# Retinol and acetyl hexapeptide-3

Page: https://lovi.care/skincare/uk/ingredients/retinol-and-acetyl-hexapeptide-3

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Depends on the strength

Use them at different times of day with [retinol](https://lovi.care/skincare/uk/ingredients/retinol) at night and peptides in the morning, because combining strong retinoids and peptides can cause irritation. Retinol speeds up skin renewal while peptides help build firm, smooth skin, but mixing them all at once might overwhelm the face. The shopper can switch to a gentler retinol strength or leave more time between applying the two products.

- [All about retinol](https://lovi.care/skincare/uk/ingredients/retinol)
- [All about acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3)

### [Retinol](https://lovi.care/skincare/uk/ingredients/retinol) products

- [CeraVe Resurfacing Retinol Serum](https://lovi.care/skincare/uk/p/cerave/resurfacing-retinol-serum/for/dark-spots) — High fit — [£15.64 at Amazon](https://www.amazon.co.uk/dp/B0B913JC2W?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [RoC Retinol Correxion Deep Wrinkle Night Cream](https://lovi.care/skincare/uk/p/roc/retinol-correxion-deep-wrinkle-night-cream/for/dark-spots) — High fit — [£19.34 at Amazon](https://www.amazon.co.uk/dp/B0GXBBV93V?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Paula's Choice 1% Retinol Treatment](https://lovi.care/skincare/uk/p/paula-s-choice/1-retinol-treatment/for/dark-spots) — Superior fit — [£39.97 at Amazon](https://www.amazon.co.uk/dp/B00L5O31VK?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [RoC Retinol Correxion Line Smoothing Eye Cream](https://lovi.care/skincare/uk/p/roc/retinol-correxion-line-smoothing-eye-cream/for/mature-skin) — High fit — [£17.99 at Amazon](https://www.amazon.co.uk/dp/B08GGD7NRN?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Good Molecules Gentle Retinol Cream](https://lovi.care/skincare/uk/p/good-molecules/gentle-retinol-cream/for/mature-skin) — High fit — [£12.03 at Amazon](https://www.amazon.co.uk/dp/B09BST7MMP?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [La Roche-Posay Retinol B3 Serum](https://lovi.care/skincare/uk/p/la-roche-posay/retinol-b3-serum/for/dark-spots) — Average fit — [£38.39 at Amazon](https://www.amazon.co.uk/dp/B07Z9Y4M3C?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [DRMTLGY Retinol Body Lotion](https://lovi.care/skincare/uk/p/drmtlgy/retinol-body-lotion/for/mature-skin) — Average fit
- [RoC Retinol Correxion Deep Wrinkle Serum](https://lovi.care/skincare/uk/p/roc/retinol-correxion-deep-wrinkle-serum/for/oily-skin) — Average fit — [£18.49 at Amazon](https://www.amazon.co.uk/dp/B0GQZ5J61H?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [CeraVe Skin Renewing Retinol Serum](https://lovi.care/skincare/uk/p/cerave/skin-renewing-retinol-serum/for/dark-spots) — Average fit — [£19.29 at Amazon](https://www.amazon.co.uk/dp/B0FM8S8JZY?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Olay Regenerist Retinol 24 Night Moisturizer](https://lovi.care/skincare/uk/p/olay/regenerist-retinol-24-night-moisturizer/for/mature-skin) — Superior fit — [£19.73 at Amazon](https://www.amazon.co.uk/dp/B0852NRDYN?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [cocokind Retinol Body Cream](https://lovi.care/skincare/uk/p/cocokind/retinol-body-cream/for/mature-skin) — Average fit
- [Neutrogena Rapid Wrinkle Repair Regenerating Cream](https://lovi.care/skincare/uk/p/neutrogena/rapid-wrinkle-repair-regenerating-cream/for/mature-skin) — High fit — [£36.99 at Amazon](https://www.amazon.co.uk/dp/B01HOHBS6G?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)

