# iS Clinical Brightening Serum for dry skin

**Lovi Fit: Low fit for dry skin.**
Dry Skin Fit: Average · Effectiveness: Average · Safety: Concerning.

Page: https://lovi.care/skincare/uk/p/is-clinical/brightening-serum/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [iS Clinical](https://lovi.care/skincare/uk/brands/is-clinical)
Category: [Serums and treatments](https://lovi.care/skincare/uk/best/serums)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A weak match for dry skin; the serums alongside fit it better.

## Why this fit

- Offers moderate brightening for your dry skin due to alpha-arbutin and saccharum officinarum extract, which help to even skin tone and provide mild resurfacing benefits. Glycerin offers humectant action, but the formula lacks sufficient emollient or occlusive ingredients to fully address dryness.
- The presence of Alcohol Denat and Menthol carries some risk of irritation for your dry skin.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/is-clinical/brightening-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/uk/p/is-clinical/brightening-serum/for/dry-skin): Low (this page)
- [Combination skin](https://lovi.care/skincare/uk/p/is-clinical/brightening-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/uk/p/is-clinical/brightening-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/uk/p/is-clinical/brightening-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/uk/p/is-clinical/brightening-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/uk/p/is-clinical/brightening-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/is-clinical/brightening-serum/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/is-clinical/brightening-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Alpha-Arbutin, Ascophyllum Nodosum Extract, Vaccinium Myrtillus Leaf Extract Fruit, Willow Bark Extract, Saccharum Officinarum Extract

## What the research says

- Encapsulation of alpha arbutin in an optimized ethosomal gel significantly improved skin melanin reduction, moisture content, and elasticity in human volunteers compared to conventional formulations. ([Heliyon, 2023](https://pubmed.ncbi.nlm.nih.gov/37681127/))
- Topical 30% l-menthol decreased cold pain thresholds and enhanced pain responses to suprathreshold noxious cold stimuli without affecting other stimuli in 39 healthy subjects compared to ethanol control. ([Pain, 2006](https://pubmed.ncbi.nlm.nih.gov/16527405/))
- Topical high-concentration L-menthol consistently induces cold pain threshold elevation and increased supra-threshold cold pain sensitivity in healthy volunteers, and successfully establishes cold allodynia or hyperalgesia in animals, serving as a predictable surrogate model. ([European Journal of Pain, 2014](https://pubmed.ncbi.nlm.nih.gov/23963768/))
- A non-hydroquinone topical formulation (SKNB19) improved hyperpigmentation by 28.5% in patient self-assessment and 27% in independent reviewer assessment compared with 4% hydroquinone in 18 adult subjects, while showing significantly less irritation and better tolerability. ([Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/33022197/))
- Combining a home-based radiofrequency device and arbutin cream reduced mMASI scores by 25.6% and melanin index by 22.8% at 8 weeks compared to baseline in 38 participants. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/39918262/))
- Polyvinyl pyrrolidone-K90/Eudragit RL100 dissolving microneedle patches loaded with alpha-arbutin and resveratrol enhanced intradermal delivery by approximately 2.6 times compared to cream and slightly decreased the melanin index in human participants without causing skin irritation. ([Biomaterials Science, 2023](https://pubmed.ncbi.nlm.nih.gov/37183632/))
- Fermented bilberry extract improved wrinkle depth, skin smoothness, roughness, firmness, elasticity, antioxidant capacity, and complexion evenness compared to a placebo in 66 subjects over 84 days. ([Nutrients, 2024](https://pubmed.ncbi.nlm.nih.gov/39064646/))
- Topical application of oil-in-water creams containing wild bilberry leaves extract and seeds oil produced significant beneficial effects on the skin of healthy human volunteers. ([Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/33809607/))
- Bilberry fruit extract incorporated into chitosan-based hydrogels demonstrated antioxidant, anti-hyaluronidase, and anti-tyrosinase activities, supporting their potential use in topical anti-aging preparations. ([Antioxidants, 2024](https://pubmed.ncbi.nlm.nih.gov/38247529/))
- A botanical face cleanser with hops and willow bark extract continuously reduced skin sebum levels without reactive seborrhea after treatment in 21 healthy volunteers compared to a sodium laureth sulfate cleanser, with neither cleanser causing skin irritation. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30022595/))
- Bioactive lipid nanocarriers co-loaded with willow bark or ivy leaf extracts and UV-filters provided pronounced UVA photoprotection up to an SPF-equivalent value of 13 and a maximum in vivo skin hydration effect of 97% when prepared with pomegranate oil. ([Nanomaterials, 2022](https://pubmed.ncbi.nlm.nih.gov/35889587/))
- A topical serum containing 0.5% salicin applied twice daily reduced visible signs of skin aging, including wrinkles and tactile roughness, in 30 female subjects over 12 weeks compared to baseline. ([Journal of Cosmetic Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20883292/))
- Repeated short-contact 70% glycolic acid peels provided superior results in atrophic acne scars compared to daily low-strength glycolic acid cream or placebo in 58 women over 24 weeks. ([International Journal of Dermatology, 2000](https://pubmed.ncbi.nlm.nih.gov/11095203/))

