# AXIS-Y Artichoke Intensive Skin Barrier Ampoule for sensitive skin

**Lovi Fit: High fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/uk/p/axis-y/artichoke-intensive-skin-barrier-ampoule/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [AXIS-Y](https://lovi.care/skincare/uk/brands/axis-y)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/uk/best/moisturizers)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for sensitive skin; a few moisturizers fit it even better.

## Why this fit

- Excellent for your normal skin with sensitivity, as Centella Asiatica Extract and Glycyrrhiza Glabra Root Extract effectively soothe redness and irritation. Sodium Hyaluronate and Beta-Glucan provide superior hydration and barrier support, enhancing skin resilience.
- Glycerin and Aloe Barbadensis Leaf Water further contribute to moisturizing benefits, ensuring your normal skin remains comfortable and well-nourished.
- The formulation is safe for your skin, containing no harsh or prohibited ingredients that could cause irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/axis-y/artichoke-intensive-skin-barrier-ampoule/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/uk/p/axis-y/artichoke-intensive-skin-barrier-ampoule/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/uk/p/axis-y/artichoke-intensive-skin-barrier-ampoule/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/uk/p/axis-y/artichoke-intensive-skin-barrier-ampoule/for/sensitive-skin): High (this page)
- [Acne-prone skin](https://lovi.care/skincare/uk/p/axis-y/artichoke-intensive-skin-barrier-ampoule/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/uk/p/axis-y/artichoke-intensive-skin-barrier-ampoule/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/uk/p/axis-y/artichoke-intensive-skin-barrier-ampoule/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/axis-y/artichoke-intensive-skin-barrier-ampoule/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/axis-y/artichoke-intensive-skin-barrier-ampoule/for/oily-acne-prone-skin): Average

## Key ingredients

Cynara Scolymus Extract, Sodium Hyaluronate, Centella Asiatica Extract, Glycerin, Glycyrrhiza Glabra Root Extract Licorice Root Extract

## What the research says

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Skin care regimens containing beta-glucan improved hemoglobin index, skin hydration, and transepidermal water loss compared to vehicle control in 20 patients undergoing fractional laser therapy. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- An artichoke extract cosmetic formulation enhanced skin roughness by 19.74% and elasticity by 11.45% in human subjects compared to a placebo cream, alongside exhibiting antioxidant, anti-inflammatory, and anti-aging cellular effects. ([Molecules, 2018](https://pubmed.ncbi.nlm.nih.gov/30360471/))
- Luteolin inhibited the mRNA expression of antimicrobial peptides and increased cornified envelope proteins in TNF-alpha/IL-17A/IFN-gamma-stimulated HaCaT cells by regulating the TRAF6/IkappaB/NF-kappaB signaling pathway. ([Food Science and Biotechnology, 2025](https://pubmed.ncbi.nlm.nih.gov/40655288/))
- Antioxidants and luteolin topically applied decrease UV-B induced apoptosis and downregulate pro-inflammatory cytokines in kindler syndrome keratinocyte cultures. ([Human Molecular Genetics, 2016](https://pubmed.ncbi.nlm.nih.gov/27798104/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Combining 755 nm alexandrite laser with topical licorice gel significantly reduces terminal hair counts compared to alexandrite laser with placebo in women with idiopathic hirsutism. ([Evidence-based Complementary and Alternative Medicine, 2015](https://pubmed.ncbi.nlm.nih.gov/26273313/))
- Licochalcone A activated Nrf2 signaling, elevated cytoprotective enzymes, increased the reduced-to-oxidized glutathione ratio, and decreased reactive oxygen species in human fibroblasts and neutrophils, while a LicA-rich licorice extract lowered UVA-induced oxidative processes in vivo. ([Experimental Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25381913/))
- Bioactive glycyrrhizic acid and oxymatrine ionic liquid self-assembled nanomicelles significantly promoted the transdermal permeation, subcutaneous retention, and anti-photoaging efficacy of palmitoyl pentapeptide-4 in cellular and animal models compared to unformulated peptide. ([Advanced Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39783908/))

## What reviewers say

This ampoule is widely praised as a lightweight, fast-absorbing treatment that excels at soothing irritated skin and repairing a damaged moisture barrier, particularly for oily, acne-prone, and sensitive skin types. Users frequently note that while it provides excellent hydration and redness relief without stickiness, those with very dry skin often need to layer it with a heavier moisturizer.

- Liked: Soothing & calming (mostly mentioned)
- Liked: Hydrating (often mentioned)
- Liked: Lightweight texture (often mentioned)
- Liked: Barrier repair (sometimes noted)
- Disliked: Not moisturizing enough (sometimes noted)
- Disliked: Small size/price (sometimes noted)
- Disliked: Alcohol content (rarely noted)
- Disliked: Breakouts/reaction (rarely noted)

## How to apply

- Use this soothing AM and PM routine every day to keep your normal skin calm. Always remember to apply SPF in the morning after your moisturizer.
- Apply your moisturizer after your toner in the morning, and after your serum in the evening. This step locks in hydration and protects your skin.
- Gently press a small amount of the moisturizer evenly across your face. Avoid rubbing to keep your sensitive skin happy and calm.
- You can apply this gentle formula on dry or slightly damp skin for the best comfort. It works wonderfully on clean skin to soothe redness and irritation.
- Do a patch test before your very first use to check your skin's reaction. Avoid getting the product directly into your eyes .
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes AXIS-Y Artichoke Ampoule a great fit for sensitive skin?

