# Biologique Recherche Crème Dermopurifiante for acne-prone skin

**Lovi Fit: Average fit for acne-prone skin.**
Combination Skin Fit: Average · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/uk/p/biologique-recherche/creme-dermopurifiante/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [Biologique Recherche](https://lovi.care/skincare/uk/brands/biologique-recherche)
Category: [Serums and treatments](https://lovi.care/skincare/uk/best/serums)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for acne-prone skin; other serums fit it better.

## Why this fit

- This formulation offers moderate suitability for your combination skin, as niacinamide and Enantia Chlorantha Bark Extract provide seboregulating action to help mattify and reduce blemishes. Arctium Lappa Root Extract also contributes to managing acne and breakouts, though stronger ingredients might be needed for optimal results in all areas.
- The product is safe for your combination skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.
- Functionally, it provides excellent treatment for oily and acne-prone skin due to the presence of niacinamide and oleanolic acid in concentrations that help to mattify and reduce blemishes.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/biologique-recherche/creme-dermopurifiante/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/uk/p/biologique-recherche/creme-dermopurifiante/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/uk/p/biologique-recherche/creme-dermopurifiante/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/uk/p/biologique-recherche/creme-dermopurifiante/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/uk/p/biologique-recherche/creme-dermopurifiante/for/acne-prone-skin): Average (this page)
- [Skin with dark spots](https://lovi.care/skincare/uk/p/biologique-recherche/creme-dermopurifiante/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/uk/p/biologique-recherche/creme-dermopurifiante/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/biologique-recherche/creme-dermopurifiante/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/biologique-recherche/creme-dermopurifiante/for/oily-acne-prone-skin): Average

## Key ingredients

Niacinamide, Mimosa Tenuiflora Extract, Centella Asiatica Extract, Arnica Montana Extract, Salicylic Acid

## What the research says

- Arctigenin improved C. acnes-induced acne inflammation in mice by regulating E2 secretion and inhibiting the NLRP3 inflammasome signaling pathway through targeting CYP19A1. ([Chemical Biology & Drug Design, 2024](https://pubmed.ncbi.nlm.nih.gov/39090783/))
- Polymeric micelles of oleanolic acid applied around the eyes of 23 female subjects for 8 weeks significantly improved all five optical profilometry skin parameters and visual evaluation scores without causing skin irritation. ([Nanoscale Research Letters, 2020](https://pubmed.ncbi.nlm.nih.gov/32572634/))
- Twice daily application of a multitargeted dermocosmetic cream provided comparable efficacy to benzoyl peroxide 5% gel in reducing inflammatory, non-inflammatory, and total lesions in 150 Caucasian subjects with mild-to-moderate acne over 56 days, while demonstrating superior skin tolerability. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Chitosan/Mimosa tenuiflora bio-composite films exhibited improved thermal stability, increased water-uptake ability, antibacterial properties against Escherichia Coli and Micrococcus, and were non-toxic in cytotoxicity assays. ([International Journal of Biological Macromolecules, 2016](https://pubmed.ncbi.nlm.nih.gov/27693339/))
- Arabinogalactan-enriched fractions isolated from Mimosa tenuiflora bark significantly stimulated mitochondrial activity and proliferation in human primary dermal fibroblasts while having minor influence on HaCaT keratinocytes. ([Journal of Ethnopharmacology, 2009](https://pubmed.ncbi.nlm.nih.gov/19505559/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Gels containing 1% Arnica montana L. flower extract successfully enhanced the volume of the lips and face with a reduction of wrinkles in humans. ([International Journal of Cosmetic Science, 2023](https://pubmed.ncbi.nlm.nih.gov/35984685/))
- Topical application of Arnica montana ointment reduced the inflammatory response and oxidative damage in mice exposed to UVB radiation compared to untreated UVB-exposed skin. ([Cutaneous and Ocular Toxicology, 2020](https://pubmed.ncbi.nlm.nih.gov/32183539/))
- The protocol combining microcurrent with topical Arnica montana reduces inflammation, increases myofibroblast proliferation, and decreases macrophage presence in rats with skin lesions compared to controls. ([International Journal of Experimental Pathology, 2023](https://pubmed.ncbi.nlm.nih.gov/36752313/))
- Cryotherapy with liquid nitrogen achieved a higher cure rate (39%) than salicylic acid (24%) and a wait-and-see approach (16%) for cutaneous warts at 13 weeks in primary care patients. ([CMAJ, 2010](https://pubmed.ncbi.nlm.nih.gov/20837684/))
- A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase. ([BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/))
- Treatment with 2% supramolecular salicylic acid hydrogel resulted in a regression and markedly improvement rate of 51.01% compared to 43.10% for Adapaline gel in patients with mild to moderate facial acne vulgaris, showing no significant difference in efficacy. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590107/))

## Why other serums fit acne-prone skin better

- Topical nicotinamide plus an antibacterial adhesive agent and zinc-pyrrolidone carboxylic acid combined with adapalene significantly reduced noninflammatory acne lesions by the second week of therapy compared to placebo with adapalene in patients with moderate acne vulgaris. ([The Journal of Clinical and Aesthetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32983333/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))

## What reviewers say

Users with oily, acne-prone, and congested skin frequently report that this cream effectively regulates sebum and clears breakouts without causing dryness. The distinct, often-mentioned yeasty scent is a common drawback, but the majority of users find the balancing, purifying, and redness-reducing benefits outweigh this sensory aspect.