## Why other serums fit dry skin better

- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))

## What reviewers say

This review data is based on limited data. Users frequently report visible improvements in dark spots, skin radiance, and overall texture, noting that the formula is generally gentle enough for various skin types, including sensitive skin. Some users may find it less effective for stubborn conditions or notice potential irritation if used too frequently.

- Liked: Fades dark spots (mostly mentioned)
- Liked: Evens skin tone (often mentioned)
- Liked: Gentle formula (sometimes noted)
- Liked: Improves texture (sometimes noted)
- Disliked: Slow/no results (sometimes noted)
- Disliked: Potential breakouts (rarely noted)
- Disliked: Price point (rarely noted)
- Disliked: Tingling sensation (rarely noted)

## How to apply

- Apply this serum PM, starting 3×/week and working up to daily use as your skin adjusts.
- Place the serum after cleansing and toner, but right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on slightly damp skin to help lock in extra moisture.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### Why is iS Clinical Brightening Serum a weak match for dry skin?

This serum is a weak match because it lacks enough softening and sealing ingredients to fully address dry skin, and alcohol denat and menthol may irritate it. A product of this type needs soothing ingredients that provide significant hydration and support skin barrier health without any risk of irritation.
Sources: [Pain, 2006](https://pubmed.ncbi.nlm.nih.gov/16527405/)

### Which ingredients make this serum a poor fit for dry skin?

Alcohol Denat and Menthol make this serum a poor fit for dry skin because they carry a risk of irritation, and the formula lacks enough heavy softening or sealing ingredients to fully handle dryness. A treatment for dry skin needs rich, soothing hydrators, skin barrier protectors like ceramides or niacinamide, and nourishing extras like propolis, peptides, or beneficial ferments without any irritating ingredients.
Sources: [Pain, 2006](https://pubmed.ncbi.nlm.nih.gov/16527405/)

### What does Alpha-Arbutin do for dry skin?

Alpha-arbutin is not primarily designed to hydrate dry skin, but advanced formulations containing it may help improve moisture content and elasticity while brightening dark spots. A dry skin type needs rich moisturizers with ingredients like ceramides, hyaluronic acid, and facial oils to properly nourish the skin barrier.
Sources: [Heliyon, 2023](https://pubmed.ncbi.nlm.nih.gov/37681127/)

### What does Ascophyllum Nodosum Extract do for dry skin?

Ascophyllum Nodosum Extract is unlikely to provide meaningful sun protection on its own for dry skin. Skincare for dry skin needs rich, nourishing ingredients like natural oils and heavy moisturizers to keep skin soft and smooth.
Sources: [Marine Drugs, 2022](https://pubmed.ncbi.nlm.nih.gov/36355010/)

### Where does this serum go in a skincare routine for dry skin?

This serum goes in the evening routine after cleansing and before moisturizing. Because this product is a weak match for dry skin and lacks enough rich softening ingredients to fully address dryness while containing ingredients that may cause irritation, dry skin needs treatments that include extra hydrating and soothing ingredients.

