# Biossance 100% Squalane Oil for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: Average · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/uk/p/biossance/100-squalane-oil/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [Biossance](https://lovi.care/skincare/uk/brands/biossance)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other products fit it better.

## Why this fit

- Offers moderate moisturizing for your normal skin, as squalane provides emollient action to hydrate and smooth skin texture. This ingredient is well-suited for your skin type and offers general skincare benefits.
- While the product provides hydration, it lacks specialized ingredients to target your specific concerns of redness and irritation.
- The product is safe for your sensitive skin due to the absence of harsh ingredients and the inclusion of soothing squalane.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/biossance/100-squalane-oil/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/uk/p/biossance/100-squalane-oil/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/uk/p/biossance/100-squalane-oil/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/uk/p/biossance/100-squalane-oil/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/uk/p/biossance/100-squalane-oil/for/acne-prone-skin): Low
- [Skin with dark spots](https://lovi.care/skincare/uk/p/biossance/100-squalane-oil/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/uk/p/biossance/100-squalane-oil/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/biossance/100-squalane-oil/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/biossance/100-squalane-oil/for/oily-acne-prone-skin): Average

## Key ingredients

Squalane, Squalane Oil

## What the research says

- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))

## Why other products fit sensitive skin better

- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A dexpanthenol-containing cream accelerated skin barrier repair, increased stratum corneum hydration, reduced skin roughness, and decreased skin redness compared to vehicle and untreated controls in sodium lauryl sulphate-irritated skin. ([The Journal of Dermatological Treatment, 2002](https://pubmed.ncbi.nlm.nih.gov/19753737/))

## What reviewers say

This sugarcane-derived oil is widely praised as a "holy grail" for its lightweight, non-greasy texture that mimics the skin's natural moisture. Users with sensitive and acne-prone skin frequently report that it hydrates without clogging pores, while many appreciate its versatility as a multi-purpose treatment for face, body, and hair. This summary is based on a very large amount of data and should definitely be taken into account.

- Liked: Lightweight non-greasy (mostly mentioned)
- Liked: Multi-purpose versatility (often mentioned)
- Liked: Softens skin texture (often mentioned)
- Liked: Soothing gentle (sometimes noted)
- Disliked: Packaging pump issues (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Insufficient hydration (rarely noted)
- Disliked: Price point (rarely noted)

## Questions and answers

### How well does Biossance 100% Squalane Oil work for sensitive skin?

This oil works as an average fit for your sensitive skin by offering gentle moisture to keep your skin smooth, though it lacks targeted ingredients for redness and irritation. Products that fit this skin better need soothing ingredients like fermented Centella Asiatica and Cica Ceramide to calm redness while strengthening the skin barrier.
Sources: [Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/), [Journal of Nanobiotechnology, 2025](https://pubmed.ncbi.nlm.nih.gov/40001122/)

### Which ingredients make this oil a good fit for sensitive skin?

Squalane makes this oil safe for sensitive skin because it lacks harsh ingredients and helps smooth skin texture. However, since it lacks specialized ingredients to target redness and irritation, a product for this skin needs soothing ingredients like fermented Centella Asiatica, Cica Ceramide, and nourishing oils.
Sources: [Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/), [Journal of Nanobiotechnology, 2025](https://pubmed.ncbi.nlm.nih.gov/40001122/)

### What does Squalane do for sensitive skin?

Squalane helps calm sensitive skin by defending against everyday irritation and keeping it smooth and soft. It is unlikely to cause irritation and supports your skin barrier so it stays comfortable and hydrated.
Sources: [International Journal of Molecular Sciences, 2017](https://pubmed.ncbi.nlm.nih.gov/29280987/)

### What does Squalane Oil do for sensitive skin?

Squalane oil helps keep sensitive skin soft, smooth, and well-hydrated while protecting the skin barrier. Because it acts as a gentle antioxidant and anti-inflammatory agent, it is unlikely to irritate easily and may help calm redness or dryness.
Sources: [Journal of Nanobiotechnology, 2025](https://pubmed.ncbi.nlm.nih.gov/40001122/), [Molecules, 2009](https://pubmed.ncbi.nlm.nih.gov/19169201/)

### Where does this oil go in a skincare routine for sensitive skin?

This oil goes into the moisturizer step in the evening routine, helping to keep sensitive skin soft and smooth safely. Sensitive skin requires a product of this type that also includes specialized calming ingredients to reduce redness and irritation.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/)

### Can I use this oil with retinol, and in what order?

You can use this oil with retinol by applying the oil after your retinol to help lock in moisture and keep your skin soft. Squalane is safe for your sensitive skin because it lacks harsh ingredients, though this product needs extra soothing and calming ingredients to truly target redness and irritation.

### How often should I use this oil?

You can use this oil daily as it is safe for your sensitive skin, though it lacks specialized ingredients to target redness and irritation. To better address sensitive skin, products of this type need calming and soothing ingredients that actively target redness and irritation.
Sources: [Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/)

### Can this oil clog pores, cause breakouts or purging for sensitive skin?

This oil is unlikely to cause breakouts for sensitive skin because it is safe and free of harsh ingredients, though a few shoppers have reported occasional breakouts. Sensitive skin needs lightweight, non-clogging hydrators and calming ingredients that soothe redness and irritation.

## Alternatives for sensitive skin

- [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/uk/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/sensitive-skin) — Superior fit — £14.74 at Amazon
- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/uk/p/cosrx/advanced-snail-96-mucin-power-essence/for/sensitive-skin) — Superior fit — £12.21 at Amazon
- [belif The True Cream Aqua Bomb](https://lovi.care/skincare/uk/p/belif/the-true-cream-aqua-bomb/for/sensitive-skin) — High fit — £32.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/uk/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — £14.99 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/uk/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — £17.91 at Amazon
- Moisturizer with Sun Protection: [Clinique Mineral Sunscreen Fluid for Face SPF 50](https://lovi.care/skincare/uk/p/clinique/broad-spectrum-spf-50-mineral-sunscreen-fluid-for-face/for/sensitive-skin) — Superior fit — £21.00 at Amazon

## Where to buy

- Amazon.co.uk: £21.60 (https://www.amazon.co.uk/dp/B07658MRWW?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: £13.50 (https://www.lookfantastic.com/p/biossance-100-squalane-oil-100ml/12766628/)
Prices checked 16 Oct – 6 Nov 2026.

## Ingredients

Squalane, Squalane Oil
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/biossance/100-squalane-oil/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/biossance/100-squalane-oil/for/sensitive-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/biossance/100-squalane-oil/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/biossance/100-squalane-oil/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/biossance/100-squalane-oil/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/biossance/100-squalane-oil/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/biossance/100-squalane-oil/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/biossance/100-squalane-oil/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/biossance/100-squalane-oil/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/biossance/100-squalane-oil/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/biossance/100-squalane-oil/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/biossance/100-squalane-oil/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/biossance/100-squalane-oil/for/sensitive-skin