# Dermisa Skin Fade Cream for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: Average · Effectiveness: Average · Safety: Low Risk.

Page: https://lovi.care/skincare/uk/p/dermisa/skin-fade-cream/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [Dermisa](https://lovi.care/skincare/uk/brands/dermisa)
Category: [Serums and treatments](https://lovi.care/skincare/uk/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other serums fit it better.

## Why this fit

- Offers moderate skin brightening for your combination skin due to hydroquinone and Phyllanthus Emblica Fruit Extract, which help to even skin tone, while niacinamide provides some seboregulation and hydration.
- The formula provides general skincare benefits and hydration, but lacks specialized ingredients to effectively target the oily shine characteristic of your combination skin.
- The product is generally safe for your combination skin, though the presence of ethanol and ascorbic acid may pose a slight risk of irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/dermisa/skin-fade-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/uk/p/dermisa/skin-fade-cream/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/uk/p/dermisa/skin-fade-cream/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/uk/p/dermisa/skin-fade-cream/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/uk/p/dermisa/skin-fade-cream/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/uk/p/dermisa/skin-fade-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/uk/p/dermisa/skin-fade-cream/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/dermisa/skin-fade-cream/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/dermisa/skin-fade-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Ascorbic Acid, Hydroquinone, Niacinamide, Licorice Root Extract, Phyllanthus Emblica Fruit Extract

## What the research says

- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- Topical application of a 0.1% amla branch extract gel demonstrated superior anti-skin aging efficacy, including skin lightening, enhanced elasticity and hydration, and wrinkle reduction in 20 volunteers compared to a placebo over 84 days. ([Journal of Traditional and Complementary Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34522633/))
- Ethanol enhances skin lipid bilayer permeability through the dual actions of lipid extraction and increasing lipid chain mobility, driven by its superior ability to form hydrogen bonds with lipid headgroups. ([RSC Advances, 2020](https://pubmed.ncbi.nlm.nih.gov/35497613/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- TFC-1067 and 2% hydroquinone both significantly lightened facial dyschromia after 8 and 12 weeks in 48 healthy female subjects, but only hydroquinone also lightened normal skin. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/33098161/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Combining 755 nm alexandrite laser with topical licorice gel significantly reduces terminal hair counts compared to alexandrite laser with placebo in women with idiopathic hirsutism. ([Evidence-based Complementary and Alternative Medicine, 2015](https://pubmed.ncbi.nlm.nih.gov/26273313/))
- Licochalcone A activated Nrf2 signaling, elevated cytoprotective enzymes, increased the reduced-to-oxidized glutathione ratio, and decreased reactive oxygen species in human fibroblasts and neutrophils, while a LicA-rich licorice extract lowered UVA-induced oxidative processes in vivo. ([Experimental Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25381913/))
- Bioactive glycyrrhizic acid and oxymatrine ionic liquid self-assembled nanomicelles significantly promoted the transdermal permeation, subcutaneous retention, and anti-photoaging efficacy of palmitoyl pentapeptide-4 in cellular and animal models compared to unformulated peptide. ([Advanced Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39783908/))
- Topical application of Emblica officinalis accelerates dermal wound contraction and closure, and increases cellular proliferation, collagen cross-linking, and antioxidant activity in rats. ([Wound Repair and Regeneration, 2009](https://pubmed.ncbi.nlm.nih.gov/19152656/))
- PVP/CS/Phyllanthus emblica nanofiber dry facial masks containing 29.0% Phyllanthus emblica achieve a tyrosinase inhibition rate of 99.53%, complete agent release in twenty minutes, cell activity of at least 82.60%, and confine inflammatory factors. ([Polymers, 2022](https://pubmed.ncbi.nlm.nih.gov/36365465/))

## Why other serums fit combination skin better

- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))
- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))

## What reviewers say

Users report mixed results with this skin fade cream, with many appreciating its lightweight, non-greasy texture and suitability for various skin types. However, a significant number of users note that results for hyperpigmentation, acne scars, and sunspots are often subtle or require long-term, consistent use to become visible.

- Liked: Lightweight, non-greasy texture (often mentioned)
- Disliked: Slow or minimal results (often mentioned)
- Liked: Gentle on skin (sometimes noted)
- Liked: Good under makeup (sometimes noted)
- Liked: Improves skin tone (sometimes noted)
- Disliked: Not for severe spots (sometimes noted)
- Disliked: Potential for breakouts (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Dermisa Skin Fade Cream work for combination skin?

