# Advanced Clinicals Retinol Advanced Firming Cream for mature skin

**Lovi Fit: Average fit for mature skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/uk/p/advanced-clinicals/retinol-advanced-firming-cream/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Brand: [Advanced Clinicals](https://lovi.care/skincare/uk/brands/advanced-clinicals)
Category: [Serums and treatments](https://lovi.care/skincare/uk/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for mature skin; other serums fit it better.

## Why this fit

- Suitable for normal skin as retinol helps regulate desquamation and aloe barbadensis leaf juice provides humectant action, though the formula's primary benefits are general hydration rather than directly targeting wrinkles and fine lines.
- The presence of glycerin and aloe barbadensis leaf juice offers hydration, which is supportive but not the main focus for your concerns.
- The product is safe for your skin due to the absence of harsh ingredients and has no risk of irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/uk/p/advanced-clinicals/retinol-advanced-firming-cream/for/oily-skin): Low
- [Dry skin](https://lovi.care/skincare/uk/p/advanced-clinicals/retinol-advanced-firming-cream/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/uk/p/advanced-clinicals/retinol-advanced-firming-cream/for/combination-skin): Low
- [Sensitive skin](https://lovi.care/skincare/uk/p/advanced-clinicals/retinol-advanced-firming-cream/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/uk/p/advanced-clinicals/retinol-advanced-firming-cream/for/acne-prone-skin): Low
- [Skin with dark spots](https://lovi.care/skincare/uk/p/advanced-clinicals/retinol-advanced-firming-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/uk/p/advanced-clinicals/retinol-advanced-firming-cream/for/mature-skin): Average (this page)
- [Dry sensitive skin](https://lovi.care/skincare/uk/p/advanced-clinicals/retinol-advanced-firming-cream/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/uk/p/advanced-clinicals/retinol-advanced-firming-cream/for/oily-acne-prone-skin): Low

## Key ingredients

Retinol, Aloe Barbadensis, Camellia Sinensis, Chamomile, Glycerin

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief. ([Plastic and Reconstructive Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29649056/))
- Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo. ([Journal of Alternative and Complementary Medicine, 2010](https://pubmed.ncbi.nlm.nih.gov/20569031/))
- Topical green tea extract significantly improved clinical symptoms, tear breakup times, and meibomian gland health compared to standard treatment in patients with dry eye and Meibomian Gland Dysfunction. ([Journal of Clinical and Diagnostic Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28384900/))
- Topical low-dose green tea extract reduces UVB-induced p53 expression and apoptosis in human skin keratinocytes compared to placebo. ([Experimental Dermatology, 2009](https://pubmed.ncbi.nlm.nih.gov/18631247/))
- An anti-acne hydrogel containing Aloe barbadensis, Garcinia mangostana, and Camellia sinensis extracts showed superior antiacne and antiblotch activities compared to 1% clindamycin gel in sixty subjects with mild-moderate acne. ([Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/31239743/))
- Apigenin protects against UVA-induced cytotoxicity and senescence in normal human dermal fibroblasts, decreases MMP-1 expression, and when applied topically as a cream in human subjects, increases dermal density and elasticity while reducing fine wrinkle length, skin evenness, moisture content, and transepidermal water loss compared to control cream. ([International Journal of Molecular Medicine, 2016](https://pubmed.ncbi.nlm.nih.gov/27279007/))
- Topical chamomile oil combined with a night splint significantly improved the symptomatic and functional status of patients with severe carpal tunnel syndrome compared to placebo, while electrodiagnostic parameters showed no significant changes. ([Complementary Therapies in Clinical Practice, 2015](https://pubmed.ncbi.nlm.nih.gov/26573447/))
- German chamomile solution applied twice a day healed peristomal skin lesions significantly faster than once-a-day 1% hydrocortisone ointment in colostomy patients, with a mean healing time of 8.89 days versus 14.53 days. ([Ostomy/wound Management, 2011](https://pubmed.ncbi.nlm.nih.gov/21617262/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))

## Why other serums fit mature skin better

- A peptide complex stimulated basement membrane protein expressions and significantly improved skin wrinkles at all five measured sites after two weeks in 22 healthy Asian female volunteers older than 40 years. ([International Journal of Molecular Sciences, 2019](https://pubmed.ncbi.nlm.nih.gov/31861912/))
- A triple peptide complex synergistically stimulated collagen IV production in aged human fibroblasts and reduced periorbital wrinkle parameters compared to placebo in healthy Caucasian volunteers. ([Journal of Cosmetic Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20618556/))
- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))

## What reviewers say

Based on a very large amount of data, this product is highly praised for enhancing skin texture, increasing elasticity, and diminishing fine lines, particularly for aging and sensitive skin types. Some users with very dry skin report it can be drying and may require additional moisturizers. The product is frequently noted for its quick absorption, excellent value, and fragrance-free formulation.