- Liked: Clears acne (mostly mentioned)
- Disliked: Unpleasant scent (mostly mentioned)
- Liked: Balances oil production (often mentioned)
- Disliked: High price (often mentioned)
- Liked: Hydrates without greasiness (sometimes noted)
- Liked: Refines texture (sometimes noted)
- Liked: Soothes redness (sometimes noted)
- Disliked: Initial reaction (rarely noted)
- Disliked: Reformulation concerns (rarely noted)
- Disliked: Texture issues (rarely noted)

## How to apply

- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Crème Dermopurifiante work for acne-prone skin?

Biologique Recherche Crème Dermopurifiante works moderately well for acne-prone skin, helping to mattify and reduce blemishes with ingredients like niacinamide and salicylic acid. Because other products may fit this skin type better, acne-prone skin often needs stronger clarifying ingredients and soothing plant extracts like propolis or zinc PCA to clear breakouts and maintain balance.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/), [Chemical Biology & Drug Design, 2024](https://pubmed.ncbi.nlm.nih.gov/39090783/)

### Which ingredients make this cream a good fit for acne-prone skin?

Niacinamide, salicylic acid, and oleanolic acid make this cream a good fit because they help control oil and reduce blemishes. To work even better for acne-prone skin, this type of product also needs strong targeted ingredients like propolis or zinc PCA to provide optimal care for breakouts while keeping the skin balanced.
Sources: [Nanoscale Research Letters, 2020](https://pubmed.ncbi.nlm.nih.gov/32572634/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/)

### What does Niacinamide do for acne-prone skin?

Niacinamide helps acne-prone skin by reducing both inflamed and uninflamed breakouts and calming redness. It is also very helpful for keeping oily skin balanced by cutting down on excess oil production, and it is well tolerated by most people.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38299457/), [Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/38725769/)

### What does Mimosa Tenuiflora Extract do for acne-prone skin?

Mimosa Tenuiflora Extract helps support skin repair and encourages cell activity, which may benefit acne-prone skin dealing with lingering marks. Because this extract is typically found in wound-healing treatments, acne-prone skin using products of this type also needs ingredients that clear pores and calm active breakouts.
Sources: [Journal of Ethnopharmacology, 2009](https://pubmed.ncbi.nlm.nih.gov/19505559/), [Journal of Ethnopharmacology, 2007](https://pubmed.ncbi.nlm.nih.gov/17088036/)

### Where does this cream go in a skincare routine for acne-prone skin?

This treatment goes in the evening routine after cleansing and toning, and can also be used weekly depending on your skin's tolerance. While it helps reduce blemishes and oiliness with ingredients like niacinamide, acne-prone skin often needs stronger targeted ingredients for optimal results.
Sources: [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/)

### Can I use this cream with retinol, and in what order?

You can use this cream alongside retinol by applying the retinol first at night, letting it dry, and then following with this treatment to help keep breakouts under control. This type of skin also needs stronger ingredients like retinoids or targeted acids for best results on stubborn breakouts.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use this cream?

Use this treatment in the evening as part of your nighttime routine. It is unlikely to irritate your skin, though an acne-prone skin type needs stronger ingredients like higher concentrations of salicylic acid or targeted retinoids for optimal results across all areas.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/)

### Can this cream clog pores, cause breakouts or purging for acne-prone skin?

This cream is unlikely to clog pores or cause purging for acne-prone skin, as it has a safe formula without harsh ingredients. It helps control oil and reduce blemishes with niacinamide and oleanolic acid, though acne-prone skin often needs even stronger clearing ingredients for the best results.
Sources: [Nanoscale Research Letters, 2020](https://pubmed.ncbi.nlm.nih.gov/32572634/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for acne-prone skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/uk/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/acne-prone-skin) — Superior fit — £36.96 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/uk/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/acne-prone-skin) — Superior fit — £24.20 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/uk/p/skinceuticals/c-e-ferulic/for/acne-prone-skin) — Superior fit — £143.35 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/uk/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — £8.13 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/uk/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — £13.98 at Amazon
- Moisturizer: [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/uk/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — £11.90 at Amazon

## Where to buy

No store in United Kingdom has a checked price for this product, so the page shows none.

## Ingredients

Water, Propylene Glycol, Glycerin, Dicaprylyl Carbonate, Butylene Glycol, Sucrose Polystearate, C10-18 Triglycerides, Cetyl Alcohol, 1,2-Hexanediol, Niacinamide, Polyamide-5, Arctium Lappa Root Extract, Betula Alba Bark Extract, Enantia Chlorantha Bark Extract Moambe Jaune Bark Extract, Equisetum Arvense Extract, Mimosa Tenuiflora Bark Extract Acacia Decurrens Bark Extract, Hedera Helix Stem Extract Leaf, Fucus Vesiculosus Extract, Centella Asiatica Extract, Spiraea Ulmaria Extract, Arnica Montana Flower Extract, Rosa Canina Fruit Extract, Achillea Millefolium Extract Common Yarrow Extract, Aesculus Hippocastanum Seed Extract, Lavandula Angustifolia Flower Extract Lavender Flower Extract, Thymus Vulgaris Extract, Myrtus Communis Extract, Onion Bulb Extract, Commiphora Myrrha Extract Resin, Oleanolic Acid, Glycine Soja Oil Soybean Oil, Yeast Extract, Citric Acid, Tocopherol, Sodium Stearoyl Glutamate, Hydrogenated Polyisobutene, Polyacrylate Crosspolymer-6, Caprylyl Glycol, Phenoxyethanol, Sodium Benzoate, Potassium Sorbate, Sorbic Acid
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

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