# Bioderma Sensibio Defensive for dry sensitive skin

**Lovi Fit: High fit for dry sensitive skin.**
Dry Skin Fit: Superior · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/uk/p/bioderma/sensibio-defensive/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [Bioderma](https://lovi.care/skincare/uk/brands/bioderma)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/uk/best/moisturizers)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for dry sensitive skin; a few moisturizers fit it even better.

## Why this fit

- Excellent suitability for your dry and sensitive skin due to the humectant action of glycerin and fructooligosaccharides, complemented by the anti-inflammatory properties of laminaria ochroleuca extract and glycyrrhetinic acid.
- The formula provides moderate moisturizing benefits with glycerin and xylitol, effectively addressing your dry or flaky skin concerns.
- The safety profile is excellent, with no risks of irritation for your dry and sensitive skin due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/bioderma/sensibio-defensive/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/uk/p/bioderma/sensibio-defensive/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/uk/p/bioderma/sensibio-defensive/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/uk/p/bioderma/sensibio-defensive/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/uk/p/bioderma/sensibio-defensive/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/uk/p/bioderma/sensibio-defensive/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/uk/p/bioderma/sensibio-defensive/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/bioderma/sensibio-defensive/for/dry-sensitive-skin): High (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/bioderma/sensibio-defensive/for/oily-acne-prone-skin): Average

## Key ingredients

Glycerin, Glycyrrhetinic Acid, Laminaria Ochroleuca Extract, Tocopherol, Fructooligosaccharides

## What the research says

- A dermo-cosmetic formula containing 2% enoxolone significantly reduced erythema at 24 hours and pain at 30 minutes following non-ablative fractional laser treatment in 10 healthy subjects compared to a moisturizer control. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38622995/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A formulation containing glycerol (5%) and xylitol (5%) applied twice daily for 14 days increased skin hydration, filaggrin protein quantity, interdigitation index, and biomechanical properties, and decreased transepidermal water loss compared to untreated and vehicle-treated skin in twelve volunteers with dry skin. ([Acta Dermato-venereologica, 2017](https://pubmed.ncbi.nlm.nih.gov/27349297/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical application of a cream containing 2.5% glycyrrhetinic acid significantly reduced thigh fat thickness and circumference compared to placebo in healthy women. ([Steroids, 2005](https://pubmed.ncbi.nlm.nih.gov/15894038/))
- Topical application of B-Resorcinol and Glycyrrhetinic acid effectively lightens hand solar lentigines after 4 weeks of treatment both with and without prior fractional laser photothermolysis, showing no statistical difference between the two approaches. ([Journal of Cosmetic Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/27325103/))
- Glycyrrhetinic acid inhibited skin 11 beta-hydroxysteroid dehydrogenase and potentiated the vasoconstrictor action of hydrocortisone. ([Lancet, 1990](https://pubmed.ncbi.nlm.nih.gov/1970371/))
- Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40642809/))
- Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate. ([Contemporary Clinical Trials Communications, 2021](https://pubmed.ncbi.nlm.nih.gov/34471722/))
- Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590207/))

## How to apply

- Could be used as part of your AM or PM routine. Start using this moisturizer 3 times a week and move to daily use if your dry skin tolerates it well.
- Apply this moisturizer after cleansing and toner in the morning, or after your serum in the evening. Always pair it with SPF in the morning.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing it harshly to protect your sensitive skin.
- Apply the moisturizer on slightly damp skin to help with hydration absorption. This also works well for dry and flaky skin types.
- Do a patch test before your first use. Avoid the eye area to prevent any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Sensibio Defensive a great fit for dry sensitive skin?

Bioderma Sensibio Defensive is a great fit because it uses glycerin and fructooligosaccharides to draw moisture into dry skin, while calming extracts help soothe irritation. It has an excellent safety profile with very low risks of irritation, making it gentle and comfortable for sensitive skin.
Sources: [Acta Dermato-venereologica, 2017](https://pubmed.ncbi.nlm.nih.gov/27349297/)

### Which ingredients make this cream a good fit for dry sensitive skin?

This cream is a great fit for your dry sensitive skin because of the moisturizing action of glycerin and xylitol, which helps smooth flaky patches. It also includes soothing ingredients like laminaria ochroleuca extract and glycyrrhetinic acid that help calm your skin.
Sources: [Acta Dermato-venereologica, 2017](https://pubmed.ncbi.nlm.nih.gov/27349297/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38622995/)

