# La Roche-Posay Cicaplast B5 Serum for dry skin

**Lovi Fit: High fit for dry skin.**
Dry Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/uk/p/la-roche-posay/cicaplast-b5-serum/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [La Roche-Posay](https://lovi.care/skincare/uk/brands/la-roche-posay)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/uk/best/moisturizers)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for dry skin; a few moisturizers fit it even better.

## Why this fit

- Highly suitable for your dry skin due to the presence of panthenol and glycerin, which provide excellent moisturization and barrier repair, enhancing resilience against dryness and flakiness.
- The inclusion of dimethicone offers emollient action, further supporting skin hydration and smoothness for your dry skin type.
- The formulation is safe for your dry skin, as it contains no harsh ingredients that could cause irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/la-roche-posay/cicaplast-b5-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/uk/p/la-roche-posay/cicaplast-b5-serum/for/dry-skin): High (this page)
- [Combination skin](https://lovi.care/skincare/uk/p/la-roche-posay/cicaplast-b5-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/uk/p/la-roche-posay/cicaplast-b5-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/uk/p/la-roche-posay/cicaplast-b5-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/uk/p/la-roche-posay/cicaplast-b5-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/uk/p/la-roche-posay/cicaplast-b5-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/la-roche-posay/cicaplast-b5-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/la-roche-posay/cicaplast-b5-serum/for/oily-acne-prone-skin): High

## Key ingredients

B5 Panthenol, Thermal Water, Sodium Hyaluronate, Glycerin, Dimethicone

## What the research says

- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))
- Balneotherapy with thermal water altered specific skin microbiota at genus and species levels in healthy female volunteers compared to tap water, which produced no significant microbiome changes. ([Life, 2023](https://pubmed.ncbi.nlm.nih.gov/36983902/))
- Malaysian thermal spring water as an adjunct to standard acne therapy improved skin hydration, reduced dryness and stinging, enhanced overall tolerability, and improved the acne disability index in patients with mild to moderate acne. ([The Medical Journal of Malaysia, 2024](https://pubmed.ncbi.nlm.nih.gov/38553920/))
- A 2% Sphingomonas xenophaga ferment extract cream applied twice daily for 4 weeks significantly decreased facial vascular disorder scores compared to vehicle in 86 Caucasian female subjects, alongside dose-dependent inhibition of pre-kallikrein activity in vitro. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/40545753/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups. ([Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/))
- Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms. ([Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/))
- Externally applied substances such as ceramides, hyaluronic acid, licorice extracts, dimethicone, petrolatum, and paraffin wax treat skin disease resulting from damage to the skin barrier. ([Clinics in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22507050/))

## What reviewers say

This serum is widely praised as a rescue product for compromised skin barriers, effectively soothing redness, dehydration, and irritation. Most users with dry or sensitive skin report rapid healing and improved texture. A minority experience stinging upon application or find the formula too tacky and the dropper packaging messy.

- Liked: Intense barrier repair (mostly mentioned)
- Liked: Deep hydration (often mentioned)
- Liked: Soothing for sensitive skin (often mentioned)
- Disliked: Poor packaging design (often mentioned)
- Liked: Improves skin texture (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Unpleasant texture/finish (sometimes noted)
- Disliked: Caused irritation/stinging (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using it 3 times a week and work your way up to daily use.
- Apply your moisturizer after your toner and before your sunscreen in the morning. At night, use it as the final step after your serum.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing to keep your dry skin happy.
- Apply the moisturizer on slightly damp skin to help lock in extra hydration. This is great for soothing dry and flaky areas .
- Avoid the sensitive eye area and do a patch test before your first use .
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Cicaplast B5 Serum a great fit for dry skin?

La Roche-Posay Cicaplast B5 Serum is a great fit because ingredients like panthenol and glycerin help deeply moisturize dry skin and repair its protective barrier against flakiness. Additionally, dimethicone smooths the surface and helps lock in hydration, while the gentle formula is very unlikely to cause irritation.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Which ingredients make this serum a good fit for dry skin?

Panthenol and glycerin make this serum a great fit for dry skin by providing deep moisturization and repairing the skin barrier to protect against flakiness. Additionally, dimethicone smooths and softens the skin while locking in essential hydration.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Panthenol do for dry skin?