### [Acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3) products

- [The Ordinary Multi-Peptide + Copper Peptides 1% Serum](https://lovi.care/skincare/uk/p/the-ordinary/multi-peptide-copper-peptides-1-serum/for/mature-skin) — High fit — [£28.90 at Amazon](https://www.amazon.co.uk/dp/B0C9DXGXZ3?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [The Ordinary Multi-Peptide + HA Serum](https://lovi.care/skincare/uk/p/the-ordinary/multi-peptide-ha-serum/for/dry-skin) — Superior fit — [£12.72 at Amazon](https://www.amazon.co.uk/dp/B0BLHW7JZM?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Medik8 Liquid Peptides](https://lovi.care/skincare/uk/p/medik8/liquid-peptides/for/oily-acne-prone-skin) — Average fit — [£51.15 at Amazon](https://www.amazon.co.uk/dp/B0DDY3D3QW?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [La Mer The Treatment Lotion](https://lovi.care/skincare/uk/p/la-mer/the-treatment-lotion/for/mature-skin) — Superior fit — [£209.56 at Amazon](https://www.amazon.co.uk/dp/B076ZQ7YVB?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Rhode Peptide Glazing Fluid](https://lovi.care/skincare/uk/p/rhode/peptide-glazing-fluid/for/mature-skin) — High fit — [£35.00 at Amazon](https://www.amazon.co.uk/dp/B0GNNW5QV3?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [The Ordinary Argireline Solution 10%](https://lovi.care/skincare/uk/p/the-ordinary/argireline-solution-10/for/mature-skin) — Average fit — [£7.36 at Amazon](https://www.amazon.co.uk/dp/B072JH13CD?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Good Molecules Super Peptide Serum](https://lovi.care/skincare/uk/p/good-molecules/super-peptide-serum/for/mature-skin) — High fit — [£17.00 at Amazon](https://www.amazon.co.uk/dp/B091MTKS35?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Clinique Smart Clinical Repair Wrinkle Correcting Serum](https://lovi.care/skincare/uk/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/mature-skin) — Average fit — [£46.87 at Amazon](https://www.amazon.co.uk/dp/B09FG9W2LM?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [La Mer The Renewal Oil](https://lovi.care/skincare/uk/p/la-mer/the-renewal-oil/for/mature-skin) — High fit — [£175.50 at Amazon](https://www.amazon.co.uk/dp/B01MTQKM02?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Estée Lauder Micro Essence Treatment Lotion](https://lovi.care/skincare/uk/p/estee-lauder/micro-essence-treatment-lotion/for/oily-acne-prone-skin) — Superior fit — [£42.00 at Amazon](https://www.amazon.co.uk/dp/B0BB44W3QP?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [The INKEY List Collagen Peptide Serum](https://lovi.care/skincare/uk/p/the-inkey-list/collagen-peptide-serum/for/dry-sensitive-skin) — High fit
- [La Mer The Eye Concentrate](https://lovi.care/skincare/uk/p/la-mer/the-eye-concentrate/for/mature-skin) — High fit — [£199.00 at Amazon](https://www.amazon.co.uk/dp/B00438A000?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)

## Questions and answers

### Can you use retinol and acetyl hexapeptide-3 together?

Whether you can use [retinol](https://lovi.care/skincare/uk/ingredients/retinol) and [acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3) together depends on the strength. Strong retinoids should be separated from peptides by alternating usage, such as using a retinoid at night and peptides in the morning, to help avoid irritation.

[American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/) [Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/)

### Which goes first, retinol or acetyl hexapeptide-3?

It depends on the retinol strength, so use them at separate times of day like applying peptides in the morning and retinol at night, or alternate your usage to avoid irritation.

### Are retinol and acetyl hexapeptide-3 good for sensitive skin?

Combining retinol and acetyl hexapeptide-3 depends on the strength because strong retinoids should be separated from peptides on sensitive skin to avoid increased irritation. You can alternate their usage by applying the retinoid at night and peptides in the morning.

