# La Roche-Posay Cicaplast B5 Soothing Repairing Spray for combination skin

**Lovi Fit: High fit for combination skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/uk/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [La Roche-Posay](https://lovi.care/skincare/uk/brands/la-roche-posay)
Category: [Serums and treatments](https://lovi.care/skincare/uk/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for combination skin.

## Why this fit

- Offers high suitability for your combination skin as panthenol and madecassoside work to repair your skin barrier and reduce inflammation, addressing your oily shine concerns.
- The moderate concentrations of these ingredients provide excellent skin barrier resilience and soothing effects.
- The safety profile is excellent due to the absence of harsh ingredients and the inclusion of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/uk/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/uk/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/combination-skin): High (this page)
- [Sensitive skin](https://lovi.care/skincare/uk/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/sensitive-skin): Superior
- [Acne-prone skin](https://lovi.care/skincare/uk/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/uk/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/dark-spots): Superior
- [Mature skin](https://lovi.care/skincare/uk/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/oily-acne-prone-skin): Superior

## Key ingredients

Panthenol, Madecassoside, Thermal Water, Glycerin, Copper Gluconate

## What the research says

- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Treatment with an asiaticoside-containing cream applied twice daily for 12 weeks significantly improved periorbital wrinkles in 65% of 27 female volunteers compared to a vehicle control cream. ([International Journal of Cosmetic Science, 2008](https://pubmed.ncbi.nlm.nih.gov/18452433/))
- Balneotherapy with thermal water altered specific skin microbiota at genus and species levels in healthy female volunteers compared to tap water, which produced no significant microbiome changes. ([Life, 2023](https://pubmed.ncbi.nlm.nih.gov/36983902/))
- Malaysian thermal spring water as an adjunct to standard acne therapy improved skin hydration, reduced dryness and stinging, enhanced overall tolerability, and improved the acne disability index in patients with mild to moderate acne. ([The Medical Journal of Malaysia, 2024](https://pubmed.ncbi.nlm.nih.gov/38553920/))
- A 2% Sphingomonas xenophaga ferment extract cream applied twice daily for 4 weeks significantly decreased facial vascular disorder scores compared to vehicle in 86 Caucasian female subjects, alongside dose-dependent inhibition of pre-kallikrein activity in vitro. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/40545753/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Zinc gluconate induced alpha2, alpha3, alphaV, and alpha6 integrins, copper gluconate induced alpha2, alpha6, and beta1, and manganese gluconate induced most studied integrins in cultured keratinocytes. ([The British Journal of Dermatology, 1999](https://pubmed.ncbi.nlm.nih.gov/10215764/))

## What reviewers say

Users frequently describe this spray as a go-to for compromised skin barriers, appreciating its ability to instantly calm redness and irritation without physical contact. It is highly effective for sensitive skin conditions and post-procedure healing, though some users note a slightly tacky finish and an occasionally aggressive spray.

- Liked: Touch-free application (mostly mentioned)
- Liked: Barrier repair healing (often mentioned)
- Liked: Instant soothing relief (often mentioned)
- Liked: Lightweight hydration (sometimes noted)
- Disliked: Aggressive spray (sometimes noted)
- Disliked: Sticky finish (sometimes noted)
- Disliked: Price to quantity (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes La Roche-Posay Cicaplast B5 Spray a great fit for combination skin?

La Roche-Posay Cicaplast B5 Soothing Repairing Spray is a great fit because panthenol and madecassoside work to repair your skin barrier and calm irritation while helping with oily shine. The gentle formula provides very good skin soothing effects and is safe for your skin type without harsh ingredients.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Which ingredients make this spray a good fit for combination skin?

Panthenol and madecassoside make this spray a great fit for your combination skin because they help repair your skin barrier and calm irritation while addressing oily shine. These ingredients improve skin moisture and reduce redness to keep your skin feeling soft and comfortable.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### What does Panthenol do for combination skin?

Panthenol helps balance combination skin by boosting moisture while keeping redness and irritation calm. It is unlikely to cause breakouts and may help repair the skin barrier safely.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29577586/)

### What does Madecassoside do for combination skin?

Madecassoside helps keep combination skin calm and hydrated while supporting the skin barrier. It may also improve moisture balance and reduce irritation in areas that tend to be dry or flaky.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Where does this spray go in a skincare routine for combination skin?

This treatment goes in the evening routine after cleansing and before moisturizing, which keeps the routine simple and protects skin from daytime sun. Using it this way helps panthenol and madecassoside repair your skin barrier and calm oily shine without harsh ingredients.

### Can I use this spray with retinol, and in what order?

Yes, you can use this spray with retinol by applying the retinol first, letting it absorb, and then using the spray to help calm and soothe your skin. This combination is unlikely to cause irritation because the formula is very gentle and free of harsh ingredients.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### How often should I use this spray?

You can use this spray in your evening routine as a treatment, and some treatments may also be used in the morning or twice a day. It helps soothe your skin and is very safe to use regularly because it lacks harsh ingredients.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Can this spray clog pores, cause breakouts or purging for combination skin?

This spray is unlikely to clog pores or cause breakouts for combination skin. It features soothing ingredients and a safe formula that calms irritation while keeping your skin feeling comfortable.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Is this spray fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [True Botanicals Nutrient Mist](https://lovi.care/skincare/uk/p/true-botanicals/calm-nutrient-mist/for/combination-skin) — High fit — £148.35 at Amazon
- [BIOHEAL BOH Panthenol Cica Barrier Cream Mist](https://lovi.care/skincare/uk/p/bioheal-boh/panthenol-cica-barrier-cream-mist/for/combination-skin) — High fit — £18.99 at Amazon
- [Mario Badescu Facial Spray with Aloe, Chamomile and Lavender](https://lovi.care/skincare/uk/p/mario-badescu/facial-spray-with-aloe-chamomile-and-lavender/for/combination-skin) — High fit — £8.95 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/uk/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — £14.99 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/uk/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — £30.37 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/uk/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — £14.80 at Amazon

## Where to buy

- Amazon.co.uk: £11.99 (https://www.amazon.co.uk/dp/B09V1LBVZB?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: £16.50 (https://www.lookfantastic.com/p/la-roche-posay-cicaplast-b5-soothing-repairing-spray-100ml/13840295/)
- Notino: £19.40 (https://www.notino.co.uk/la-roche-posay/cicaplast-b5-soothing-spray-restorative-skin-barrier/p-16086395/)
Prices checked 10 Oct – 5 Nov 2026.

## Ingredients

Water, Glycerin, Propanediol, Panthenol, Pentylene Glycol, Sodium Citrate, Mannose, Madecassoside, Manganese Gluconate, Sodium Chloride, Coco-Betaine, Copper Gluconate, Caprylyl Glycol, Citric Acid, Trisodium Ethylenediamine Disuccinate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/combination-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/combination-skin
- France: https://lovi.care/skincare/fr/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/la-roche-posay/cicaplast-b5-soothing-repairing-spray/for/combination-skin