Panthenol helps dry skin by keeping it soft and holding onto moisture while repairing the skin barrier to reduce redness and roughness. It is well tolerated and improves overall hydration.
Sources: [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29577586/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### What does Thermal Water do for dry skin?

Thermal water helps boost skin hydration and reduces dryness and stinging while calming the skin. It may also improve overall skin comfort and support your usual routine by keeping the skin calm.
Sources: [The Medical Journal of Malaysia, 2024](https://pubmed.ncbi.nlm.nih.gov/38553920/)

### Where does this serum go in a skincare routine for dry skin?

This serum goes in the evening routine after cleansing and before moisturizing, which keeps the routine simple and protects the skin around sun exposure. Using it at night helps lock in hydration and repair dry skin.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying it before your retinol to help keep your dry skin soft and smooth. Using a barrier-supporting moisturizer alongside retinol helps reduce dryness and irritation.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### How often should I use this serum?

You can use this moisturizing treatment in your evening routine for simplicity and extra safety around sun exposure. Daily application helps boost hydration and keeps dry skin soft and smooth.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this serum clog pores, cause breakouts or purging for dry skin?

This serum is unlikely to clog pores or cause breakouts for dry skin. Its hydrating ingredients help keep skin smooth without heavy oils that typically block pores.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this serum around the eyes or on my body?

You can use this serum around the eyes and on your body because its gentle formula helps hydrate and protect dry skin without causing irritation. Panthenol and glycerin provide deep moisturization and barrier repair, while dimethicone supports smoothness across different skin areas.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Is this serum fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (alcohol denat).

## Alternatives for dry skin

- [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/uk/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/dry-skin) — High fit — £34.00 at Amazon
- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/uk/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/dry-skin) — High fit — £18.40 at Amazon
- [Kiehl's Midnight Recovery Concentrate](https://lovi.care/skincare/uk/p/kiehl-s/midnight-recovery-concentrate/for/dry-skin) — Average fit — £52.50 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/uk/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — £8.29 at Amazon
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/uk/p/dear-klairs/supple-preparation-unscented-toner/for/dry-skin) — Superior fit — £11.49 at Amazon
- SPF: [Torriden DIVE-IN Mild Sunscreen](https://lovi.care/skincare/uk/p/torriden/dive-in-mild-sunscreen/for/dry-skin) — Superior fit — £22.00 at Amazon

## Where to buy

- Amazon.co.uk: £28.74 (https://www.amazon.co.uk/dp/B0C5RTTF6Q?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- Notino: £33.50 (https://www.notino.co.uk/la-roche-posay/cicaplast-b5-regenerative-serum-for-everyday-use/p-16203220/)
- Lookfantastic: £33.60 (https://www.lookfantastic.com/p/la-roche-posay-cicaplast-b5-face-serum-for-dehydrated-skin-30ml/14239221/)
Prices checked 17 Oct – 6 Nov 2026.

## Ingredients

Water, Panthenol, Glycerin, Alcohol Denat, Dimethicone, Hydroxyethylpiperazine Ethane Sulfonic Acid, Peg-20 Methyl Glucose Sesquistearate, Sodium Hyaluronate, Ammonium Polyacryloyldimethyl Taurate, Caprylyl Glycol, Vitreoscilla Ferment, Citric Acid, Xanthan Gum, Octyldodecanol, Tocopherol, Phenoxyethanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/la-roche-posay/cicaplast-b5-serum/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/la-roche-posay/cicaplast-b5-serum/for/dry-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/la-roche-posay/cicaplast-b5-serum/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/la-roche-posay/cicaplast-b5-serum/for/dry-skin
- France: https://lovi.care/skincare/fr/p/la-roche-posay/cicaplast-b5-serum/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/la-roche-posay/cicaplast-b5-serum/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/la-roche-posay/cicaplast-b5-serum/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/la-roche-posay/cicaplast-b5-serum/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/la-roche-posay/cicaplast-b5-serum/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/la-roche-posay/cicaplast-b5-serum/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/la-roche-posay/cicaplast-b5-serum/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/la-roche-posay/cicaplast-b5-serum/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/la-roche-posay/cicaplast-b5-serum/for/dry-skin