## Research on retinol and acetyl hexapeptide-3

- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol · The British Journal of Dermatology, 2019
- [Encapsulation and controlled release of retinol from silicone particles for topical delivery](https://pubmed.ncbi.nlm.nih.gov/29604311/) Retinol · Journal of Controlled Release, 2018
- [A randomized, controlled comparative study of the wrinkle reduction benefits of a cosmetic niacinamide/peptide/retinyl propionate product regimen vs. a prescription 0.02% tretinoin product regimen](https://pubmed.ncbi.nlm.nih.gov/20374604/) Retinol · The British Journal of Dermatology, 2010
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-3 · American Journal of Clinical Dermatology, 2013
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-3 · Annals of Dermatology, 2019
- [The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study](https://pubmed.ncbi.nlm.nih.gov/28150423/) Acetyl hexapeptide-3 · Journal of Cosmetic Dermatology, 2017
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-3 · Journal of Cosmetic and Laser Therapy, 2013
- [Topical application of retinyl propionate, 4 hexyl resorcinol, and niacinamide reverses molecular and clinical features of ageing](https://pubmed.ncbi.nlm.nih.gov/38685700/) Retinol · International Journal of Cosmetic Science, 2024

## Other combinations

- Depends on the strength: [Retinol and niacinamide](https://lovi.care/skincare/uk/ingredients/retinol-and-niacinamide)
- Keep them apart: [Retinol and isopropyl alcohol](https://lovi.care/skincare/uk/ingredients/retinol-and-isopropyl-alcohol)
- Keep them apart: [Retinol and sodium lauryl sulfate](https://lovi.care/skincare/uk/ingredients/retinol-and-sodium-lauryl-sulfate)
- Keep them apart: [Retinol and aha blend glycolic and citric acids](https://lovi.care/skincare/uk/ingredients/retinol-and-aha-blend-glycolic-and-citric-acids)
- Keep them apart: [Retinol and citric acid](https://lovi.care/skincare/uk/ingredients/retinol-and-citric-acid)
- Keep them apart: [Glycolic acid and retinol](https://lovi.care/skincare/uk/ingredients/glycolic-acid-and-retinol)
- Keep them apart: [Retinol and lactic acid](https://lovi.care/skincare/uk/ingredients/retinol-and-lactic-acid)
- Keep them apart: [Retinol and mandelic acid](https://lovi.care/skincare/uk/ingredients/retinol-and-mandelic-acid)
- Keep them apart: [Retinol and salicylic acid](https://lovi.care/skincare/uk/ingredients/retinol-and-salicylic-acid)
- Keep them apart: [Vitamin C and retinol](https://lovi.care/skincare/uk/ingredients/vitamin-c-and-retinol)
- Keep them apart: [Adapalene and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/adapalene-and-acetyl-hexapeptide-3)
- Keep them apart: [Acetyl hexapeptide-3 and granactive retinoid](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-granactive-retinoid)
- Keep them apart: [Acetyl hexapeptide-3 and hydroxypinacolone retinoate](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-hydroxypinacolone-retinoate)
- Keep them apart: [Pro-retinol and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/pro-retinol-and-acetyl-hexapeptide-3)
- Keep them apart: [Retinal and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/retinal-and-acetyl-hexapeptide-3)
- Keep them apart: [Acetyl hexapeptide-3 and retinoid blend](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-retinoid-blend)
- Keep them apart: [Tretinoin and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/tretinoin-and-acetyl-hexapeptide-3)
- Keep them apart: [Vitamin A and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/vitamin-a-and-acetyl-hexapeptide-3)
- Depends on the strength: [Retinol and bio-placenta peptides](https://lovi.care/skincare/uk/ingredients/retinol-and-bio-placenta-peptides)
- Depends on the strength: [Retinol and collagen peptide](https://lovi.care/skincare/uk/ingredients/retinol-and-collagen-peptide)
- Depends on the strength: [Retinol and copper peptide](https://lovi.care/skincare/uk/ingredients/retinol-and-copper-peptide)
- Depends on the strength: [Retinol and hexapeptide](https://lovi.care/skincare/uk/ingredients/retinol-and-hexapeptide)