Dermisa Skin Fade Cream is an average fit for combination skin, offering moderate evening of skin tone while carrying a slight risk of irritation from ethanol and ascorbic acid. A treatment for this skin needs ingredients like niacinamide, propolis, or zinc PCA that regulate oiliness and provide hydration without any risk of irritation.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Journal of Traditional and Complementary Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34522633/)

### Which ingredients make this cream a good fit for combination skin?

Hydroquinone and Phyllanthus Emblica Fruit Extract help to even your skin tone, while niacinamide provides some oil control and hydration for your combination skin. However, this product needs ingredients like propolis or zinc PCA to effectively target oily shine and keep your skin balanced without irritation.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Journal of Traditional and Complementary Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34522633/)

### What does Vitamin C do for combination skin?

Vitamin C helps brighten dull areas and smooth out uneven texture on combination skin while protecting against daily environmental stress. It may also help keep pores clear and skin firm by supporting collagen production, though drier spots may need an added moisturizer to stay comfortable.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/), [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37128827/)

### What does Hydroquinone do for combination skin?

Hydroquinone is a strong skin-lightening ingredient that helps fade stubborn dark spots and uneven patches on combination skin. It works to reduce excess pigment, though products of this type for combination skin also need gentle, balancing ingredients to keep dry areas smooth and oily zones calm without causing irritation.
Sources: [Indian Journal of Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23716817/)

### Where does this cream go in a skincare routine for combination skin?

This cream goes in the evening routine as a treatment step after cleansing and toning. It helps even skin tone, but this skin type also needs ingredients that manage oily shine.

### Can I use it with retinol, and in what order?

This treatment can be used alongside retinol by applying it in your evening routine, but use caution since combining it with ingredients like ascorbic acid and ethanol may cause irritation. To properly care for combination skin, a product of this type needs balancing ingredients that control excess oil and shine.

### How often should I use this cream?

This treatment works for your combination skin in the evening, though other products fit it better. A product of this type needs mattifying and oil-controlling ingredients like salicylic acid or zinc to effectively target oily shine.

### Can it clog pores, cause breakouts or purging for combination skin?

This cream is unlikely to cause breakouts for combination skin, as reviewers report this risk as low. However, because it lacks specialized ingredients to control oily shine, combination skin needs oil-balancing ingredients and lightweight hydrators to properly manage oil and prevent clogged pores.

### Is this cream fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (ethanol).

## Alternatives for combination skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/uk/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/combination-skin) — Superior fit — £36.96 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/uk/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin) — Superior fit — £24.20 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/uk/p/augustinus-bader/the-serum/for/combination-skin) — Superior fit — £248.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/uk/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — £14.99 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/uk/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — £30.37 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/uk/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — £14.80 at Amazon

## Where to buy

No store in United Kingdom has a checked price for this product, so the page shows none.

## Ingredients

Water, Glyceryl Stearate, Peg-100 Stearate, Niacinamide, Caprylic Capric Triglyceride, Propylene Glycol, Stearic Acid, Cetyl Alcohol, Stearyl Stearate, Ethylhexyl Methoxycinnamate, Phenoxyethanol, Benzoic Acid, Ethylhexylglycerin, Glycereth-2 Cocoate, Phyllanthus Emblica Fruit Extract, Ethanol, Dimethicone, Xanthan Gum, Sorbic Acid, Ascorbic Acid, Tocopheryl Acetate, Aminomethyl Propanol, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Hydroquinone, Octyl Dimethyl Paba
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/dermisa/skin-fade-cream/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/dermisa/skin-fade-cream/for/combination-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/dermisa/skin-fade-cream/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/dermisa/skin-fade-cream/for/combination-skin
- France: https://lovi.care/skincare/fr/p/dermisa/skin-fade-cream/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/dermisa/skin-fade-cream/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/dermisa/skin-fade-cream/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/dermisa/skin-fade-cream/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/dermisa/skin-fade-cream/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/dermisa/skin-fade-cream/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/dermisa/skin-fade-cream/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/dermisa/skin-fade-cream/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/dermisa/skin-fade-cream/for/combination-skin