AXIS-Y Artichoke Ampoule is a great fit for sensitive skin because centella asiatica extract and licorice root extract effectively calm redness and irritation. Ingredients like sodium hyaluronate, beta-glucan, and glycerin help provide deep moisture and support the skin barrier, keeping your face comfortable and resilient.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Which ingredients make this ampoule a good fit for sensitive skin?

Centella Asiatica extract and licorice root extract make this ampoule a great fit because they help soothe redness and irritation on sensitive skin. Sodium hyaluronate and beta-glucan also provide deep moisture and support the skin barrier, keeping your face comfortable and resilient.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### What does Artichoke Extract do for sensitive skin?

Artichoke extract helps smooth skin and improve elasticity while providing antioxidant and soothing benefits. It is unlikely to cause irritation and may improve overall skin texture.
Sources: [Molecules, 2018](https://pubmed.ncbi.nlm.nih.gov/30360471/)

### What does Hyaluronic Acid do for sensitive skin?

Hyaluronic acid helps calm and hydrate sensitive skin while supporting the skin barrier to keep it soft and comfortable. Clinical studies show it improves surface moisture and reduces dryness, roughness, and redness without irritation.
Sources: [Journal of Drugs in Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41037531/), [Journal of Cosmetic Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29356277/)

### Where does this ampoule go in a skincare routine for sensitive skin?

This ampoule goes in the evening routine after your toner and before your moisturizer, keeping it simple and safe for your sensitive skin.

### Can I use this ampoule with retinol, and in what order?

Yes, you can use this ampoule with retinol to help keep your skin calm and hydrated. Apply the ampoule before your retinol, or use a barrier-supporting moisturizer first if your skin is easily irritated.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### How often should I use this ampoule?

You can use this treatment in your evening routine, applying it after your toner and before your moisturizer. Daily use helps keep sensitive skin calm and well-hydrated, as soothing extracts and moisture-locking ingredients support your skin barrier.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this ampoule clog pores, cause breakouts or purging for sensitive skin?

This ampoule is unlikely to cause breakouts or clogged pores for sensitive skin, as it contains no harsh or prohibited ingredients that trigger irritation. Reviewers rarely report reactions, and its soothing plant extracts help keep skin calm and comfortable.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can I use this ampoule around the eyes or on my body?

This moisturizing treatment is well-suited for the delicate skin around the eyes and body because its gentle formulation is safe and unlikely to cause irritation. Centella Asiatica Extract and Glycyrrhiza Glabra Root Extract help soothe redness, while Sodium Hyaluronate and Glycerin keep these areas hydrated and comfortable.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Is this ampoule fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (alcohol).

## Alternatives for sensitive skin

- [innisfree Green Tea Seed Hyaluronic Acid Hydrating Serum](https://lovi.care/skincare/uk/p/innisfree/green-tea-seed-hyaluronic-acid-hydrating-serum/for/sensitive-skin) — High fit — £25.00 at Amazon
- [Revision Skincare Hydrating Serum](https://lovi.care/skincare/uk/p/revision-skincare/hydrating-serum/for/sensitive-skin) — High fit — £133.23 at Amazon
- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/uk/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/sensitive-skin) — High fit — £18.40 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/uk/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — £14.99 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/uk/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — £17.91 at Amazon
- Moisturizer with Sun Protection: [Clinique Mineral Sunscreen Fluid for Face SPF 50](https://lovi.care/skincare/uk/p/clinique/broad-spectrum-spf-50-mineral-sunscreen-fluid-for-face/for/sensitive-skin) — Superior fit — £21.00 at Amazon

## Where to buy

- Amazon.co.uk: £16.50 (https://www.amazon.co.uk/dp/B08CBP84MR?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: £14.40 (https://www.lookfantastic.com/p/axis-y-artichoke-intensive-skin-barrier-ampoule-30ml/17735059/)
Prices checked 14 Oct – 5 Nov 2026.

## Ingredients

Water, Aloe Barbadensis Leaf Water, Butylene Glycol, Sodium Hyaluronate, Centella Asiatica Extract, Glycerin, Betaine, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Alcohol, Cynara Scolymus Extract, Sorbitol, Sorbitan Sesquioleate, Hieracium Pilosella Extract, Rheum Palmatum Root Extract, Althaea Rosea Flower Extract, Aloe Barbadensis Leaf Extract, Dimethyl Sulfone, Chlorphenesin, Xanthan Gum, Peg-60 Hydrogenated Castor Oil, Ethylhexylglycerin, Polyglutamic Acid, Beta-Glucan, Arginine, Linum Usitatissimum Seed Extract, Hibiscus Esculentus Fruit Extract, Aloe Barbadensis Leaf Juice, Arctium Lappa Root Extract, Hibiscus Mutabilis Flower Extract, Corchorus Olitorius Leaf Extract, Allantoin, Carbomer, Adenosine, Melaleuca Alternifolia Tree Oil Leaf
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/axis-y/artichoke-intensive-skin-barrier-ampoule/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/axis-y/artichoke-intensive-skin-barrier-ampoule/for/sensitive-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/axis-y/artichoke-intensive-skin-barrier-ampoule/for/sensitive-skin
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