Kate Somerville Kx Active Concentrates Bio-Mimicking Peptides Serum for mature skin

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Questions and answers

What the research says

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment.

  American Journal of Clinical Dermatology, 2002

• A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability.

  The Journal of Dermatological Treatment, 2017

• A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment.

  Journal of Cosmetic Dermatology, 2025

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Mangifera indica extract-loaded green nanolipid carriers in topical emulsion amplified overall antioxidant effectiveness and antiaging activity compared to vehicle in human volunteers over three months.

  Biomedicines, 2022

• Mangifera indica extract reduced lipid production by 40% in sebocytes, improved sebum quality and quantity in Caucasian volunteers, reduced porphyrins expression, and decreased C. acnes lipase activity by 29% compared to placebo while protecting microbiota equilibrium.

  Molecules, 2022

• Mango butter-based foot care cream repaired worn and cracked skin in all human volunteers and exhibited a significant healing response in rat excision and incision wound models compared to untreated conditions.

  Indian Journal of Pharmaceutical Sciences, 2008

Ingredients

Water, Ppg-24-Glycereth-24, Glycerin, Propanediol, Spondias Mombin Extract Pulp, Mangifera Indica Extract Pulp, Musa Sapientum Extract Pulp, Acetyl Glutamine, Sodium Hyaluronate, Acer Rubrum Extract, Sh-Polypeptide-1, Sh-Oligopeptide-2, Sh-Oligopeptide-1, Sh-Polypeptide-9, Sh-Polypeptide-11, Panthenol, Cichorium Intybus Leaf Extract, Zinc Pca, Caprylyl Glycol, Glycine Soja Seed Extract Soybean Seed Extract, Lecithin, Sclerotium Gum, Pullulan, 1,2-Hexanediol, Bacillus Folic Acid Extract Ferment, Caprylhydroxamic Acid, Silica, Adenosine, Benzyl Alcohol, Potassium Sorbate, Capryl Glycol, Butylene Glycol, Hexylene Glycol, Disodium Edta, Citric Acid, Sodium Benzoate, Xanthan Gum

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.