# Biossance 100% Squalane Oil for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: Average · Effectiveness: Average · Safety: Concerning.

Page: https://lovi.care/skincare/uk/p/biossance/100-squalane-oil/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [Biossance](https://lovi.care/skincare/uk/brands/biossance)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other products fit it better.

## Why this fit

- Offers moderate moisturizing for your combination skin, as squalane provides emollient action to hydrate and enhance barrier resilience, though it lacks sufficient humectant ingredients to fully address your oily shine.
- This formula provides general skincare benefits that are mostly supportive for your combination skin type.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/biossance/100-squalane-oil/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/uk/p/biossance/100-squalane-oil/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/uk/p/biossance/100-squalane-oil/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/uk/p/biossance/100-squalane-oil/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/uk/p/biossance/100-squalane-oil/for/acne-prone-skin): Low
- [Skin with dark spots](https://lovi.care/skincare/uk/p/biossance/100-squalane-oil/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/uk/p/biossance/100-squalane-oil/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/biossance/100-squalane-oil/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/biossance/100-squalane-oil/for/oily-acne-prone-skin): Average

## Key ingredients

Squalane, Squalane Oil

## What the research says

- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Topical application of a vitamin C-squalene bioconjugate significantly increased epidermal thickness, type III collagen production, and glycosaminoglycans production in human skin explants compared to free vitamin C and vitamin C-palmitate. ([Scientific Reports, 2020](https://pubmed.ncbi.nlm.nih.gov/33037252/))
- Application of squalene/phosphotungstate calcium nanowires (Sql/PWC) oleogel on UVB-irradiated skin decreased epidermal thickness, increased dermal thickness, and promoted the expression of elastin, collagen, and skin barrier markers through antioxidant and anti-inflammatory activities. ([Journal of Nanobiotechnology, 2025](https://pubmed.ncbi.nlm.nih.gov/40001122/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))

## What reviewers say

This sugarcane-derived oil is widely praised as a "holy grail" for its lightweight, non-greasy texture that mimics the skin's natural moisture. Users with sensitive and acne-prone skin frequently report that it hydrates without clogging pores, while many appreciate its versatility as a multi-purpose treatment for face, body, and hair. This summary is based on a very large amount of data and should definitely be taken into account.

- Liked: Lightweight non-greasy (mostly mentioned)
- Liked: Multi-purpose versatility (often mentioned)
- Liked: Softens skin texture (often mentioned)
- Liked: Soothing gentle (sometimes noted)
- Disliked: Packaging pump issues (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Insufficient hydration (rarely noted)
- Disliked: Price point (rarely noted)

## Questions and answers

### How well does Biossance 100% Squalane Oil work for combination skin?

Biossance 100% Squalane Oil is an average fit for your combination skin because it provides moderate moisture and helps strengthen your skin barrier, but it lacks enough water-attracting ingredients to fully handle oily shine. To work best for combination skin, a product of this type needs effective brightening and moisturizing ingredients to reduce oily shine, along with soothing agents, antioxidants, and multiple peptides.
Sources: [Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/), [Scientific Reports, 2020](https://pubmed.ncbi.nlm.nih.gov/33037252/)

### Which ingredients make this oil a good fit for combination skin?

Squalane and Squalane Oil make this oil work for your combination skin by giving it moderate moisture and strengthening your skin barrier. To be a better fit for this skin type, a product of this type needs brightening ingredients and water-attracting ingredients that reduce oily shine without irritation.
Sources: [Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/), [Scientific Reports, 2020](https://pubmed.ncbi.nlm.nih.gov/33037252/)

### What does Squalane do for combination skin?

Squalane helps keep combination skin soft and smooth by locking in moisture without feeling heavy or greasy. It supports the skin barrier and provides lightweight hydration that works well for both dry and oily areas.
Sources: [Skin Health and Disease, 2024](https://pubmed.ncbi.nlm.nih.gov/39355739/), [Journal of Nanobiotechnology, 2025](https://pubmed.ncbi.nlm.nih.gov/40001122/)

### What does Squalane Oil do for combination skin?

Squalane oil helps keep combination skin soft and smooth without feeling heavy or greasy. It supports your skin barrier and provides lightweight moisture that balances dry and oily areas.
Sources: [International Journal of Molecular Sciences, 2017](https://pubmed.ncbi.nlm.nih.gov/29280987/)

### Where does this oil go in a skincare routine for combination skin?

Biossance 100% Squalane Oil goes near the end of your routine to lock in moisture and support your skin barrier. Because it provides moderate moisture without enough water-drawing ingredients to handle oily shine, combination skin also needs hydrating ingredients like glycerin or hyaluronic acid to stay balanced.
Sources: [Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/), [Scientific Reports, 2020](https://pubmed.ncbi.nlm.nih.gov/33037252/)

### Can I use this oil with retinol, and in what order?

You can use this oil with retinol by applying the oil after your retinol to help keep your skin soft and comfortable. This type of skin also needs ingredients that pull in moisture to fully control oily shine.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this oil?

You can use this oil daily as part of your morning or evening routine to help keep your combination skin soft and moisturized. Because it lacks ingredients that draw in moisture, a combination skin type like yours also needs hydrating ingredients to fully balance oily shine.
Sources: [Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/), [Scientific Reports, 2020](https://pubmed.ncbi.nlm.nih.gov/33037252/)

### Can this oil clog pores, cause breakouts or purging for combination skin?

Biossance 100% Squalane Oil is unlikely to cause breakouts for combination skin, though reviewers mention a low risk of pimples. This oil keeps your skin soft and smooth, but a product of this type needs extra water-attracting ingredients to properly hydrate combination skin while managing oily shine.

## Alternatives for combination skin

- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/uk/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/combination-skin) — Superior fit — £11.90 at Amazon
- [The Ordinary Natural Moisturizing Factors + HA](https://lovi.care/skincare/uk/p/the-ordinary/natural-moisturizing-factors-ha/for/combination-skin) — High fit — £11.40 at Amazon
- [Anua Heartleaf 78% Soothing Cream](https://lovi.care/skincare/uk/p/anua/heartleaf-78-soothing-cream/for/combination-skin) — High fit — £29.40 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/uk/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — £14.99 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/uk/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — £30.37 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/uk/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — £14.80 at Amazon

## Where to buy

- Amazon.co.uk: £21.60 (https://www.amazon.co.uk/dp/B07658MRWW?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: £13.50 (https://www.lookfantastic.com/p/biossance-100-squalane-oil-100ml/12766628/)
Prices checked 16 Oct – 6 Nov 2026.

## Ingredients

Squalane, Squalane Oil
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/biossance/100-squalane-oil/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/biossance/100-squalane-oil/for/combination-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/biossance/100-squalane-oil/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/biossance/100-squalane-oil/for/combination-skin
- France: https://lovi.care/skincare/fr/p/biossance/100-squalane-oil/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/biossance/100-squalane-oil/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/biossance/100-squalane-oil/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/biossance/100-squalane-oil/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/biossance/100-squalane-oil/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/biossance/100-squalane-oil/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/biossance/100-squalane-oil/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/biossance/100-squalane-oil/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/biossance/100-squalane-oil/for/combination-skin