# Clean & Clear Persa-Gel 10 for mature skin

**Lovi Fit: Low fit for mature skin.**
Normal Skin Fit: Average · Effectiveness: High · Safety: Concerning.

Page: https://lovi.care/skincare/uk/p/clean-and-clear/persa-gel-10/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [Clean & Clear](https://lovi.care/skincare/uk/brands/clean-and-clear)
Category: [Serums and treatments](https://lovi.care/skincare/uk/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A weak match for mature skin; the serums alongside fit it better.

## Why this fit

- Offers moderate treatment for acne-prone skin due to the presence of benzoyl peroxide, which reduces acne lesions and provides keratolytic action for normal skin, but it lacks sufficient hydrating and emollient ingredients for optimal results.
- While benzoyl peroxide is effective for acne, it is not specialized for anti-aging concerns, which is your main goal.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/clean-and-clear/persa-gel-10/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/uk/p/clean-and-clear/persa-gel-10/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/uk/p/clean-and-clear/persa-gel-10/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/uk/p/clean-and-clear/persa-gel-10/for/sensitive-skin): Low
- [Acne-prone skin](https://lovi.care/skincare/uk/p/clean-and-clear/persa-gel-10/for/acne-prone-skin): Superior
- [Skin with dark spots](https://lovi.care/skincare/uk/p/clean-and-clear/persa-gel-10/for/dark-spots): Low
- [Mature skin](https://lovi.care/skincare/uk/p/clean-and-clear/persa-gel-10/for/mature-skin): Low (this page)
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/clean-and-clear/persa-gel-10/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/clean-and-clear/persa-gel-10/for/oily-acne-prone-skin): Superior

## Key ingredients

Benzoyl Peroxide, Carbomer Homopolymer Type B, Hydroxypropyl Methylcellulose, Sodium Hydroxide

## What the research says

- Topical benzoyl peroxide may improve acne more effectively than placebo or no treatment, while showing little to no difference compared with adapalene or clindamycin, but with an increased risk of treatment discontinuation due to adverse effects compared to placebo. ([The Cochrane Database of Systematic Reviews, 2020](https://pubmed.ncbi.nlm.nih.gov/32175593/))
- Once-daily fixed-dose clindamycin phosphate 1.2%/benzoyl peroxide 3.1%/adapalene 0.15% gel achieved superior treatment success (52.5%) and greater reductions in inflammatory and noninflammatory lesions compared to vehicle (8.1%) and dyad component gels in participants with moderate-to-severe acne over 12 weeks. ([American Journal of Clinical Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34674160/))
- Preoperative treatment with benzoyl peroxide significantly decreases the bacterial skin load of Cutibacterium acnes in patients undergoing elective shoulder surgery from skin incision until wound closure compared to preparation with soap. ([Journal of Shoulder and Elbow Surgery, 2021](https://pubmed.ncbi.nlm.nih.gov/33545336/))
- Twice daily application of a multitargeted dermocosmetic cream provided comparable efficacy to benzoyl peroxide 5% gel in reducing inflammatory, non-inflammatory, and total lesions in 150 Caucasian subjects with mild-to-moderate acne over 56 days, while demonstrating superior skin tolerability. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/))
- Topical clindamycin phosphate 1.2%/adapalene 0.15%/benzoyl peroxide 3.1% gel achieved significantly greater treatment success and lesion reductions compared to vehicle in participants with moderate-to-severe acne. ([Journal of the American Academy of Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37656094/))
- Daily application of adapalene 0.3%/benzoyl peroxide 2.5% gel reduced and prevented atrophic acne scar formation, achieving a total scar count change of -15.5% versus +14.4% for vehicle over 24 weeks in 67 subjects with moderate or severe facial acne. ([American Journal of Clinical Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29549588/))
- Topical chloramphenicol-betamethasone combined with sodium hyaluronate/trehalose/carbomer gel compared to chloramphenicol-betamethasone alone reduced most subjective symptoms at 1 week but increased blurred vision at 4 weeks following strabismus surgery in 31 patients, with no significant differences in conjunctival inflammation between treatments. ([Journal of Ocular Pharmacology and Therapeutics, 2019](https://pubmed.ncbi.nlm.nih.gov/31298607/))
- Incorporating nanoemulsions into hydrogels with increasing Carbopol 934 proportions from 1% to 3% progressively decreased the percutaneous flux rates of terbinafine and citral, increased drug accumulation in the stratum corneum while decreasing it in the epidermis/dermis compared to nanoemulsions alone, and shifted delivery routes from skin appendages to intercellular paths. ([International Journal of Nanomedicine, 2016](https://pubmed.ncbi.nlm.nih.gov/27877042/))
- Topical liquiritin carbomer gel treatment restored skin barrier function, increased barrier proteins and antioxidant enzymes, and decreased inflammatory cytokines and oxidative stress in a mouse model of glucocorticoid-induced skin inflammation. ([Pharmaceutics, 2024](https://pubmed.ncbi.nlm.nih.gov/39204346/))
- Biodegradable wound dressings functionalized with silver nanoparticles showed >99% pathogen growth inhibition, bactericidal effects, free radical scavenging, reduced inflammatory response in macrophages, and accelerated wound healing in animals. ([International Journal of Biological Macromolecules, 2022](https://pubmed.ncbi.nlm.nih.gov/35780920/))
- Hydroxypropyl methylcellulose hydrogel formulations of berberine chloride-loaded escinosomes increased skin residence time and transdermal permeability while maintaining high safety and biocompatibility without skin irritation. ([International Journal of Biological Macromolecules, 2020](https://pubmed.ncbi.nlm.nih.gov/32682035/))

