# Good Molecules Niacinamide Serum for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: Superior · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/uk/p/good-molecules/niacinamide-serum/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [Good Molecules](https://lovi.care/skincare/uk/brands/good-molecules)
Category: [Serums and treatments](https://lovi.care/skincare/uk/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other serums fit it better.

## Why this fit

- Offers moderate benefits for your combination skin, as niacinamide helps regulate sebum production to address oily shine and glycerin provides essential hydration. This formulation is well-suited for your skin type and main goal.
- The inclusion of niacinamide in moderate concentrations aids in evening skin tone and decongesting pores, providing relevant skincare benefits.
- The product is safe for your combination skin, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/good-molecules/niacinamide-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/uk/p/good-molecules/niacinamide-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/uk/p/good-molecules/niacinamide-serum/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/uk/p/good-molecules/niacinamide-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/uk/p/good-molecules/niacinamide-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/uk/p/good-molecules/niacinamide-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/uk/p/good-molecules/niacinamide-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/good-molecules/niacinamide-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/good-molecules/niacinamide-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Niacinamide, Glycerin, Dipropylene Glycol, Betaine, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- Soaps containing betaine caused the least skin irritation compared to other tested soaps in twenty-eight healthy subjects, though irritation did not decrease with increasing concentrations of betaine. ([Skin Research and Technology, 2003](https://pubmed.ncbi.nlm.nih.gov/12535284/))
- A combination of Aloe barbadensis leaf extract and trimethylglycine in a 1:1 mass ratio synergistically increased aquaporin 3 expression by up to 380% in keratinocytes and safely improved skin hydration in healthy volunteers. ([Molecules, 2024](https://pubmed.ncbi.nlm.nih.gov/38611819/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical dry mouth products containing olive oil, betaine, and xylitol significantly increased unstimulated whole salivary flow rates, reduced xerostomia complaints, and improved quality of life in adults with polypharmacy-induced xerostomia compared to their normal routine care, with no clinically significant adverse events. ([Journal of Oral Rehabilitation, 2007](https://pubmed.ncbi.nlm.nih.gov/17824884/))
- Mixed surfactant systems of sodium dodecyl sulfate and dimethyl dodecyl amido betaine significantly reduce acute skin irritation potential in human volunteers compared with the individual surfactants, demonstrating that irritation potential cannot be predicted by simple summation. ([Food and Chemical Toxicology, 1998](https://pubmed.ncbi.nlm.nih.gov/9609395/))
- Polyhexanide/betaine may be nontoxic and effective in enhancing wound healing, whereas the majority of other topical cleaning agents are locally toxic and of limited or no proven efficacy. ([Advances in Skin & Wound Care, 2013](https://pubmed.ncbi.nlm.nih.gov/23507692/))

## What reviewers say

Based on a very large amount of data, this serum is highly regarded for its lightweight, non-sticky feel and its effectiveness in visibly reducing pores and smoothing skin texture, all at an accessible price. Many users found it beneficial for controlling oil and redness. A smaller number of users reported experiencing breakouts or irritation, indicating it might not be suitable for all sensitive skin types.

- Liked: Affordable price (mostly mentioned)
- Liked: Improves texture (often mentioned)
- Liked: Minimizes pores (often mentioned)
- Liked: Controls oil/redness (sometimes noted)
- Liked: Elegant texture (sometimes noted)
- Disliked: Caused breakouts (sometimes noted)
- Disliked: No visible results (rarely noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Skin irritation (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Good Molecules Niacinamide Serum work for combination skin?

Good Molecules Niacinamide Serum works moderately well for combination skin, as niacinamide helps control oily shine while glycerin provides essential hydration. To fit this skin type even better, a treatment of this type needs effective ingredients like propolis or zinc PCA that deliver optimal balance and hydration without feeling heavy.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for combination skin?

Niacinamide and glycerin make this serum a good fit for your combination skin because they help control oily shine and provide essential hydration. To fit this skin type even better, a treatment of this type needs effective ingredients like propolis or zinc PCA to boost radiance and manage oil without causing irritation.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Niacinamide do for combination skin?

Niacinamide helps balance oily areas by reducing excess shine and pore size while keeping dry patches hydrated and smooth. It also works to calm redness and even out skin tone, making it very suitable for combination skin.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### What does Glycerin do for combination skin?

Glycerin helps keep combination skin soft and smooth by pulling moisture in and keeping it there. It improves hydration and supports your skin barrier, which is unlikely to cause irritation.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Where does this serum go in a skincare routine for combination skin?

This treatment goes in the evening routine after cleansing and before moisturizing, though some serums can also be used in the morning or twice a day. To better fit combination skin, products of this type need ingredients that balance oil production while keeping dry areas hydrated.

### Can I use this serum with retinol, and in what order?

Yes, you can use this serum with retinol by applying the niacinamide serum first to help soothe your skin before putting on your retinol. This combination is generally safe and unlikely to cause irritation.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use this serum?

You can use this serum in your evening routine. A product of this type for your combination skin needs ingredients like niacinamide and glycerin to help balance oily shine and provide essential hydration.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can this serum clog pores, cause breakouts or purging for combination skin?

This serum is unlikely to cause irritation for your combination skin, but some reviewers do mention that it can cause breakouts. Combination skin types that are prone to clogged pores need lightweight, balancing ingredients like niacinamide and soothing hydrators that keep skin clear without heavy oils.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/uk/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/combination-skin) — Superior fit — £36.96 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/uk/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin) — Superior fit — £24.20 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/uk/p/augustinus-bader/the-serum/for/combination-skin) — Superior fit — £248.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/uk/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — £14.99 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/uk/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — £30.37 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/uk/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — £14.80 at Amazon

## Where to buy

- Amazon.co.uk: £6.00 (https://www.amazon.co.uk/dp/B08R994Q1L?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Niacinamide, Dipropylene Glycol, Glycerin, 1,2-Hexanediol, Betaine, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Xanthan Gum, Ethylhexylglycerin, Polysorbate 60, Sorbitan Isostearate, Diphenyl Dimethicone, Disodium Edta, Triethylhexanoin, Polyglyceryl-10 Oleate, Hydrogenated Lecithin, Phenoxyethanol, Chlorphenesin, Caprylyl Glycol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/good-molecules/niacinamide-serum/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/good-molecules/niacinamide-serum/for/combination-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/good-molecules/niacinamide-serum/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/good-molecules/niacinamide-serum/for/combination-skin
- France: https://lovi.care/skincare/fr/p/good-molecules/niacinamide-serum/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/good-molecules/niacinamide-serum/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/good-molecules/niacinamide-serum/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/good-molecules/niacinamide-serum/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/good-molecules/niacinamide-serum/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/good-molecules/niacinamide-serum/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/good-molecules/niacinamide-serum/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/good-molecules/niacinamide-serum/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/good-molecules/niacinamide-serum/for/combination-skin