting against daily environmental stress. It may also help keep pores clear and skin firm by supporting collagen production, though drier spots may need an added moisturizer to stay comfortable.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/), [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37128827/)

### What does Neurosensine do for combination skin?

Neurosensine helps calm sensitive skin and reduces stinging, making it a comforting choice for combination skin. Because combination skin often gets irritated easily in certain areas, this ingredient is unlikely to cause trouble and may help soothe redness and discomfort.
Sources: [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38899754/), [Journal of the European Academy of Dermatology and Venereology, 2016](https://pubmed.ncbi.nlm.nih.gov/26805418/)

### Where does this serum go in a skincare routine for combination skin?

This serum goes in the evening routine after cleansing and before moisturizing. Combination skin works best with a treatment that pairs ascorbic acid and salicylic acid for brightening and decongesting pores while glycerin balances oily and dry areas.

### Can I use it with niacinamide, and in what order?

You can use this serum with niacinamide by applying niacinamide first and letting it absorb before putting on this treatment. Combining them helps brighten your skin tone and manage oily shine without causing irritation. To get a better fit for your combination skin, this type of product needs extra soothing ingredients and deep hydration to balance both oily and dry areas.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### How often should I use this serum?

You can use this serum in your evening routine once a week to start, and carefully use it more often if your skin tolerates it well. This type of skin needs a treatment that balances oily and dry areas with ingredients like vitamin C, salicylic acid, and glycerin to brighten skin and manage shine.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can it clog pores, cause breakouts or purging for combination skin?

This serum is unlikely to clog pores or cause breakouts on combination skin, as it contains salicylic acid to help clear out pores and keep skin smooth. However, because it is only an average fit for this skin type, combination skin often needs a lightweight formula with balanced hydrators and gentle exfoliants to manage oily shine without heavy layers.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/), [BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/)

### Is this serum fragrance-free and alcohol-free?

It contains fragrance (parfum) and drying alcohol (alcohol denat).

## Alternatives for combination skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/uk/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/combination-skin) — Superior fit — £36.96 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/uk/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin) — Superior fit — £24.20 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/uk/p/augustinus-bader/the-serum/for/combination-skin) — Superior fit — £248.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/uk/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — £14.99 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/uk/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — £30.37 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/uk/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — £14.80 at Amazon

## Where to buy

- Amazon.co.uk: £54.54 (https://www.amazon.co.uk/dp/B07QL32ZLR?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Ascorbic Acid, Cyclohexasiloxane, Glycerin, Alcohol Denat, Potassium Hydroxide, Polymethylsilsesquioxane, Polysilicone-11, Dimethicone, Propylene Glycol, Pentaerythrityl Tetraethylhexanoate, C13-14 Isoparaffin, Peg-20 Methyl Glucose Sesquistearate, Sodium Hyaluronate, Adenosine, Poloxamer 338, Ammonium Polyacryloyldimethyl Taurate, Disodium Edta, Hydrolyzed Hyaluronic Acid, Caprylyl Glycol, Laureth-7, Acetyl Dipeptide-1 Cetyl Ester, Xanthan Gum, Toluene Sulfonic Acid, Polyacrylamide, Tocopherol, Salicylic Acid, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/la-roche-posay/pure-vitamin-c10-serum/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/la-roche-posay/pure-vitamin-c10-serum/for/combination-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/la-roche-posay/pure-vitamin-c10-serum/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/la-roche-posay/pure-vitamin-c10-serum/for/combination-skin
- France: https://lovi.care/skincare/fr/p/la-roche-posay/pure-vitamin-c10-serum/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/la-roche-posay/pure-vitamin-c10-serum/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/la-roche-posay/pure-vitamin-c10-serum/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/la-roche-posay/pure-vitamin-c10-serum/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/la-roche-posay/pure-vitamin-c10-serum/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/la-roche-posay/pure-vitamin-c10-serum/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/la-roche-posay/pure-vitamin-c10-serum/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/la-roche-posay/pure-vitamin-c10-serum/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/la-roche-posay/pure-vitamin-c10-serum/for/combination-skin