## Why other serums fit mature skin better

- Topical application of retinol and retinoic acid both increased epidermal thickness and upregulated collagen genes and proteins in human skin, with retinol producing similar histological and molecular changes to retinoic acid alongside a significant reduction in facial wrinkles after 12 weeks. ([Journal of Cosmetic Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/26578346/))
- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))

## What reviewers say

Based on a very large amount of data, users consistently praise this maximum-strength benzoyl peroxide gel as a highly effective and affordable spot treatment for stubborn acne and cystic bumps. Because of its potency, it frequently causes significant dryness and peeling, making it best suited for oily skin types or targeted application rather than all-over use.

- Liked: Affordable price (mostly mentioned)
- Disliked: Excessive drying (mostly mentioned)
- Liked: Clears pimples (often mentioned)
- Liked: Effective spot treatment (often mentioned)
- Disliked: Bleaches fabrics (often mentioned)
- Disliked: Causes burning (sometimes noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### Why is Clean & Clear Persa-Gel 10 treatment a weak match for mature skin?

Clean & Clear Persa-Gel 10 is a weak match for mature skin because it targets acne with benzoyl peroxide rather than addressing anti-aging concerns like wrinkles and fine lines. Additionally, it lacks sufficient hydrating and softening ingredients to keep mature skin balanced and comfortable. A treatment for this skin needs high-quality anti-aging ingredients, potent antioxidants, hydrating components, nourishing oils, and peptides.

### Which ingredients make this treatment a poor fit for mature skin?

This treatment is a weak match for mature skin because it lacks sufficient hydrating and softening ingredients, and benzoyl peroxide does not target anti-aging concerns. A product of this type needs antioxidants, hydrating components, skin-repairing ingredients, nourishing oils, and peptides to properly address mature skin.

### What does Benzoyl Peroxide do for mature skin?

Benzoyl peroxide is unlikely to provide specific anti-aging benefits for mature skin and is primarily used to clear acne. Because it tends to dry the skin, mature skin needs a gentle, hydrating cleanser and a rich moisturizer containing ceramides to protect the skin barrier while treating breakouts.
Sources: [The Cochrane Database of Systematic Reviews, 2020](https://pubmed.ncbi.nlm.nih.gov/32175593/), [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37276158/)

### What does Water do for mature skin?

Water helps keep mature skin hydrated, which significantly lowers the severity of wrinkles and maintains elasticity. Because aging skin often loses moisture and firmness, it needs hydrating ingredients like glycerin and hyaluronic acid to stay plump and smooth.
Sources: [Skin Research and Technology, 2013](https://pubmed.ncbi.nlm.nih.gov/22672420/)

### Where does this treatment go in a skincare routine for mature skin?

This treatment goes in the evening routine before your moisturizer. It is a weak match for mature skin because it lacks the nourishing, hydrating, and anti-aging ingredients needed to keep this skin type soft and smooth.

### Can I use this treatment with retinol, and in what order?

This product is a weak match for mature skin because it focuses on clearing blemishes rather than targeting anti-aging concerns. A treatment of this type needs rich hydrating and softening ingredients to keep this skin soft and smooth.