- Liked: Absorbs quickly (often mentioned)
- Liked: Great value (often mentioned)
- Liked: Improves skin texture (often mentioned)
- Liked: Fragrance-free formula (sometimes noted)
- Disliked: Causes skin dryness (sometimes noted)
- Disliked: Faulty pump packaging (rarely noted)
- Disliked: Watery consistency (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Advanced Clinicals Retinol Firming Cream work for mature skin?

This cream works for mature skin by providing general hydration and smoothing dry areas, though it is not primarily focused on wrinkles and fine lines. A product of this type for mature skin needs potent antioxidants, specialized anti-aging ingredients, and deep hydrating components to truly target wrinkles.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for mature skin?

Glycerin and aloe barbadensis leaf juice help make this cream a fit for mature skin by providing hydration, while retinol helps regulate skin shedding. To truly fit mature skin well, a product of this type needs high-quality ingredients that effectively target wrinkles and fine lines with potent antioxidants and skin-repairing components.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Retinol do for mature skin?

Retinol helps smooth out fine lines and wrinkles while improving overall skin thickness and firmness over time. It may also cause temporary dryness, scaling, or stinging as your skin gets used to it.
Sources: [Archives of Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17515510/), [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/)

### What does Aloe Vera do for mature skin?

Aloe vera helps smooth out fine lines and wrinkles by supporting collagen production, keeping mature skin feeling soft and elastic. It is unlikely to cause irritation and may improve skin firmness over time.
Sources: [Journal of Oleo Science, 2009](https://pubmed.ncbi.nlm.nih.gov/19915322/), [Annals of Dermatology, 2009](https://pubmed.ncbi.nlm.nih.gov/20548848/)

### Where does this cream go in a skincare routine for mature skin?

This treatment goes in the evening routine after cleansing and toning, and before moisturizing. To better target lines and wrinkles on mature skin, this type of product needs a formula with stronger anti-aging actives.

### Can I use this cream with vitamin C, and in what order?

You can use this cream alongside vitamin C by applying vitamin C in the morning and this treatment at night, as this product is safe for your skin due to the absence of harsh ingredients and has no risk of irritation.

### How often should I use this cream?

This treatment is used in the evening once a day, and mature skin needs a product with strong wrinkle-smoothing ingredients and targeted anti-aging actives instead of general hydration. It has a great safety profile with no harsh ingredients, making it unlikely to cause irritation.
Sources: [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/)

### Can this cream clog pores, cause breakouts or purging for mature skin?

This cream is unlikely to cause purging or breakouts on mature skin since it has a safe profile without harsh ingredients, though it provides general hydration rather than targeting fine lines. A product of this type needs targeted anti-aging ingredients like retinol and potent peptides to truly smooth and firm mature skin.

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for mature skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/uk/p/skinceuticals/c-e-ferulic/for/mature-skin) — Superior fit — £143.35 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/uk/p/neogen-dermalogy/real-vita-c-serum/for/mature-skin) — High fit — £25.95 at Amazon
- [La Mer The Regenerating Serum](https://lovi.care/skincare/uk/p/la-mer/the-regenerating-serum/for/mature-skin) — High fit — £372.06 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/uk/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — £14.99 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/uk/p/some-by-mi/snail-truecica-miracle-repair-toner/for/mature-skin) — Superior fit — £13.98 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/uk/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/mature-skin) — Superior fit — £38.50 at Amazon

## Where to buy

No store in United Kingdom has a checked price for this product, so the page shows none.

## Ingredients

Water, Mineral Oil, Cetearyl Alcohol, Glyceryl Stearate Se, Isopropyl Myristate, Glycerin, Butylene Glycol, Ceteareth-20, Caprylic Capric Triglyceride, Retinol, Aloe Barbadensis Leaf Juice, Camellia Sinensis Leaf Extract, Anthemis Nobilis Flower Extract, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Disodium Edta, Maltodextrin, Phenoxyethanol, Iodopropynyl Butylcarbamate, Caprylyl Glycol, Sodium Hydroxide
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/advanced-clinicals/retinol-advanced-firming-cream/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/advanced-clinicals/retinol-advanced-firming-cream/for/mature-skin (this page)
- Ireland: https://lovi.care/skincare/ie/p/advanced-clinicals/retinol-advanced-firming-cream/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/advanced-clinicals/retinol-advanced-firming-cream/for/mature-skin
- France: https://lovi.care/skincare/fr/p/advanced-clinicals/retinol-advanced-firming-cream/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/advanced-clinicals/retinol-advanced-firming-cream/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/advanced-clinicals/retinol-advanced-firming-cream/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/advanced-clinicals/retinol-advanced-firming-cream/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/advanced-clinicals/retinol-advanced-firming-cream/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/advanced-clinicals/retinol-advanced-firming-cream/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/advanced-clinicals/retinol-advanced-firming-cream/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/advanced-clinicals/retinol-advanced-firming-cream/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/advanced-clinicals/retinol-advanced-firming-cream/for/mature-skin