- Depends on the strength: [Retinol and hexapeptide-9](https://lovi.care/skincare/uk/ingredients/retinol-and-hexapeptide-9)
- Depends on the strength: [Retinol and palmitoyl pentapeptide-4](https://lovi.care/skincare/uk/ingredients/retinol-and-palmitoyl-pentapeptide-4)
- Depends on the strength: [Retinol and palmitoyl tripeptide-1](https://lovi.care/skincare/uk/ingredients/retinol-and-palmitoyl-tripeptide-1)
- Depends on the strength: [Retinol and peptide-rich plasma](https://lovi.care/skincare/uk/ingredients/retinol-and-peptide-rich-plasma)
- Depends on the strength: [Retinol and triple peptide blend](https://lovi.care/skincare/uk/ingredients/retinol-and-triple-peptide-blend)
- Work well together: [Liposome and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/liposome-and-acetyl-hexapeptide-3)
- Work well together: [Acetyl hexapeptide-3 and microcapsule](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-microcapsule)
- Depends on the strength: [Vitamin C and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/vitamin-c-and-acetyl-hexapeptide-3)
- Work well together: [Acetyl hexapeptide-3 and betaine](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-betaine)
- Work well together: [Glycerin and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/glycerin-and-acetyl-hexapeptide-3)
- Work well together: [Acetyl hexapeptide-3 and hyaluronic acid](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-hyaluronic-acid)
- Depends on the strength: [Niacinamide and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/niacinamide-and-acetyl-hexapeptide-3)
- Work well together: [Panthenol and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/panthenol-and-acetyl-hexapeptide-3)
- Work well together: [Bakuchiol and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/bakuchiol-and-acetyl-hexapeptide-3)
- Work well together: [Retinol and bakuchiol](https://lovi.care/skincare/uk/ingredients/retinol-and-bakuchiol)
- Work well together: [Retinol and coenzyme q10](https://lovi.care/skincare/uk/ingredients/retinol-and-coenzyme-q10)
- Work well together: [Retinol and green tea](https://lovi.care/skincare/uk/ingredients/retinol-and-green-tea)
- Work well together: [Retinol and vitamin E](https://lovi.care/skincare/uk/ingredients/retinol-and-vitamin-e)
- Work well together: [Arginine and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/arginine-and-acetyl-hexapeptide-3)
- Work well together: [Acetyl hexapeptide-3 and GABA](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-gaba)
- Work well together: [Silk amino acids and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/silk-amino-acids-and-acetyl-hexapeptide-3)
- Work well together: [Taurine and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/taurine-and-acetyl-hexapeptide-3)
- Work well together: [Acetyl hexapeptide-3 and theanine](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-theanine)
- Keep them apart: [AHA blend glycolic and citric acids and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/aha-blend-glycolic-and-citric-acids-and-acetyl-hexapeptide-3)
- Keep them apart: [Acetyl hexapeptide-3 and citric acid](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-citric-acid)
- Keep them apart: [Glycolic acid and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/glycolic-acid-and-acetyl-hexapeptide-3)
- Keep them apart: [Lactic acid and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/lactic-acid-and-acetyl-hexapeptide-3)
- Keep them apart: [Acetyl hexapeptide-3 and mandelic acid](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-mandelic-acid)
- Work well together: [Coenzyme Q10 and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/coenzyme-q10-and-acetyl-hexapeptide-3)
- Work well together: [Green tea and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/green-tea-and-acetyl-hexapeptide-3)
- Work well together: [Vitamin E and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/vitamin-e-and-acetyl-hexapeptide-3)
- Work well together: [Acetyl hexapeptide-3 and beta-sitosterol](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-beta-sitosterol)
- Work well together: [Ceramide-building complex and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/ceramide-building-complex-and-acetyl-hexapeptide-3)
