# La Roche-Posay Mela B3 Serum for dry skin

**Lovi Fit: Average fit for dry skin.**
Dry Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/uk/p/la-roche-posay/mela-b3-serum/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [La Roche-Posay](https://lovi.care/skincare/uk/brands/la-roche-posay)
Category: [Serums and treatments](https://lovi.care/skincare/uk/best/serums)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry skin; other serums fit it better.

## Why this fit

- Offers moderate suitability for dry skin as glycerin and sodium hyaluronate provide humectant action, while niacinamide and capryloyl salicylic acid work to improve skin tone and texture.
- The formula provides general skincare benefits like hydration, which is supportive for dry or flaky skin, but lacks specialized ingredients to directly address the core concern of dryness.
- The safety profile is excellent, with no risks of irritation for your dry skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/la-roche-posay/mela-b3-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/uk/p/la-roche-posay/mela-b3-serum/for/dry-skin): Average (this page)
- [Combination skin](https://lovi.care/skincare/uk/p/la-roche-posay/mela-b3-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/uk/p/la-roche-posay/mela-b3-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/uk/p/la-roche-posay/mela-b3-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/uk/p/la-roche-posay/mela-b3-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/uk/p/la-roche-posay/mela-b3-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/la-roche-posay/mela-b3-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/la-roche-posay/mela-b3-serum/for/oily-acne-prone-skin): High

## Key ingredients

Niacinamide, La Roche-Posay Thermal Spring Water, Melasyl, Cystoseira Tamariscifolia Extract, Sodium Hyaluronate

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Treatment with a combination of niacinamide and hyaluronic acid improved skin aging signs and demonstrated a senomorphic effect by decreasing SASP and autocrine signaling genes in women. ([Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/))
- Avène Thermal Spring Water significantly decreased postpeeling redness and reduced the overall sensitive scale of consumers by 47% compared to mineral-rich thermal spring water in human volunteers. ([Journal of the European Academy of Dermatology and Venereology, 2020](https://pubmed.ncbi.nlm.nih.gov/32870553/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Balneotherapy with thermal water altered specific skin microbiota at genus and species levels in healthy female volunteers compared to tap water, which produced no significant microbiome changes. ([Life, 2023](https://pubmed.ncbi.nlm.nih.gov/36983902/))
- Malaysian thermal spring water as an adjunct to standard acne therapy improved skin hydration, reduced dryness and stinging, enhanced overall tolerability, and improved the acne disability index in patients with mild to moderate acne. ([The Medical Journal of Malaysia, 2024](https://pubmed.ncbi.nlm.nih.gov/38553920/))
- A 2% Sphingomonas xenophaga ferment extract cream applied twice daily for 4 weeks significantly decreased facial vascular disorder scores compared to vehicle in 86 Caucasian female subjects, alongside dose-dependent inhibition of pre-kallikrein activity in vitro. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/40545753/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## Why other serums fit dry skin better

- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))

## What reviewers say

Based on a very large amount of data, users frequently praise this serum for its lightweight, non-sticky texture and its ability to fade post-acne marks and sun spots over time. Many report brighter, more even skin tone within a few weeks. A notable portion of reviewers found the results slow or nonexistent for stubborn hyperpigmentation and complained about the strong floral fragrance.

- Liked: Good texture (mostly mentioned)
- Liked: Brightens skin (often mentioned)
- Liked: Fades dark spots (often mentioned)
- Disliked: Strong fragrance (often mentioned)
- Liked: Gentle on skin (sometimes noted)
- Disliked: Ineffective for some (sometimes noted)
- Disliked: Caused irritation (rarely noted)
- Disliked: High price (rarely noted)

## How to apply

- Apply this serum PM, starting 3×/week and working up to daily use as your skin adjusts.
- Place the serum after cleansing and toner, but right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on slightly damp skin to help lock in extra moisture.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does La Roche-Posay Mela B3 work for dry skin?

La Roche-Posay Mela B3 Serum offers moderate suitability for dry skin because it provides general hydration, though other products fit this skin type better. To work well for dry skin, this type of product needs soothing ingredients that provide significant moisture and support the skin barrier, such as ceramides, propolis, or bifida fermentation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for dry skin?

