🇬🇧United Kingdom

Azclear Medicated Lotion for mature skin

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes

Azclear Medicated Lotion

Low

  • AverageNormal Skin Fit
  • AverageEffectiveness
  • ConcerningSafety

A weak match for mature skin; the serums alongside fit it better.

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Offers moderate treatment for your normal skin, as azelaic acid helps reduce blemishes and glycerin provides humectant action, though it lacks sufficient emollient ingredients for optimal results.
  • While azelaic acid offers some benefits for wrinkles and fine lines, its concentration is not specialized enough for significant improvement.

How to apply

  • Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
  • Apply this serum after your toner and before your moisturizer.
  • Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
  • You can apply the serum on dry skin for the best results against fine lines.
  • Always do a patch test before your first use and avoid the sensitive eye area.

People Say

★4.5Overall rating based on 400+ reviews

A common drawback is the product's tendency to pill or ball up when layered with other products.

Highlights

  • Effective acne treatment Mostly Mentioned
    • “clears stubborn acne”
    • “hormonal breakouts substantially smaller”
    • “fixes hormonal acne and oiliness”
  • Pilling and texture Mostly Mentioned
    • “formula does pill a bit”
    • “finicky formula that pills easily”
    • “hard to put sunscreen over it”
  • Reduces redness Often Mentioned
    • “far less red”
    • “calmed my breakout without scarring”
  • Affordable value Sometimes Noted
    • “amazing affordable treatment”
    • “great value”
    • “cheap and effective”
  • Gentle and non-drying Sometimes Noted
    • “doesn't dry my skin out”
    • “less harsh than other treatments”
    • “hydrating but not greasy”
  • Stinging sensation Sometimes Noted
    • “stung so bad”
    • “skin was a little itchy”
    • “tingling for an hour”
  • Slow absorption Rarely Noted
    • “waiting for it to dry completely”
    • “hard to layer”
    • “leaves a white cast if not rubbed in”

Sources: lovi.care, chemistwarehouse.com.au, chemistdirect.com.au, skinsort.com, sayso.com.au, reddit.com, and more

Questions and answers

Why is Azclear Medicated Lotion a weak match for mature skin?

This lotion is a weak match because it lacks enough softening and smoothing ingredients for optimal results on mature skin, and its azelaic acid concentration is not specialized enough for significant wrinkle improvement. A treatment for mature skin needs potent antioxidants, hydrating components, nourishing oils, peptides, and skin-repairing ingredients.

Which ingredients make this lotion a poor fit for mature skin?

This lotion is a weak match for mature skin because its azelaic acid concentration is not specialized enough for significant improvement and it lacks sufficient softening ingredients. A treatment for mature skin needs potent antioxidants, hydrating components, nourishing oils, peptides, and skin-repairing ingredients for optimal results.

What does Azelaic Acid do for mature skin?

Azelaic acid helps calm inflammation and target early signs of aging like fine lines and uneven tone. It supports skin firmness and texture by providing antioxidant benefits and soothing irritation, which makes it a very good fit for mature skin.

Frontiers in Medicine, 2026Journal of Cosmetic Dermatology, 2022

What does Glycerin do for mature skin?

Glycerin helps keep mature skin feeling soft and smooth by drawing moisture into the outer layer and locking it in. This daily hydration boost supports the skin barrier, keeping dry areas comfortable and protected against irritation.

The British Journal of Dermatology, 2008Clinical, Cosmetic and Investigational Dermatology, 2017

Where does this lotion go in a skincare routine for mature skin?

This lotion goes in the evening routine as a treatment step, typically after cleansing and toning and before moisturizing. Because it is a weak match for mature skin, a product of this type needs rich smoothing and firming ingredients like peptides, retinol, or nourishing oils to help soften fine lines and keep the skin feeling soft and smooth.

Can I use it with retinol, and in what order?

You can use this treatment alongside retinol by applying the treatment in your evening routine and following it with a rich moisturizer to keep mature skin soft and smooth. Because this product lacks sufficient softening and smoothing ingredients for optimal results on mature skin, it needs extra nourishing oils and rich moisturizers to help prevent dryness.