### How often should I use this treatment?

This treatment is applied in the evening once a week to start, and can be used more often if your skin tolerates it well and sees good results. Because this product is a weak match for mature skin, a product of this type needs more hydrating and nourishing ingredients to keep mature skin soft and smooth.
Sources: [The Cochrane Database of Systematic Reviews, 2020](https://pubmed.ncbi.nlm.nih.gov/32175593/)

### Can this treatment clog pores, cause breakouts or purging for mature skin?

This treatment is unlikely to clog pores, but it may cause excessive drying and burning on mature skin. Because it lacks sufficient hydrating and softening ingredients, a product of this type needs added moisturizers and soothing agents to keep dry skin comfortable.
Sources: [The Cochrane Database of Systematic Reviews, 2020](https://pubmed.ncbi.nlm.nih.gov/32175593/)

### Is this treatment fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (benzyl alcohol).

## Alternatives for mature skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/uk/p/skinceuticals/c-e-ferulic/for/mature-skin) — Superior fit — £143.35 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/uk/p/neogen-dermalogy/real-vita-c-serum/for/mature-skin) — High fit — £25.95 at Amazon
- [La Mer The Regenerating Serum](https://lovi.care/skincare/uk/p/la-mer/the-regenerating-serum/for/mature-skin) — High fit — £372.06 at Amazon

## Routine for mature skin

### AM

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/uk/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — £14.99 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/uk/p/some-by-mi/snail-truecica-miracle-repair-toner/for/mature-skin) — Superior fit — £13.98 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/uk/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/mature-skin) — Superior fit — £38.50 at Amazon
- SPF: [Torriden DIVE-IN Mild Sunscreen](https://lovi.care/skincare/uk/p/torriden/dive-in-mild-sunscreen/for/mature-skin) — Superior fit — £22.00 at Amazon

### PM

- Pre-Cleanser: [Pyunkang Yul Deep Cleansing Oil](https://lovi.care/skincare/uk/p/pyunkang-yul/deep-cleansing-oil/for/mature-skin) — Superior fit — £23.92 at Amazon
- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/uk/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — £14.99 at Amazon
- Cleansing Toner: [First Aid Beauty Facial Radiance Pads](https://lovi.care/skincare/uk/p/first-aid-beauty/facial-radiance-pads/for/mature-skin) — Superior fit — £20.00 at Amazon
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/uk/p/peach-and-lily/glass-skin-refining-serum/for/mature-skin) — Superior fit — £59.74 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/uk/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/mature-skin) — Superior fit — £38.50 at Amazon

### Weekly

- Pre-Cleanser: [Pyunkang Yul Deep Cleansing Oil](https://lovi.care/skincare/uk/p/pyunkang-yul/deep-cleansing-oil/for/mature-skin) — Superior fit — £23.92 at Amazon
- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/uk/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — £14.99 at Amazon
- Enzyme Powder: [VT Cica Mild Powder Wash](https://lovi.care/skincare/uk/p/vt/cica-mild-powder-wash/for/mature-skin) — Superior fit — £9.55 at Amazon
- Nourishing Mask: [MEDIHEAL Vita Essential Mask](https://lovi.care/skincare/uk/p/mediheal/vita-essential-mask/for/mature-skin) — Superior fit — £17.00 at Amazon
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/uk/p/peach-and-lily/glass-skin-refining-serum/for/mature-skin) — Superior fit — £59.74 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/uk/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/mature-skin) — Superior fit — £38.50 at Amazon

## Where to buy

No store in United Kingdom has a checked price for this product, so the page shows none.

## Ingredients

Benzoyl Peroxide, Water, Carbomer Homopolymer Type B, Hydroxypropyl Methylcellulose, Sodium Hydroxide, Laureth-4, Disodium Edta, Benzyl Alcohol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/clean-and-clear/persa-gel-10/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/clean-and-clear/persa-gel-10/for/mature-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/clean-and-clear/persa-gel-10/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/clean-and-clear/persa-gel-10/for/mature-skin
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- Italy: https://lovi.care/skincare/it/p/clean-and-clear/persa-gel-10/for/mature-skin
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- Canada: https://lovi.care/skincare/ca/p/clean-and-clear/persa-gel-10/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/clean-and-clear/persa-gel-10/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/clean-and-clear/persa-gel-10/for/mature-skin
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- United Arab Emirates: https://lovi.care/skincare/ae/p/clean-and-clear/persa-gel-10/for/mature-skin