### Can I use this serum with retinol, and in what order?

Using this serum with retinol is unlikely to be comfortable for dry skin, because the formula lacks rich softening ingredients and contains drying alcohols that may trigger irritation. To use them anyway, apply your gentle retinol product first, wait for it to absorb, and follow with a deeply nourishing moisturizer to protect your skin barrier.

### How often should I use this serum?

You can use this serum in the evening once a week to start, as it is a weak match for your dry skin and carries some risk of irritation from alcohol and menthol. If your skin tolerates it well and stays calm, you may carefully use it more often. A product for this skin type needs rich moisturizing oils and butters to lock in hydration and prevent dryness.

### Can this serum clog pores, cause breakouts or purging for dry skin?

This serum is unlikely to clog pores or cause breakouts for dry skin, though reviewer feedback shows a low risk of potential breakouts. Because it lacks rich smoothing or sealing ingredients to lock in moisture, dry skin needs creams or oils with rich, sealing ingredients that soften and protect dry skin.

### Is this serum fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (alcohol denat).

## Alternatives for dry skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/uk/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/dry-skin) — Superior fit — £36.96 at Amazon
- [KraveBeauty Great Barrier Relief](https://lovi.care/skincare/uk/p/kravebeauty/great-barrier-relief/for/dry-skin) — Superior fit — £32.95 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/uk/p/augustinus-bader/the-serum/for/dry-skin) — Superior fit — £248.00 at Amazon

## Routine for dry skin

### AM

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/uk/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — £8.29 at Amazon
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/uk/p/dear-klairs/supple-preparation-unscented-toner/for/dry-skin) — Superior fit — £11.49 at Amazon
- Moisturizer: [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/uk/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/dry-skin) — Superior fit — £14.74 at Amazon
- SPF: [Torriden DIVE-IN Mild Sunscreen](https://lovi.care/skincare/uk/p/torriden/dive-in-mild-sunscreen/for/dry-skin) — Superior fit — £22.00 at Amazon

### PM

- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/uk/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — £13.58 at Amazon
- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/uk/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — £8.29 at Amazon
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/uk/p/peach-and-lily/glass-skin-refining-serum/for/dry-skin) — Superior fit — £59.74 at Amazon
- Moisturizer: [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/uk/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/dry-skin) — Superior fit — £14.74 at Amazon

### Weekly

- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/uk/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — £13.58 at Amazon
- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/uk/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — £8.29 at Amazon
- Nourishing Mask: [MEDIHEAL Vita Essential Mask](https://lovi.care/skincare/uk/p/mediheal/vita-essential-mask/for/dry-skin) — Superior fit — £17.00 at Amazon
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/uk/p/peach-and-lily/glass-skin-refining-serum/for/dry-skin) — Superior fit — £59.74 at Amazon
- Moisturizer: [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/uk/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/dry-skin) — Superior fit — £14.74 at Amazon

## Where to buy

No store in United Kingdom has a checked price for this product, so the page shows none.

## Ingredients

Butylene Glycol, Water, Glycerin, Alcohol Denat, Ascophyllum Nodosum Extract, Saccharum Officinarum Extract, Vaccinium Myrtillus Leaf Extract Fruit, Alpha-Arbutin, Glyceryl Polyacrylate, Polyporus Umbellatus Extract Mushroom Extract, Willow Bark Extract, Menthol, Phenoxyethanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/is-clinical/brightening-serum/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/is-clinical/brightening-serum/for/dry-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/is-clinical/brightening-serum/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/is-clinical/brightening-serum/for/dry-skin
- France: https://lovi.care/skincare/fr/p/is-clinical/brightening-serum/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/is-clinical/brightening-serum/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/is-clinical/brightening-serum/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/is-clinical/brightening-serum/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/is-clinical/brightening-serum/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/is-clinical/brightening-serum/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/is-clinical/brightening-serum/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/is-clinical/brightening-serum/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/is-clinical/brightening-serum/for/dry-skin