This serum works for dry skin because glycerin and sodium hyaluronate draw in moisture, while niacinamide helps even out your skin tone. It also has a safe formula that is unlikely to cause irritation. Dry skin needs products rich in deeply nourishing ingredients, ceramides, and strong barrier support to keep it soft and smooth.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/)

### What does Niacinamide do for dry skin?

Niacinamide helps dry skin by strengthening the skin barrier, increasing hydration, and reducing water loss. It supports ceramide production and helps keep the surface smooth and calm. This ingredient tends to be very well tolerated and is unlikely to irritate dry skin.
Sources: [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/), [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/42108609/)

### What does Thermal Spring Water do for dry skin?

Thermal spring water helps keep dry skin calm and hydrated by reducing redness and soothing irritation. Regular use may also improve skin moisture levels and help make the skin feel much softer.
Sources: [The Medical Journal of Malaysia, 2024](https://pubmed.ncbi.nlm.nih.gov/38553920/), [Journal of the European Academy of Dermatology and Venereology, 2020](https://pubmed.ncbi.nlm.nih.gov/32870553/)

### Where does it go in a skincare routine for dry skin?

This treatment goes in the evening routine after cleansing and before moisturizing. Dry skin needs rich creams and oils with nourishing plant butters or ceramides to lock in moisture and soothe flaky areas.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first and following it with your retinol treatment. This combination is unlikely to cause irritation due to the formula's very safe profile, but dry skin needs richer hydrating ingredients and heavy moisturizing creams to lock in moisture.

### How often should I use it?

This treatment works well in the evening as part of your routine for dry skin. To properly care for dry skin, products of this type need rich moisturizing oils, butters, and barrier-repairing ceramides to lock in hydration and stop flaking.

### Can this serum clog pores, cause breakouts or purging for dry skin?

This serum is unlikely to cause breakouts or clogged pores for dry skin, as its safety profile is excellent and it lacks harsh ingredients. It brings moderate hydration with glycerin and sodium hyaluronate, though dry skin generally needs richer ingredients to fully address dryness.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is it fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum).

## Alternatives for dry skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/uk/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/dry-skin) — Superior fit — £36.96 at Amazon
- [KraveBeauty Great Barrier Relief](https://lovi.care/skincare/uk/p/kravebeauty/great-barrier-relief/for/dry-skin) — Superior fit — £32.95 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/uk/p/augustinus-bader/the-serum/for/dry-skin) — Superior fit — £248.00 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/uk/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — £8.29 at Amazon
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/uk/p/dear-klairs/supple-preparation-unscented-toner/for/dry-skin) — Superior fit — £11.49 at Amazon
- Moisturizer: [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/uk/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/dry-skin) — Superior fit — £14.74 at Amazon

## Where to buy

- Amazon.co.uk: £36.00 (https://www.amazon.co.uk/dp/B0CM4B43DZ?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- Notino: £31.50 (https://www.notino.co.uk/la-roche-posay/mela-b3-facial-serum-for-skin-with-hyperpigmentation/p-16327557/)
- Lookfantastic: £38.40 (https://www.lookfantastic.com/p/la-roche-posay-melab3-serum-intense-anti-dark-spot-serum-for-hyperpigmentation-30ml/15058248/)
Prices checked 10 Oct – 6 Nov 2026.

## Ingredients

Water, Dimethicone, Niacinamide, Glycerin, Propylene Glycol, Polysilicone-11, Silica, Bis-Peg Ppg-16 16 Peg Ppg-16 16 Dimethicone, Cystoseira Tamariscifolia Extract, 2-Mercaptonicotinoyl Glycine, Peg-20 Methyl Glucose Sesquistearate, Sodium Hyaluronate, Sodium Hydroxide, Sodium Thiosulfate, Carnosine, Poloxamer 338, Ammonium Polyacryloyldimethyl Taurate, Dipotassium Glycyrrhizate, Caprylic Capric Triglyceride, Capryloyl Salicylic Acid, Caprylyl Glycol, Citric Acid, Trisodium Ethylenediamine Disuccinate, Xanthan Gum, Pentylene Glycol, Octyldodecanol, Retinyl Palmitate, Tocopherol, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Phenoxyethanol, Ci 17200 Red 33, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/la-roche-posay/mela-b3-serum/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/la-roche-posay/mela-b3-serum/for/dry-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/la-roche-posay/mela-b3-serum/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/la-roche-posay/mela-b3-serum/for/dry-skin
- France: https://lovi.care/skincare/fr/p/la-roche-posay/mela-b3-serum/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/la-roche-posay/mela-b3-serum/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/la-roche-posay/mela-b3-serum/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/la-roche-posay/mela-b3-serum/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/la-roche-posay/mela-b3-serum/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/la-roche-posay/mela-b3-serum/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/la-roche-posay/mela-b3-serum/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/la-roche-posay/mela-b3-serum/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/la-roche-posay/mela-b3-serum/for/dry-skin