Clinical, Cosmetic and Investigational Dermatology, 2017

How often should I use this lotion?

Apply this treatment in your evening routine once a week to start, as mature skin needs specialized anti-aging ingredients and rich nourishing ingredients to stay soft and smooth.

Can it clog pores, cause breakouts or purging for mature skin?

This treatment is unlikely to clog pores or cause purging for mature skin, though it may leave a stinging sensation on dry spots. A product of this type needs richer softening ingredients and more targeted anti-aging support to properly care for mature skin.

Is this lotion fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

What the research says

  • Azelaic acid nanocrystal hydrogel 10% achieved a higher success rate and greater lesion reduction than azelaic acid cream 20% in patients with mild to moderate facial acne.

    Pharmaceutics, 2021

  • A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

    Clinical, Cosmetic and Investigational Dermatology, 2017

  • Application of 15% azelaic acid gel significantly reduced post-inflammatory erythema and hyperpigmentation, decreased hemoglobin and melanin content, improved quality of life, and contributed to acne improvement in patients with mild to moderate acne compared to placebo.

    Dermatology and Therapy, 2024

  • Topical application of a dermocosmetic containing Myrtus communis extract and azelaic acid reduced acne relapses and helped maintain remission compared to a light moisturizing cream in adult females in the acne maintenance phase over 16 weeks.

    Journal of the European Academy of Dermatology and Venereology, 2023

  • Topical administration of 20% azelaic acid cream and 5% tranexamic acid solution comparably improved acne-related postinflammatory hyperpigmentation in patients with acne vulgaris, while tranexamic acid demonstrated a significantly better safety profile at week 4.

    Journal of Research in Medical Sciences, 2023

  • Azelaic acid 15% gel showed comparable efficacy to adapalene 0.1% gel in reducing lesions, severity, and Dermatology Life Quality Index in women with adult acne, with significantly lower dryness and scaling, and demonstrated superiority during maintenance compared to no further treatment.

    Journal of the European Academy of Dermatology and Venereology, 2015

  • The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

    Journal of Cosmetic Dermatology, 2020

  • Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

    International Journal of Cosmetic Science, 2001

  • Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.

    Journal of Drugs in Dermatology, 2012

  • Biodegradable wound dressings functionalized with silver nanoparticles showed >99% pathogen growth inhibition, bactericidal effects, free radical scavenging, reduced inflammatory response in macrophages, and accelerated wound healing in animals.

    International Journal of Biological Macromolecules, 2022

  • A topical xanthan gum nanogel containing gamma-oryzanol-loaded nanostructured lipid carriers and nanosized TiO2 and MBBT filters demonstrated high photoprotection with an SPF of 34 and no skin irritation or sensitization in a rat model.

    Pharmaceuticals, 2023

  • Dense chitosan-xanthan membranes associated with multipotent mesenchymal stromal cells accelerated wound healing in Wistar rats compared to untreated conditions, demonstrating safety and feasibility for dermo-epidermal wound treatment.

    Journal of Biomaterials Applications, 2015

Why other serums fit mature skin better

  • A peptide complex stimulated basement membrane protein expressions and significantly improved skin wrinkles at all five measured sites after two weeks in 22 healthy Asian female volunteers older than 40 years.

    International Journal of Molecular Sciences, 2019

  • Treatment with 14% ferulic acid and 12% l-ascorbic acid significantly reduced pigmentation and erythema while improving hydration and elasticity in 20 women with photoaged skin, with neither acid proving definitively more effective overall though ascorbic acid showed slightly greater skin lightening.

    Dermatologic Therapy, 2022

Ingredients

Azelaic Acid, Aluminum, Magnesium Silicate, Colloidal Silicon Dioxide, Glycerin, Phenoxyethanol, Water, Xanthan Gum

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

Scan your face, then any product.

QR code: get the Lovi app
Download on theApp Store Get it onGoogle Play

How does it fit your skin?

Scan your face, then any product: Lovi shows how well it fits you and what fits even better.

QR code: get the Lovi app
Download on theApp Store Get it onGoogle Play