- Work well together: [Acetyl hexapeptide-3 and cholesterol](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-cholesterol)
- Work well together: [Acetyl hexapeptide-3 and phytosphingosine](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-phytosphingosine)
- Work well together: [Acetyl hexapeptide-3 and phytosterol](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-phytosterol)
- Work well together: [Acetyl hexapeptide-3 and squalene](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-squalene)
- Work well together: [Acetyl hexapeptide-3 and tri-ceramide complex](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-tri-ceramide-complex)
- Keep them apart: [Salicylic acid and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/salicylic-acid-and-acetyl-hexapeptide-3)
- Keep them apart: [Acetyl hexapeptide-3 and baking soda](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-baking-soda)
- Keep them apart: [Acetyl hexapeptide-3 and bleach](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-bleach)
- Keep them apart: [Acetyl hexapeptide-3 and potassium hydroxide](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-potassium-hydroxide)
- Keep them apart: [Acetyl hexapeptide-3 and behenyl alcohol](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-behenyl-alcohol)
- Keep them apart: [Acetyl hexapeptide-3 and isopropyl alcohol](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-isopropyl-alcohol)
- Keep them apart: [Acetyl hexapeptide-3 and polyvinyl alcohol](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-polyvinyl-alcohol)
- Keep them apart: [Copper and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/copper-and-acetyl-hexapeptide-3)
- Keep them apart: [Benzoyl peroxide and retinol](https://lovi.care/skincare/uk/ingredients/benzoyl-peroxide-and-retinol)
- Keep them apart: [Magnesium and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/magnesium-and-acetyl-hexapeptide-3)
- Keep them apart: [Acetyl hexapeptide-3 and zinc](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-zinc)
- Keep them apart: [Acetyl hexapeptide-3 and zinc sulfate](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-zinc-sulfate)
- Keep them apart: [Benzoyl peroxide and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/benzoyl-peroxide-and-acetyl-hexapeptide-3)
- Work well together: [Retinol and ceramide-building complex](https://lovi.care/skincare/uk/ingredients/retinol-and-ceramide-building-complex)
- Work well together: [Retinol and tri-ceramide complex](https://lovi.care/skincare/uk/ingredients/retinol-and-tri-ceramide-complex)
- Keep them apart: [Azelaic acid and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/azelaic-acid-and-acetyl-hexapeptide-3)
- Keep them apart: [Acetyl hexapeptide-3 and protease](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-protease)
- Keep them apart: [Acetyl hexapeptide-3 and superoxide dismutase](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-superoxide-dismutase)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/ingredients/retinol-and-acetyl-hexapeptide-3
- United Kingdom: https://lovi.care/skincare/uk/ingredients/retinol-and-acetyl-hexapeptide-3 (this page)
- Ireland: https://lovi.care/skincare/ie/ingredients/retinol-and-acetyl-hexapeptide-3
- Germany: https://lovi.care/skincare/de/ingredients/retinol-and-acetyl-hexapeptide-3
- France: https://lovi.care/skincare/fr/ingredients/retinol-and-acetyl-hexapeptide-3
- Italy: https://lovi.care/skincare/it/ingredients/retinol-and-acetyl-hexapeptide-3
- Netherlands: https://lovi.care/skincare/nl/ingredients/retinol-and-acetyl-hexapeptide-3
- Spain: https://lovi.care/skincare/es/ingredients/retinol-and-acetyl-hexapeptide-3
- Canada: https://lovi.care/skincare/ca/ingredients/retinol-and-acetyl-hexapeptide-3
- Australia: https://lovi.care/skincare/au/ingredients/retinol-and-acetyl-hexapeptide-3
- Singapore: https://lovi.care/skincare/sg/ingredients/retinol-and-acetyl-hexapeptide-3
- Saudi Arabia: https://lovi.care/skincare/sa/ingredients/retinol-and-acetyl-hexapeptide-3
- United Arab Emirates: https://lovi.care/skincare/ae/ingredients/retinol-and-acetyl-hexapeptide-3