### What does Glycerin do for dry sensitive skin?

Glycerin helps dry sensitive skin by drawing moisture into the skin and keeping it there, making the skin soft and smooth. It is very gentle and unlikely to cause irritation while improving how well the skin holds onto water. This type of skin needs ingredients that boost hydration and repair the barrier without causing stinging.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/)

### What does Glycyrrhetinic Acid do for dry sensitive skin?

Glycyrrhetinic Acid helps calm red, irritated areas and soothe dry, sensitive skin. It is gentle on the skin barrier and reduces tightness to leave your face feeling comfortable.

### Where does this cream go in a skincare routine for dry sensitive skin?

This moisturizing treatment goes in the evening routine after your toner and before your moisturizer. Using a daily routine with a good moisturizer helps improve visual dryness and overall skin comfort.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/)

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol, and applying it first helps calm dry skin and makes it easier for your skin to get used to retinol without irritation. Glycerin and xylitol in the formula help keep your skin hydrated while you use retinol.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Acta Dermato-venereologica, 2017](https://pubmed.ncbi.nlm.nih.gov/27349297/)

### How often should I use this cream?

You can use this moisturizing treatment twice a day as part of your morning and evening routines to keep dry and sensitive skin comfortable. Regular daily application helps improve moisture levels and calms irritation.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for dry sensitive skin?

This cream is unlikely to cause breakouts or clog pores on dry sensitive skin, as its safety profile is excellent and it lacks harsh ingredients. It helps keep skin calm and soft while maintaining hydration without heavy oils that typically block pores.
Sources: [Acta Dermato-venereologica, 2017](https://pubmed.ncbi.nlm.nih.gov/27349297/)

### Can I use this cream around the eyes or on my body?

Yes, you can use this moisturizing treatment around the eyes and on your body because its gentle formula has excellent suitability and safety for sensitive skin. It helps soothe and hydrate dry areas without causing irritation, though you should check how your skin feels when applying it to thinner regions.
Sources: [Acta Dermato-venereologica, 2017](https://pubmed.ncbi.nlm.nih.gov/27349297/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38622995/)

### Is this cream fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum). Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for dry sensitive skin

- [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/uk/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/dry-sensitive-skin) — Superior fit — £14.74 at Amazon
- [The Ordinary Natural Moisturizing Factors + HA](https://lovi.care/skincare/uk/p/the-ordinary/natural-moisturizing-factors-ha/for/dry-sensitive-skin) — Superior fit — £11.40 at Amazon
- [L'Occitane Immortelle Divine Cream](https://lovi.care/skincare/uk/p/l-occitane/immortelle-divine-cream/for/dry-sensitive-skin) — Superior fit — £61.50 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/uk/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — £8.29 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/uk/p/clarins/soothing-toning-lotion/for/dry-sensitive-skin) — Superior fit — £17.91 at Amazon
- Moisturizer with Sun Protection: [Real Barrier Mild Sun Cream](https://lovi.care/skincare/uk/p/real-barrier/mild-sun-cream/for/dry-sensitive-skin) — Superior fit — £19.01 at Amazon

## Where to buy

No store in United Kingdom has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Cetearyl Isononanoate, Cetearyl Alcohol, Glyceryl Stearate, Peg-100 Stearate, Mannitol, Xylitol, Rhamnose, Fructooligosaccharides, Laminaria Ochroleuca Extract, Tocopherol, Glycyrrhetinic Acid, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Sodium Hydroxide, Caprylic Capric Triglyceride, 1,2-Hexanediol, Caprylyl Glycol, Pentylene Glycol, Xanthan Gum, Disodium Edta, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/bioderma/sensibio-defensive/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/bioderma/sensibio-defensive/for/dry-sensitive-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/bioderma/sensibio-defensive/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/bioderma/sensibio-defensive/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/bioderma/sensibio-defensive/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/bioderma/sensibio-defensive/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/bioderma/sensibio-defensive/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/bioderma/sensibio-defensive/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/bioderma/sensibio-defensive/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/bioderma/sensibio-defensive/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/bioderma/sensibio-defensive/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/bioderma/sensibio-defensive/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/bioderma/sensibio-defensive/for/dry-sensitive-skin