Biossance 100% Squalane Oil for mature skin
Squalane- Squalane Oil
Average
- AverageNormal Skin Fit
- AverageEffectiveness
- ExcellentSafety
Works for mature skin; other products fit it better.
This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate moisturizing for your normal skin due to squalane, which hydrates and smooths skin texture, but it does not directly address your concerns with wrinkles and fine lines.
- While squalane provides emollient action suitable for normal skin, the formula lacks additional ingredients for comprehensive skin nourishment.
- The product is safe for your normal skin, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing squalane.
People Say
★4.7Overall rating based on 2.5k+ reviewsThis sugarcane-derived oil is widely praised as a "holy grail" for its lightweight, non-greasy texture that mimics the skin's natural moisture. Users with sensitive and acne-prone skin frequently report that it hydrates without clogging pores, while many appreciate its versatility as a multi-purpose treatment for face, body, and hair. This summary is based on a very large amount of data and should definitely be taken into account.
Highlights
Lightweight non-greasy Mostly Mentioned
- “soaks in right away”
- “doesn't feel heavy”
- “leaves a nice glow not grease”
- “feels like nothing on skin”
Multi-purpose versatility Often Mentioned
- “tames frizzy hair”
- “great on dry cuticles”
- “mixes well with foundation”
- “healed cracked elbows”
Softens skin texture Often Mentioned
- “skin feels like velvet”
- “plumps fine lines”
- “makes face super soft”
- “got rid of dry patches”
Soothing gentle Sometimes Noted
- “stopped the flaking”
- “no stinging on sensitive skin”
- “safe for fungal acne”
Packaging pump issues Sometimes Noted
- “pump leaks everywhere”
- “dispenses too much product”
- “messy cap”
- “bottle gets oily”
Caused breakouts Rarely Noted
- “gave me cystic acne”
- “caused tiny whiteheads”
- “clogged my pores”
- “rash appeared after use”
Insufficient hydration Rarely Noted
- “sat on top of skin”
- “still felt dry later”
- “needed a cream over it”
- “too thin for winter”
Price point Rarely Noted
- “pricy for just squalane”
- “The Ordinary is cheaper”
- “not worth the splurge”
- “paying for the brand”
Sources: lovi.care, biossance.com, sephora.ph, kohls.com, influenster.com, sephora.com, and more
Questions and answers
How well does Biossance 100% Squalane Oil work for mature skin?
Biossance 100% Squalane Oil works moderately well for mature skin because it provides hydration and smooths skin texture, though it does not directly target wrinkles and fine lines. A product for this skin type needs potent ingredients that address lines alongside rich emollients, humectants, peptides, and antioxidants to properly nourish and maintain moisture balance.
Which ingredients make this facial oil a good fit for mature skin?
Squalane makes this facial oil a good fit for mature skin because it hydrates and smooths skin texture while being very gentle. However, to work well for mature skin, a product of this type needs additional ingredients like peptides, antioxidants, or vitamins that help smooth wrinkles and fine lines.
What does Squalane do for mature skin?
Squalane helps keep mature skin feeling soft and smooth by boosting moisture and protecting the skin barrier. It also provides antioxidant support that helps improve the look of fine lines and wrinkles over time.
Journal of Nanobiotechnology, 2025Journal of Nanoscience and Nanotechnology, 2010
What does Squalane Oil do for mature skin?
Squalane oil helps keep mature skin soft and smooth while supporting skin barrier health and elasticity. Regular use may also improve skin moisture and help reduce the look of fine lines and wrinkles. Products for mature skin benefit from including antioxidants and ingredients that support collagen production and barrier repair.
Where does it go in a skincare routine for mature skin?
Biossance 100% Squalane Oil is used as a moisturizer in both your morning and evening routines. Because it only offers moderate hydration without targeting wrinkles, mature skin needs added nourishing ingredients and treatments with active components to properly smooth texture and firm up.
Can I use this facial oil with retinol, and in what order?
You can use this facial oil with retinol by applying the oil after your retinol treatment to help lock in moisture and keep your skin calm. Squalane is very gentle and is unlikely to cause irritation when combined with active ingredients.
How often should I use it?
You can use this squalane oil daily as part of your morning and evening routine to keep your skin soft and smooth. It provides moderate moisturizing, but mature skin also needs additional nourishing ingredients that target wrinkles and fine lines.
Can this facial oil clog pores, cause breakouts or purging for mature skin?
This facial oil is unlikely to cause breakouts for mature skin, as it contains soothing squalane and lacks harsh ingredients. However, rare breakouts may still happen depending on individual skin responses.
What the research says
Topical application of a vitamin C-squalene bioconjugate significantly increased epidermal thickness, type III collagen production, and glycosaminoglycans production in human skin explants compared to free vitamin C and vitamin C-palmitate.
Scientific Reports, 2020Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.
Molecules, 2025Application of squalene/phosphotungstate calcium nanowires (Sql/PWC) oleogel on UVB-irradiated skin decreased epidermal thickness, increased dermal thickness, and promoted the expression of elastin, collagen, and skin barrier markers through antioxidant and anti-inflammatory activities.
Journal of Nanobiotechnology, 2025Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.
Antioxidants, 2025
Why other products fit mature skin better
Topical application of Lactobacillus plantarum-GMNL6 enhanced collagen synthesis and SPTSSA gene expression while reducing melanin synthesis, Staphylococcus aureus biofilm, and Cutibacterium acnes proliferation, leading to clinical improvements in skin moisture, color, spots, wrinkles, UV spots, and porphyrins in human volunteers.
International Journal of Medical Sciences, 2021Nanoemulsions containing Macadamia integrifolia seed oil successfully enhanced skin hydration and reduced wrinkles in human volunteers, outperforming conventional emulsions in skin hydration enhancement.
Nanomaterials, 2024Topical cream containing saffron extract and avocado oil improved wrinkle grading, reduced nasolabial fold area and volume, and increased skin elasticity in twenty healthy volunteers over 12 weeks without allergic reactions.
Journal of Cosmetic Dermatology, 2020
Ingredients
Squalane, Squalane Oil
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
-
Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
-
Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-
Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-
Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-
Medical Board
Cosmetic chemist, SCS, IFSCC member
-
Medical Board, Medical Advisor
Dermatology MD
-
Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
-
Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.